Latest Update：2026/03/24 10:41:40

YAMAGISHI Takahiro

Researcher Name: YAMAGISHI Takahiro

Div (Section) name/title: Health and Environmental Risk Division（Research Office for Environmental Risk Science）／Chief Senior Researcher

Research Subject

Fiscal Year: 2025
- 27217 : Research project on the ecological impact and factor analysis considering vulnerability
- 27392 : Assessment of effects on marine organisms exposed to microplastics via water and sediment
- 27419 : Developing a water quality health assessment system for offshore exploitation sites
- 27510 : Fundamental study for environmental risk assessment
- 27512 : The study for establishing a new fish acute toxicity test concerning animal welfare
- 27513 : Fundamental study for standardization of ecotoxicity
- 27514 : Development of novel bioassay technique
- 27559 : Impact assessment of antimicrobial residues on the aquatic ecosystem
- 27560 : Profile analysis of ecotoxicity of bioplastic eluates using marine organisms
- 27561 : FY2025 Contract work on the development and validation of new ecotoxicity test methods in OECD and the support for GLP inspection activities
- 27562 : FY2025 Contract work on test method development for endocrine disrupting chemicals
- 27571 : Study on risk assessment of chemicals using effect directed analysis in FY2025
- 27580 : Contract study on the ecological risk assessment of multiple chemicals in FY2025
- 27581 : FY2025 Contract research work on the development of new assessment method for ecological risk of pesticides and optimization of risk assessment
Fiscal Year: 2024
- 26831 : Research project on the ecological impact and factor analysis considering vulnerability
- 26945 : Developing a water quality health assessment system for offshore exploitation sites
- 27002 : Development of ecological risk assessment methods for multiple chemicals based on the similarity of activity/structure and exposure profile
- 27038 : Assessment of effects on marine organisms exposed to microplastics via water and sediment
- 27041 : FY2024 Contract work on the development and validation of new ecotoxicity test methods in OECD and the support for GLP inspection activities
- 27077 : The study for establishing a new fish acute toxicity test concerning animal welfare
- 27078 : Fundamental study for standardization of ecotoxicity
- 27079 : Development of novel bioassay technique
- 27131 : FY2024 Contract work on test method development for endocrine disrupting chemicals
- 27132 : Study on risk assessment of chemicals using effect directed analysis in FY2024
- 27134 : Fundamental study for environmental risk assessment
- 27360 : Contract study on the ecological risk assessment of multiple chemicals in FY2024
- 27361 : FY2024 Contract research work on the development of new assessment method for ecological risk of pesticides
- 27411 : Profile analysis of ecotoxicity of bioplastic eluates using marine organisms
- 27412 : Research on utilization of bioassays for management of various water environments
Fiscal Year: 2023
- 26421 : Research project on the ecological impact and factor analysis considering vulnerability
- 26529 : Fundamental study for environmental risk assessment
- 26716 : Development of ecological risk assessment methods for multiple chemicals based on the similarity of activity/structure and exposure profile
- 26717 : Profile analysis of ecotoxicity of bioplastic eluates using marine organisms
- 26718 : Study on development of framework for environmental risk assessment of new pharmaceuticals by integrated approaches to testing and assessment (IATA)
- 26719 : Research on utilization of bioassays for management of various water environments
- 26720 : FY2023 Contract work on the development and validation of new ecotoxicity test methods in OECD and the support for GLP inspection activities
- 26725 : Developing a water quality health assessment system for offshore exploitation sites
- 26755 : FY2023 Contract work on test method development for endocrine disrupting chemicals
- 26756 : FY2023 Contract research work on the development of new assessment method for ecological risk of pesticides
- 26757 : Study on risk assessment of chemicals using effect directed analysis in FY2023
- 26768 : Contract study on the ecotoxicity testing for the development of assessment of chemical mixtures in FY2022
- 26769 : Assessment of effects on marine organisms exposed to microplastics via water and sediment
- 26793 : The study for establishing a new fish acute toxicity test concerning animal welfare
- 26794 : Fundamental study for standardization of ecotoxicity
- 26795 : Development of novel bioassay technique
Fiscal Year: 2022
- 25974 : Research project on the ecological impact and factor analysis considering vulnerability
- 26276 : Fundamental study for environmental risk assessment
- 26278 : Fundamental study for standardization of ecotoxicity
- 26279 : Development of novel bioassay technique
- 26298 : FY2021-2022 Tier 2 Testing for endocrine disrupting chemical (17β-estradiol)
- 26323 : Investigation toward the development of a non-destructive evaluation method for fish toxicity using environmental RNA
- 26337 : Development of ecological risk assessment methods for multiple chemicals based on the similarity of activity/structure and exposure profile
- 26338 : FY2022 Contract work on test method development for endocrine disrupting chemicals
- 26339 : FY2022 Contract work on the development and validation of new ecotoxicity test methods in OECD and the support for GLP inspection activities
- 26340 : Profile analysis of ecotoxicity of bioplastic eluates using marine organisms
- 26357 : Study on development of framework for environmental risk assessment of new pharmaceuticals by integrated approaches to testing and assessment (IATA)
