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SUZUKI Takehiro

Researcher Name
SUZUKI Takehiro
Div (Section) name/title
Health and Environmental Risk Division（Molecular Pathology Section）／Senior Researcher
Research Subject
Studies on the epigenetic mechanisms by environmental chemicals
Degree(s)
Doctor of Engineering
Professional Qualification(s)
Biology,Biochemistry
Environmental Speciality Field
hazardous chemical substance
Membership of Academic Society
The Molecular Biology Society of Japan,The Japanese Society for Hygiene,The Japanese Society of Toxicology
Research Subject
  • Fiscal Year: 2020
    • 25099 : Research Program on Health and Environmental Safety
    • 25141 : Research Project on Health Impacts of Chemicals on Children and Future Generations
    • 25196 : Project for the Promotion of Environmental Genomics Studies
    • 25250 : Studies on the Effects of Environmental Factors on the Onset/progression of Diseases
    • 25277 : Inheritance of environmental impacts on DNA methylation through sperm to the next generation embryos
    • 25352 : Fundamental Study on the Basis of Health and Environmental Risk Research
    • 25409 : Analysis of mechanism of late-onset increase in hepatic tumor by gestational exposure to arsenic focusing on epithelial mesenchymal transition
  • Fiscal Year: 2019
    • 24696 : Research Program on Health and Environmental Safety
    • 24721 : Research Project on Health Impacts of Chemicals on Children and Future Generations
    • 24837 : Identification of sperm small RNAs involved in multigenerational health effects of environmental chemicals
    • 24838 : Inheritance of environmental impacts on DNA methylation through sperm to the next generation embryos
    • 24858 : Project for the Promotion of Environmental Genomics Studies
    • 24891 : Studies on the Effects of Environmental Factors on the Onset/progression of Diseases
    • 24977 : Fundamental Study on the Basis of Health and Environmental Risk Research
    • 24988 : Analysis of mechanism of late-onset increase in hepatic tumor by gestational exposure to arsenic focusing on epithelial mesenchymal transition
  • Fiscal Year: 2018
    • 24304 : Research project on health impacts of chemicals on children and future generations
    • 24355 : Research program on health and environmental safety
    • 24433 : Creation of network toward the establishment of environmental research foundation in Myanmar
    • 24446 : Project for The Promotion of Environmental Genomics studies
    • 24455 : Identification of sperm small RNAs involved in multigenerational health effects of environmental chemicals
    • 24504 : Studies on the effects of environmental factors on the onset/progression of diseases
    • 24512 : Analysis of mechanism of late-onset increase in hepatic tumor by gestational exposure to arsenic focusing on epithelial mesenchymal transition
    • 24553 : Fundamental study on the basis of health and environmental risk research
  • Fiscal Year: 2017
    • 23824 : Research project on health impacts of chemicals on children and future generations
    • 23847 : Research program on health and environmental safety
    • 23948 : Studies on the effects of environmental factors on the onset/progression of diseases
    • 23967 : Identification of sperm small RNAs involved in multigenerational health effects of environmental chemicals
    • 23969 : Development of new in vitro methods for detecting toxicity of chemicals
    • 23970 : Project for The Promotion of Environmental Genomics studies
    • 24010 : Creation of network toward the establishment of environmental research foundation in Myanmar
    • 24073 : Fundamental study on the basis of health and environmental risk research
  • Fiscal Year: 2016
    • 23414 : Research program on health and environmental safety
    • 23415 : Research project on health impacts of chemicals on children and future generations
    • 23484 : Project for The Promotion of Environmental Genomics studies
    • 23558 : Studies on the effects of environmental factors on the onset/progression of diseases
    • 23593 : Studies on epimutations that are involved in the transgenerational effects of environmental chemicals in mice
    • 23594 : Genome-wide DNA methylation analysis of sperm to explore the mechanism of hepatic tumor augmentation in the F2 by gestational arsenite exposure of F0 pregnant female
    • 23607 : Creation of network toward the establishment of environmental research foundation in Myanmar
    • 23711 : Fundamental study on the basis of health and environmental risk research
  • Fiscal Year: 2015
    • 23018 : Mechanism and evaluation system of the developmental health effects of environmental factors
    • 23256 : Studies on multigenerational late-onset effects of environmental chemicals
