Latest Update：2021/02/21 15:41:22

YANAGISAWA Rie

Researcher Name: YANAGISAWA Rie

Div (Section) name/title: Center for Health and Environmental Risk Research（Molecular Pathology Section）／Senior Researcher

Research Subject: Study on effects of exposure to environmental chemicals in allergic and metabolic diseases

Degree(s): PhD

Professional Qualification(s): Medicine,Biochemistry

Environmental Speciality Field: toxicology,immunology

Membership of Academic Society: Japanese Society of Allergology,The Japanese Society for Hygiene,Japanese Society for Atmospheric Environment,Japanese Society of Immunotoxicology

Research Subject

Fiscal Year: 2020
- 25099 : Research Program on Health and Environmental Safety
- 25141 : Research Project on Health Impacts of Chemicals on Children and Future Generations
- 25243 : Comprehensive and systematic study for control/eradication of allergic diseases via environmental and medical approaches
- 25250 : Studies on the Effects of Environmental Factors on the Onset/progression of Diseases
- 25300 : Analysis of pathogenic mechanism of allergic inflammation via the activation of eye immunity due to exposure to environmental chemicals
- 25353 : Study on Global Mercury Dynamics and Risk Management of Mercury
- 25354 : Integration of sub-themes in S17 through development of risk management system, and development of risk assessment methodology under non-steady state environment by disaster and accidents
Fiscal Year: 2019
- 24696 : Research Program on Health and Environmental Safety
- 24721 : Research Project on Health Impacts of Chemicals on Children and Future Generations
- 24819 : Study on the relationship between changes in gut microbiota induced by chemicals in house dust and the disturbance of higher-order biological function.
- 24824 : Comprehensive and systematic study for control/eradication of allergic diseases via environmental and medical approaches
- 24891 : Studies on the Effects of Environmental Factors on the Onset/progression of Diseases
- 24978 : Study on Global Mercury Dynamics and Risk Management of Mercury
- 24979 : Integration of sub-themes in S17 through development of risk management system, and development of risk assessment methodology under non-steady state environment by disaster and accidents
Fiscal Year: 2018
- 24304 : Research project on health impacts of chemicals on children and future generations
- 24355 : Research program on health and environmental safety
- 24445 : Comprehensive and systematic study for control/eradication of allergic diseases via environmental and medical approaches
- 24504 : Studies on the effects of environmental factors on the onset/progression of diseases
- 24516 : Study on the relationship between changes in gut microbiota induced by chemicals in house dust and the disturbance of higher-order biological function.
- 24556 : Study on global mercury dynamics and risk management of mercury
Fiscal Year: 2017
- 23824 : Research project on health impacts of chemicals on children and future generations
- 23847 : Research program on health and environmental safety
- 23896 : Study on the effects of exposure to flame retardants to the onset and/or progression of allergic asthma in obese subjects.
- 23899 : The relationship between the gut microbiota and modern diseases
- 23900 : Impact of brominated flame retardants in obesity and obesity-related metabolic disorders
- 23902 : Study on the relationship between changes in gut microbiota induced by chemicals in house dust and the disturbance of higher-order biological function.
- 23948 : Studies on the effects of environmental factors on the onset/progression of diseases
- 23949 : Comprehensive and systematic study for control/eradication of allergic diseases via environmental and medical approaches
- 24198 : Study on the health impacts of environmental heat exposure and differences in the susceptibility
Fiscal Year: 2016
- 23414 : Research program on health and environmental safety
- 23415 : Research project on health impacts of chemicals on children and future generations
- 23524 : The effects of environmental pollutants on the gut microbiota.
- 23525 : Impact of brominated flame retardants in obesity and obesity-related metabolic disorders.
- 23527 : The feasibility study of the effects of environmental pollutants on the gut microbiota and its relationship to modern disease.
- 23528 : Study on the effects of exposure to flame retardants to the onset and/or progression of allergic asthma in obese subjects.
- 23558 : Studies on the effects of environmental factors on the onset/progression of diseases
- 23743 : Comprehensive and systematic study for control/eradication of allergic diseases via environmental and medical approaches
- 23745 : Study on the health impacts of environmental heat exposure and differences in the susceptibility
Fiscal Year: 2015
- 23018 : Mechanism and evaluation system of the developmental health effects of environmental factors
- 23081 : Effects of methylmercury to immune response.
- 23082 : Impact of brominated flame retardants in obesity and obesity-related metabolic disorders.
- 23333 : Pulmonary carcinogenic risk assessment of past exposure of suspended particulate matter in ambient air
Fiscal Year: 2014
- 22606 : Mechanism and evaluation system of the developmental health effects of environmental factors
- 22706 : Impact of brominated flame retardants in obesity and obesity-related metabolic disorders.
- 22931 : Pulmonary carcinogenic risk assessment of past exposure of suspended particulate matter in ambient air
- 22941 : Effects of methylmercury to immune response.
- 22948 : Health effects of secondary organic aerosols derived from diesel exhaust.
Fiscal Year: 2013
- 22190 : Mechanism and evaluation system of the developmental health effects of environmental factors
- 22278 : Studies on the mechanisms via which environmental pollutants enhance allergy, with special emphasis on the intercellular and intracellular networks
- 22279 : Studies on the effects of environmental chemicals on nervous and immunological systems during developmental period
- 22314 : Impact of brominated flame retardants in obesity and obesity-related metabolic disorders.
- 22570 : Health effects of secondary organic aerosols derived from diesel exhaust.
Fiscal Year: 2012
- 21761 : Mechanism and evaluation system of the developmental health effects of environmental factors
- 21805 : Studies on the mechanisms via which environmental pollutants enhance allergy, with special emphasis on the intercellular and intracellular networks
- 21806 : Evaluation of biological effects of aerosol
- 21808 : Studies on the effects of environmental chemicals on nervous and immunological systems during developmental period
- 21883 : Effects of environmental chemicals in obesity and obesity-related diseases.
Fiscal Year: 2010
- 20856 : Effects of environmental chemicals in allergic diseases.
- 20859 : Effects of environmental chemicals in obesity and obesity-related diseases.
- 20977 : Health risk assessment methods of environmental chemicals that cause sensitivity
- 21019 : Evaluation of biological effects of aerosol
- 21020 : International comparison study on waste management and recycle institutions, and integrated system analysis of chemical substance management
- 21029 : Studies on the mechanisms via which environmental pollutants enhance allergy, with special emphasis on the intercellular and intracellular networks
- 21031 : Studies on the effects of environmental chemicals on nervous and immunological systems during developmental period
- 21051 : Studies to evaluate toxicityies of environmental chemicals focusing on their epigenetic effects
- 21127 : Study of environmental origins of psychiatric disorders
Fiscal Year: 2009
- 20397 : Studies on the enhancing effets of environmental chemicals on fatty liver
- 20400 : evaluation of biological aeffects of aerosol
- 20447 : Study on lung function and cytokine production in pulmonary emphysema models of rodents and evaluation of effects of environmental pollutants
- 20448 : Adverse impacts of environmental nanoparticles on sensitive respiratory disorders
- 20449 : Risk assessment of inhaled nanoparticle rich diesel exhaust focusing the impacts on brain, liver, kidney, and reproductive organs
- 20467 : Effects of exposure to pesticide residue on atopic dermatitis-like skin lesions in mice.
- 20468 : Role of peroxiredoxin I in respiratory diseases.
- 20469 : Effects of pulmpnary exposure to diesel exhaust particles in fatty liver.
- 20483 : Studies to evaluate toxicityies of environmental chemicals focusing on their epigenetic effects
- 20536 : Health risk assessment methods of environmental chemicals that cause sensitivity
- 20541 : Study of environmental origins of psychiatric disorders
- 20799 : International comparison study on waste management and recycle institutions, and integrated system analysis of chemical substance management
Fiscal Year: 2008
- 20062 : Effects of exposure to pesticide residue on atopic dermatitis-like skin lesions in mice.
- 20063 : Role of peroxiredoxin I in respiratory diseases.
- 20139 : Studies to evaluate toxicityies of environmental chemicals focusing on their epigenetic effects
- 20146 : Studies on the health effects of nanomaterials with special emphasis on the sensitive populations
- 20147 : Development of evaluation system which can predict the effects of environmental chemicals on hypersensitive subjects with atopy using dendritic cells
- 20152 : Studies on the enhancing effets of environmental chemicals on fatty liver
- 20153 : respiratory and immunological effects of <br>nanoparticles and nanomaterials
- 20177 : Study of environmental origins of psychiatric disorders
- 20281 : Health risk assessment methods of environmental chemicals that cause sensitivity
- 20355 : Study on lung function and cytokine production in pulmonary emphysema models of rodents and evaluation of effects of environmental pollutants
Fiscal Year: 2007
- 10383 : Development of methods for health effect assessment of hazardous chemicals using DNA chip
- 10421 : Development and evaluation of the in vivo model which elucidate the effects of environmental chemicasls on allergic disordes
- 10500 : Effects of nano materials in atopic dermatitis-like symptoms.
- 10564 : Studies on the health effects of nanomaterials with special emphasis on the sensitive populations
- 10568 : Study of environmental origins of psychiatric disorders
- 10583 : Health risk assessment methods of environmental chemicals that cause sensitivity
- 10668 : Role of peroxiredoxin I in respiratory diseases.
- 10677 : Development of evaluation system which can predict the effects of environmental chemicals on hypersensitive subjects with atopy using dendritic cells
- 10739 : Studies to evaluate toxicityies of environmental chemicals focusing on their epigenetic effects
Fiscal Year: 2006
- 10145 : Development and evaluation of the in vivo model which elucidate the effects of environmental chemicasls on allergic disordes
- 10241 : Effects of nano materials in atopic dermatitis-like symptoms.
- 10301 : Study of environmental origins of psychiatric disorders
- 10316 : Health risk assessment methods of environmental chemicals that cause sensitivity
Fiscal Year: 2005
- 9380 : Effects of environmental hormones on respiratory and immune systems
- 9408 : Diesel exhaust as an environmental hormone
- 9616 : Effects of nano materials on atopic dermatitis in NcNga mice
- 9640 : Development and evaluation of the in vivo model which elucidate the effects of environmental chemicasls on allergic disordes
Fiscal Year: 2004
- 8985 : Study on environmental behavior and health effects of airborne fine particulate matter such as PM2.5 and DEP
- 9014 : Effects of environmental hormones on respiratory and immune systems
- 9043 : Diesel exhaust as an environmental hormone
- 9056 : Risk assessment of environmental chemicals on allergic reactions and diseases
- 9147 : Effects of diesel exhaust partiles on diabetes mellitus and its complications
- 9149 : Risk assesment for environmental beta-glucan and endotoxin
- 9150 : Amelioration of health effects by environmental factors
Fiscal Year: 2003
- 8732 : Effects of environmental hormones on respiratory and immune systems
- 8761 : Diesel exhaust as an environmental hormone
- 8779 : Risk assessment of environmental chemicals on allergic reactions and diseases
- 8862 : Evaluation of toxicity and measurement of environmental endotoxin
- 8863 : Amelioration of adversehealth effects of environmental factors by functioning foods
Fiscal Year: 2002
- 8416 : Effects of diesel exhaust on cardiorespiratory disorders
- 8512 : Effects of environmental hormones on respiratory and immune systems
- 8544 : Diesel exhaust as an environmental hormone
- 8565 : Evaluation of toxicity and measurement of environmental endotoxin
- 8566 : Amelioration of adverse health effects of environmental factors
- 8575 : Risk assessment of environmental chemicals on allergic reactions and diseases
Fiscal Year: 2001
- 8203 : Effects of diesel exhaust on cardiorespiratory disorders
- 8277 : Effects of environmental hormones on respiratory and immune system
- 8304 : Diesel exhaust as an environmental hormone

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Research Result (Publication)

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Original Paper
Review

Original Paper
Dietary exposure to bisphenol A affects memory function and neuroimmune biomarkers in allergic asthmatic mice