- 26396 : Study on risk assessment of chemicals using effect directed analysis in FY2022
- 26397 : Contract study on the ecotoxicity testing for the development of assessment of chemical mixtures in FY2022
- 26398 : FY2022 Contract research work on the development of new assessment method for ecological risk of pesticides
- 26399 : Research on utilization of bioassays for management of various water environments
Fiscal Year: 2021
- 25518 : Study on ecological impact and factor analysis considering vulnerability
- 25879 : Study on species sensitive distribution (SSD) based on the difference of somatotype of aquatic plants
- 25882 : Development of the prediction system for environmental effects by new drugs based on the evaluation results of environmental toxicity by existing drugs
- 25883 : Comparison of various bioassay for testing water quality of ambient water samples
- 25886 : Fundamental study for environmental risk assessment
- 25887 : Fundamental study for standardization of ecotoxicity
- 25890 : Development of novel bioassay technique
- 25892 : FY2021 Contract work on test method development for endocrine disrupting chemicals
- 25895 : FY2021 Contract work on the development and validation of new ecotoxicity test methods in OECD
- 25897 : FY2021 Contract research work on the development of new assessment method for ecological risk of pesticides
- 25927 : Study on practical assessment technique for marine environment during seafloor mineral mining
- 25938 : Study on risk assessment of chemicals using effect directed analysis in FY2021
- 25942 : Study on the ecotoxicity testing for the development of assessment of chemical mixtures in FY2021
- 25943 : FY2021-2022 Tier 2 Testing for endocrine disrupting chemical (17β-estradiol)
Fiscal Year: 2020
- 25099 : Research Program on Health and Environmental Safety
- 25124 : Risk Assessment Science Collaboration Office
- 25144 : Project to Build a System Evaluating Ecological Effect Comprehensively and Effectively
- 25359 : Study on practical assessment technique for marine environment during seafloor mineral mining
- 25362 : Comparison of various bioassay for testing water quality of ambient water samples
- 25363 : Development of the prediction system for environmental effects by new drugs based on the evaluation results of environmental toxicity by existing drugs
- 25364 : FY2019-2020 Tier 2 Testing for endocrine disrupting chemical (17α-ethynylestradiol)
- 25365 : Upgrade of Ecotoxicity Testing and Development of Novel System to Evaluate Ecotoxicological Effects of Chemicals
- 25366 : Development of short-term chronic toxicity tests using marine and estuarine species
- 25401 : Study on revision of OECD fish, acute toxicity testing
- 25407 : The development of new ecological risk assessment method for agricultural chemicals
- 25410 : Study on species sensitive distribution (SSD) based on the difference of somatotype of aquatic plants
Fiscal Year: 2019
- 24696 : Research Program on Health and Environmental Safety
- 24724 : Project to Build a System Evaluating Ecological Effect Comprehensively and Effectively
- 24756 : Risk Assessment Science Collaboration Office
- 24929 : Analysis of gene mutation in green alga Pseudokirchneriella subcapitata among algal culture collections
- 24930 : The study of impacts of chelating agents on algal species
- 25020 : Upgrade of Ecotoxicity Testing and Development of Novel System to Evaluate Ecotoxicological Effects of Chemicals
- 25021 : Development of short-term chronic toxicity tests using marine and estuarine species
- 25022 : FY2019 Validation research on the amendment of the OECD fish acute toxicity test guideline
- 25050 : Development of the prediction system for environmental effects by new drugs based on the evaluation results of environmental toxicity by existing drugs
- 25051 : Comparison of various bioassay for testing water quality of ambient water samples
- 25052 : Study on practical assessment technique for marine environment during seafloor mineral mining
- 25091 : FY2019 Study on the Development of Assessment Procedure for the Mixture Effects of Chemicals Using Ecotoxicity Testing
- 25092 : FY2019 Contract research work on risk assessment of chemicals using the effect-directed analysis
- 25093 : FY2019 Development of Testing Methods Regarding Endocrine Disrupting Effects of Chemicals
- 25094 : FY2019-2020 Tier 2 Testing for endocrine disrupting chemical (17α-ethynylestradiol)
- 25095 : FY2019 Research on the development of novel methods for the assessment of ecological risk of pesticides in aquatic environment
Fiscal Year: 2018
- 24307 : Project to build a system evaluating ecological effect comprehensively and effectively
- 24339 : Risk Assessment Science Collaboration Office
- 24355 : Research program on health and environmental safety
- 24533 : Case study on biological risk in aquatic environment using WET method
- 24534 : FY2017-2018 Tier 2 Biological Tests Regarding Chemicals with Endocrine Disrupting Effects
- 24535 : FY2018 Development of Testing Methods Regarding Endocrine Disrupting Effects of Chemicals
- 24536 : FY2018 Study on the Development of Assessment Procedure for the Mixture Effects of Chemicals Using Ecotoxicity Testing
- 24538 : Development of short-term chronic toxicity tests using marine and estuarine species
Fiscal Year: 2017
- 24066 : Research and Development of Monitoring and Forecasting Systems for Marine Ecosystem Management
- 24184 : FY2017 Development of Testing Methods Regarding Endocrine Disrupting Effects of Chemicals
- 24185 : FY2017-2018 Tier 2 Biological Tests Regarding Chemicals with Endocrine Disrupting Effects
Fiscal Year: 2016
- 23683 : Research and Development of Monitoring and Forecasting Systems for Marine Ecosystem Management
- 23702 : Risk Assessment Science Collaboration Office Ecotoxicity Reference Laboratory

