Latest Update：2025/04/18 11:00:02

WATANABE Haruna

Researcher Name: WATANABE Haruna

Div (Section) name/title: Health and Environmental Risk Division（Ecotoxicity Research Section）／Senior Researcher

Research Subject: Development and improvement of methods to evaluate the fate of chemicals in environment (analytical methods) and their effect on aquatic organisms (bioassay).

Degree(s): Ph.D.(Engineering）

Professional Qualification(s): Civil Engineering,Biology,Chemistry

Environmental Speciality Field: Ecotoxicology,Environmental engineering,Chemical risk assessment

Research Subject

Fiscal Year: 2024
- 26831 : Research project on the ecological impact and factor analysis considering vulnerability
- 27002 : Development of ecological risk assessment methods for multiple chemicals based on the similarity of activity/structure and exposure profile
- 27037 : Basic research on ecotoxicity from the viewpoint of molecular to organism or population level
- 27038 : Assessment of effects on marine organisms exposed to microplastics via water and sediment
- 27041 : FY2024 Contract work on the development and validation of new ecotoxicity test methods in OECD and the support for GLP inspection activities
- 27077 : The study for establishing a new fish acute toxicity test concerning animal welfare
- 27079 : Development of novel bioassay technique
- 27123 : Classification of structure similarity and mode of action of chemicals with high chronic toxicity to daphnids
- 27131 : FY2024 Contract work on test method development for endocrine disrupting chemicals
- 27132 : Study on risk assessment of chemicals using effect directed analysis in FY2024
Fiscal Year: 2023
- 26421 : Research project on the ecological impact and factor analysis considering vulnerability
- 26715 : Basic research on ecotoxicity from the viewpoint of molecular to organism or population level
- 26716 : Development of ecological risk assessment methods for multiple chemicals based on the similarity of activity/structure and exposure profile
- 26717 : Profile analysis of ecotoxicity of bioplastic eluates using marine organisms
- 26718 : Study on development of framework for environmental risk assessment of new pharmaceuticals by integrated approaches to testing and assessment (IATA)
- 26719 : Research on utilization of bioassays for management of various water environments
- 26720 : FY2023 Contract work on the development and validation of new ecotoxicity test methods in OECD and the support for GLP inspection activities
- 26755 : FY2023 Contract work on test method development for endocrine disrupting chemicals
- 26756 : FY2023 Contract research work on the development of new assessment method for ecological risk of pesticides
- 26757 : Study on risk assessment of chemicals using effect directed analysis in FY2023
- 26768 : Contract study on the ecotoxicity testing for the development of assessment of chemical mixtures in FY2022
- 26769 : Assessment of effects on marine organisms exposed to microplastics via water and sediment
- 26793 : The study for establishing a new fish acute toxicity test concerning animal welfare
- 26795 : Development of novel bioassay technique
Fiscal Year: 2022
- 25974 : Research project on the ecological impact and factor analysis considering vulnerability
- 26297 : Basic research on ecotoxicity from the viewpoint of molecular to organism or population level
- 26298 : FY2021-2022 Tier 2 Testing for endocrine disrupting chemical (17β-estradiol)
- 26337 : Development of ecological risk assessment methods for multiple chemicals based on the similarity of activity/structure and exposure profile
- 26338 : FY2022 Contract work on test method development for endocrine disrupting chemicals
- 26339 : FY2022 Contract work on the development and validation of new ecotoxicity test methods in OECD and the support for GLP inspection activities
- 26340 : Profile analysis of ecotoxicity of bioplastic eluates using marine organisms
- 26357 : Study on development of framework for environmental risk assessment of new pharmaceuticals by integrated approaches to testing and assessment (IATA)
- 26396 : Study on risk assessment of chemicals using effect directed analysis in FY2022
- 26397 : Contract study on the ecotoxicity testing for the development of assessment of chemical mixtures in FY2022
- 26398 : FY2022 Contract research work on the development of new assessment method for ecological risk of pesticides
- 26399 : Research on utilization of bioassays for management of various water environments
Fiscal Year: 2021
- 25518 : Study on ecological impact and factor analysis considering vulnerability
- 25752 : Basic research on ecotoxicity from the viewpoint of molecular to organism or population level
- 25876 : Developing risk assessment methods for chemicals in sediment that consider exposure routes and bioavailability to benthic organisms
- 25882 : Development of the prediction system for environmental effects by new drugs based on the evaluation results of environmental toxicity by existing drugs
- 25883 : Comparison of various bioassay for testing water quality of ambient water samples
- 25892 : FY2021 Contract work on test method development for endocrine disrupting chemicals
- 25895 : FY2021 Contract work on the development and validation of new ecotoxicity test methods in OECD
- 25897 : FY2021 Contract research work on the development of new assessment method for ecological risk of pesticides
- 25938 : Study on risk assessment of chemicals using effect directed analysis in FY2021
- 25942 : Study on the ecotoxicity testing for the development of assessment of chemical mixtures in FY2021
- 25943 : FY2021-2022 Tier 2 Testing for endocrine disrupting chemical (17β-estradiol)
Fiscal Year: 2020
- 25099 : Research Program on Health and Environmental Safety
- 25124 : Risk Assessment Science Collaboration Office
- 25144 : Project to Build a System Evaluating Ecological Effect Comprehensively and Effectively
- 25362 : Comparison of various bioassay for testing water quality of ambient water samples
- 25363 : Development of the prediction system for environmental effects by new drugs based on the evaluation results of environmental toxicity by existing drugs
- 25364 : FY2019-2020 Tier 2 Testing for endocrine disrupting chemical (17α-ethynylestradiol)
- 25365 : Upgrade of Ecotoxicity Testing and Development of Novel System to Evaluate Ecotoxicological Effects of Chemicals
- 25366 : Development of short-term chronic toxicity tests using marine and estuarine species
- 25379 : Developing risk assessment methods for chemicals in sediment that consider exposure routes and bioavailability to benthic organisms
- 25401 : Study on revision of OECD fish, acute toxicity testing
- 25407 : The development of new ecological risk assessment method for agricultural chemicals
Fiscal Year: 2019
- 24696 : Research Program on Health and Environmental Safety
- 24724 : Project to Build a System Evaluating Ecological Effect Comprehensively and Effectively
- 24756 : Risk Assessment Science Collaboration Office
- 25020 : Upgrade of Ecotoxicity Testing and Development of Novel System to Evaluate Ecotoxicological Effects of Chemicals
- 25021 : Development of short-term chronic toxicity tests using marine and estuarine species
- 25022 : FY2019 Validation research on the amendment of the OECD fish acute toxicity test guideline
- 25042 : Developing risk assessment methods for chemicals in sediment that consider exposure routes and bioavailability to benthic organisms
- 25043 : Investigation of mechanism of mixture toxicity to daphnids using gene expression analysis
- 25050 : Development of the prediction system for environmental effects by new drugs based on the evaluation results of environmental toxicity by existing drugs
- 25051 : Comparison of various bioassay for testing water quality of ambient water samples
- 25089 : FY2019 Investigation on Toxicity Testing and Evaluation Methods of Difficult Chemicals
- 25091 : FY2019 Study on the Development of Assessment Procedure for the Mixture Effects of Chemicals Using Ecotoxicity Testing
- 25092 : FY2019 Contract research work on risk assessment of chemicals using the effect-directed analysis
- 25093 : FY2019 Development of Testing Methods Regarding Endocrine Disrupting Effects of Chemicals
- 25094 : FY2019-2020 Tier 2 Testing for endocrine disrupting chemical (17α-ethynylestradiol)
- 25095 : FY2019 Research on the development of novel methods for the assessment of ecological risk of pesticides in aquatic environment
Fiscal Year: 2018
- 24307 : Project to build a system evaluating ecological effect comprehensively and effectively
- 24339 : Risk Assessment Science Collaboration Office
- 24355 : Research program on health and environmental safety
- 24532 : Upgrade of ecotoxicity testing and development of novel system to evaluate ecotoxicological effects of chemicals
- 24533 : Case study on biological risk in aquatic environment using WET method
- 24534 : FY2017-2018 Tier 2 Biological Tests Regarding Chemicals with Endocrine Disrupting Effects
- 24535 : FY2018 Development of Testing Methods Regarding Endocrine Disrupting Effects of Chemicals
- 24536 : FY2018 Study on the Development of Assessment Procedure for the Mixture Effects of Chemicals Using Ecotoxicity Testing
- 24537 : Investigation on water environment management method using biological responses in FY 2018
- 24538 : Development of short-term chronic toxicity tests using marine and estuarine species
- 24610 : Investigation of mechanism of mixture toxicity to daphnids using gene expression analysis
Fiscal Year: 2017
- 23821 : Project to build a system evaluating ecological effect comprehensively and effectively
- 23847 : Research program on health and environmental safety
- 24067 : Upgrade of ecotoxicity testing and development of novel system to evaluate ecotoxicological effects of chemicals
- 24184 : FY2017 Development of Testing Methods Regarding Endocrine Disrupting Effects of Chemicals
- 24185 : FY2017-2018 Tier 2 Biological Tests Regarding Chemicals with Endocrine Disrupting Effects
- 24186 : FY2017 Investigation on Toxcity Testing of Difficult Test Chemicals
Fiscal Year: 2016
- 23414 : Research program on health and environmental safety
- 23418 : Project to build a system evaluating ecological effect comprehensively and effectively
- 23572 : Upgrade of ecotoxicity testing and development of novel system to evaluate ecotoxicological effects of chemicals
- 23713 : The Study about a New Evaluation System of the Ecological Effect with Chemicals.
- 23812 : Study on toxicity tests for difficult test chemicals (FY2016)
Fiscal Year: 2015
- 23000 : Studies on the ecological risk assessment and management of pollutant chemicals
- 23169 : Development of methodologies for the identification of chemicals by global analysis using the chromatograph mass spectrometry
- 23241 : The Study about a New Evaluation System of the Ecological Effect with Chemicals.
- 23242 : The reinforcement as the standard organization about the examination for ecological effect (Reference Laboratory)
- 23246 : Fundamental research for risk assessment of chemicals
- 23247 : Toxicity evaluation for effective effluent management and development of toxicity reduction methods
Fiscal Year: 2014
- 22588 : Studies on the ecological risk assessment and management of pollutant chemicals
- 22818 : Development of methodologies for the identification of chemicals by global analysis using the chromatograph mass spectrometry
- 22836 : The reinforcement as the standard organization about the examination for ecological effect (Reference Laboratory)
- 22902 : Development of test methods for endocrine disrupting chemicals in 2014
- 22903 : Investigation on water environment management method using biological responses
- 22904 : Development of eco-toxicity tests for environmental assessment of pharmaceuticals
- 22905 : Toxicity evaluation for effective effluent management and development of toxicity reduction methods
- 22906 : Development of sediment toxicity test using amphipods and investigation of sediment risk asessment
- 22930 : Fundamental research for risk assessment of chemicals
Fiscal Year: 2013
- 22172 : Studies on the ecological risk assessment and management of pollutant chemicals
- 22364 : The reinforcement as the standard organization about the examination for ecological effect (Reference Laboratory)
- 22409 : Development of methodologies for the identification of chemicals by global analysis using the chromatograph mass spectrometry
- 22479 : Mixture toxicity of multiple herbicides present in commercial herbicide products
- 22484 : Fundamental research for risk assessment of chemicals
- 22487 : Development of eco-toxicity tests for environmental assessment of pharmaceuticals
- 22563 : Development of test methods for endocrine disrupting chemicals in 2013
- 22564 : Investigation on water environment management method using biological responses
Fiscal Year: 2012
- 21743 : Studies on the ecological risk assessment and management of pollutant chemicals
- 22085 : The reinforcement as the standard organization about the examination for ecological effect (Reference Laboratory)
- 22086 : Investigation of current effects of pesticides on aquatic organisms in 2012
- 22087 : Development of test methods for endocrine disrupting chemicals in 2012
- 22088 : Investigation on water environment management method using biological responses
Fiscal Year: 2011
- 21300 : Studies on the ecological risk assessment and management of pollutant chemicals
- 21356 : Study for guideline drawing up of the environmental assessment of the pharmaceutical.
- 21472 : Investigation of the effect that pesticide gives to an aquatic organism in nature in 2011
- 21528 : Development practice of the test method for endocrine disruption chemicals in 2011
- 21541 : Study/investigation of the aqueous environment control procedure by the WET program
- 21690 : Acute toxicity to aquatic organisms of nonylphenol ethoxylates