    • 23257 : Studies on epimutations that are involved in the transgenerational effects of environmental chemicals in mice
    • 23258 : Genome-wide DNA methylation analysis of sperm to explore the mechanism of hepatic tumor augmentation in the F2 by gestational arsenite exposure of F0 pregnant female
    • 23271 : Studies on the regulation of Fos family gene expression involved in late-onset increases of tumor induced by arsenic
    • 23277 : Establishment of an international cooperation for promoting arsenic research
  • Fiscal Year: 2014
    • 22606 : Mechanism and evaluation system of the developmental health effects of environmental factors
    • 22719 : Studies on multigenerational late-onset effects of environmental chemicals
    • 22721 : Studies on epimutations that are involved in the transgenerational effects of environmental chemicals in mice
    • 22722 : Establishment of an international cooperation for promoting arsenic research
    • 22881 : Studies on the regulation of Fos family gene expression involved in late-onset increases of tumor induced by arsenic
  • Fiscal Year: 2013
    • 22190 : Mechanism and evaluation system of the developmental health effects of environmental factors
    • 22475 : Exploration of molecular epidemiological indexes to health effects of environmental factors focusing on genetic and epigenetic mutation
    • 22476 : Studies on the regulation of Fos family gene expression involved in late-onset increases of tumor induced by arsenic
    • 22507 : Studies on multigenerational late-onset effects of environmental chemicals
    • 22544 : Establishment of an international cooperation for promoting arsenic research
  • Fiscal Year: 2012
    • 21761 : Mechanism and evaluation system of the developmental health effects of environmental factors
    • 21986 : Studies of factors contributing to the regulation of epigenetics
    • 22064 : Studies on the epigenetic mechanism of arsenic carcinogenesis on human liver cancer cell line
  • Fiscal Year: 2011
    • 21319 : Mechanism and evaluation system of the developmental health effects of environmental factors
    • 21480 : Studies of factors contributing to the regulation of epigenetics
    • 21481 : Studies on the mechanism of transcription factor dependent effects of environmental chemicals
    • 21550 : Studies on the epigenetic mechanism of arsenic carcinogenesis on human liver cancer cell line
  • Fiscal Year: 2010
    • 21051 : Studies to evaluate toxicityies of environmental chemicals focusing on their epigenetic effects
    • 21053 : Studies of factors contributing to the regulation of epigenetics
    • 21054 : Studies on the mechanism of tissue-specific modulation of AhR-dependent gene expression
    • 21055 : Studies on the mechanism of transcription factor dependent effects of environmental chemicals
  • Fiscal Year: 2009
    • 20483 : Studies to evaluate toxicityies of environmental chemicals focusing on their epigenetic effects
    • 20490 : Studies on the mechanism of transcription factor dependent effects of environmental chemicals
    • 20519 : Studies on the mechanism of tissue-specific modulation of AhR-dependent gene expression
    • 20521 : Development of the method for detecting the health effects using micro RNA
  • Fiscal Year: 2008
    • 20078 : Studies on the role of transcription factors that mediate organ- and cell-specific toxicity of environmental chemicals
    • 20139 : Studies to evaluate toxicityies of environmental chemicals focusing on their epigenetic effects
    • 20363 : Development of the method for detecting the health effects using micro RNA
  • Fiscal Year: 2007
    • 10516 : Studies on the role of transcription factors that mediate organ- and cell-specific toxicity of environmental chemicals
    • 10739 : Studies to evaluate toxicityies of environmental chemicals focusing on their epigenetic effects
  • Fiscal Year: 2006
    • 10050 : Studies on application of toxicogenomics for risk assessment of environmental pollutants
    • 10257 : Studies on the role of transcription factors that mediate organ- and cell-specific toxicity of environmental chemicals
  • Fiscal Year: 2005
    • 9521 : Studies on application of toxicogenomics for risk assessment of environmental pollutants
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Research Result (Publication)
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Research Result (Presentation)
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  • Research Presentation
  • Research Presentation
    PM2.5 Analysis Before and During COVID-19 in Yangon City, Myanmar
    Presenter : Tin-Tin-Win-Shwe, Aung W.Y., Thein Z.L., Suzuki T., Ishigaki Y., Fushimi A., Mar O., Nakajima D.