View all

Research Result (Publication)

Original Paper

Ecotoxicity assessment of phthalic acid di-alkyl ester mixtures toward aquatic organisms based on results from a series of subchronic toxicity tests

Presenter : Oda Y., Kawano M., Watanabe H., Yamagishi T., Yamamoto H.
Title : , Environmental Toxicology and Chemistry (2025)
Original Paper

Polyethylene microbead distribution in sediment toxicity test system with estuarine amphipod Grandidierella japonica

Presenter : Hiki K., Namba N,, Watanabe H., Yamagishi T., Yamamoto H.
Title : , Environmental Toxicology and Chemistry, 44(11):3086-3094 (2025)
Original Paper

Prediction of chronic toxicity of pharmaceuticals in Daphnia magna by combining ortholog prediction, pharmacological effects, and quantitative structure-activity relationship

Presenter : Ninomiya Y., Watanabe H., Yamagishi T., Maruyama-Komoda T., Yamada T., Yamamoto H.
Title : , Ecotoxicology and Environmental Safety, 282(116737): (2024)
Original Paper

Development of a microplate-based novel toxicity bioassay using Chlorophyta and Phaeophyceae macroalgae

Presenter : Onduka T., Somiya R., Yamagishi T., Hano T., Yamamoto H., Mochida K.
Title : , Ecotoxicology (2023)
Original Paper

Environmental RNA as a Noninvasive Tool for Assessing Toxic Effects in Fish: A Proof-of-concept Study Using Japanese Medaka Exposed to Pyrene

Presenter : Hiki K., Yamagishi T., Yamamoto H.
Title : , Environmental Science & Technology, 57(34):12654-12662 (2023)
Other Publications