View all

Research Result (Publication)

all
Original Paper
Review
Other Publications

Original Paper
Ecotoxicity assessment of phthalic acid di-alkyl ester mixtures toward aquatic organisms based on results from a series of subchronic toxicity tests

Presenter : Oda Y., Kawano M., Watanabe H., Yamagishi T., Yamamoto H.
Title : , Environmental Toxicology and Chemistry (2025)
Original Paper
Relative gene expression analysis of catalase in environmental RNA from Japanese medaka exposed to toxic chemicals

Presenter : Hiki K., Watanabe H., Yamamoto H.
Title : , Environmental DNA, 6(2):e532 (2024)
Original Paper
Non-chemical stresses do not strongly induce male offspring in Daphnia magna ascertained using the short-term juvenile hormone activity screening assay

Presenter : Watanabe H., Abe R., Tatarazako N., Yamamoto H.
Title : , Journal of Applied Toxicology (2024)
Original Paper
Prediction of chronic toxicity of pharmaceuticals in Daphnia magna by combining ortholog prediction, pharmacological effects, and quantitative structure-activity relationship

Presenter : Ninomiya Y., Watanabe H., Yamagishi T., Maruyama-Komoda T., Yamada T., Yamamoto H.
Title : , Ecotoxicology and Environmental Safety, 282(116737): (2024)
Original Paper
Developing a Passive Dosing Method for Acute Aquatic Toxicity Tests of Cationic Surfactant Benzalkoniums (BACs)

Presenter : Do T., Hiki K., Watanabe H., Yamamoto H., Endo S.
Title : , Environmental Science & Technology, 58(31):13678-13686 (2024)
Original Paper
Freely dissolved concentration profile and Hyalella azteca toxicity of cationic surfactant C12-benzalkonium in spiked-sediment toxicity test

Presenter : Yoshii S., Hiki K., Watanabe H., Yamamoto H., Endo S.
Title : , Science of the Total Environment, 866:161226 (2023)
Original Paper
Influence of water exchange rates on toxicity and bioaccumulation of hydrophobic organic chemicals in sediment toxicity tests

Presenter : Hiki K., Fischer F., Nishimori T., Endo S., Watanabe H., Yamamoto H.
Title : , Environmental Science: Processes & Impacts (2023)
Other Publications
The complete mitochondrial genome of water flea Ceriodaphnia dubia (Crustacea: Cladocera) NIES strain

Presenter : Hiki K., Oka K., Nakajima N., Watanabe H., Yamamoto H., Yamagishi T.
Title : , Mitochondrial DNA Part B: Resources, 8(8):831-835 (2023)
Review
Juvenile hormone synthesis and signaling disruption triggering male offspring induction and population decline in cladocerans (water flea): Review and adverse outcome pathway development

Presenter : Toyota K., Watanabe H., Hirano M., Abe R., Miyakawa H., Song Y., Sato T., Miyagawa S., Tollefsen K. E., Yamamoto H., Tatarazako N., Iguchi T.
Title : , Aquatic Toxicology, 243(106058): (2022)
Original Paper
Potential differences in chitin synthesis ability cause different sensitivities to diflubenzuron among three strains of Daphnia magna

Presenter : KATO K., Okamura K., Hiki K., Kintsu H., Nohara K., Yamagishi T., Nakajima N., Watanabe H., Yamamoto H.
Title : , Aquatic Toxicology, 243(106071): (2022)
Original Paper
Comparison of Species Sensitivity Distributions for Sediment-Associated Nonionic Organic Chemicals Through Equilibrium Partitioning Theory and Spiked-Sediment Toxicity Tests with Invertebrates

Presenter : Hiki K., Iwasaki Y., Watanabe H., Yamamoto H.
Title : , Environmental Toxicology and Chemistry, 41(412):462-473 (2022)
Original Paper
Severity classification of clinical signs and defining the moribund state as an experimental endpoint for acute toxicity testing using Japanese medaka (Oryzias latipes)

Presenter : Yamagishi T., Kawano M., Watanabe H., Yagi A., Shintaku Y., Ohno K., Yamamoto H.
Title : , Environmental Toxicology and Chemistry, 41(4):1089-1095 (2022)
Original Paper
Summary of 17 chemicals evaluated by OECD TG229 using Japanese Medaka, Oryzias latipes in EXTEND 2016

Presenter : Kawashima Y., Onishi Y., Tatarazako N., Yamamoto H., Koshio M., Oka T., Horie Y., Watanabe H., Nakamoto T., Yamamoto J., Ishikawa H., Sato T., Yamazaki K., Iguchi T.
Title : , Journal of Applied Toxicology, 42(7):750-777 (2022)
Original Paper
Comparing 10‐ and 28‐Day Sediment Toxicity and Bioaccumulation of Fluoranthene in Hyalella azteca Using Passive Sampling Techniques

Presenter : Nishimori T., Hiki K., Fischer F., Endo S., Yamamoto H., Watanabe H.
Title : , Environmental Toxicology and Chemistry (2022)
Original Paper
Spatiotemporal distribution of hydrophobic organic contaminants in spiked-sediment toxicity tests: Measuring total and freely dissolved concentrations in pore and overlying water

Presenter : Hiki K., Fischer F., Nishimori T., Watanabe H., Yamamoto H., Endo S.
Title : , Environmental Toxicology and Chemistry (2021)
Original Paper
Sources of variation in sediment toxicity of hydrophobic organic chemicals: Meta-analysis of 10-14-day spiked-sediment tests with Hyalella azteca and Chironomus dilutus

Presenter : Hiki K., Watanabe H., Yamamoto H.
Title : , Integrated Environmental Assessment and Management, 17(5):1003-1013 (2021)
Other Publications
Acute Toxicity of a Tire Rubber-Derived Chemical, 6PPD Quinone, to Freshwater Fish and Crustacean Species