Presenter : Tin-Tin-Win-Shwe, Yanagisawa R., Koike E., Takano H.
Title : , Journal of Applied Toxicology, 1-10 (2021)
Original Paper
The impact of oral exposure to low-dose tris(2-butoxyethyl)phosphate in allergic asthmatic mice

Presenter : Yanagisawa R., Koike E., Tin-Tin-Win-Shwe, Kawaguchi M., Takano H.
Title : , Journal of Applied Toxicology, 40(11):1498-1510 (2020)
Original Paper
Novel toxicity of tris(1,3-dichloro-2-propyl) phosphate in adult male rats

Presenter : Shohei Kobayashi, Kodai Abe, Anna Isobe, Airi Nakayama, Takahiro Akimoto, Taichi Hatakeyama, Yoshiaki Saito, Yanagisawa R., Koike E., Suzuki N., Maiko Kawaguchi, Ryo Ohta
Title : , Journal of Applied Toxicology, 1-6 (2020)
Original Paper
Toxicokinetics of methylmercury in diabetic KK-Ay mice and C57BL/6 mice

Presenter : Yamamoto M., Yanagisawa R., Sakai A., Mogi M., Shuto S., Shudo M., Kashiwagi H., Kudo M., Nakamura M., Sakamoto M.
Title : , Journal of Applied Toxicology, 1-13 (2020)
Original Paper
Decabromodiphenyl ether exacerbates hyperglycemia in diet-induced obese mice

Presenter : Yanagisawa R., Koike E., Tin-Tin-Win-Shwe, Hirohisa Takano
Title : , Toxicology, 15(412):12-18 (2019)
Original Paper
Hatano rats are a suitable metabolic syndrome model for studying feeding behavior, blood pressure levels, and percent body fat

Presenter : Isobe A., Shimada T., Aburada M., Yanagisawa R., Sakawa T., Nakamura T., Himi T., Ohta R., Kawaguchi M.
Title : , The Journal of Veterinary Medical Science, 81(1):147-154 (2019)
Original Paper
Memory function, neurological and immunological biomarkers in allergic asthmatic mice intratracheally exposed to bisphenol A

Presenter : Tin-Tin-Win-Shwe, Yanagisawa R., Koike E., Takano H
Title : , International Journal of Environmental Research and Public Health, 16(3770):1-16 (2019)
Original Paper
Oral exposure to low dose bisphenol A aggravates allergic airway inflammation in mice

Presenter : Yanagisawa R., Koike E., Tin-Tin-Win-Shwe, Hirohisa Takano
Title : , Toxicology Reports, 6:1253-1262 (2019)
Original Paper
Effects of lactational exposure to low-dose BaP on allergic and non-allergic immune responses in mice offspring

Presenter : Yanagisawa R., Koike E., Tin-Tin-Win-Shwe, Ichinose T., Takano H.
Title : , Journal of Immunotoxicology , 15(1):31-40 (2018)
Original Paper
Exposure to low-dose bisphenol A during the juvenile period of development disrupts the immune system and aggravates allergic airway inflammation in mice

Presenter : Koike E., Yanagisawa R., Tin-Tin-Win-Shwe, Takano H.
Title : , International Journal of Immunopathology and Pharmacology, 32:1-14 (2018)
Original Paper
Change over time of the mutagenicity in the lungs of gpt delta transgenic mice by extract of airborne particles collected from ambient air in the Tokyo metropolitan area

Presenter : Aoki Y., Nakajima D., Matsumoto M., Yagishita M., Matsumoto M., Yanagisawa R., Goto S., Masumura K., Nohmi T.
Title : , Genes and Environment, 40(25): (2018)
Original Paper
Evaluation of neurobehavioral impairment in methylmercury-treated KK-Ay mice by dynamic weight-bearing test

Presenter : Megumi Yamamoto, Eriko Motomura, Yanagisawa R., Van Anh Thi Hoang, Masaki Mogi, Tomohisa Mori, Masaaki Nakamura, Motohiro Takeya, Komyo Eto
Title : , Journal of Applied Toxicology, 39:221-230 (2018)
Original Paper
Activation of interleukin-6 and -8 expressions by methylmercury in human U937 macrophages involves RelA and p50

Presenter : Yamamoto M., Khan N., Muniroh M., Motomura E., Yanagisawa R., Matsuyama T., Vogel C.F.A.
Title : , Journal of Applied Toxicology, 37(5):611-620 (2017)
Original Paper
Brominated flame retardants, hexabromocyclododecane and tetrabromobisphenol A, affect proinflammatory protein expression in human bronchial epithelial cells via disruption of intracellular signaling

Presenter : Koike E., Yanagisawa R., Takano H.
Title : , Toxicology in Vitro, 32:212-219 (2016)
Original Paper
Low-dose benzo[a]pyrene aggravates allergic airway inflammation in mice

Presenter : Yanagisawa R., Koike E., Tin-Tin-Win-Shwe, Ichinose T., Takano H.
Title : , Journal of Applied Toxicology, 36:1496-1504 (2016)
Original Paper
Nano-Sized Secondary Organic Aerosol of Diesel Engine Exhaust Origin Impairs Olfactory-Based Spatial Learning Performance in Preweaning Mice

Presenter : Tin-Tin-Win-Shwe, Chaw Kyi Tha thu, Yadanar Moe, Maekawa F., Yanagisawa R., Furuyama A., Tsukahara, Fujitani Y., Hirano S.
Title : , Nanomaterials, 2015(5):1147-1162 (2015)
Original Paper
Penta- and octa-bromodiphenyl ethers promote proinflammatory protein expression in human bronchial epithelial cells in vitro

Presenter : Koike E., Yanagisawa R., Takigami H., Takano H.
Title : , Toxicology in Vitro, 28:327-333 (2014)
Original Paper
Impaired Lipid and Glucose Homeostasis in Hexabromocyclododecane-Exposed Mice Fed a High-Fat Diet

Presenter : Yanagisawa R., Koike E., Tin-Tin-Win-Shwe, Megumi Y., Takano H.
Title : , Environmental Health Perspectives, 122(3):277-283 (2014)
Original Paper
Toxicological effects of polycyclic aromatic hydrocarbons and their derivatives on respiratory cells

Presenter : Koike E., Yanagisawa R., Takano H.
Title : , Atmospheric Environment, 97:529-536 (2014)
Original Paper
Increased methylmercury toxicity related to obesity in diabetic KK-Ay mice

Presenter : Yamamoto M., Yanagisawa R., Motomura E., Nakamura M., Sakamoto M., Takeya M, Eto K.
Title : , Journal of Applied Toxicology, 34(8):914-923 (2014)
Original Paper
Effects of oral administration of di-(2-ethylhexyl) and diisononyl phthalates on atopic dermatitis in NC/Nga mice.

Presenter : Sadakane K., Ichinose T., Takano H., Yanagisawa R., Koike E.
Title : , Immunopharmacology and Immunotoxicology, 36(1):61-69 (2014)
Original Paper
Organic Chemicals in Diesel Exhaust Particles Enhance Picryl Chloride-Induced Atopic Dermatitis in NC/Nga Mice.

Presenter : Sadakane K., Ichinose T., Takano H., Yanagisawa R., Inoue KI., Kawazato H., Yasuda A., Hayakawa K.
Title : , International Archives of Allergy and Immunol.ogy, 162:7-15 (2013)
Original Paper
Expression levels of neuroimmune biomarkers in hypothalamus of allergic mice after phthalate exposure

Presenter : Tin-Tin-Win-Shwe, Yanagisawa R., Koike E., Nitta H., Takano H.
Title : , Journal of Applied Toxicology , 33(10):1071-1078 (2013)
Original Paper
Role of metallothionein in murine experimental colitis.

Presenter : Tsuji T., Naito Y., Takagi T., Kugai M., Yoriki H., Horie R., Fukui A., Mizushima K., Hirai Y., Katada K., Kamada K., Uchiyama K., Handa O., Konishi H., Yagi N., Ichikawa H., Yanagisawa R., Suzuki J., Takano H., Satoh M., Yoshikawa T.
Title : , International Journal of Molecular Medicine , 31(5):1037-1046 (2013)
Original Paper
Brominated flame retardants stimulate mouse immune cells in vitro

Presenter : Koike E., Yanagisawa R., Takigami H., Takano H.
Title : , Journal of applied toxicology , 33(12):1451-1459 (2013)
Original Paper
The alkylphenols 4-nonylphenol, 4-tert-octylphenol and 4-tert-butylphenol aggravate atopic dermatitis-like skin lesions in NC/Nga mice

Presenter : Sadakane K., Ichinose T., Takano H., Yanagisawa R., Koike E., Inoue K.
Title : , Journal of Applied Toxicology, 34(8):893-902 (2013)
Original Paper
Asian sand dust enhances murine lung inflammation caused by Klebsiella pneumoniae

Presenter : He M., Ichinose T., Yoshida S., Yamamoto S., Inoue Ken-ichiro, Takano H., Yanagisawa R., Nishikawa M., Mori I., Sun G., Shibamoto T.
Title : , Toxicology and Applied Pharmacology, 258(2):237-247 (2012)
Original Paper
Peroxiredoxin I null mice exhibits reduced acute lung inflammation following ozone exposure.

Presenter : Yanagisawa R., Warabi E., Inoue K., Yanagawa T., Koike E., Ichinose T., Takano H., Ishii T
Title : , The Journal of Biochemistry, 152(6):595-601 (2012)
Original Paper
Effects of diisononyl phthalate on atopic dermatitis in vivo and immunologic responses in vitro

Presenter : Koike E., Yanagisawa R., Sadakane K., Inoue Ken-ichiro, Ichinose T., Takano H.
Title : , Environ.Health Perspect., 118(4):472-478 (2010)
Original Paper
Size effects of polystyrene nanoparticles on atopic Dermatitis-Like skin lesions in NC/Nga mice

Presenter : Yanagisawa R., Takano H., Inoue Ken-ichiro, Koike E., Sadakane K., Ichinose T.
Title : , Int.J.Immunopathol.Pharmacol., 23(1):131-141 (2010)
Original Paper
Urban particulate matter in Beijing, China, enhances allergen-induced murine lung eosinophilia

Presenter : He M., Ichinose T., Yoshino S, Nishikawa M., Mori I., Yanagisawa R., Takano H., Inoue Ken-ichiro, Sun G., Shibamoto T.
Title : , Inhal.Toxicol., 22(9):709-718 (2010)
Original Paper
Extensive analysis of elastase-induced pulmonary emphysema in rats: ALP in the lung, a new biomarker for disease progression?