    Name of Society : 2020 Annual Meeting of the Society of Indoor Environment, Japan (2020)
    Name of Proceedings : -, 26
  • Research Presentation
    Maternal exposure to arsenic on social behavior in 41 and 74-week-old F2 male mice born to arsenic-exposed pregnant mice
    Presenter : Htway S.M., Suzuki T., Kyaw S., Nohara K., Tin-Tin-Win-Shwe
    Name of Society : 48th Myanmar Health Research Congress (2020)
    Name of Proceedings : Abstract, 112
  • Research Presentation
    Effect of maternal exposure to PM2.5 on OXTR DNA methylation of umbilical cord white blood cells
    Presenter : Nway N.C., Suzuki T., Nakajima D., Ishigaki Y., Tin-Tin-Win-Shwe, Mar O.
    Name of Society : 48th Myanmar Health Research Congress (2020)
    Name of Proceedings : Abstract, 180
  • Research Presentation
    DNA methylation changes in cord blood of pregnant woman in the area of high PM2.5 concentration in Myanmar
    Presenter : Suzuki T., Nway N.C., Tin-Tin-Win-Shwe, Nakajima D., Isigaki Y., Mar O., Nohara K.
    Name of Society : 5th International Forum in Sustainable Future in Asia (2020)
    Name of Proceedings : Abstracts, 80
  • Research Presentation
    Social Behavior and Related Gene Expression Changes in F2 Male Mice born to Gestationally Arsenite Exposed F1 Mice
    Presenter : HTWAY S.M., Suzuki T., KYAW S., Nohara K., Tin-Tin-Win-Shwe
    Name of Society : 5th International Forum in Sustainable Future in Asia, 5th NIES International Forum (2020)
    Name of Proceedings : Abstracts, 60
  • Research Presentation
    Effect of Maternal Exposure to PM2.5 on Proinflammatory Cytokine, Oxidative Stress Marker and Serotonin in Umbilical Cord Blood
    Presenter : NWAY N.C., Suzuki T., Nakajima D., ISHIGAKI Y., Tin-Tin-Win-Shwe, MAR O.
    Name of Society : 5th International Forum in Sustainable Future in Asia, 5th NIES International Forum (2020)
    Name of Proceedings : Abstracts, 73
  • Research Presentation
    Deterrnination of Personal Exposure to Particulate Matters by Pocket PM2.5 Sensor [Pro] in Middle_Aged Women in Myanmar
    Presenter : THEIN Z.L., AUNG W.Y., YI E.E.P.N., Maung C., NWAY N.C., Thant Z., Suzuki T., Ishigaki Y., MAR O., Nakajima D., Tin-Tin-Win-Shwe
    Name of Society : 5th International Forum in Sustainable Future in Asia, 5th NIES International Forum (2020)
    Name of Proceedings : Abstracts, 81
  • Research Presentation
    Seasonal and Regional Variation of Particulate Matter Pollutants (PM2.5 and PM10) Distribution in Yangon and Taunggyi Cites, Myanmar
    Presenter : Nway N.C., Aung W.Y., Yi E.E.P.N., Thant Z., Yagishita M., Ishigaki Y., Suzuki T., Nakajima D., Tin-Tin-Win-Shwe, Mar O.
    Name of Society : Myanmar Universities' Research Conference 2019 (2019)
    Name of Proceedings : Abstracts, 54
  • Research Presentation
    Determination of Particulate matter (PM2.5 and PM10) concentrations of seven Townships of Taunggyi City, Shan State
    Presenter : Nway N.C., Yi E.E.P.N., Aung W.Y., Yagishita M., Suzuki T., Ishigaki Y., Nakajima D., Tin-Tin-Win-Shwe, Mar O.