Presenter : Hiki K., Asahina K., KATO K., Yamagishi T., Omagari R., Iwasaki Y., Watanabe H., Yamamoto H.
Title : , Environmental Science & Technology Letters, 8(9):779-784 (2021)
Original Paper
Toxicity assessment of typical polycyclic aromatic hydrocarbons to Daphnia magna and Hyalella azteca in water-only and sediment-water exposure systems

Presenter : Tani K., Watanabe H., Noguchi M., Hiki K., Yamagishi T., Yamamoto H.
Title : , Science of the Total Environment, 784(147156): (2021)
Original Paper
Summary of reference chemicals evaluated by the fish shortterm reproduction assay, OECD TG229, using Japanese Medaka, Oryzias latipes

Presenter : Onishi Y., Tatarazako N., Koshio M., Okamura T., Watanabe H., Sawai A., Yamamoto J., Ishikawa H., Sato T. , Kawashima Y., Yamazaki K., Iguchi T.
Title : , Journal of Applied Toxicology, 41(8):1201-1222 (2021)
Original Paper
Dying for change: A roadmap to refine the fish acute toxicity test after 40 years of applying a lethal endpoint

Presenter : Katsiadaki I., Ellis T., Andersen L., Antczak P., Burden N., Fisher T., Green C., Labram B., Pearson A., Peersen K., Pickford D., Ramsden C., Rønneseth A., Ryder K., SackerD., Stevens C., Watanabe H., Yamamoto H., Sewell F., Hawkins P., Rufli H., Hnady R.D., Maynard S. K., Jacobs M. N.
Title : , Ecotoxicology and Environmental Safety, 223(2021):112585 (2021)
Original Paper
Production of genome-edited Daphnia for heavy metal detection by fluorescence

Presenter : Arao T., Kato Y., Nong Q.D. , Yamamoto H., Watanabe H., Matsuura T., Tatarazako N., Tani K., Okamoto A., Matsumoto T., Watanabe H.
Title : , Scientific Reports, 10(21490):1-10 (2020)
Original Paper
Whole transcriptome analysis of an estuarine amphipod exposed to highway road dust

Presenter : Hiki K., Nakajima F., Tobino T., Watanabe H., Yamamoto H.
Title : , Science of the Total Enviroment, 675:141-150 (2019)
Original Paper
Comparison of the effects of constant and pulsed exposure with equivalent time-weighted average concentrations of the juvenile hormone analog pyriproxyfen on the reproduction of Daphnia magna

Presenter : Watanabe H., Oda S., Abe R., Tanaka Y., Tatarazako N.
Title : , Chemosphere, 195:810-816 (2018)
Original Paper
De novo transcriptome sequencing of an estuarine amphipod Grandidierella japonica exposed to zinc. Marine Genomics

Presenter : Hiki K., Watanabe H., Nakajima F., Nakajima N., Tobino T.
Title : , Marine Genomics (2018)
Original Paper
Estimation of population-level effect of the endocrine disruptor pyriproxyfen in Daphnia magna by using changes in sex ratio and reproductive output

Presenter : Tanaka Y., Nakamura K., Oda S., Watanabe H., Tatarazako N.
Title : , Ecotoxicology and Environmental Safety, 156:463-475 (2018)
Original Paper
Validation of a two-generational reproduction test in Daphnia magna: An interlaboratory exercise

Presenter : Barata C. , Campos B., Rivetti C., LeBlanc G.A., Eytcheson S., McKnight S., Tobor-Kaplon M., de Vries Buitenweg S., Choi S., Choi J., Sarapultseva E.I., Coutellec M.A., Coke M., Pandard P., Chaumot A., Queau H., Delorme N., Geffard O., Martinez-Jeronimo F., Watanabe H., Tatarazako N., Lopes I., Pestana J.L.T., Soares A.M.V.M., Pereira C.M., De Schamphelaere K.
Title : , Science of the Total Environment, 579:1073-1083 (2017)
Original Paper
Medaka Extended One-Generation Reproduction Test (MEOGRT) evaluating 4-Nonylphenol

Presenter : Watanabe H., Horie Y., Takanobu H., Koshio M., Flynn K., Iguchi T. , Tatarazako N.
Title : , nvironmental Toxicology and Chemistry, 36(12):3254-3266 (2017)
Original Paper
Effects of triphenyltin on reproduction in Japanese medaka (Oryzias latipes) across two generations

Presenter : Horie Y., Watanabe H., Takanobu H., Yamagishi T., Iguchi T., Tatarazako N.
Title : , Aquatic Toxicology, 192:16-23 (2017)
Original Paper
Chronic toxicity of an environmentally relevant mixture of pharmaceuticals to three aquatic organisms (alga, daphnid, and fish)

Presenter : Watanabe H., Tamura I., Abe R., Takanobu H., Nakamura A., Suzuki T., Hirose A., Nishimura T., Tatarazako N.
Title : , Environmental Toxicology and Chemistry, 35(4):996-1006 (2016)
Original Paper
Development of an in vivo anti-androgenic activity detection assay using fenitrothion in Japanese medaka (Oryzias latipes).

Presenter : Horie Y., Watanabe H., Takanobu H, Yagi A., Yamagishi T., Iguchi T, Tatarazako N.
Title : , Journal of Applied Toxicology (2016)
Original Paper
Diofenolan induces male offspring production through binding to the juvenile hormone receptor in Daphnia magna

Presenter : Abe R., Toyota K, Miyakawa H, Watanabe H., Oka T, Miyagawa S, Nishide H, Uchiyama I, Tollefsen K E, Iguchi T, Tatarazako N.
Title : , Aquatic Toxicology, 159:44-51 (2015)
Original Paper
Increasing Scientific Confidence in Adverse Outcome Pathways: Application of Tailored Bradford-Hill Considerations for Evaluating Weight of Evidence

Presenter : Becker R. A., Ankley G. T., Edwards S.W., Kennedy S.W., Linkov I, Meek B., Sachana M., Segner H., Van Der Burg B., Villeneuve D.L., Watanabe H., Barton-Maclaren T.S.
Title : , Regulatory Toxicology and Pharmacology, 72:514-537 (2015)
Original Paper
Towards modelling of the environmental fate of pharmaceuticals using the QSPR-MM scheme

Presenter : Jagiello K., Mostrag-Szlichtyng A., Gajewicz A., Kawai T., Imaizumi Y., Sakurai T., Yamamoto H., Tatarazako N., Mizukawa K., Aoki Y., Suzuki N., Watanabe H., Puzyn T.
Title : , Environmental Modelling & Software, 72:147-154 (2015)
Original Paper
Bioconcentration of perfluorinated compounds in wild medaka is related to octanol/water partition coefficient

Presenter : Iwabuchi K., Senzaki N., Tsuda S., Watanabe H., Tamura I., Takanobu H., Tatarazako N.
Title : , Fundamental Toxicological Sciences, 2(5):201-208 (2015)
Original Paper
Reductionin toxicity of coking wastewater to aquatic organisms by vertical tubular biological reactor

Presenter : Zhou S., Watanabe H., Wei C., Zhou J., Tatarazako N., Masungawa S., Zhang Y.
Title : , Ecotoxicology and Environmental Safety, 115:217-222 (2015)
Original Paper
Establishment of a short-term, in vivo screening method for detecting chemicals with juvenile hormone activity using adult Daphnia magna

Presenter : Abe R., Watanabe H., Yamamuro M., Iguchi T., Tatarazako N.
Title : , Journal of Applied Toxicology (2014)
Original Paper
Application of whole sediment toxicity identification evaluation procedures to road dust using a benthic ostracod Heterocypris incongruens

Presenter : Watanabe H. , Nakajima F., Kasuga I., Furumai H.
Title : , Ecotoxicology and Environmental Safety, 89:245-251 (2013)
Original Paper
Toxicity evaluation of road dust in the runoff process using a benthic ostracod Heterocypris incongruens

Presenter : Watanabe H. , Nakajima F., Kasuga I., Furumai H.
Title : , Science of the Total Environment, 409:2366-2372 (2011)

View all

Ecotoxicity assessment of phthalic acid di-alkyl ester mixtures toward aquatic organisms based on results from a series of subchronic toxicity tests

Presenter : Oda Y., Kawano M., Watanabe H., Yamagishi T., Yamamoto H.
Title : , Environmental Toxicology and Chemistry (2025)
Relative gene expression analysis of catalase in environmental RNA from Japanese medaka exposed to toxic chemicals

Presenter : Hiki K., Watanabe H., Yamamoto H.
Title : , Environmental DNA, 6(2):e532 (2024)
Non-chemical stresses do not strongly induce male offspring in Daphnia magna ascertained using the short-term juvenile hormone activity screening assay

Presenter : Watanabe H., Abe R., Tatarazako N., Yamamoto H.
Title : , Journal of Applied Toxicology (2024)
Prediction of chronic toxicity of pharmaceuticals in Daphnia magna by combining ortholog prediction, pharmacological effects, and quantitative structure-activity relationship