Presenter : Inoue Ken-ichiro, Koike E., Yanagisawa R., Takano H.
Title : , J.Clin.Biochem.Nutr., 46(2):168-176 (2010)
Original Paper
Size effects of latex nanomaterials on lung inflammation in mice

Presenter : Inoue Ken-ichiro, Takano H., Yanagisawa R., Koike E., Shimada A
Title : , Toxicol.Appl.Pharmacol., 234(1):68-76 (2009)
Original Paper
Effects of pulmonary exposure to diesel exhaust particles on extrathoracic CD4 polarization in asthmatic mice

Presenter : Inoue Ken-ichiro, Koike E., Yanagisawa R., Takano H.
Title : , Immunopharmacol.Immunotoxicol., 31(1):71-74 (2009)
Original Paper
Effects of diesel exhaust particles on antigen-presenting cells and antigen-specific Th immunity in mice

Presenter : Inoue Ken-ichiro, Koike E., Takano H., Yanagisawa R., Ichinose T., Yoshikawa T
Title : , Exp.Biol.Med., 234:200-209 (2009)
Original Paper
Titanium dioxide nanoparticles aggravate atopic dermatitis-like skin lesions in NC/Nga mice

Presenter : Yanagisawa R., Takano H., Inoue Ken-ichiro, Koike E., Kamachi T., Sadakane K., Ichinose T.
Title : , Exp.Biol.Med., 234:314-322 (2009)
Original Paper
Di-(2-ethylhexyl) phthalate affects immune cells from atopic prone mice in vitro

Presenter : Koike E., Inoue Ken-ichiro, Yanagisawa R., Takano H.
Title : , Toxicology, 259(1/2):54-60 (2009)
Original Paper
Peroxiredoxin ? is a negative regulator of Th2-dominant allergic asthma

Presenter : Inoue Ken-ichiro, Takano H., Koike E., Warabi E., Yanagawa T., Yanagisawa R., Ishii T.
Title : , Int.Immunopharmacol., 9(11):1281-1288 (2009)
Original Paper
Pulmonary exposure to soluble cell wall beta-(1, 3)-glucan of aspergillus induces proinflammatory response in mice

Presenter : Inoue Ken-ichiro, Koike E., Yanagisawa R., Adachi Y., Ishibashi K., Ohno N., Takano H.
Title : , Int.J.Immunopathol.Pharmacol., 22(2):287-297 (2009)
Original Paper
Effects of multi-walled carbon nanotubes on a murine allergic airway inflammation model

Presenter : Inoue Ken-ichiro, Koike E., Yanagisawa R., Hirano S., Nishikawa M., Takano H.
Title : , Toxicol.Appl.Pharmacol., 237(3):306-316 (2009)
Review
Airborne particles in pulmonary diseases

Presenter : Inoue Ken-ichiro, Takano H., Yanagisawa R., Yoshikawa T
Title : , Curr.Respir.Med.Rev., 5:69-72 (2009)
Original Paper
Soluble cell wall β-glucan of candida induces/enhances apoposis and oxidative stress in murine lung

Presenter : Inoue Ken-ichiro, Takano H., Oda T., Yanagisawa R., Tamura H., Adachi Y., Ishibashi K., Ohno N.
Title : , Immunopharmacol.Immunotoxicol., 31(1):140-145 (2009)
Original Paper
Urinary trypsin inhibitor protects against liver injury and coagulation pathway dysregulation induced by lipopolysaccharide/D-galactosamine in mice

Presenter : Takano H., Inoue Ken-ichiro, Shimada A, Sato H., Yanagisawa R., Yoshikawa T
Title : , Lab.Invest., 89:833-839 (2009)
Original Paper
Pulmonary exposure to soluble cell wall β-(1, 3)-glucan of aspergillus induces proinflammatory response in mice

Presenter : Inoue Ken-ichiro, Koike E., Yanagisawa R., Adachi Y., Ishibashi K., Ohno N., Takano H.
Title : , Int.J.Immunopathol.Pharmacol., 22(2):287-297 (2009)
Original Paper
Candida soluble cell wall β-glucan facilitates ovalbumin-induced allergic airway inflammation in mice: Possible role of antigen-presenting cells

Presenter : Inoue Ken-ichiro, Takano H., Koike E., Yanagisawa R., Oda T., Tamura H., Adachi Y., Ishibashi K., Ohno N.
Title : , Respir.Res., 10(68):1-12 (2009)
Original Paper
Protective role of urinary trypsin in lung expression of proinflammatory cytokines accompanied by lethal liver injury in mice

Presenter : Inoue Ken-ichiro, Takano H., Sato H., Yanagisawa R., Yoshikawa T
Title : , Immunopharmacol.Immunotoxicol., 31(3):446-450 (2009)
Original Paper
Size effects of nanomaterials on lung inflammation and coagulatory disturbance

Presenter : Inoue Ken-ichiro, Takano H., Ohnuki M., Yanagisawa R., Sakurai M., Shimada A., Mizushima K., Toshikawa T.
Title : , Int.J.Immunopathol.Pharmacol., 21(1):197-206 (2008)
Original Paper
Pulmonary exposure to carbon black nanoparticles increases the number of antigen-presenting cells in murine lung

Presenter : Koike E., Takano H., Inoue Ken-ichiro, Yanagisawa R., Aoyagi H., Shinohara R., Kobayashi T.
Title : , Int.J.Immunopathol.Pharmacol., 21(1):35-42 (2008)
Original Paper
Effects of maternal exposure to Di-(2-ethylhexyl) phthalate during fetal and/or neonatal periods on atopic dermatitis in male offspring

Presenter : Yanagisawa R., Takano H., Inoue Ken-ichiro, Koike E., Sadakane.K, Ichinose.T
Title : , Environ.Health Perspect., 116(9):1136-1141 (2008)
Original Paper
Accelerated differentiation of bone marrow-derived dendritic cells in atopic prone mice

Presenter : Koike E., Takano H., Inoue Ken-ichiro, Yanagisawa R.
Title : , Int.Immunopharmacol., 8(-1314):1737-1743 (2008)
Original Paper
Role of metallothionein in lung inflammation induced by ozone exposure in mice

Presenter : Inoue Ken-ichiro, Takano H., Theerayuth Kaewamatawong, Shimada A, Suzuki J., Yanagisawa R., Tasaka S, Ishizaka A, Satoh M
Title : , Free Radical Biol.Med., 45(12):1714-1722 (2008)
Original Paper
Effects of pulmonary exposure to carbon nanotubes on lung and systemic inflammation with coagulatory disturbance induced by lipopolysaccharide in mice

Presenter : Inoue Ken-ichiro, Takano H., Koike E., Yanagisawa R., Tasaka S, Ishizaka A, Shimada A
Title : , Soc.Exp.Biol.Med., 233:1583-1590 (2008)
Original Paper
Antioxidative role of interleukin-6 in septic lung injury in mice

Presenter : Inoue Ken-ichiro, Takano H., Yanagisawa R., Shimada A, Satoh M, Yoshino S, Yamaki K, Yoshikawa T
Title : , Int.J.Immunopathol.Pharmacol., 21(3):501-507 (2008)
Original Paper
Impact of diesel exhaust particles on Th2 response in the lung in asthmatic mice

Presenter : Inoue Ken-ichiro, Koike E., Yanagisawa R., Takano H.
Title : , J.Clin.Biochem.Nutr., 43:199-200 (2008)
Review
Protective effects of urinary trypsin inhibitor on systemic inflammatory response induced by lipopolysaccharide

Presenter : Inoue Ken-ichiro, Takano H., Yanagisawa R., Yoshikawa T
Title : , J.Clin.Biochem.Nutr., 43:139-142 (2008)
Original Paper
Carbon black nanoparticles promote the maturation and function of mouse bone marrow-derived dendritic cells

Presenter : Koike E., Takano H., Inoue Ken-ichiro, Yanagisawa R., Kobayashi T.
Title : , Chemosphere, 73(3):371-376 (2008)
Original Paper
Developmental exposure to pentachlorophenol affects the expression of thyroid hormone receptor β1 and synapsin ? in brain, resulting in thyroid function vulnerability in rats

Presenter : Kawaguchi M, Morohoshi K., Saita E., Yanagisawa R., Watanabe G., Takano H., Morita M., Imai H., Taya K., Himi T.
Title : , Endocrine, 33(3):277-284 (2008)
Original Paper
Cacao liquor proanthocyanidins inhibit lung injury induced by diesel exhaust particles

Presenter : Yasuda A., Takano H., Osakabe N., Sanbongi C., Fukuda K., Natsume M., Yanagisawa R., Inoue Ken-ichiro, Kato Y., Osawa T., Yoshikawa T
Title : , Int.J.Immunopathol.Pharmacol., 21(2):279-288 (2008)
Original Paper
Effects of Asian sand dust, Arizona sand dust, amorphous silica and aluminum oxide on allergic inflammation in the murine lung

Presenter : Ichinose T., Yoshida S., Sadakane K., Takano H., Yanagisawa R., Inoue Ken-ichiro, Nishikawa M., Mori I., Kawazato H., Yasuda A., Shibamoto T.
Title : , Inhal.Toxicol., 20(7):685-694 (2008)
Original Paper
Inhibition of the antigen-induced activation of RBL-2H3 cells by sinomenine

Presenter : Huang F., Yamaki K, Tong X., Fu L., Zhang R., Cai Y., Yanagisawa R., Inoue Ken-ichiro, Takano H., Yoshino S
Title : , Int.Immunopharmacol., 8(3):502-507 (2008)
Gene expression analysis of murine lungs following pulmonary exposure to Asian sand dust particles

Presenter : Yanagisawa R., Takano H., Ichinose T.(*1), Mizushima K.(*2), Nishikawa M., Mori I., Inoue Ken-ichiro., Sadakane K.(*1), Yoshikawa T.(*2)
Title : , Exp.Biol.Med., 232:1109-1118 (2007)
Effects of inhaled nanoparticles on acute lung injury induced by lipopolysaccharide in mice

Presenter : Inoue Ken-ichiro., Takano H., Yanagisawa R., Hirano S., Kobayashi T., Fujitani Y., Shimada A.(*1), Yoshikawa T.(*2)
Title : , Toxicology, 238:99-110 (2007)
Candida soluble cell wall-beta-D-glucan induces lung inflammation in mice

Presenter : Inoue Ken-ichiro, Takano H., Oda T.(*1), Yanagisawa R., Tamura H.(*1), Ohno N.(*2), Adachi Y.(*2), Ishibashi K.(*2), Yoshikawa T
Title : , Int.J.Immunopathol.Pharmacol., 20(3):499-508 (2007)
Effects of nanoparticles on lung physiology in the presence or absence of antigen

Presenter : Inoue Ken-ichiro, Takano H., Yanagisawa R., Sakurai M, Abe S, Yoshino S.(*1), Yamaki K.(*1), Yoshikawa T.(*2)
Title : , Int.J.Immunopathol.Pharmacol., 20(4):737-744 (2007)
Dietary supplementation with cacao liquor proanthocyanidins prevents elevation of blood glucose levels in diabetic obese mice

Presenter : Tomaru M.(*1), Takano H., Osakabe N.(*2), Yasuda A.(*2), Inoue Ken-ichiro., Yanagisawa R., Ohwatari T.(*1), Uematsu H.(*1)
Title : , Nutrition, 23:351-355 (2007)
Original Paper
Mutations in the lungs of gpt delta transgenic mice following inhalation of diesel exhaust

Presenter : Hashimoto A.H., Amanuma K., Hiyoshi K., Sugawara Y., Goto S., Yanagisawa R., Takano H., Masumura K., Nohmi T., Aoki Y.
Title : , Environ.Mol.Mutagen., 48(8):682-693 (2007)
Components of diesel exhaust particles diversely enhance a variety of respiratory diseases related to infection or allergy: Extracted organic chemicals and the residual particles after extraction differently affect respiratory diseases

Presenter : Takano H., Yanagisawa R., Inoue Ken-ihciro
Title : , J.Clin.Biochem.Nutr., 40:101-107 (2007)
Naphthoquinone enhances antigen-related airway inflammation in mice

Presenter : Inoue K., Takano H., Hiyoshi K.(*1), Ichinose T.(*2), Sadakane K.(*2), Yanagisawa R., Tomura S.(*1), Kumagai Y.(*3)
Title : , Eur.Respir.J., 29(2):259-267 (2007)
Effects of diesel exhaust particles on cytokine production by splenocytes stimulated with lipopolysaccharide

Presenter : Takano H., Inoue K., Yanagisawa R.
Title : , J.Appl.Toxicol., 27:95-100 (2007)
Components of diesel exhaust particles differentially affect Th1/Th2 response in a murine model of allergic airway inflammation

Presenter : Yanagisawa R., Takano H., Inoue K., Ichinose T.(*1), Sadakane K.,(*1), Yoshino S.(*2), Yamaki K.(*2), Yoshikawa T.(*3), Hayakawa K.(*4)
Title : , Clin.Exp.Allergy, 36:386-395 (2006)
Di-(2-ethylhexyl) phthalate enhances atopic dermatitis-like skin lesions in mice

Presenter : Takano H., Yanagisawa R., Inoue K., Ichinose T.(*1), Sadakane K.(*1), Yoshikawa T.(*2)
Title : , Environ.Health Perspect., 114(8):1266-1269 (2006)
Murine strain differences in 8-hydroxy-deoxyguanosine formation in hepatic DNA induced by oxidized lard and dietary oils

Presenter : Sadakane K.(*1), Ichinose T.(*1), Takano H., Abe M.(*1), Sera N.(*2), Yanagisawa R., Ochi H.(*3), Fujioka K.(*4), Lee K.-G.(*5), Shibamoto T.(*4)
Title : , Food Chem.Toxicol., 44:1372-1376 (2006)
Diesel exhaust particles synergistically enhance lung injury and oxidative stress induced by bacterial endotoxin

Presenter : Arimoto T., Inoue K., Yanagisawa R., Mason R.P.(*1), Takano H.
Title : , J.Clin.Biochem.Nutr., 38:133-137 (2006)
Suppression of Th1 and Th2 immune responses in mice by sinomenine,an alkaloid extracted from the Chinese medicinal plant Sinomenium acutum

Presenter : Feng H.(*1)(*2), Yamaki K.(*1), Takano H., Inoue K., Yanagisawa R., Yoshino S.(*1)
Title : , Planta Medica, 72:1383-1388 (2006)
Enhancement of mite allergen-induced eosinophil infiltration in the murine airway and local cytokine/chemokine expression by Asian sand dust.