    Name of Society : 47th Myanmar Health Research Congress (2019)
    Name of Proceedings : Abstract, 144-145
  • Research Presentation
    Expression changes of cancer-related genes of the hepatocytes in the F1 and F2 generations of C3H mice maternally exposed to arsenite
    Presenter : Suzuki T., Nohara K.
    Name of Society : 47th Myanmar Health Research Congress (2019)
    Name of Proceedings : Abstracts, 140
  • Research Presentation
    The association between arsenic-related LINE-1 methylation changes and blood pressure in Bangladesh
    Presenter : Suzuki T., Nohara K., Hossain K., Hasibuzzaman M.M., Islam M.S., Rahman A., Paul S.K., Himeno S.
    Name of Society : 46th MYANMAR HEALTH RESEARCH CONGRESS (2018)
    Name of Proceedings : THE REPUBLIC OF THE UNION OF MYANMAR MINISTRY OF HEALTH AND SPORTS, 121-122
  • Research Presentation
    Monitoring of water quality in Inle Lake, Myanmar
    Presenter : Yagishita M., Thandar M., Suzuki T., Tin-Tin-Win-Shwe, Nakajima D., Maung N.S.
    Name of Society : 45th Myanmar Health Research Congress (2017)
    Name of Proceedings : Programme and Abstracts, 20
  • Research Presentation
    DNA microarray analysis of the hepatocyte of the F1 and F2 generation in C3H mice by gestational arsenite exposure
    Presenter : Suzuki T., Nohara K.
    Name of Society : 45th MYANMAR HEALTH RESEARCH CONGRESS (2017)
    Name of Proceedings : Abstracts, 92
  • Research Presentation
    Novel DNA methylation changes induced by gestational arsenite exposure in hepatic tumors in F2 mice
    Presenter : Okamura K., Nakabayashi K., Horibe Y., Kawai T., Suzuki T., Hata K., Nohara K.
    Name of Society : The 5th Annual Meeting of the Japan Society for Developmental Origins of Health and Disease (2016)
    Name of Proceedings : Abstracts, 5(1):41
  • Research Presentation
    DNA Methylation Change of LINE-1 Associated with Chronic Arsenic Exposure through a Cross Sectional Study in Bangladesh
    Presenter : Suzuki T., K.Hossain, Himeno, Nohara K.
    Name of Society : SOT 55th Annual Meeting and ToxExpo (2016)
    Name of Proceedings : Abstracts
  • Research Presentation
    The relationship between chronic arsenic exposure and DNA methylation levels of LINE-1 through a cross sectional study in Bangladesh
    Presenter : Suzuki T., Hossain S., Himeno S., Nohara K.
    Name of Society : 44th Myanmar Health Research Congress (2016)
    Name of Proceedings : Abstracts, 75-76
  • Research Presentation
    The Effects of Gestational Arsenite Exposure on the F2 Generation: Role of Epigenetics
    Presenter : Nohara K., Okamura K., Suzuki T., Hatada I, Hata K
    Name of Society : Society of Toxicology 54th Annual Meeting (2015)
    Name of Proceedings : Abstracts, 523
  • Research Presentation
    Gestational Arsenic Exposure Affects Gene Expression in the Kidney and Lung in the F1 and F2 Mice
    Presenter : Takumi S, Okamura K., Suzuki T., Hano H, Nohara K., Yanagisawa H
    Name of Society : Society of Toxicology 54th Annual Meeting (2015)
    Name of Proceedings : Abstracts, 422
  • Research Presentation
    Maternal Arsenic Exposure of C3H Mice Increases Hepatic Tumor with an Activating Mutation in the Oncogene Ha-ras in the F2 Generation
    Presenter : Nohara K., Okamura K., Suzuki T., Murai H., Ito T., Shinjo K., Kondo Y.
    Name of Society : SOCIETY OF TOXICOLOGY 53rd Annual Meeting (2014)
    Name of Proceedings : Abstracts
  • Research Presentation
    In Vivo Mutagenicity Assay of Arsenite Using Gpt Delta Transgenic Mice
    Presenter : Takumi S., Aoki Y., Sano T., Suzuki T., Nohmi T., Nohara K.