Presenter : Ninomiya Y., Watanabe H., Yamagishi T., Maruyama-Komoda T., Yamada T., Yamamoto H.
Title : , Ecotoxicology and Environmental Safety, 282(116737): (2024)
Developing a Passive Dosing Method for Acute Aquatic Toxicity Tests of Cationic Surfactant Benzalkoniums (BACs)

Presenter : Do T., Hiki K., Watanabe H., Yamamoto H., Endo S.
Title : , Environmental Science & Technology, 58(31):13678-13686 (2024)
Freely dissolved concentration profile and Hyalella azteca toxicity of cationic surfactant C12-benzalkonium in spiked-sediment toxicity test

Presenter : Yoshii S., Hiki K., Watanabe H., Yamamoto H., Endo S.
Title : , Science of the Total Environment, 866:161226 (2023)
Influence of water exchange rates on toxicity and bioaccumulation of hydrophobic organic chemicals in sediment toxicity tests

Presenter : Hiki K., Fischer F., Nishimori T., Endo S., Watanabe H., Yamamoto H.
Title : , Environmental Science: Processes & Impacts (2023)
Potential differences in chitin synthesis ability cause different sensitivities to diflubenzuron among three strains of Daphnia magna

Presenter : KATO K., Okamura K., Hiki K., Kintsu H., Nohara K., Yamagishi T., Nakajima N., Watanabe H., Yamamoto H.
Title : , Aquatic Toxicology, 243(106071): (2022)
Comparison of Species Sensitivity Distributions for Sediment-Associated Nonionic Organic Chemicals Through Equilibrium Partitioning Theory and Spiked-Sediment Toxicity Tests with Invertebrates

Presenter : Hiki K., Iwasaki Y., Watanabe H., Yamamoto H.
Title : , Environmental Toxicology and Chemistry, 41(412):462-473 (2022)
Severity classification of clinical signs and defining the moribund state as an experimental endpoint for acute toxicity testing using Japanese medaka (Oryzias latipes)

Presenter : Yamagishi T., Kawano M., Watanabe H., Yagi A., Shintaku Y., Ohno K., Yamamoto H.
Title : , Environmental Toxicology and Chemistry, 41(4):1089-1095 (2022)
Summary of 17 chemicals evaluated by OECD TG229 using Japanese Medaka, Oryzias latipes in EXTEND 2016

Presenter : Kawashima Y., Onishi Y., Tatarazako N., Yamamoto H., Koshio M., Oka T., Horie Y., Watanabe H., Nakamoto T., Yamamoto J., Ishikawa H., Sato T., Yamazaki K., Iguchi T.
Title : , Journal of Applied Toxicology, 42(7):750-777 (2022)
Comparing 10‐ and 28‐Day Sediment Toxicity and Bioaccumulation of Fluoranthene in Hyalella azteca Using Passive Sampling Techniques

Presenter : Nishimori T., Hiki K., Fischer F., Endo S., Yamamoto H., Watanabe H.
Title : , Environmental Toxicology and Chemistry (2022)
Spatiotemporal distribution of hydrophobic organic contaminants in spiked-sediment toxicity tests: Measuring total and freely dissolved concentrations in pore and overlying water

Presenter : Hiki K., Fischer F., Nishimori T., Watanabe H., Yamamoto H., Endo S.
Title : , Environmental Toxicology and Chemistry (2021)
Sources of variation in sediment toxicity of hydrophobic organic chemicals: Meta-analysis of 10-14-day spiked-sediment tests with Hyalella azteca and Chironomus dilutus

Presenter : Hiki K., Watanabe H., Yamamoto H.
Title : , Integrated Environmental Assessment and Management, 17(5):1003-1013 (2021)
Toxicity assessment of typical polycyclic aromatic hydrocarbons to Daphnia magna and Hyalella azteca in water-only and sediment-water exposure systems

Presenter : Tani K., Watanabe H., Noguchi M., Hiki K., Yamagishi T., Yamamoto H.
Title : , Science of the Total Environment, 784(147156): (2021)
Summary of reference chemicals evaluated by the fish shortterm reproduction assay, OECD TG229, using Japanese Medaka, Oryzias latipes

Presenter : Onishi Y., Tatarazako N., Koshio M., Okamura T., Watanabe H., Sawai A., Yamamoto J., Ishikawa H., Sato T. , Kawashima Y., Yamazaki K., Iguchi T.
Title : , Journal of Applied Toxicology, 41(8):1201-1222 (2021)
Dying for change: A roadmap to refine the fish acute toxicity test after 40 years of applying a lethal endpoint

Presenter : Katsiadaki I., Ellis T., Andersen L., Antczak P., Burden N., Fisher T., Green C., Labram B., Pearson A., Peersen K., Pickford D., Ramsden C., Rønneseth A., Ryder K., SackerD., Stevens C., Watanabe H., Yamamoto H., Sewell F., Hawkins P., Rufli H., Hnady R.D., Maynard S. K., Jacobs M. N.
Title : , Ecotoxicology and Environmental Safety, 223(2021):112585 (2021)
Production of genome-edited Daphnia for heavy metal detection by fluorescence

Presenter : Arao T., Kato Y., Nong Q.D. , Yamamoto H., Watanabe H., Matsuura T., Tatarazako N., Tani K., Okamoto A., Matsumoto T., Watanabe H.
Title : , Scientific Reports, 10(21490):1-10 (2020)
Whole transcriptome analysis of an estuarine amphipod exposed to highway road dust

Presenter : Hiki K., Nakajima F., Tobino T., Watanabe H., Yamamoto H.
Title : , Science of the Total Enviroment, 675:141-150 (2019)
Comparison of the effects of constant and pulsed exposure with equivalent time-weighted average concentrations of the juvenile hormone analog pyriproxyfen on the reproduction of Daphnia magna

Presenter : Watanabe H., Oda S., Abe R., Tanaka Y., Tatarazako N.
Title : , Chemosphere, 195:810-816 (2018)
De novo transcriptome sequencing of an estuarine amphipod Grandidierella japonica exposed to zinc. Marine Genomics

Presenter : Hiki K., Watanabe H., Nakajima F., Nakajima N., Tobino T.
Title : , Marine Genomics (2018)
Estimation of population-level effect of the endocrine disruptor pyriproxyfen in Daphnia magna by using changes in sex ratio and reproductive output

Presenter : Tanaka Y., Nakamura K., Oda S., Watanabe H., Tatarazako N.
Title : , Ecotoxicology and Environmental Safety, 156:463-475 (2018)
Validation of a two-generational reproduction test in Daphnia magna: An interlaboratory exercise

Presenter : Barata C. , Campos B., Rivetti C., LeBlanc G.A., Eytcheson S., McKnight S., Tobor-Kaplon M., de Vries Buitenweg S., Choi S., Choi J., Sarapultseva E.I., Coutellec M.A., Coke M., Pandard P., Chaumot A., Queau H., Delorme N., Geffard O., Martinez-Jeronimo F., Watanabe H., Tatarazako N., Lopes I., Pestana J.L.T., Soares A.M.V.M., Pereira C.M., De Schamphelaere K.
Title : , Science of the Total Environment, 579:1073-1083 (2017)
Medaka Extended One-Generation Reproduction Test (MEOGRT) evaluating 4-Nonylphenol

Presenter : Watanabe H., Horie Y., Takanobu H., Koshio M., Flynn K., Iguchi T. , Tatarazako N.
Title : , nvironmental Toxicology and Chemistry, 36(12):3254-3266 (2017)
Effects of triphenyltin on reproduction in Japanese medaka (Oryzias latipes) across two generations

Presenter : Horie Y., Watanabe H., Takanobu H., Yamagishi T., Iguchi T., Tatarazako N.
Title : , Aquatic Toxicology, 192:16-23 (2017)
Chronic toxicity of an environmentally relevant mixture of pharmaceuticals to three aquatic organisms (alga, daphnid, and fish)

Presenter : Watanabe H., Tamura I., Abe R., Takanobu H., Nakamura A., Suzuki T., Hirose A., Nishimura T., Tatarazako N.
Title : , Environmental Toxicology and Chemistry, 35(4):996-1006 (2016)
Development of an in vivo anti-androgenic activity detection assay using fenitrothion in Japanese medaka (Oryzias latipes).