Presenter : Ichinose T.(*1), Sadakane K.(*1), Takano H., Yanagisawa R., Nishikawa M., Mori I., Kawazato H.(*2), Yasuda A.(*3), Hiyoshi K.(*3), Shibamoto T.(*4)
Title : , J.Toxicol.Environ.Health A, 69:1571-1585 (2006)
Role of metallothionein in coagulatory disturbance and systemic inflammation induced by lipopolysaccharide mice

Presenter : Takano H., Inoue K., Shimada A.(*1), Wada E.(*1), Yanagisawa R.
Title : , FASEB J., 20(3):533-535 (2006)
Pulmonary exposure to diesel exhaust particles enhances coagulatory disturbance with endothelial damage and systemic inflammation related to lung inflammation

Presenter : , Inoue K., Yanagisawa R
Title : , Exp.Biol.Med., 231:1626-1632 (2006)
Effects of airway exposure to nanoparticles on lung inflammation induced by bacterial endotoxin in mice

Presenter : Hirano S., Takano H., Yanagisawa R, Inoue K.
Title : , Environ.Health Perspect., 114(9):1325-1330 (2006)
The role of toll-like receptor 4 in airway inflammation induced by diesel exhaust particles

Presenter : Inoue K., Takano H., Yanagisawa R., Hirano S., Ichinose T.(*1), Shimada A.(*2), Yoshikawa T.(*3)
Title : , Arch.Toxicol., 80:275-279 (2006)
Effects of organic chemicals derived from ambient particulate matter on lung inflammation related to lipopolysaccharide

Presenter : Inoue K., Takano H., Yanagisawa R., Hirano S., Kobayashi T., Ichinose T.(*1), Yoshikawa T.(*2)
Title : , Arch.Toxicol., 80:833-838 (2006)
Pulmonary toxicity induced by intratracheal instillation of Asian yellow dust(Kosa) in mice

Presenter : Ichinose T.(*1), Nishikawa M., Takano H., Sera N.(*2), Sadakane K.(*1), Mori I., Yanagisawa R., Oda T.(*3), Tamura H.(*3), Hiyoshi K.(*4)
Title : , Environ.Toxicol.Pharmacol., 20:48-56 (2005)
Prenatal exposure to bisphenol A upregulates immune responses,including T helper 1 and T helper 2 responses,in mice

Presenter : Yoshino S.(*1)(*2), Yamaki K.(*1), Xiaojuan Li.(*1), Sai T.(*2), Yanagisawa R., Takano H., Hayashi H.(*3)(*4), Mori Y.(*3)
Title : , Immunology, 112:489-495 (2004)
Complementary DNA microarray analysis in acute lung injury induced by lipopolysaccharide and diesel exhaust particles

Presenter : Yanagisawa R., Takano H., Inoue K., Ichinose T.(*1), Sadakane K.(*1), Yoshida S.(*1), Takeda K.(*2), Yoshino S.(*3), Yamaki K.(*3), Kumagai Y.(*4), Yoshikawa T.(*5)
Title : , Exp.Biol.Med., 229:1081-1087 (2004)
Effect of varying types of anti-arthritic drugs on Th1 and Th2 immune responses in mice

Presenter : Yamaki K(*1), Uchida H(*1), Li X(*1), Yanagisawa R., Takano H., Hayashi H.(*2), Mori Y.(*2), Yoshino S.(*1)
Title : , Int.J.Immunopathol.Pharmacol., 18:133-144 (2004)
Effects of the phosphodiesterase IV inhibitor rolipram on Th1 and Th2 immune responses in mice

Presenter : Yamaki K.(*1), Li X.(*1), Uchida H.(*1), Alam A.H.M.(*2), Hossain H.(*2), Yanagisawa R., Takano H., Hayashi H.(*3), Taneda S., Mori Y.(*3), Yoshino S.(*1)
Title : , J.Pharm.Pharmacol., 56:877-882 (2004)
A novel water-soluble vitamin e derivative prevents acute lung injury by bacterial endotoxin

Presenter : Uchiyama K.(*1), Takano H., Yanagisawa R., Inoue K., Naito Y.(*1), Yoshida N.(*1), Yoshino S.(*2), Murase H.(*3), Ichinose T.(*4), Yoshikawa T.(*1)
Title : , Clin.Exp.Pharmacol.Physiol, 31:226-230 (2004)
Nitrogen dioxide air pollution near ambient levels is an atherogenic risk primarily in obese subjects: a brief communication

Presenter : Takano H., Yanagisawa R., Inoue K., Shimada A.(*1), Ichinose T.(*2), Sadakane K.(*2), Yoshino S.(*3), Yamaki K.(*3), Morita M., Yoshikawa T.(*4)
Title : , Exp.Biol.Med., 229:361-364 (2004)
Protective role of metallothionein acute lung injury induced by bacterial endotoxin

Presenter : Takano H., Inoue K., Yanagisawa R., Sato M.(*1), Shimada A.(*2), Morita T., Sawada M.(*2), Nakamura K.(*2), Sanbongi C.(*3), Yoshikawa T.(*4)
Title : , Thorax, 59:1057-1062 (2004)
Rosmarinic acid in perilla extract inhibits allergic inflammation induced by mite allergen,in a mouse model

Presenter : Sanbongi C.(*1), Takano H., Osakabe N.(*1), Sasa N.(*1), Natsume M(*1), Yanagisawa R., Inoue K,.(*2), Sadakane K.(*3), Ichinose T.(*3), Yoshikawa T.(*2)
Title : , Clin.Exp.Allergy, 34:971-977 (2004)
Liver carcinogenesis and formation of 8-hydroxy-deoxyguanosine in C3H/HeN mice by oxidized dietary oils containing carcinogenic dicarbonyl compounds

Presenter : Ichinose T.(*1), Sera N.(*2), Takano H., Abe M.(*1), Sadakane K.(*1), Yanagisawa R., Ochi H.(*3), Fujioka K.(*4), Leee K-G.(*4), Shibamoto T.(*4)
Title : , Food Chem.Toxicol., 42:1795-1803 (2004)
Components of diesel exhaust particles differently affect lung expression of cyclooxygenase-2 related to bacterial endotoxin

Presenter : Inoue K., Takano H., Yanagisawa R., Ichinose T.(*1), Sadakane K.(*1), Yoshino S.(*2), Yamaki K.(*2), Uchiyama K.(*3), Yoshikawa T.(*3)
Title : , J.Appl.Toxicol., 24:415-418 (2004)
Protective role of interleukin-6 in coagulatory and hemostatic disturbance induced by lipopolysaccharide in mice

Presenter : , , Takano H., Inoue K., Yanagisawa R.
Title : , Thromb.Haemost., 91(6):1194-1201 (2004)
Statin,inflammation,and sepsis

Presenter : Takano H., Inoue K., Yanagisawa R.
Title : , Chest, 125(6):2365 (2004)
Surgical stress in ARDS open-lung biopsy

Presenter : Takano H., Inoue K., Yanagisawa R.
Title : , Chest, 126(4):1383 (2004)
Effect of 15-deoxy-delta(12,14)-prostaglandin J2 on acute lung injury induced by lipopolysaccharide in mice

Presenter : Inoue K., Takano H., Yanagisawa R., Morita M., Ichinose T.(*1), Sadakane K.(*1), Yoshino S.(*2), Yamaki K.(*2), Kumagai Y.(*3), Uchiyama K.(*4), Yoshikawa T.(*4)
Title : , Eur.J.Pharm., 481:261-269 (2003)
Diesel exhaust particles enhance lung injury related to bacterial endotoxin through expression of proinflammatory cytokines

Presenter : Takano H., Yanagisawa R., Ichinose T.(*1), Sadakane K.(*1), Yoshino S.(*2), Yoshikawa T.(*3), Morita M.
Title : , Am.J.Respir.Crit.Care Med., 165:1329-1335 (2002)
Lung expression of cytchrome P450 1A1 as a possible biomarker of exposure to diesel exhaust particles

Presenter : Takano H., Yanagisawa R., Ichinose T.(*1), Sadakane K.(*1), Inoue K.(*2), Yoshida S.(*3), Takeda K.(*3), Yoshino S.(*4), Yoshikawa T.(*2), Morita M.
Title : , Arch.Toxicol., 76:146-151 (2002)
Murine strain differences in airway inflammation induced by diesel exhaust particles and house dust mite allergen

Presenter : Sadakane K.(*1), Ichinose T.(*1), Takano H., Yanagisawa R., Sagai M.(*2), Yoshikawa T.(*3), Shibamoto T.(*4)
Title : , Int.Arch.Allergy Immunol., 128:220-228 (2002)
A novel water-soluble vitamin E derivative,2-(alpha-D-glucopyranosyl)methyl-2,5,7,8-tetramethylchroman-6-ol,protects against acute lung injury and mortality in endotoxemic rats

Presenter : Ochiai J.(*1), Takano H., Ichikawa H.(*1), Naito Y.(*1), Yoshida N.(*1), Yanagisawa R., Yoshino S.(*2), Murase H.(*3), Yoshikawa T.(*2)
Title : , Shock, 18(6):580-584 (2002)

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Dietary exposure to bisphenol A affects memory function and neuroimmune biomarkers in allergic asthmatic mice

Presenter : Tin-Tin-Win-Shwe, Yanagisawa R., Koike E., Takano H.
Title : , Journal of Applied Toxicology, 1-10 (2021)
The impact of oral exposure to low-dose tris(2-butoxyethyl)phosphate in allergic asthmatic mice

Presenter : Yanagisawa R., Koike E., Tin-Tin-Win-Shwe, Kawaguchi M., Takano H.
Title : , Journal of Applied Toxicology, 40(11):1498-1510 (2020)
Novel toxicity of tris(1,3-dichloro-2-propyl) phosphate in adult male rats

Presenter : Shohei Kobayashi, Kodai Abe, Anna Isobe, Airi Nakayama, Takahiro Akimoto, Taichi Hatakeyama, Yoshiaki Saito, Yanagisawa R., Koike E., Suzuki N., Maiko Kawaguchi, Ryo Ohta
Title : , Journal of Applied Toxicology, 1-6 (2020)
Toxicokinetics of methylmercury in diabetic KK-Ay mice and C57BL/6 mice

Presenter : Yamamoto M., Yanagisawa R., Sakai A., Mogi M., Shuto S., Shudo M., Kashiwagi H., Kudo M., Nakamura M., Sakamoto M.
Title : , Journal of Applied Toxicology, 1-13 (2020)
Decabromodiphenyl ether exacerbates hyperglycemia in diet-induced obese mice