The complete mitochondrial genome of water flea Ceriodaphnia dubia (Crustacea: Cladocera) NIES strain

Presenter : Hiki K., Oka K., Nakajima N., Watanabe H., Yamamoto H., Yamagishi T.
Title : , Mitochondrial DNA Part B: Resources, 8(8):831-835 (2023)
Original Paper

Potential differences in chitin synthesis ability cause different sensitivities to diflubenzuron among three strains of Daphnia magna

Presenter : KATO K., Okamura K., Hiki K., Kintsu H., Nohara K., Yamagishi T., Nakajima N., Watanabe H., Yamamoto H.
Title : , Aquatic Toxicology, 243(106071): (2022)
Original Paper

Severity classification of clinical signs and defining the moribund state as an experimental endpoint for acute toxicity testing using Japanese medaka (Oryzias latipes)

Presenter : Yamagishi T., Kawano M., Watanabe H., Yagi A., Shintaku Y., Ohno K., Yamamoto H.
Title : , Environmental Toxicology and Chemistry, 41(4):1089-1095 (2022)
Original Paper

Propidium iodide staining and flow cytometry-based assessment of heavy metal impact on marine phytoplankton

Presenter : Ota S., Fuchida S., Yamaguchi H., Yamagishi T., Yamamoto H., Koshikawa H., Kawachi M.
Title : , Cytologia, 87(2):177-187 (2022)
Original Paper

Rapid transcriptomic and physiological changes in the freshwater pennate diatom Mayamaea pseudoterrestris in response to copper exposure

Presenter : Suzuki S., Ota S., Yamagishi T., Tuji A., Yamaguchi H., Kawachi M.
Title : , DNA Research, 29(6):1-12 (2022)
Original Paper

Toxicity assessment of typical polycyclic aromatic hydrocarbons to Daphnia magna and Hyalella azteca in water-only and sediment-water exposure systems

Presenter : Tani K., Watanabe H., Noguchi M., Hiki K., Yamagishi T., Yamamoto H.
Title : , Science of the Total Environment, 784(147156): (2021)
Other Publications

Acute Toxicity of a Tire Rubber-Derived Chemical, 6PPD Quinone, to Freshwater Fish and Crustacean Species

Presenter : Hiki K., Asahina K., KATO K., Yamagishi T., Omagari R., Iwasaki Y., Watanabe H., Yamamoto H.
Title : , Environmental Science & Technology Letters, 8(9):779-784 (2021)
Original Paper

Alternative Diatom Strains for Growth Inhibition Tests (OECD Test Guideline 201)

Presenter : Tuji A., Suzuki S., Yamagishi T., Yamaguchi H.
Title : , Bull. Natl. Mus. Nat. Sci., Ser. B, 47(4):1-10 (2021)
Other Publications

The complete mitochondrial genome of the non-biting midge Chironomus yoshimatsui (Diptera: Chironomidae)

Presenter : Hiki K., Oka K., Nakajima N., Yamamoto H., Yamagishi T., Sugaya Y.
Title : , Mitochondrial DNA Part B, 6(10):2995-2996 (2021)
Original Paper

Differential heavy metal sensitivity in seven algal species from the NIES culture collection based on delayed fluorescence assays

Presenter : Ota S., Yamaguchi H., Vanel F., Fuchida S., Koshikawa H., Yamagishi T., Yamamoto H., Kawachi M.
Title : , Phycological Research, 68(1):41-49 (2020)
Original Paper

Comparative genome analysis of test algal strain NIVA-CHL1 (Raphidocelis subcapitata) maintained in microalgal culture collections worldwide

Presenter : Yamagishi T., Yamaguchi H., Suzuki S., Yoshikawa M. , Jameson I., Lorenz M., Nobles D.R., Campbell C., Seki M., Kawachi M., Yamamoto H.
Title : , PLOS ONE, 15(11):e0241889 (2020)
Book

Ecotoxicological Bioassay Using Marine Algae for Deep-Sea Mining

Presenter : Yamagishi T., Ota S., Yamaguchi H., Koshikawa H., Tatarazako, N., Yamamoto H., Kawachi M.
Title : , Environmental Issues of Deep-Sea Mining: Impacts, Consequences and Policy Perspectives (2019)
Other Publications