Presenter : Horie Y., Watanabe H., Takanobu H, Yagi A., Yamagishi T., Iguchi T, Tatarazako N.
Title : , Journal of Applied Toxicology (2016)
Diofenolan induces male offspring production through binding to the juvenile hormone receptor in Daphnia magna

Presenter : Abe R., Toyota K, Miyakawa H, Watanabe H., Oka T, Miyagawa S, Nishide H, Uchiyama I, Tollefsen K E, Iguchi T, Tatarazako N.
Title : , Aquatic Toxicology, 159:44-51 (2015)
Increasing Scientific Confidence in Adverse Outcome Pathways: Application of Tailored Bradford-Hill Considerations for Evaluating Weight of Evidence

Presenter : Becker R. A., Ankley G. T., Edwards S.W., Kennedy S.W., Linkov I, Meek B., Sachana M., Segner H., Van Der Burg B., Villeneuve D.L., Watanabe H., Barton-Maclaren T.S.
Title : , Regulatory Toxicology and Pharmacology, 72:514-537 (2015)
Towards modelling of the environmental fate of pharmaceuticals using the QSPR-MM scheme

Presenter : Jagiello K., Mostrag-Szlichtyng A., Gajewicz A., Kawai T., Imaizumi Y., Sakurai T., Yamamoto H., Tatarazako N., Mizukawa K., Aoki Y., Suzuki N., Watanabe H., Puzyn T.
Title : , Environmental Modelling & Software, 72:147-154 (2015)
Bioconcentration of perfluorinated compounds in wild medaka is related to octanol/water partition coefficient

Presenter : Iwabuchi K., Senzaki N., Tsuda S., Watanabe H., Tamura I., Takanobu H., Tatarazako N.
Title : , Fundamental Toxicological Sciences, 2(5):201-208 (2015)
Reductionin toxicity of coking wastewater to aquatic organisms by vertical tubular biological reactor

Presenter : Zhou S., Watanabe H., Wei C., Zhou J., Tatarazako N., Masungawa S., Zhang Y.
Title : , Ecotoxicology and Environmental Safety, 115:217-222 (2015)
Establishment of a short-term, in vivo screening method for detecting chemicals with juvenile hormone activity using adult Daphnia magna

Presenter : Abe R., Watanabe H., Yamamuro M., Iguchi T., Tatarazako N.
Title : , Journal of Applied Toxicology (2014)
Application of whole sediment toxicity identification evaluation procedures to road dust using a benthic ostracod Heterocypris incongruens

Presenter : Watanabe H. , Nakajima F., Kasuga I., Furumai H.
Title : , Ecotoxicology and Environmental Safety, 89:245-251 (2013)
Toxicity evaluation of road dust in the runoff process using a benthic ostracod Heterocypris incongruens

Presenter : Watanabe H. , Nakajima F., Kasuga I., Furumai H.
Title : , Science of the Total Environment, 409:2366-2372 (2011)

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Juvenile hormone synthesis and signaling disruption triggering male offspring induction and population decline in cladocerans (water flea): Review and adverse outcome pathway development

Presenter : Toyota K., Watanabe H., Hirano M., Abe R., Miyakawa H., Song Y., Sato T., Miyagawa S., Tollefsen K. E., Yamamoto H., Tatarazako N., Iguchi T.
Title : , Aquatic Toxicology, 243(106058): (2022)

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The complete mitochondrial genome of water flea Ceriodaphnia dubia (Crustacea: Cladocera) NIES strain

Presenter : Hiki K., Oka K., Nakajima N., Watanabe H., Yamamoto H., Yamagishi T.
Title : , Mitochondrial DNA Part B: Resources, 8(8):831-835 (2023)
Acute Toxicity of a Tire Rubber-Derived Chemical, 6PPD Quinone, to Freshwater Fish and Crustacean Species

Presenter : Hiki K., Asahina K., KATO K., Yamagishi T., Omagari R., Iwasaki Y., Watanabe H., Yamamoto H.
Title : , Environmental Science & Technology Letters, 8(9):779-784 (2021)

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Research Result (Presentation)

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Research Presentation

Research Presentation
Concentration profiles of organic chemicals across sediment-water interface: Experimental and modeling approaches in spiked-sediment toxicity tests

Presenter : Hiki K., Fischer F., Nishimori T., Yoshii S., Watanabe H., Endo S., Yamamoto H.
Name of Society : SETAC Asia-Pacific 14th Biennial Meeting (2024)
Name of Proceedings : Abstracts
Research Presentation
Mixture effects of dialkylesters of phthalic acids (PAEs) on aquatic organisms based on predicted environmental exposure profiles

Presenter : Oda Y., Imaizumi Y., Watanabe H., Hiki K., Yamagishi T., Yamamoto H.
Name of Society : 21st International Symposium on Toxicity Assessment (ISTA21) (2024)
Name of Proceedings : -
Research Presentation
How much known chemical substances in receiving water can explain the measured toxicity to alga, daphnid and fish?

Presenter : Watanabe H., Nakajima D., Yamagishi T., Yamamoto H.
Name of Society : 21st International Symposium on Toxicity Assessment (ISTA21) (2024)
Name of Proceedings : Abstracts, 70
Research Presentation
A novel approach for categorizing mode of action of chemicals by utilizing time-to-death observed in the fish acute toxicity test

Presenter : Huang R., Yamagishi T., Hiki K., Ohno K., Watanabe H., Yamamoto H.
Name of Society : 3rd Joint Concerence on Environmental Chemicals (2024)
Name of Proceedings : Abstract
Research Presentation
Ecological risk assessment of human pharmaceuticals detected in Japan and establishment of ecotoxicity database

Presenter : Yamamoto H., Ninomiya Y., Watanabe H., Yamagishi T., Kobayashi N., Ikarashi Y., Yamada, Hirose A.
Name of Society : SETAC Europe 34th Annual Meeting (2024)
Name of Proceedings : Abstracts
Research Presentation
Toward the Tier Two Environmental Risk Assessment of Groups of Chemicals: A Case Study on Sulfa Drugs

Presenter : Ozawa F., Watanabe H., Yamagishi T., Sato R., Maichi S., Yamamoto H., Ohno K.
Name of Society : SETAC Europe 34th Annual Meeting (2024)
Name of Proceedings : Abstracts
Research Presentation
Assessing the applicability domain of fish embryo toxicity test as alternatives of fish acute toxicity test, utilizing time-to-death in FET test

Presenter : Huang R., Yamagishi T., Watanabe H., Ohno K., Yamamoto H.
Name of Society : SETAC Europe 34th Annual Meeting (2024)
Name of Proceedings : Abstracts
Research Presentation
Innovative ecological impact assessment using life-table response experiments and interstage flow matrices: Ecotoxicity of phthalate esters with different alkyl chain length

Presenter : Yokomizo H., Tsuzuki Y., Kamo M., Takada T., Oda Y., Watanabe H., Yamamoto H.
Name of Society : The Joint Meeting of the Annual Meeting of the Society of Population Ecology and Taiwan-Japan Ecology Workshop 2024 (2024)
Name of Proceedings : Abstracts, 58-59
Research Presentation
Characterization of Structural Similarity and Mode of Action of Chemicals with High Reproductive Toxicity to Daphnia magna

Presenter : Watanabe H., Itami Y., Ninomiya Y., Sugiura T., Yamamoto H., Ohno K.
Name of Society : SETAC North America 45th Annual Meeting (2024)
Name of Proceedings : Abstracts, 348
Research Presentation
Development of Short-Term Screening Assay System for Detecting Anti-Juvenile Hormone (JH) Activity: JH Receptor Antagonists and JH Biosynthesis Inhibitor

Presenter : Oda Y., Watanabe H., Takahata Y., Miyakawa H., Yamamoto H.
Name of Society : SETAC North America 45th Annual Meeting (2024)
Name of Proceedings : Abstracts, 78
Research Presentation
Evaluation of the Mode of Action (MoA) of Chemicals Based on Time-to- Death Data Obtained from Fish Embryo Acute Toxicity (FET) Test

Presenter : Huang R., Yamagishi T., Watanabe H., Hiki K., Ohno K., Yamamoto H.
Name of Society : SETAC North America 45th Annual Meeting (2024)
Name of Proceedings : Abstracts, 160
Research Presentation
Identification of causative toxicants in river waters using bioassays with alga and daphnid and multiple-component chemical analysis

Presenter : Watanabe H., Yamagishi T., Omagari R., Nakajima D., Yamamoto H.
Name of Society : SETAC North America 44th Annual Meeting (2023)
Name of Proceedings : Abstracts, 20
Research Presentation
New OECD Test Guideline Proposal for Sediment-Water Amphipod Toxicity Test

Presenter : Hiki K., Watanabe H., Yamamoto H., Pandard P.
Name of Society : SETAC North America 44th Annual Meeting (2023)
Name of Proceedings : Abstracts, 97
Research Presentation
Mixture Effects of Phthalate Esters and Their Subgrouping Based on Toxicity Profiles

Presenter : Yamamoto H., Oda Y., Watanabe H., Yamagishi T., Hiki K., Ozawa F., Ohno K.
Name of Society : SETAC North America 44th Annual Meeting (2023)
Name of Proceedings : Abstracts, 117
Research Presentation
Ecotoxicity characterization of pharmaceuticals in relation to physiological responses of algae for sufficiently conservative environmental risk assessment using in silico tools

Presenter : Ninomya Y., Watanabe H., Yamagishi T., Yamamoto H.
Name of Society : SETAC Asia-Pacific 2022 Virtual Meeting (2022)
Name of Proceedings : -
Research Presentation
Passive sampling method for quantifying amphipod exposure to cationic surfactant in sediment toxicity test

Presenter : Yoshii S., Hiki K., Watanabe H., Endo S.
Name of Society : 13th International Passive Sampling Workshop and Symposium (2022)
Name of Proceedings : Book of Abstracts, 42
Research Presentation
Freely Dissolved Concentration Analysis of Cationic Surfactant Benzalkonium in Sediment Toxicity Test Using Passive Sampling Method