Presenter : Yanagisawa R., Koike E., Tin-Tin-Win-Shwe, Hirohisa Takano
Title : , Toxicology, 15(412):12-18 (2019)
Hatano rats are a suitable metabolic syndrome model for studying feeding behavior, blood pressure levels, and percent body fat

Presenter : Isobe A., Shimada T., Aburada M., Yanagisawa R., Sakawa T., Nakamura T., Himi T., Ohta R., Kawaguchi M.
Title : , The Journal of Veterinary Medical Science, 81(1):147-154 (2019)
Memory function, neurological and immunological biomarkers in allergic asthmatic mice intratracheally exposed to bisphenol A

Presenter : Tin-Tin-Win-Shwe, Yanagisawa R., Koike E., Takano H
Title : , International Journal of Environmental Research and Public Health, 16(3770):1-16 (2019)
Oral exposure to low dose bisphenol A aggravates allergic airway inflammation in mice

Presenter : Yanagisawa R., Koike E., Tin-Tin-Win-Shwe, Hirohisa Takano
Title : , Toxicology Reports, 6:1253-1262 (2019)
Effects of lactational exposure to low-dose BaP on allergic and non-allergic immune responses in mice offspring

Presenter : Yanagisawa R., Koike E., Tin-Tin-Win-Shwe, Ichinose T., Takano H.
Title : , Journal of Immunotoxicology , 15(1):31-40 (2018)
Exposure to low-dose bisphenol A during the juvenile period of development disrupts the immune system and aggravates allergic airway inflammation in mice

Presenter : Koike E., Yanagisawa R., Tin-Tin-Win-Shwe, Takano H.
Title : , International Journal of Immunopathology and Pharmacology, 32:1-14 (2018)
Change over time of the mutagenicity in the lungs of gpt delta transgenic mice by extract of airborne particles collected from ambient air in the Tokyo metropolitan area

Presenter : Aoki Y., Nakajima D., Matsumoto M., Yagishita M., Matsumoto M., Yanagisawa R., Goto S., Masumura K., Nohmi T.
Title : , Genes and Environment, 40(25): (2018)
Evaluation of neurobehavioral impairment in methylmercury-treated KK-Ay mice by dynamic weight-bearing test

Presenter : Megumi Yamamoto, Eriko Motomura, Yanagisawa R., Van Anh Thi Hoang, Masaki Mogi, Tomohisa Mori, Masaaki Nakamura, Motohiro Takeya, Komyo Eto
Title : , Journal of Applied Toxicology, 39:221-230 (2018)
Activation of interleukin-6 and -8 expressions by methylmercury in human U937 macrophages involves RelA and p50

Presenter : Yamamoto M., Khan N., Muniroh M., Motomura E., Yanagisawa R., Matsuyama T., Vogel C.F.A.
Title : , Journal of Applied Toxicology, 37(5):611-620 (2017)
Brominated flame retardants, hexabromocyclododecane and tetrabromobisphenol A, affect proinflammatory protein expression in human bronchial epithelial cells via disruption of intracellular signaling

Presenter : Koike E., Yanagisawa R., Takano H.
Title : , Toxicology in Vitro, 32:212-219 (2016)
Low-dose benzo[a]pyrene aggravates allergic airway inflammation in mice

Presenter : Yanagisawa R., Koike E., Tin-Tin-Win-Shwe, Ichinose T., Takano H.
Title : , Journal of Applied Toxicology, 36:1496-1504 (2016)
Nano-Sized Secondary Organic Aerosol of Diesel Engine Exhaust Origin Impairs Olfactory-Based Spatial Learning Performance in Preweaning Mice

Presenter : Tin-Tin-Win-Shwe, Chaw Kyi Tha thu, Yadanar Moe, Maekawa F., Yanagisawa R., Furuyama A., Tsukahara, Fujitani Y., Hirano S.
Title : , Nanomaterials, 2015(5):1147-1162 (2015)
Penta- and octa-bromodiphenyl ethers promote proinflammatory protein expression in human bronchial epithelial cells in vitro

Presenter : Koike E., Yanagisawa R., Takigami H., Takano H.
Title : , Toxicology in Vitro, 28:327-333 (2014)
Impaired Lipid and Glucose Homeostasis in Hexabromocyclododecane-Exposed Mice Fed a High-Fat Diet

Presenter : Yanagisawa R., Koike E., Tin-Tin-Win-Shwe, Megumi Y., Takano H.
Title : , Environmental Health Perspectives, 122(3):277-283 (2014)
Toxicological effects of polycyclic aromatic hydrocarbons and their derivatives on respiratory cells

Presenter : Koike E., Yanagisawa R., Takano H.
Title : , Atmospheric Environment, 97:529-536 (2014)
Increased methylmercury toxicity related to obesity in diabetic KK-Ay mice

Presenter : Yamamoto M., Yanagisawa R., Motomura E., Nakamura M., Sakamoto M., Takeya M, Eto K.
Title : , Journal of Applied Toxicology, 34(8):914-923 (2014)
Effects of oral administration of di-(2-ethylhexyl) and diisononyl phthalates on atopic dermatitis in NC/Nga mice.

Presenter : Sadakane K., Ichinose T., Takano H., Yanagisawa R., Koike E.
Title : , Immunopharmacology and Immunotoxicology, 36(1):61-69 (2014)
Organic Chemicals in Diesel Exhaust Particles Enhance Picryl Chloride-Induced Atopic Dermatitis in NC/Nga Mice.

Presenter : Sadakane K., Ichinose T., Takano H., Yanagisawa R., Inoue KI., Kawazato H., Yasuda A., Hayakawa K.
Title : , International Archives of Allergy and Immunol.ogy, 162:7-15 (2013)
Expression levels of neuroimmune biomarkers in hypothalamus of allergic mice after phthalate exposure

Presenter : Tin-Tin-Win-Shwe, Yanagisawa R., Koike E., Nitta H., Takano H.
Title : , Journal of Applied Toxicology , 33(10):1071-1078 (2013)
Role of metallothionein in murine experimental colitis.

Presenter : Tsuji T., Naito Y., Takagi T., Kugai M., Yoriki H., Horie R., Fukui A., Mizushima K., Hirai Y., Katada K., Kamada K., Uchiyama K., Handa O., Konishi H., Yagi N., Ichikawa H., Yanagisawa R., Suzuki J., Takano H., Satoh M., Yoshikawa T.
Title : , International Journal of Molecular Medicine , 31(5):1037-1046 (2013)
Brominated flame retardants stimulate mouse immune cells in vitro

Presenter : Koike E., Yanagisawa R., Takigami H., Takano H.
Title : , Journal of applied toxicology , 33(12):1451-1459 (2013)
The alkylphenols 4-nonylphenol, 4-tert-octylphenol and 4-tert-butylphenol aggravate atopic dermatitis-like skin lesions in NC/Nga mice

Presenter : Sadakane K., Ichinose T., Takano H., Yanagisawa R., Koike E., Inoue K.
Title : , Journal of Applied Toxicology, 34(8):893-902 (2013)
Asian sand dust enhances murine lung inflammation caused by Klebsiella pneumoniae

Presenter : He M., Ichinose T., Yoshida S., Yamamoto S., Inoue Ken-ichiro, Takano H., Yanagisawa R., Nishikawa M., Mori I., Sun G., Shibamoto T.
Title : , Toxicology and Applied Pharmacology, 258(2):237-247 (2012)
Peroxiredoxin I null mice exhibits reduced acute lung inflammation following ozone exposure.

Presenter : Yanagisawa R., Warabi E., Inoue K., Yanagawa T., Koike E., Ichinose T., Takano H., Ishii T
Title : , The Journal of Biochemistry, 152(6):595-601 (2012)
Effects of diisononyl phthalate on atopic dermatitis in vivo and immunologic responses in vitro

Presenter : Koike E., Yanagisawa R., Sadakane K., Inoue Ken-ichiro, Ichinose T., Takano H.
Title : , Environ.Health Perspect., 118(4):472-478 (2010)
Size effects of polystyrene nanoparticles on atopic Dermatitis-Like skin lesions in NC/Nga mice

Presenter : Yanagisawa R., Takano H., Inoue Ken-ichiro, Koike E., Sadakane K., Ichinose T.
Title : , Int.J.Immunopathol.Pharmacol., 23(1):131-141 (2010)
Urban particulate matter in Beijing, China, enhances allergen-induced murine lung eosinophilia

Presenter : He M., Ichinose T., Yoshino S, Nishikawa M., Mori I., Yanagisawa R., Takano H., Inoue Ken-ichiro, Sun G., Shibamoto T.
Title : , Inhal.Toxicol., 22(9):709-718 (2010)
Extensive analysis of elastase-induced pulmonary emphysema in rats: ALP in the lung, a new biomarker for disease progression?

Presenter : Inoue Ken-ichiro, Koike E., Yanagisawa R., Takano H.
Title : , J.Clin.Biochem.Nutr., 46(2):168-176 (2010)
Size effects of latex nanomaterials on lung inflammation in mice

Presenter : Inoue Ken-ichiro, Takano H., Yanagisawa R., Koike E., Shimada A
Title : , Toxicol.Appl.Pharmacol., 234(1):68-76 (2009)
Effects of pulmonary exposure to diesel exhaust particles on extrathoracic CD4 polarization in asthmatic mice

Presenter : Inoue Ken-ichiro, Koike E., Yanagisawa R., Takano H.
Title : , Immunopharmacol.Immunotoxicol., 31(1):71-74 (2009)
Effects of diesel exhaust particles on antigen-presenting cells and antigen-specific Th immunity in mice

Presenter : Inoue Ken-ichiro, Koike E., Takano H., Yanagisawa R., Ichinose T., Yoshikawa T
Title : , Exp.Biol.Med., 234:200-209 (2009)
Titanium dioxide nanoparticles aggravate atopic dermatitis-like skin lesions in NC/Nga mice

Presenter : Yanagisawa R., Takano H., Inoue Ken-ichiro, Koike E., Kamachi T., Sadakane K., Ichinose T.
Title : , Exp.Biol.Med., 234:314-322 (2009)
Di-(2-ethylhexyl) phthalate affects immune cells from atopic prone mice in vitro

Presenter : Koike E., Inoue Ken-ichiro, Yanagisawa R., Takano H.
Title : , Toxicology, 259(1/2):54-60 (2009)
Peroxiredoxin ? is a negative regulator of Th2-dominant allergic asthma

Presenter : Inoue Ken-ichiro, Takano H., Koike E., Warabi E., Yanagawa T., Yanagisawa R., Ishii T.
Title : , Int.Immunopharmacol., 9(11):1281-1288 (2009)
Pulmonary exposure to soluble cell wall beta-(1, 3)-glucan of aspergillus induces proinflammatory response in mice

Presenter : Inoue Ken-ichiro, Koike E., Yanagisawa R., Adachi Y., Ishibashi K., Ohno N., Takano H.
Title : , Int.J.Immunopathol.Pharmacol., 22(2):287-297 (2009)
Effects of multi-walled carbon nanotubes on a murine allergic airway inflammation model

Presenter : Inoue Ken-ichiro, Koike E., Yanagisawa R., Hirano S., Nishikawa M., Takano H.
Title : , Toxicol.Appl.Pharmacol., 237(3):306-316 (2009)
Soluble cell wall β-glucan of candida induces/enhances apoposis and oxidative stress in murine lung

Presenter : Inoue Ken-ichiro, Takano H., Oda T., Yanagisawa R., Tamura H., Adachi Y., Ishibashi K., Ohno N.
Title : , Immunopharmacol.Immunotoxicol., 31(1):140-145 (2009)
Urinary trypsin inhibitor protects against liver injury and coagulation pathway dysregulation induced by lipopolysaccharide/D-galactosamine in mice

Presenter : Takano H., Inoue Ken-ichiro, Shimada A, Sato H., Yanagisawa R., Yoshikawa T
Title : , Lab.Invest., 89:833-839 (2009)
Pulmonary exposure to soluble cell wall β-(1, 3)-glucan of aspergillus induces proinflammatory response in mice