    Name of Society : SOCIETY OF TOXICOLOGY 53rd Annual Meeting (2014)
    Name of Proceedings : Abstracts
  • Research Presentation
    Identification of DNA Methylation Changes in the Liver Tumors Induced by Gestational Arsenic Exposure Using Genome-Wide Analysis
    Presenter : Suzuki T., Yamashita S., Ushijima T., Takumi S., Sano T., Michikawa T., Nohara K.
    Name of Society : SOCIETY OF TOXICOLOGY 53rd Annual Meeting (2014)
    Name of Proceedings : Abstracts
  • Research Presentation
    The Effects of Gestational Inorganic Arsenic Exposure in the Offspring and Future Generations
    Presenter : Nohara K., Suzuki T., Takumi S., Okamura K., Maekawa F.
    Name of Society : NIES Arsenic Workshop 2013 (2013)
    Name of Proceedings : Abstracts, 15
  • Research Presentation
    Genome-Wide and Site-Specific Analyses of DNA Methylation Changes Induced by Arsenic Exposure
    Presenter : Suzuki T., Nohara K.
    Name of Society : NIES Arsenic Workshop 2013 (2013)
    Name of Proceedings : Abstracts, 16
  • Research Presentation
    Late increases in tumorigenic stress and tumors with a Ha-ras mutation in the liver of adult male C3H mice gestationally exposed to arsenic
    Presenter : Nohara K., Suzuki T., Tateishi Y., Okamura K., Murai H., Takumi S., Maekawa F., Nishimura N., Ito T.
    Name of Society : Prenatal Programming and Toxicity（PPTOX）? Meeting (2012)
    Name of Proceedings : Abstracts
  • Research Presentation
    Late-onset gene expression changes in the livers of male C3H mice maternally exposed to arsenic: Implications for an increase in hepatic tumor incidence
    Presenter : Nohara K., Tateishi Y., Suzuki T., Murai H., Takumi S., Okamura K., Maekawa f. , Nishimura N., Ito T.
    Name of Society : SOCIETY OF TOXICOLOGY 51st Annual Meeting (2012)
    Name of Proceedings : Abstracts of SOCIETY OF TOXICOLOGY 51st Annual Meeting
  • Research Presentation
    Sex-dependent changes in genomic DNA methylation by methyl deficient diet and inorganic arsenic in the liver of mice
    Presenter : Nohara K., Sano T., Murai H., Kobayashi Y., Suzuki T., Tateishi Y., Matsumoto M., Nishimura N., Baba T.
    Name of Society : 第9回分子予防環境医学研究会 (2010)
    Name of Proceedings : 同予稿集, 38
  • Research Presentation
    The investigation of tissue-specific modulation of AhR-dependent gene expression
    Presenter : Suzuki T., Takamoto S., Nohara K.
    Name of Society : SOT 2009 (2009)
    Name of Proceedings : Abstracts
  • Research Presentation
    Alteration of global DNA methylation induced by a methyl deficient diet and inorganic arsenic intake in mice
    Presenter : Nohara K., Sano T., Murai H., Kobayashi Y., Suzuki T., Tateishi Y., Matsumoto M., Nishimura N., Baba T.
    Name of Society : 32nd Annu.Meet.Mol.Biol.Soc.Jpn. (2009)
    Name of Proceedings : Abstracts, 149
  • Research Presentation
    Sex-dependent effects of diet and arsenic on genomic DNA methylation
    Presenter : Nohara K., Murai H., Sano T., Kobayashi Y., Tateishi Y., Suzuki T., Matsumoto M., Nishimura N., Baba T.
    Name of Society : HORIBA/CDBIM Symp. -21st Century Adv.Mol.Toxicol.Environ.Chem.Pathog.Dis.- (2009)
    Name of Proceedings : Abstracts, 168
  • Research Presentation
    Histone deacetylases are involved in species-specific modulation of arylhydrocarbon receptor-dependent gene expression in humans and mice
    Presenter : Suzuki T., Nohara K.
    Name of Society : 27th Int.Symp.Halogenat.Persistent Org.Pollut.-DIOXIN 2007(Poster Session) (2007)
    Name of Proceedings : Organohalogen Compd., 69
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