Presenter : Yoshii S., Hiki K., Watanabe H., Endo S.
Name of Society : SETAC Europe 32nd Annual Meeting (2022)
Name of Proceedings : Abstracts, 221-222
Research Presentation
Effect of Water Exchange Rate in Spiked-Sediment Toxicity Tests With Hyalella azteca on Behavior and Bioaccumulation of Hydrophobic Organic Chemicals

Presenter : Hiki K., Fischer F., Nishimori T., Endo S., Watanabe H., Yamamoto H.
Name of Society : SETAC Europe 32nd Annual Meeting (2022)
Name of Proceedings : Abstracts, 128
Research Presentation
Sensitivity Response Changes of Microbe-Associated Daphnia magna under Organophosphate Stress

Presenter : Villegas V., Yamagishi T., Watanabe H., Yamamoto H.
Name of Society : The 56th Annual Conference of Japan Society on Water Environment (2022)
Name of Proceedings : Proceeding of the 56th Annual Conference of Japan Society on Water Environment, 333
Research Presentation
Comparison of headspace and conventional passive dosing techniques to prepare aquatic solution of selected semi-volatile and highly volatile organic chemicals for aquatic toxicity tests with D. magna

Presenter : Lu Y., Yamagishi T., Watanabe H., Yamamoto H.
Name of Society : The 56th Annual Conference of Japan Society on Water Environment 2022 (2022)
Name of Proceedings : Proceeding of the 56th Annual Conference of Japan Society on Water Environment 2022, 332
Research Presentation
Development and assessment of Adverse Outcome Pathways for juvenile hormone mediated effects of environmental stimuli and chemicals in cladoceran

Presenter : Watanabe H., Toyota K., Hirano M., Abe R., Miyakawa H., Song Y., Tollefsen K.E., Yamamoto H., Iguchi T.
Name of Society : SETAC North America 43rd Annual Meeting (2022)
Name of Proceedings : Abstracts, 46
Research Presentation
Various clinical signs of Japanese medaka (Oryzias latipes) in fish acute toxicity test and their link with moribundity and death

Presenter : Yamagishi T., Watanabe H., Yamamoto H.
Name of Society : SETAC North America 43rd Annual Meeting (2022)
Name of Proceedings : Abstracts, 215
Research Presentation
Recent trend in OECD fish tests for chemical management and the test method development in NIES

Presenter : Yamamoto H., Watanabe H., Yamagishi T.
Name of Society : 第27回小型魚類研究会 (2021)
Name of Proceedings : The 27th Japanese Medaka and Zebrafish Meeting, 39
Research Presentation
Does the Pore Water Free Concentration Explain Everything in Sediment Contact Assays with Hydrophobic Organic Chemicals?

Presenter : Endo S., Hiki K., Fischer F., Watanabe H., Yamamoto H., Nakajima F.
Name of Society : SETAC North America 41st Annual Meeting (SciCon2) (2020)
Name of Proceedings : Abstract book, 317
Research Presentation
Short-term chronic toxicity of acrylic acid and acrylates esters to alga, daphnid and fish

Presenter : Watanabe H., Kawano M., Yamagishi T., Ozawa F., Ohno K., Yamamoto H.
Name of Society : SETAC North America 41st Annual Meeting (2020)
Name of Proceedings : Abstracts, 142
Research Presentation
RNA Seq analysis of estuarine amphipods exposed to highway road dust

Presenter : Hiki K., Nakajima F., Tobino T., Watanabe H., Yamamoto H.
Name of Society : SETAC Europe 29th Annual Meeting (2019)
Name of Proceedings : Abstracts, 444
Research Presentation
Validation of the protocol of juvenile hormone activity screening assay (JHASA) proposed to OECD

Presenter : Abe R., Watanabe H., Ogawa M., Adachi R., Okamura T., Matsumoto T., Okamoto A., Tatarazako N., Yamamoto H.
Name of Society : SETAC Europe 29th Annual Meeting (2019)
Name of Proceedings : Abstracts
Research Presentation
Case Studies of Toxicity Reduction Evaluation/Toxicity Identification Evaluation on Industrial Effluent in Japan

Presenter : Watanabe H., Yamagishi T., Abe R., Tatarazako N., Yamamoto H.
Name of Society : IWA World Water Congress and Exhibition 2018 (2018)
Name of Proceedings : -
Research Presentation
Chronic toxicity assessment of Ni contaminated rivers in Japan using Ceriodaphnia dubia for development of biotic ligand model for Japanese surface waters

Presenter : Watanabe H., Noguchi M., Misaki T., Oda S., Matsuzaki K., Yamamoto H.
Name of Society : SETAC Europe 28th Annual Meeting (2018)
Name of Proceedings : Abstracts, 313
Research Presentation
Effects of physico-chemical characteristics of formulated sediment on the survival and growth of amphipods Grandidierella japonica and Hyalella azteca

Presenter : Hiki K., Watanabe H., Yamamoto H., Nakajima F., Tobino T.
Name of Society : SETAC North America 39th Annual Meeting (2018)
Name of Proceedings : Abstracts, 261
Research Presentation
Can fish embryo toxicity (FET) test with three-spined stickleback (Gasterosteus aculeatus) show the similar transcriptional response demonstrated in acute toxicity test

Presenter : Watanabe H., Bean T., Sebrie M., Antczak P, Williams T.D., Hartnell D., Maisano M., Katsiadaki I.
Name of Society : SETAC EUROPE 25rd Annual Meeting (2015)
Name of Proceedings : Abstracts, 424
Research Presentation
Establishment of a short-term, in vivo screening method for detecting chemicals with juvenile hormone activity using adult Daphnia magna

Presenter : Abe R., Watanabe H., Iguchi T, Tatarazako N.
Name of Society : 10th International Conference on Juvenile Hormones (JHX) (2014)
Name of Proceedings : Abstracts
Research Presentation
Predictability of mixture toxicity of pharmaceuticals at environmental relevant concentration to three aquatic organisms

Presenter : Watanabe H., Tamura I., Abe R., Takanobu H., Nakamura A., Suzuki T., Hirose A., Nishimura T., Tatarazako N.
Name of Society : SETAC North America 35rd Annual Meeting (2014)
Name of Proceedings : SETAC North America 35rd Annual Meeting Abstract, 285
Research Presentation
Demographic risk estimation of endocrine disrupting chemicals based on effects to reproduction and sex of Daphnia- population simulation

Presenter : Tanaka Y., Watanabe H. , Tatarazako N.
Name of Society : SETAC Europe 23rd Annual Meeting (2013)
Name of Proceedings : Abstracts, 390 (TH128)
Research Presentation
Estimation of biological impact of surface water samples in Kasukawa River using algae, daphnids and fish

Presenter : Watanabe H., Yin W., Abe R., Takanobu H., Nakamura A., Yamamuro I., Tatarazako N.
Name of Society : SETAC EUROPE 23rd Annual Meeting (2013)
Name of Proceedings : Abstracts, 248
Research Presentation
Mixture toxicity of pharmaceuticals detected in treated municipal wastewater to three aquatic organisms (algae, daphnids and fish)

Presenter : Watanabe H., Abe R., Takanobu H., Nakamura A., Suzuki T., Hirose A., Nishimura T., Tatarazako N.
Name of Society : SETAC EUROPE 23rd Annual Meeting (2013)
Name of Proceedings : Abstracts, 248
Research Presentation
Verification of Fish Multi-Generation Test with the Estrone Using Japanese Medaka (Oryzias latipes)

Presenter : Tatarazako N., Nakamura A., Watanabe H., Tamura I., Takanobu H., Iguchi T.
Name of Society : SETAC North America 34th Annual Meeting (2013)
Name of Proceedings : Abstracts, 186
Research Presentation
Mixture toxicity of multiple herbicides present in commercial herbicide products in Japan

Presenter : Watanabe H., OGINO S., Tamura I., Takanobu H., Abe R., Koshio M., Tatarazako N.
Name of Society : Society of Environmental Toxicology and Chemistry North America 34th Annual Meeting (2013)
Name of Proceedings : Abstracts, 333
Research Presentation
Multi-generational effects of endocrine disrupting chemicals on Ceriodaphnia dubia

Presenter : Watanabe H. , Abe R., Oda S., Iguchi T., Tatarazako N.
Name of Society : SETAC Asia Pacific 2012 (2012)
Name of Proceedings : Abstracts, 78
Research Presentation
Efficacy of medaka TG229 in the screening of endocrine-disrupting chemicals

Presenter : Tatarazako N., Takanobu H. , Watanabe H. , Sawai Atsushi, Ohnishi Y., Nakamura A., Iguchi T.
Name of Society : SETAC Asia Pacific 2012 (2012)
Name of Proceedings : Abstracts, 179
Research Presentation
Application of Toxicity Identification Evaluation(TIE)procedures to industrial effluent using Ceriodaphnia dubia

Presenter : Yin W., Watanabe H. , Yamamuro M., Tatarazako N.
Name of Society : バイオアッセイ研究会・日本環境毒性学会第18回合同研究発表会 (2012)
Name of Proceedings : 同予稿集, 1-2
Research Presentation
The effects of nonylphenol ethoxylates having different ethylene oxide(EO)chain on fish, daphnia, and alga