Presenter : Inoue Ken-ichiro, Koike E., Yanagisawa R., Adachi Y., Ishibashi K., Ohno N., Takano H.
Title : , Int.J.Immunopathol.Pharmacol., 22(2):287-297 (2009)
Candida soluble cell wall β-glucan facilitates ovalbumin-induced allergic airway inflammation in mice: Possible role of antigen-presenting cells

Presenter : Inoue Ken-ichiro, Takano H., Koike E., Yanagisawa R., Oda T., Tamura H., Adachi Y., Ishibashi K., Ohno N.
Title : , Respir.Res., 10(68):1-12 (2009)
Protective role of urinary trypsin in lung expression of proinflammatory cytokines accompanied by lethal liver injury in mice

Presenter : Inoue Ken-ichiro, Takano H., Sato H., Yanagisawa R., Yoshikawa T
Title : , Immunopharmacol.Immunotoxicol., 31(3):446-450 (2009)
Size effects of nanomaterials on lung inflammation and coagulatory disturbance

Presenter : Inoue Ken-ichiro, Takano H., Ohnuki M., Yanagisawa R., Sakurai M., Shimada A., Mizushima K., Toshikawa T.
Title : , Int.J.Immunopathol.Pharmacol., 21(1):197-206 (2008)
Pulmonary exposure to carbon black nanoparticles increases the number of antigen-presenting cells in murine lung

Presenter : Koike E., Takano H., Inoue Ken-ichiro, Yanagisawa R., Aoyagi H., Shinohara R., Kobayashi T.
Title : , Int.J.Immunopathol.Pharmacol., 21(1):35-42 (2008)
Effects of maternal exposure to Di-(2-ethylhexyl) phthalate during fetal and/or neonatal periods on atopic dermatitis in male offspring

Presenter : Yanagisawa R., Takano H., Inoue Ken-ichiro, Koike E., Sadakane.K, Ichinose.T
Title : , Environ.Health Perspect., 116(9):1136-1141 (2008)
Accelerated differentiation of bone marrow-derived dendritic cells in atopic prone mice

Presenter : Koike E., Takano H., Inoue Ken-ichiro, Yanagisawa R.
Title : , Int.Immunopharmacol., 8(-1314):1737-1743 (2008)
Role of metallothionein in lung inflammation induced by ozone exposure in mice

Presenter : Inoue Ken-ichiro, Takano H., Theerayuth Kaewamatawong, Shimada A, Suzuki J., Yanagisawa R., Tasaka S, Ishizaka A, Satoh M
Title : , Free Radical Biol.Med., 45(12):1714-1722 (2008)
Effects of pulmonary exposure to carbon nanotubes on lung and systemic inflammation with coagulatory disturbance induced by lipopolysaccharide in mice

Presenter : Inoue Ken-ichiro, Takano H., Koike E., Yanagisawa R., Tasaka S, Ishizaka A, Shimada A
Title : , Soc.Exp.Biol.Med., 233:1583-1590 (2008)
Antioxidative role of interleukin-6 in septic lung injury in mice

Presenter : Inoue Ken-ichiro, Takano H., Yanagisawa R., Shimada A, Satoh M, Yoshino S, Yamaki K, Yoshikawa T
Title : , Int.J.Immunopathol.Pharmacol., 21(3):501-507 (2008)
Impact of diesel exhaust particles on Th2 response in the lung in asthmatic mice

Presenter : Inoue Ken-ichiro, Koike E., Yanagisawa R., Takano H.
Title : , J.Clin.Biochem.Nutr., 43:199-200 (2008)
Carbon black nanoparticles promote the maturation and function of mouse bone marrow-derived dendritic cells

Presenter : Koike E., Takano H., Inoue Ken-ichiro, Yanagisawa R., Kobayashi T.
Title : , Chemosphere, 73(3):371-376 (2008)
Developmental exposure to pentachlorophenol affects the expression of thyroid hormone receptor β1 and synapsin ? in brain, resulting in thyroid function vulnerability in rats

Presenter : Kawaguchi M, Morohoshi K., Saita E., Yanagisawa R., Watanabe G., Takano H., Morita M., Imai H., Taya K., Himi T.
Title : , Endocrine, 33(3):277-284 (2008)
Cacao liquor proanthocyanidins inhibit lung injury induced by diesel exhaust particles

Presenter : Yasuda A., Takano H., Osakabe N., Sanbongi C., Fukuda K., Natsume M., Yanagisawa R., Inoue Ken-ichiro, Kato Y., Osawa T., Yoshikawa T
Title : , Int.J.Immunopathol.Pharmacol., 21(2):279-288 (2008)
Effects of Asian sand dust, Arizona sand dust, amorphous silica and aluminum oxide on allergic inflammation in the murine lung

Presenter : Ichinose T., Yoshida S., Sadakane K., Takano H., Yanagisawa R., Inoue Ken-ichiro, Nishikawa M., Mori I., Kawazato H., Yasuda A., Shibamoto T.
Title : , Inhal.Toxicol., 20(7):685-694 (2008)
Inhibition of the antigen-induced activation of RBL-2H3 cells by sinomenine

Presenter : Huang F., Yamaki K, Tong X., Fu L., Zhang R., Cai Y., Yanagisawa R., Inoue Ken-ichiro, Takano H., Yoshino S
Title : , Int.Immunopharmacol., 8(3):502-507 (2008)
Mutations in the lungs of gpt delta transgenic mice following inhalation of diesel exhaust

Presenter : Hashimoto A.H., Amanuma K., Hiyoshi K., Sugawara Y., Goto S., Yanagisawa R., Takano H., Masumura K., Nohmi T., Aoki Y.
Title : , Environ.Mol.Mutagen., 48(8):682-693 (2007)

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Airborne particles in pulmonary diseases

Presenter : Inoue Ken-ichiro, Takano H., Yanagisawa R., Yoshikawa T
Title : , Curr.Respir.Med.Rev., 5:69-72 (2009)
Protective effects of urinary trypsin inhibitor on systemic inflammatory response induced by lipopolysaccharide

Presenter : Inoue Ken-ichiro, Takano H., Yanagisawa R., Yoshikawa T
Title : , J.Clin.Biochem.Nutr., 43:139-142 (2008)

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Research Result (Presentation)

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Research Presentation
Research Lecture

Research Presentation
Dietary exposure to tris(1,3-dichloro-2-propyl) phosphate affects central nervous system in allergic asthmatic mice

Presenter : Tin-Tin-Win-Shwe, Yanagisawa R., Koike E., Takano H
Name of Society : 27th Japan Society of Immunotoxicology Meeting (2020)
Name of Proceedings : Abstract, 56-56
Research Presentation
Toxicological effects in adult male rats of two-hit exposure to tris(1,3-dichloro-2-propyl) phosphate (TDCIPP) at neonatal and adult stages

Presenter : Akimoto T., Kobayashi S., Hatakeyama T., Ohta R., Yanagisawa R., Koike E., Suzuki N., Kawaguchi M.
Name of Society : The 47th Annual Meeting of the Japanese Society of Toxicology (2020)
Name of Proceedings : -
Research Presentation
Exposure to flame retardant tris (2-butoxyethyl) phosphate induces memory deficit and neuroinflammatory responses in a mouse model of allergic asthma

Presenter : Tin-Tin-Win-Shwe, Yanagisawa R., Koike E., Takano H
Name of Society : 55th Congress of the European Societies of Toxicology (2019)
Name of Proceedings : Abstract, S213-S214
Research Presentation
Decabromodiphenyl ether impairs glucose homeostasis in mice fed a high-fat diet

Presenter : Yanagisawa R., Koike E., Tin-Tin-Win-Shwe
Name of Society : 15th International Congress of Toxicology (2019)
Name of Proceedings : Abstracts, 186
Research Presentation
Decabromodiphenyl ether affects immune response in obese mice and in adipocyte-macrophage co-culture system

Presenter : Koike E., Yanagisawa R., Tin-Tin-Win-Shwe, Takano H.
Name of Society : 15th International Congress of Toxicology (2019)
Name of Proceedings : Abstracts, 188
Research Presentation
Dietary exposure to flame retardant tris (2-butoxyethyl) phosphate alters cognitive function and inflammatory markers in brain of a mouse model of allergic asthma

Presenter : Tin-Tin-Win-Shwe, Yanagisawa R., Koike E., Takano H
Name of Society : The 41st Annual Meeting of the Japan Neuroscience Society (2018)
Name of Proceedings : Abstract, 242
Research Presentation
Oral exposure to bisphenol A impairs allergic asthma in mice

Presenter : Yanagisawa R., Koike E., Tin-Tin-Win-Shwe, Hirohisa Takano, Takano H.
Name of Society : The 67th Annual Meeting of Japanese Society of Allergology (2018)
Name of Proceedings : Japanese Journal of Allergology, 67(4.5):506
Research Presentation
Exposure to low-dose bisphenol A during the juvenile period of development disrupts the immune system and aggravates allergic airway inflammation in mice

Presenter : Koike E., Yanagisawa R., Tin-Tin-Win-Shwe, Takano H.
Name of Society : Joint Congress of the Asia Pacific Association of Allergy, Asthma and Clinical Immunology & the Asia Pacific Association of Pediatric Allergy, Respirology and Immunology (2018)
Name of Proceedings : - (mobile application)
Research Presentation
Effects of lactational exposure to low-dose benzo[a]pyrene on allergic airway inflammation in mice offspring

Presenter : Yanagisawa R., Koike E., Tin-Tin-Win-Shwe, Hirohisa Takano
Name of Society : The Joint Congress of the Asia Pacific Association of Allergy, Asthma and Clinical Immunology & the Asia Pacific Association of Pediatric Allergy, Respirology and Immunology (2018)
Name of Proceedings : -
Research Presentation
Exposure to bisphenol A on novel object recognition ability and neuroimmune biomarkers in allergic asthmatic mice

Presenter : Tin-Tin-Win-Shwe, Yanagisawa R., Koike E., Takano H
Name of Society : Asia Pacific Association of Allergy, Asthma and Immunology (APAAACI) (2018)
Name of Proceedings : Abstract P-23 (3rd day)
Research Presentation
Effects of exposure to bisphenol A on memory function and neuroimmune biomarkers in allergic asthmatic mice

Presenter : Tin-Tin-Win-Shwe, Yanagisawa R., Koike E., Takano H
Name of Society : 24th Annual Meeting of the Japanese Society of Immunotoxicology (2017)
Name of Proceedings : Abstracts, 84
Research Presentation
Lactational exposure to benzo[a]pyrene (BaP) on neuroimmune biomarkers in hippocampus of an allergic asthmatic mouse model

Presenter : Tin-Tin-Win-Shwe, Htike N.T.T., Tsukahara S., Koike E., Yanagisawa R.
Name of Society : The 39th Annual Meeting of the Japan neuroscience Society (2016)
Name of Proceedings : Abstract, 189
Research Presentation
Activation of IL-6 and IL-8 expression by methylmercury through NF-KB in human U937 macrophages

Presenter : Yamamoto M., Khan N., Muniroh M., Motomura E., Yanagisawa R., Matsuyama T., Vogel C.F.
Name of Society : 12th International Conference on Mercury as a Global Pollutant (2015)
Name of Proceedings : -
Research Presentation
Activation of IL-6 and IL-8 expression by methylmercury through NF-kB in human U937 macrophages

Presenter : Yamamoto M., Muniroh M., Khan N., Motomura E., Yanagisawa R., Matsuyama T., Vogel C.
Name of Society : The Society of Toxicology's 54th Annual Meeting (2015)
Name of Proceedings : 54th Annual Meeting and ToxExpo, 429-430
Research Presentation
Effects of developmental exposure to diesel engine exhaust origin secondary organic aerosol on social and learning behavior in adult mice