Evaluation of the toxicity of leaches from hydrothermal sulfide deposits by means of a delayed fluorescence-based bioassay with the marine cyanobacterium Cyanobium sp. NIES-981

Presenter : Yamagishi T., Fuchida S., Katsumata M, Horie Y, Mori F., Kawachi M., Koshikawa H., Nozaki T., Kumagai H., Ishibasi J., Tatarazako N
Title : , Ecotoxycology (2018)
Original Paper

Ecotoxicological Test Assay Using OECD TG 212 in Marine Java Medaka (Oryzias javanicus) and Freshwater Japanese Medaka (Oryzias latipes)

Presenter : Horie Y, Kanazawa N., Yamagishi H., Yonekura K., Tatarazako N
Title : , Bulletin of Environmental Contamination and Toxicology (2018)
Original Paper

The non-steroidal anti-inflammatory drug diclofenac sodium induces abnormal embryogenesis and delayed lethal effects in early-life stage zebrafish (Danio rerio)

Presenter : Horie Y, Yamagishi T., Yagi A., SHINTAKU Y, Iguchi T., Tatarazako N
Title : , Journal of Applied Toxicology (2018)
Original Paper

Synergism between macrolide antibiotics and azole fungicide ketoconazole in green alga Pseudokirchneriella subcapitata

Presenter : Yamagishi T., Horie Y., Tatarazako N.
Title : , Chemosphere, 174:1-7 (2017)
Original Paper

Lethal and sublethal effects of aniline and chlorinated anilines on zebrafish embryos and larvae: Lethal and sublethal effects of chlorinated anilines on zebrafish

Presenter : Horie Y., Yamagishi T., Koshio M., Tatarazako N.
Title : , Journal of applied toxicology (2017)
Original Paper

Cell reproductive patterns in the green alga Pseudokirchneriella subcapitata (Selenastrum capricornutum) and their variations under exposure to the typical toxicants potassium dichromate and 3,5-DCP

Presenter : Yamagishi T., Yamaguchi H., Suzuki S., Horie Y., Tatarazako N.
Title : , PLoS ONE, 12(2):e0171259 (2017)
Original Paper

Effects of triphenyltin on reproduction in Japanese medaka (Oryzias latipes) across two generations

Presenter : Horie Y., Watanabe H., Takanobu H., Yamagishi T., Iguchi T., Tatarazako N.
Title : , Aquatic Toxicology, 192:16-23 (2017)
Original Paper

Complete genome sequence of Cyanobium sp. NIES-981, a marine strain potentially useful for ecotoxicological bioassays

Presenter : Yamaguchi H., Shimura Y., SUZUKI S, Yamagishi T., Tatarazako N., Kawachi M.
Title : , Genome Announcements, 4(4):e00736-16 (2016)
Original Paper

Development of an in vivo anti-androgenic activity detection assay using fenitrothion in Japanese medaka (Oryzias latipes).

Presenter : Horie Y., Watanabe H., Takanobu H, Yagi A., Yamagishi T., Iguchi T, Tatarazako N.
Title : , Journal of Applied Toxicology (2016)
Original Paper

Rapid ecotoxicological bioassay using delayed fluorescence in the marine cyanobacterium Cyanobium sp.(NIES-981)

Presenter : Yamagishi T., Katsumata M, Yamaguchi H., Shimura Y., Kawachi M., Koshikawa H., Horie Y., Tatarazako N.
Title : , Ecotoxicology, 25(10):1751-1758 (2016)
Original Paper

Development of an in vivo anti-androgenic activity detection assay using fenitrothion in Japanese medaka (Oryzias latipes)

Presenter : Horie Y., Takanobu H., Yagi A., Yamagishi T., Taisen Iguchi, Tatarazako N.
Title : , Journal of applied toxicology, 37(3):339-346 (2016)

View all

Ecotoxicity assessment of phthalic acid di-alkyl ester mixtures toward aquatic organisms based on results from a series of subchronic toxicity tests