Presenter : Tatarazako N., Oka T. , Watanabe H. , Takanobu H. , Abe R., Abe R., OGINO S., Shiraishi H.
Name of Society : 22th SETAC Eueope Annual Meeting/6th SETAC Europe Special Science Symposium (2012)
Name of Proceedings : Abstracts of 22th SETAC Eueope Annual Meeting/6th SETAC Europe Special Science Symposium, 131
Research Presentation
Evaluation of toxicities of herbicides using short-term chronic tests of alga, daphnid and fish

Presenter : Oka T. , Watanabe H. , Abe R., Koshio M., Takanobu H. , OGINO S., Iguchi T., Tatarazako N.
Name of Society : 22th SETAC Eueope Annual Meeting/6th SETAC Europe Special Science Symposium (2012)
Name of Proceedings : Abstracts of 22th SETAC Eueope Annual Meeting/6th SETAC Europe Special Science Symposium
, 228
Research Presentation
Toxicity assessment of road dust prepared under various elution conditions using a benthic ostracod

Presenter : Watanabe H. , Nakajima F., Kasuga I., Furumai H.
Name of Society : 12th International Conference on Urban Drainage (2011)
Name of Proceedings : Abstracts of 12th International Conference on Urban Drainage
Research Presentation
Assessment of urban road dust in Tokyo using whole sediment toxicity identification evaluation procedures

Presenter : Watanabe H. , Nakajima F., Tatarazako N., Kasuga I., Furumai H.
Name of Society : SETAC North America 32nd Annual Meeting (2011)
Name of Proceedings : Abstracts of SETAC North America 32nd Annual Meeting, 351
Research Presentation
Toxicity characterization of road dust using whole sediment toxicity identification evaluation procedures with a benthic ostracod

Presenter : Watanabe H. , Nakajima F., Kasuga I., Furumai H.
Name of Society : The 4th IWA-ASPIRE Conference and Exhibition (2011)
Name of Proceedings : Abstracts of The 4th IWA-ASPIRE Conference and Exhibition

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Concentration profiles of organic chemicals across sediment-water interface: Experimental and modeling approaches in spiked-sediment toxicity tests

Presenter : Hiki K., Fischer F., Nishimori T., Yoshii S., Watanabe H., Endo S., Yamamoto H.
Name of Society : SETAC Asia-Pacific 14th Biennial Meeting (2024)
Name of Proceedings : Abstracts
Mixture effects of dialkylesters of phthalic acids (PAEs) on aquatic organisms based on predicted environmental exposure profiles

Presenter : Oda Y., Imaizumi Y., Watanabe H., Hiki K., Yamagishi T., Yamamoto H.
Name of Society : 21st International Symposium on Toxicity Assessment (ISTA21) (2024)
Name of Proceedings : -
How much known chemical substances in receiving water can explain the measured toxicity to alga, daphnid and fish?

Presenter : Watanabe H., Nakajima D., Yamagishi T., Yamamoto H.
Name of Society : 21st International Symposium on Toxicity Assessment (ISTA21) (2024)
Name of Proceedings : Abstracts, 70
A novel approach for categorizing mode of action of chemicals by utilizing time-to-death observed in the fish acute toxicity test

Presenter : Huang R., Yamagishi T., Hiki K., Ohno K., Watanabe H., Yamamoto H.
Name of Society : 3rd Joint Concerence on Environmental Chemicals (2024)
Name of Proceedings : Abstract
Ecotoxicity characterization of pharmaceuticals in relation to physiological responses of algae for sufficiently conservative environmental risk assessment using in silico tools

Presenter : Ninomya Y., Watanabe H., Yamagishi T., Yamamoto H.
Name of Society : SETAC Asia-Pacific 2022 Virtual Meeting (2022)
Name of Proceedings : -
Passive sampling method for quantifying amphipod exposure to cationic surfactant in sediment toxicity test

Presenter : Yoshii S., Hiki K., Watanabe H., Endo S.
Name of Society : 13th International Passive Sampling Workshop and Symposium (2022)
Name of Proceedings : Book of Abstracts, 42
Effect of Water Exchange Rate in Spiked-Sediment Toxicity Tests With Hyalella azteca on Behavior and Bioaccumulation of Hydrophobic Organic Chemicals

Presenter : Hiki K., Fischer F., Nishimori T., Endo S., Watanabe H., Yamamoto H.
Name of Society : SETAC Europe 32nd Annual Meeting (2022)
Name of Proceedings : Abstracts, 128
Sensitivity Response Changes of Microbe-Associated Daphnia magna under Organophosphate Stress

Presenter : Villegas V., Yamagishi T., Watanabe H., Yamamoto H.
Name of Society : The 56th Annual Conference of Japan Society on Water Environment (2022)
Name of Proceedings : Proceeding of the 56th Annual Conference of Japan Society on Water Environment, 333
Comparison of headspace and conventional passive dosing techniques to prepare aquatic solution of selected semi-volatile and highly volatile organic chemicals for aquatic toxicity tests with D. magna

Presenter : Lu Y., Yamagishi T., Watanabe H., Yamamoto H.
Name of Society : The 56th Annual Conference of Japan Society on Water Environment 2022 (2022)
Name of Proceedings : Proceeding of the 56th Annual Conference of Japan Society on Water Environment 2022, 332
Recent trend in OECD fish tests for chemical management and the test method development in NIES

Presenter : Yamamoto H., Watanabe H., Yamagishi T.
Name of Society : 第27回小型魚類研究会 (2021)
Name of Proceedings : The 27th Japanese Medaka and Zebrafish Meeting, 39
Does the Pore Water Free Concentration Explain Everything in Sediment Contact Assays with Hydrophobic Organic Chemicals?

Presenter : Endo S., Hiki K., Fischer F., Watanabe H., Yamamoto H., Nakajima F.
Name of Society : SETAC North America 41st Annual Meeting (SciCon2) (2020)
Name of Proceedings : Abstract book, 317
Case Studies of Toxicity Reduction Evaluation/Toxicity Identification Evaluation on Industrial Effluent in Japan

Presenter : Watanabe H., Yamagishi T., Abe R., Tatarazako N., Yamamoto H.
Name of Society : IWA World Water Congress and Exhibition 2018 (2018)
Name of Proceedings : -
Multi-generational effects of endocrine disrupting chemicals on Ceriodaphnia dubia

Presenter : Watanabe H. , Abe R., Oda S., Iguchi T., Tatarazako N.
Name of Society : SETAC Asia Pacific 2012 (2012)
Name of Proceedings : Abstracts, 78
Application of Toxicity Identification Evaluation(TIE)procedures to industrial effluent using Ceriodaphnia dubia

Presenter : Yin W., Watanabe H. , Yamamuro M., Tatarazako N.
Name of Society : バイオアッセイ研究会・日本環境毒性学会第18回合同研究発表会 (2012)
Name of Proceedings : 同予稿集, 1-2
Toxicity assessment of road dust prepared under various elution conditions using a benthic ostracod

Presenter : Watanabe H. , Nakajima F., Kasuga I., Furumai H.
Name of Society : 12th International Conference on Urban Drainage (2011)
Name of Proceedings : Abstracts of 12th International Conference on Urban Drainage
Toxicity characterization of road dust using whole sediment toxicity identification evaluation procedures with a benthic ostracod

Presenter : Watanabe H. , Nakajima F., Kasuga I., Furumai H.
Name of Society : The 4th IWA-ASPIRE Conference and Exhibition (2011)
Name of Proceedings : Abstracts of The 4th IWA-ASPIRE Conference and Exhibition
Ecological risk assessment of human pharmaceuticals detected in Japan and establishment of ecotoxicity database

Presenter : Yamamoto H., Ninomiya Y., Watanabe H., Yamagishi T., Kobayashi N., Ikarashi Y., Yamada, Hirose A.
Name of Society : SETAC Europe 34th Annual Meeting (2024)
Name of Proceedings : Abstracts
Toward the Tier Two Environmental Risk Assessment of Groups of Chemicals: A Case Study on Sulfa Drugs

Presenter : Ozawa F., Watanabe H., Yamagishi T., Sato R., Maichi S., Yamamoto H., Ohno K.
Name of Society : SETAC Europe 34th Annual Meeting (2024)
Name of Proceedings : Abstracts
Assessing the applicability domain of fish embryo toxicity test as alternatives of fish acute toxicity test, utilizing time-to-death in FET test

Presenter : Huang R., Yamagishi T., Watanabe H., Ohno K., Yamamoto H.
Name of Society : SETAC Europe 34th Annual Meeting (2024)
Name of Proceedings : Abstracts
Innovative ecological impact assessment using life-table response experiments and interstage flow matrices: Ecotoxicity of phthalate esters with different alkyl chain length

Presenter : Yokomizo H., Tsuzuki Y., Kamo M., Takada T., Oda Y., Watanabe H., Yamamoto H.
Name of Society : The Joint Meeting of the Annual Meeting of the Society of Population Ecology and Taiwan-Japan Ecology Workshop 2024 (2024)
Name of Proceedings : Abstracts, 58-59
Characterization of Structural Similarity and Mode of Action of Chemicals with High Reproductive Toxicity to Daphnia magna