Presenter : Tin-Tin-Win-Shwe, Maekawa F., Chaw Kyi Tha Thu, Fujitani Y., Yanagisawa R., Furuyama A., Tsukahara S, Nohara K., Nitta H., Hirano S.
Name of Society : 37th Annual Meeting of the Japan Neuroscience Society (2014)
Name of Proceedings : Abstract, 131
Research Lecture
Proinflammatory Functions of Extracellular Peroxiredoxin 1 : A Case in Ozone Induced Acute Lung Inflammation in Mice

Presenter : Tetsuro Ishii, Eiji Warabi, Toru Yanagawa, Yanagisawa R.
Name of Society : 17th Biennial Meeting of Society for Free Radical Research International (2014)
Name of Proceedings : -
Research Presentation
NEUROTOXICITY IN ALLERGIC MICE AFTER EARLY PHTHALATE EXPOSURE

Presenter : Tin-Tin-Win-Shwe, Yanagisawa R., Koike E., Nitta H., Takano H.
Name of Society : International Conference of Asian Environmental Chemistry 2014 (2014)
Name of Proceedings : Abstract, 318
Research Presentation
Impact of hexabromocyclododecane on lipid and glucose metabolism in high-fat diet-induced obese mice

Presenter : YANAGISAWA Rie, TIN-TIN-Win-Shwe, KOIKE Eiko
Name of Society : 49th Congress of the European Societies of Toxicology (2013)
Name of Proceedings : Abstracts o the 49th Congress of the European Societies of Toxicology (EUROTOX), 221S:S252-S252
Research Presentation
Brominated flame retardants stimulate immune response in vitro

Presenter : Koike E., Yanagisawa R., Takano H
Name of Society : 49th Congress of the European Societies of Toxicology (2013)
Name of Proceedings : Toxicol. Lett. Abstracts o the 49th Congress of the European Societies of Toxicology (EUROTOX), 221S:S134-S134
Research Presentation
Expression of neuroimmune biomarkers in hypothalamus of allergic mice after early phthalate exposure

Presenter : Tin-Tin-Win-Shwe, Yanagisawa R., Koike E., Nakajima D., Takano H., Nitta H.
Name of Society : Annual Meeding of Society of Indoor Environment Japan 2012 (2012)
Name of Proceedings : Abstracts, 118-119
Research Presentation
Effects of maternal exposure to Di-(2-ethylhexyl) phthalate during fetal and/or neonatal periods on atopic dermatitis in male offspring

Presenter : Yanagisawa R., Takano H., Inoue Ken-ichiro, Koike E., Sadakane K., Ichinose T.
Name of Society : Int.Symp.Occup.Environ.Allerg.Immune Dis.2010(ISOEAID’10) (2010)
Name of Proceedings : Abstracts, 53
Research Presentation
Effects of Di-isononyl phthalate on atopic dermatitis in vivo and immunological responses in vitro

Presenter : Koike E., Yanagisawa R., Sadakane K., Inoue Ken-ichiro, Ichinose T., Takano H.
Name of Society : Int.Symp.Occup.Environ.Allerg.Immune Dis.2010(ISOEAID’10) (2010)
Name of Proceedings : Abstracts, 52
Research Presentation
In vivo mutagenicity of ambient air in the lungs of gpt delta transgenic mice;A case study in Tsukuba city,Japan

Presenter : Sato H. , Nakajima D., Kageyama S., Sakashita Y. , Yanagisawa R., Masumura K., Nohmi T., Aoki Y.
Name of Society : 2nd Asian Conf.Environ.Mutagens (2010)
Name of Proceedings : Abstracts
Research Presentation
Impacts of latex nanomaterials on sensitive lung inflammation

Presenter : Inoue Ken-ichiro, Takano H., Yanagisawa R., Koike E., Shimada A
Name of Society : HORIBA/CDBIM Symp. -21st Century Adv.Mol.Toxicol.Environ.Chem.Pathog.Dis.- (2009)
Name of Proceedings : Abstracts, 175
Research Presentation
Candida soluble cell wall β-D-glucan facilitates allergic lung inflammation via activation of antigen-presenting cells in mice

Presenter : Inoue Ken-ichiro, Takano H., Koike E., Yanagisawa R., Oda T, Tamura H, Adachi Y, Ishibashi K, Ohno N
Name of Society : 10th Int.Symp.Dendritic Cells (2008)
Name of Proceedings : Abstracts, 144
Research Presentation
Effects of diesel exhaust particles on antigen-presenting cells and antigen-specific Th2 immunity in mice

Presenter : Yanagisawa R., Inoue Ken-ichiro, Koike E., Takano H., Ichinose.T, Yoshino S, Yamaki K, Yoshikawa T
Name of Society : 10th Int.Symp.Dendritic Cells (2008)
Name of Proceedings : Abstracts, 142
Research Presentation
Microarray analysis of murine lungs following pulmonary exposure to diesel exhaust particles

Presenter : Yanagisawa R., Takano H., Koike E.
Name of Society : 47th Annu.Meet.ToxExpo(Poster Session) (2008)
Name of Proceedings : Program
Research Presentation
Exposure to carbon black nanoparticles activates antigen-presenting cells in vivo and in vitro

Presenter : Koike E., Yanagisawa R., Takano H.
Name of Society : 47th Annu.Meet.ToxExpo(Poster Session) (2008)
Name of Proceedings : Program
Research Presentation
Phthalate esters modulate the differentiation of mouse peripheral blood mononuclear cells-derived dendritic cells

Presenter : Ito T., Inoue Ken-ichiro, Koike E., Yanagisawa R., Nishimura N., Takano H.
Name of Society : 45th Congr.Eur.Soc.Toxicol. (2008)
Name of Proceedings : Toxicol.Lett., 180S:S117
Research Presentation
Low dose effects of phthalates and other environmental chemicals on atopic dermatitis-like skin lesions in mice

Presenter : Takano H., Yanagisawa R., Inoue Ken-ichiro., Koike E.
Name of Society : 2nd Workshop Low Dose Eff.Chem.Spec.Consideration Phthalates (2007)
Name of Proceedings : Abstracts
Research Presentation
In vivo mutations by 3,6-dinitrobenzo[e]pyrene instilled into the lung of gpt delta transgenic mice

Presenter : Matsumoto M., Takano H., Amanuma K., Yanagisawa R., Aoki Y.
Name of Society : 1st Asian Conf.Environ.Mutagens/36th Annu.Meet.Jpn.Environ.Mutagen Soc.(Poster Session) (2007)
Name of Proceedings : Program & Abstracts
Research Presentation
Elevation of blood glucose levels is prevented by intake of cacao liquor proanthocyanidins diabetic models

Presenter : Tomaru M.(*1), Takano H., Osakabe N.(*2), Yasuda A.(*2), Inoue K., Yanagisawa R., Uematsu H.(*2)
Name of Society : 18th Congr.Int.Assoc.Disability Oral Health (2006)
Name of Proceedings : Abstracts, 7(2)
Research Presentation
Enhancement of mite allergen-induced eosinophil infiltration in the murine airway and local cytokine/chemokine expression by Asian sand dust

Presenter : Ichinose T.(*1), Sadakane K.(*1), Takano H., Yanagisawa R., Nishikawa M., Mori I., Hiyoshi K.(*2), Shimizu H.
Name of Society : Int.Workshop Reg.Ecol.Environ.Eff. (2006)
Name of Proceedings : Abstracts
Research Presentation
In vivo mutagebusuty of diesel exhaust and its components,benzo[a]Pyrene and 1,6-dinitripyrene,in the lungs of gpt delta mice

Presenter : Aoki Y., Hashimoto A.H., Amanuma K., Hiyoshi K.(*1), Yanagisawa R., Takano H., Masumura K.(*2), Nohmi T.(*2)
Name of Society : 9th Int.Conf.Environ.Mutagens/36th Annu.Meet.Environ.Mutagen Soc. (2005)
Name of Proceedings : Abstracts
Research Presentation
Protective role of metallothionein in acute lung injury induced by bacterial endotoxin in mice

Presenter : Inoue K-i, Takano H., Yoshikawa T.(*1), Yanagisawa R., Sato M.(*2), Shimada A.(*3), Sawada M.(*3), Nakamura K.(*3), Sanbongi C.(*4), Tohyama C.
Name of Society : 8th Bienn.Conf.Int.Endotoxin Soc. (2004)
Name of Proceedings : Abstracts, 10(5)
Research Presentation
Protective role of IL-6 in pulmonary hemorrhage induced by bacterial endotoxin

Presenter : Inoue K-i., Takano H., Yanagisawa R., Sakurai M., Shimada A.(*1), Morita T., Sato M.(*2), Yoshino S.(*3), Yoshikawa T.(*4), Tohyama C.
Name of Society : 8th Int.Endotoxin Soc.Conf. (2004)
Name of Proceedings : Abstracts, 10(5)
Research Presentation
Components of diesel exhaust particles diversely enhance acute lung injury related to lipopolysaccharide

Presenter : Yanagisawa R., Takano H., Inoue K., Uchiyama K.(*1), Yoshikawa T.(*1)
Name of Society : 8th Bienn.Conf.Int.Endotoxin Soc. (2004)
Name of Proceedings : Abstracts, 10(5)
Research Presentation
Effects of components of diesel exhaust particles on systemic inflammatory respones related to acute lung injury in mice

Presenter : Yanagisawa R., Takano H.
Name of Society : 8th Bienn.Conf.Int.Endotoxin Soc. (2004)
Name of Proceedings : Abstracts, 10(5)

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Oral exposure to bisphenol A impairs allergic asthma in mice

Presenter : Yanagisawa R., Koike E., Tin-Tin-Win-Shwe, Hirohisa Takano, Takano H.
Name of Society : The 67th Annual Meeting of Japanese Society of Allergology (2018)
Name of Proceedings : Japanese Journal of Allergology, 67(4.5):506
Activation of IL-6 and IL-8 expression by methylmercury through NF-KB in human U937 macrophages

Presenter : Yamamoto M., Khan N., Muniroh M., Motomura E., Yanagisawa R., Matsuyama T., Vogel C.F.
Name of Society : 12th International Conference on Mercury as a Global Pollutant (2015)
Name of Proceedings : -
Expression of neuroimmune biomarkers in hypothalamus of allergic mice after early phthalate exposure

Presenter : Tin-Tin-Win-Shwe, Yanagisawa R., Koike E., Nakajima D., Takano H., Nitta H.
Name of Society : Annual Meeding of Society of Indoor Environment Japan 2012 (2012)
Name of Proceedings : Abstracts, 118-119
In vivo mutagenicity of ambient air in the lungs of gpt delta transgenic mice;A case study in Tsukuba city,Japan

Presenter : Sato H. , Nakajima D., Kageyama S., Sakashita Y. , Yanagisawa R., Masumura K., Nohmi T., Aoki Y.
Name of Society : 2nd Asian Conf.Environ.Mutagens (2010)
Name of Proceedings : Abstracts
Candida soluble cell wall β-D-glucan facilitates allergic lung inflammation via activation of antigen-presenting cells in mice

Presenter : Inoue Ken-ichiro, Takano H., Koike E., Yanagisawa R., Oda T, Tamura H, Adachi Y, Ishibashi K, Ohno N
Name of Society : 10th Int.Symp.Dendritic Cells (2008)
Name of Proceedings : Abstracts, 144
Microarray analysis of murine lungs following pulmonary exposure to diesel exhaust particles

Presenter : Yanagisawa R., Takano H., Koike E.
Name of Society : 47th Annu.Meet.ToxExpo(Poster Session) (2008)
Name of Proceedings : Program
Exposure to carbon black nanoparticles activates antigen-presenting cells in vivo and in vitro

Presenter : Koike E., Yanagisawa R., Takano H.
Name of Society : 47th Annu.Meet.ToxExpo(Poster Session) (2008)
Name of Proceedings : Program
Low dose effects of phthalates and other environmental chemicals on atopic dermatitis-like skin lesions in mice