Presenter : Watanabe H., Itami Y., Ninomiya Y., Sugiura T., Yamamoto H., Ohno K.
Name of Society : SETAC North America 45th Annual Meeting (2024)
Name of Proceedings : Abstracts, 348
Development of Short-Term Screening Assay System for Detecting Anti-Juvenile Hormone (JH) Activity: JH Receptor Antagonists and JH Biosynthesis Inhibitor

Presenter : Oda Y., Watanabe H., Takahata Y., Miyakawa H., Yamamoto H.
Name of Society : SETAC North America 45th Annual Meeting (2024)
Name of Proceedings : Abstracts, 78
Evaluation of the Mode of Action (MoA) of Chemicals Based on Time-to- Death Data Obtained from Fish Embryo Acute Toxicity (FET) Test

Presenter : Huang R., Yamagishi T., Watanabe H., Hiki K., Ohno K., Yamamoto H.
Name of Society : SETAC North America 45th Annual Meeting (2024)
Name of Proceedings : Abstracts, 160
Identification of causative toxicants in river waters using bioassays with alga and daphnid and multiple-component chemical analysis

Presenter : Watanabe H., Yamagishi T., Omagari R., Nakajima D., Yamamoto H.
Name of Society : SETAC North America 44th Annual Meeting (2023)
Name of Proceedings : Abstracts, 20
New OECD Test Guideline Proposal for Sediment-Water Amphipod Toxicity Test

Presenter : Hiki K., Watanabe H., Yamamoto H., Pandard P.
Name of Society : SETAC North America 44th Annual Meeting (2023)
Name of Proceedings : Abstracts, 97
Mixture Effects of Phthalate Esters and Their Subgrouping Based on Toxicity Profiles

Presenter : Yamamoto H., Oda Y., Watanabe H., Yamagishi T., Hiki K., Ozawa F., Ohno K.
Name of Society : SETAC North America 44th Annual Meeting (2023)
Name of Proceedings : Abstracts, 117
Freely Dissolved Concentration Analysis of Cationic Surfactant Benzalkonium in Sediment Toxicity Test Using Passive Sampling Method

Presenter : Yoshii S., Hiki K., Watanabe H., Endo S.
Name of Society : SETAC Europe 32nd Annual Meeting (2022)
Name of Proceedings : Abstracts, 221-222
Development and assessment of Adverse Outcome Pathways for juvenile hormone mediated effects of environmental stimuli and chemicals in cladoceran

Presenter : Watanabe H., Toyota K., Hirano M., Abe R., Miyakawa H., Song Y., Tollefsen K.E., Yamamoto H., Iguchi T.
Name of Society : SETAC North America 43rd Annual Meeting (2022)
Name of Proceedings : Abstracts, 46
Various clinical signs of Japanese medaka (Oryzias latipes) in fish acute toxicity test and their link with moribundity and death

Presenter : Yamagishi T., Watanabe H., Yamamoto H.
Name of Society : SETAC North America 43rd Annual Meeting (2022)
Name of Proceedings : Abstracts, 215
Short-term chronic toxicity of acrylic acid and acrylates esters to alga, daphnid and fish

Presenter : Watanabe H., Kawano M., Yamagishi T., Ozawa F., Ohno K., Yamamoto H.
Name of Society : SETAC North America 41st Annual Meeting (2020)
Name of Proceedings : Abstracts, 142
RNA Seq analysis of estuarine amphipods exposed to highway road dust

Presenter : Hiki K., Nakajima F., Tobino T., Watanabe H., Yamamoto H.
Name of Society : SETAC Europe 29th Annual Meeting (2019)
Name of Proceedings : Abstracts, 444
Validation of the protocol of juvenile hormone activity screening assay (JHASA) proposed to OECD

Presenter : Abe R., Watanabe H., Ogawa M., Adachi R., Okamura T., Matsumoto T., Okamoto A., Tatarazako N., Yamamoto H.
Name of Society : SETAC Europe 29th Annual Meeting (2019)
Name of Proceedings : Abstracts
Chronic toxicity assessment of Ni contaminated rivers in Japan using Ceriodaphnia dubia for development of biotic ligand model for Japanese surface waters

Presenter : Watanabe H., Noguchi M., Misaki T., Oda S., Matsuzaki K., Yamamoto H.
Name of Society : SETAC Europe 28th Annual Meeting (2018)
Name of Proceedings : Abstracts, 313
Effects of physico-chemical characteristics of formulated sediment on the survival and growth of amphipods Grandidierella japonica and Hyalella azteca

Presenter : Hiki K., Watanabe H., Yamamoto H., Nakajima F., Tobino T.
Name of Society : SETAC North America 39th Annual Meeting (2018)
Name of Proceedings : Abstracts, 261
Can fish embryo toxicity (FET) test with three-spined stickleback (Gasterosteus aculeatus) show the similar transcriptional response demonstrated in acute toxicity test

Presenter : Watanabe H., Bean T., Sebrie M., Antczak P, Williams T.D., Hartnell D., Maisano M., Katsiadaki I.
Name of Society : SETAC EUROPE 25rd Annual Meeting (2015)
Name of Proceedings : Abstracts, 424
Establishment of a short-term, in vivo screening method for detecting chemicals with juvenile hormone activity using adult Daphnia magna

Presenter : Abe R., Watanabe H., Iguchi T, Tatarazako N.
Name of Society : 10th International Conference on Juvenile Hormones (JHX) (2014)
Name of Proceedings : Abstracts
Predictability of mixture toxicity of pharmaceuticals at environmental relevant concentration to three aquatic organisms

Presenter : Watanabe H., Tamura I., Abe R., Takanobu H., Nakamura A., Suzuki T., Hirose A., Nishimura T., Tatarazako N.
Name of Society : SETAC North America 35rd Annual Meeting (2014)
Name of Proceedings : SETAC North America 35rd Annual Meeting Abstract, 285
Demographic risk estimation of endocrine disrupting chemicals based on effects to reproduction and sex of Daphnia- population simulation

Presenter : Tanaka Y., Watanabe H. , Tatarazako N.
Name of Society : SETAC Europe 23rd Annual Meeting (2013)
Name of Proceedings : Abstracts, 390 (TH128)
Estimation of biological impact of surface water samples in Kasukawa River using algae, daphnids and fish

Presenter : Watanabe H., Yin W., Abe R., Takanobu H., Nakamura A., Yamamuro I., Tatarazako N.
Name of Society : SETAC EUROPE 23rd Annual Meeting (2013)
Name of Proceedings : Abstracts, 248
Mixture toxicity of pharmaceuticals detected in treated municipal wastewater to three aquatic organisms (algae, daphnids and fish)

Presenter : Watanabe H., Abe R., Takanobu H., Nakamura A., Suzuki T., Hirose A., Nishimura T., Tatarazako N.
Name of Society : SETAC EUROPE 23rd Annual Meeting (2013)
Name of Proceedings : Abstracts, 248
Verification of Fish Multi-Generation Test with the Estrone Using Japanese Medaka (Oryzias latipes)

Presenter : Tatarazako N., Nakamura A., Watanabe H., Tamura I., Takanobu H., Iguchi T.
Name of Society : SETAC North America 34th Annual Meeting (2013)
Name of Proceedings : Abstracts, 186
Mixture toxicity of multiple herbicides present in commercial herbicide products in Japan

Presenter : Watanabe H., OGINO S., Tamura I., Takanobu H., Abe R., Koshio M., Tatarazako N.
Name of Society : Society of Environmental Toxicology and Chemistry North America 34th Annual Meeting (2013)
Name of Proceedings : Abstracts, 333
Efficacy of medaka TG229 in the screening of endocrine-disrupting chemicals

Presenter : Tatarazako N., Takanobu H. , Watanabe H. , Sawai Atsushi, Ohnishi Y., Nakamura A., Iguchi T.
Name of Society : SETAC Asia Pacific 2012 (2012)
Name of Proceedings : Abstracts, 179
The effects of nonylphenol ethoxylates having different ethylene oxide(EO)chain on fish, daphnia, and alga

Presenter : Tatarazako N., Oka T. , Watanabe H. , Takanobu H. , Abe R., Abe R., OGINO S., Shiraishi H.
Name of Society : 22th SETAC Eueope Annual Meeting/6th SETAC Europe Special Science Symposium (2012)
Name of Proceedings : Abstracts of 22th SETAC Eueope Annual Meeting/6th SETAC Europe Special Science Symposium, 131
Evaluation of toxicities of herbicides using short-term chronic tests of alga, daphnid and fish

Presenter : Oka T. , Watanabe H. , Abe R., Koshio M., Takanobu H. , OGINO S., Iguchi T., Tatarazako N.
Name of Society : 22th SETAC Eueope Annual Meeting/6th SETAC Europe Special Science Symposium (2012)
Name of Proceedings : Abstracts of 22th SETAC Eueope Annual Meeting/6th SETAC Europe Special Science Symposium
, 228
Assessment of urban road dust in Tokyo using whole sediment toxicity identification evaluation procedures

Presenter : Watanabe H. , Nakajima F., Tatarazako N., Kasuga I., Furumai H.
Name of Society : SETAC North America 32nd Annual Meeting (2011)
Name of Proceedings : Abstracts of SETAC North America 32nd Annual Meeting, 351

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WATANABE Haruna

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