Presenter : Takano H., Yanagisawa R., Inoue Ken-ichiro., Koike E.
Name of Society : 2nd Workshop Low Dose Eff.Chem.Spec.Consideration Phthalates (2007)
Name of Proceedings : Abstracts
In vivo mutations by 3,6-dinitrobenzo[e]pyrene instilled into the lung of gpt delta transgenic mice

Presenter : Matsumoto M., Takano H., Amanuma K., Yanagisawa R., Aoki Y.
Name of Society : 1st Asian Conf.Environ.Mutagens/36th Annu.Meet.Jpn.Environ.Mutagen Soc.(Poster Session) (2007)
Name of Proceedings : Program & Abstracts
Elevation of blood glucose levels is prevented by intake of cacao liquor proanthocyanidins diabetic models

Presenter : Tomaru M.(*1), Takano H., Osakabe N.(*2), Yasuda A.(*2), Inoue K., Yanagisawa R., Uematsu H.(*2)
Name of Society : 18th Congr.Int.Assoc.Disability Oral Health (2006)
Name of Proceedings : Abstracts, 7(2)
Enhancement of mite allergen-induced eosinophil infiltration in the murine airway and local cytokine/chemokine expression by Asian sand dust

Presenter : Ichinose T.(*1), Sadakane K.(*1), Takano H., Yanagisawa R., Nishikawa M., Mori I., Hiyoshi K.(*2), Shimizu H.
Name of Society : Int.Workshop Reg.Ecol.Environ.Eff. (2006)
Name of Proceedings : Abstracts
In vivo mutagebusuty of diesel exhaust and its components,benzo[a]Pyrene and 1,6-dinitripyrene,in the lungs of gpt delta mice

Presenter : Aoki Y., Hashimoto A.H., Amanuma K., Hiyoshi K.(*1), Yanagisawa R., Takano H., Masumura K.(*2), Nohmi T.(*2)
Name of Society : 9th Int.Conf.Environ.Mutagens/36th Annu.Meet.Environ.Mutagen Soc. (2005)
Name of Proceedings : Abstracts
Protective role of metallothionein in acute lung injury induced by bacterial endotoxin in mice

Presenter : Inoue K-i, Takano H., Yoshikawa T.(*1), Yanagisawa R., Sato M.(*2), Shimada A.(*3), Sawada M.(*3), Nakamura K.(*3), Sanbongi C.(*4), Tohyama C.
Name of Society : 8th Bienn.Conf.Int.Endotoxin Soc. (2004)
Name of Proceedings : Abstracts, 10(5)
Protective role of IL-6 in pulmonary hemorrhage induced by bacterial endotoxin

Presenter : Inoue K-i., Takano H., Yanagisawa R., Sakurai M., Shimada A.(*1), Morita T., Sato M.(*2), Yoshino S.(*3), Yoshikawa T.(*4), Tohyama C.
Name of Society : 8th Int.Endotoxin Soc.Conf. (2004)
Name of Proceedings : Abstracts, 10(5)
Components of diesel exhaust particles diversely enhance acute lung injury related to lipopolysaccharide

Presenter : Yanagisawa R., Takano H., Inoue K., Uchiyama K.(*1), Yoshikawa T.(*1)
Name of Society : 8th Bienn.Conf.Int.Endotoxin Soc. (2004)
Name of Proceedings : Abstracts, 10(5)
Effects of components of diesel exhaust particles on systemic inflammatory respones related to acute lung injury in mice

Presenter : Yanagisawa R., Takano H.
Name of Society : 8th Bienn.Conf.Int.Endotoxin Soc. (2004)
Name of Proceedings : Abstracts, 10(5)
Dietary exposure to tris(1,3-dichloro-2-propyl) phosphate affects central nervous system in allergic asthmatic mice

Presenter : Tin-Tin-Win-Shwe, Yanagisawa R., Koike E., Takano H
Name of Society : 27th Japan Society of Immunotoxicology Meeting (2020)
Name of Proceedings : Abstract, 56-56
Toxicological effects in adult male rats of two-hit exposure to tris(1,3-dichloro-2-propyl) phosphate (TDCIPP) at neonatal and adult stages

Presenter : Akimoto T., Kobayashi S., Hatakeyama T., Ohta R., Yanagisawa R., Koike E., Suzuki N., Kawaguchi M.
Name of Society : The 47th Annual Meeting of the Japanese Society of Toxicology (2020)
Name of Proceedings : -
Exposure to flame retardant tris (2-butoxyethyl) phosphate induces memory deficit and neuroinflammatory responses in a mouse model of allergic asthma

Presenter : Tin-Tin-Win-Shwe, Yanagisawa R., Koike E., Takano H
Name of Society : 55th Congress of the European Societies of Toxicology (2019)
Name of Proceedings : Abstract, S213-S214
Decabromodiphenyl ether impairs glucose homeostasis in mice fed a high-fat diet

Presenter : Yanagisawa R., Koike E., Tin-Tin-Win-Shwe
Name of Society : 15th International Congress of Toxicology (2019)
Name of Proceedings : Abstracts, 186
Decabromodiphenyl ether affects immune response in obese mice and in adipocyte-macrophage co-culture system

Presenter : Koike E., Yanagisawa R., Tin-Tin-Win-Shwe, Takano H.
Name of Society : 15th International Congress of Toxicology (2019)
Name of Proceedings : Abstracts, 188
Dietary exposure to flame retardant tris (2-butoxyethyl) phosphate alters cognitive function and inflammatory markers in brain of a mouse model of allergic asthma

Presenter : Tin-Tin-Win-Shwe, Yanagisawa R., Koike E., Takano H
Name of Society : The 41st Annual Meeting of the Japan Neuroscience Society (2018)
Name of Proceedings : Abstract, 242
Exposure to low-dose bisphenol A during the juvenile period of development disrupts the immune system and aggravates allergic airway inflammation in mice

Presenter : Koike E., Yanagisawa R., Tin-Tin-Win-Shwe, Takano H.
Name of Society : Joint Congress of the Asia Pacific Association of Allergy, Asthma and Clinical Immunology & the Asia Pacific Association of Pediatric Allergy, Respirology and Immunology (2018)
Name of Proceedings : - (mobile application)
Effects of lactational exposure to low-dose benzo[a]pyrene on allergic airway inflammation in mice offspring

Presenter : Yanagisawa R., Koike E., Tin-Tin-Win-Shwe, Hirohisa Takano
Name of Society : The Joint Congress of the Asia Pacific Association of Allergy, Asthma and Clinical Immunology & the Asia Pacific Association of Pediatric Allergy, Respirology and Immunology (2018)
Name of Proceedings : -
Exposure to bisphenol A on novel object recognition ability and neuroimmune biomarkers in allergic asthmatic mice

Presenter : Tin-Tin-Win-Shwe, Yanagisawa R., Koike E., Takano H
Name of Society : Asia Pacific Association of Allergy, Asthma and Immunology (APAAACI) (2018)
Name of Proceedings : Abstract P-23 (3rd day)
Effects of exposure to bisphenol A on memory function and neuroimmune biomarkers in allergic asthmatic mice

Presenter : Tin-Tin-Win-Shwe, Yanagisawa R., Koike E., Takano H
Name of Society : 24th Annual Meeting of the Japanese Society of Immunotoxicology (2017)
Name of Proceedings : Abstracts, 84
Lactational exposure to benzo[a]pyrene (BaP) on neuroimmune biomarkers in hippocampus of an allergic asthmatic mouse model

Presenter : Tin-Tin-Win-Shwe, Htike N.T.T., Tsukahara S., Koike E., Yanagisawa R.
Name of Society : The 39th Annual Meeting of the Japan neuroscience Society (2016)
Name of Proceedings : Abstract, 189
Activation of IL-6 and IL-8 expression by methylmercury through NF-kB in human U937 macrophages

Presenter : Yamamoto M., Muniroh M., Khan N., Motomura E., Yanagisawa R., Matsuyama T., Vogel C.
Name of Society : The Society of Toxicology's 54th Annual Meeting (2015)
Name of Proceedings : 54th Annual Meeting and ToxExpo, 429-430
Effects of developmental exposure to diesel engine exhaust origin secondary organic aerosol on social and learning behavior in adult mice

Presenter : Tin-Tin-Win-Shwe, Maekawa F., Chaw Kyi Tha Thu, Fujitani Y., Yanagisawa R., Furuyama A., Tsukahara S, Nohara K., Nitta H., Hirano S.
Name of Society : 37th Annual Meeting of the Japan Neuroscience Society (2014)
Name of Proceedings : Abstract, 131
NEUROTOXICITY IN ALLERGIC MICE AFTER EARLY PHTHALATE EXPOSURE

Presenter : Tin-Tin-Win-Shwe, Yanagisawa R., Koike E., Nitta H., Takano H.
Name of Society : International Conference of Asian Environmental Chemistry 2014 (2014)
Name of Proceedings : Abstract, 318
Impact of hexabromocyclododecane on lipid and glucose metabolism in high-fat diet-induced obese mice

Presenter : YANAGISAWA Rie, TIN-TIN-Win-Shwe, KOIKE Eiko
Name of Society : 49th Congress of the European Societies of Toxicology (2013)
Name of Proceedings : Abstracts o the 49th Congress of the European Societies of Toxicology (EUROTOX), 221S:S252-S252
Brominated flame retardants stimulate immune response in vitro

Presenter : Koike E., Yanagisawa R., Takano H
Name of Society : 49th Congress of the European Societies of Toxicology (2013)
Name of Proceedings : Toxicol. Lett. Abstracts o the 49th Congress of the European Societies of Toxicology (EUROTOX), 221S:S134-S134
Effects of maternal exposure to Di-(2-ethylhexyl) phthalate during fetal and/or neonatal periods on atopic dermatitis in male offspring

Presenter : Yanagisawa R., Takano H., Inoue Ken-ichiro, Koike E., Sadakane K., Ichinose T.
Name of Society : Int.Symp.Occup.Environ.Allerg.Immune Dis.2010(ISOEAID’10) (2010)
Name of Proceedings : Abstracts, 53
Effects of Di-isononyl phthalate on atopic dermatitis in vivo and immunological responses in vitro

Presenter : Koike E., Yanagisawa R., Sadakane K., Inoue Ken-ichiro, Ichinose T., Takano H.
Name of Society : Int.Symp.Occup.Environ.Allerg.Immune Dis.2010(ISOEAID’10) (2010)
Name of Proceedings : Abstracts, 52
Impacts of latex nanomaterials on sensitive lung inflammation

Presenter : Inoue Ken-ichiro, Takano H., Yanagisawa R., Koike E., Shimada A
Name of Society : HORIBA/CDBIM Symp. -21st Century Adv.Mol.Toxicol.Environ.Chem.Pathog.Dis.- (2009)
Name of Proceedings : Abstracts, 175
Effects of diesel exhaust particles on antigen-presenting cells and antigen-specific Th2 immunity in mice

Presenter : Yanagisawa R., Inoue Ken-ichiro, Koike E., Takano H., Ichinose.T, Yoshino S, Yamaki K, Yoshikawa T
Name of Society : 10th Int.Symp.Dendritic Cells (2008)
Name of Proceedings : Abstracts, 142
Phthalate esters modulate the differentiation of mouse peripheral blood mononuclear cells-derived dendritic cells

Presenter : Ito T., Inoue Ken-ichiro, Koike E., Yanagisawa R., Nishimura N., Takano H.
Name of Society : 45th Congr.Eur.Soc.Toxicol. (2008)
Name of Proceedings : Toxicol.Lett., 180S:S117

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Proinflammatory Functions of Extracellular Peroxiredoxin 1 : A Case in Ozone Induced Acute Lung Inflammation in Mice

Presenter : Tetsuro Ishii, Eiji Warabi, Toru Yanagawa, Yanagisawa R.
Name of Society : 17th Biennial Meeting of Society for Free Radical Research International (2014)
Name of Proceedings : -

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YANAGISAWA Rie

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