Presenter : Oda Y., Kawano M., Watanabe H., Yamagishi T., Yamamoto H.
Title : , Environmental Toxicology and Chemistry (2025)
Polyethylene microbead distribution in sediment toxicity test system with estuarine amphipod Grandidierella japonica

Presenter : Hiki K., Namba N,, Watanabe H., Yamagishi T., Yamamoto H.
Title : , Environmental Toxicology and Chemistry, 44(11):3086-3094 (2025)
Prediction of chronic toxicity of pharmaceuticals in Daphnia magna by combining ortholog prediction, pharmacological effects, and quantitative structure-activity relationship

Presenter : Ninomiya Y., Watanabe H., Yamagishi T., Maruyama-Komoda T., Yamada T., Yamamoto H.
Title : , Ecotoxicology and Environmental Safety, 282(116737): (2024)
Development of a microplate-based novel toxicity bioassay using Chlorophyta and Phaeophyceae macroalgae

Presenter : Onduka T., Somiya R., Yamagishi T., Hano T., Yamamoto H., Mochida K.
Title : , Ecotoxicology (2023)
Environmental RNA as a Noninvasive Tool for Assessing Toxic Effects in Fish: A Proof-of-concept Study Using Japanese Medaka Exposed to Pyrene

Presenter : Hiki K., Yamagishi T., Yamamoto H.
Title : , Environmental Science & Technology, 57(34):12654-12662 (2023)
Potential differences in chitin synthesis ability cause different sensitivities to diflubenzuron among three strains of Daphnia magna

Presenter : KATO K., Okamura K., Hiki K., Kintsu H., Nohara K., Yamagishi T., Nakajima N., Watanabe H., Yamamoto H.
Title : , Aquatic Toxicology, 243(106071): (2022)
Severity classification of clinical signs and defining the moribund state as an experimental endpoint for acute toxicity testing using Japanese medaka (Oryzias latipes)

Presenter : Yamagishi T., Kawano M., Watanabe H., Yagi A., Shintaku Y., Ohno K., Yamamoto H.
Title : , Environmental Toxicology and Chemistry, 41(4):1089-1095 (2022)
Propidium iodide staining and flow cytometry-based assessment of heavy metal impact on marine phytoplankton

Presenter : Ota S., Fuchida S., Yamaguchi H., Yamagishi T., Yamamoto H., Koshikawa H., Kawachi M.
Title : , Cytologia, 87(2):177-187 (2022)
Rapid transcriptomic and physiological changes in the freshwater pennate diatom Mayamaea pseudoterrestris in response to copper exposure

Presenter : Suzuki S., Ota S., Yamagishi T., Tuji A., Yamaguchi H., Kawachi M.
Title : , DNA Research, 29(6):1-12 (2022)
Toxicity assessment of typical polycyclic aromatic hydrocarbons to Daphnia magna and Hyalella azteca in water-only and sediment-water exposure systems

Presenter : Tani K., Watanabe H., Noguchi M., Hiki K., Yamagishi T., Yamamoto H.
Title : , Science of the Total Environment, 784(147156): (2021)
Alternative Diatom Strains for Growth Inhibition Tests (OECD Test Guideline 201)

Presenter : Tuji A., Suzuki S., Yamagishi T., Yamaguchi H.
Title : , Bull. Natl. Mus. Nat. Sci., Ser. B, 47(4):1-10 (2021)
Differential heavy metal sensitivity in seven algal species from the NIES culture collection based on delayed fluorescence assays

Presenter : Ota S., Yamaguchi H., Vanel F., Fuchida S., Koshikawa H., Yamagishi T., Yamamoto H., Kawachi M.
Title : , Phycological Research, 68(1):41-49 (2020)
Comparative genome analysis of test algal strain NIVA-CHL1 (Raphidocelis subcapitata) maintained in microalgal culture collections worldwide

Presenter : Yamagishi T., Yamaguchi H., Suzuki S., Yoshikawa M. , Jameson I., Lorenz M., Nobles D.R., Campbell C., Seki M., Kawachi M., Yamamoto H.
Title : , PLOS ONE, 15(11):e0241889 (2020)
Ecotoxicological Test Assay Using OECD TG 212 in Marine Java Medaka (Oryzias javanicus) and Freshwater Japanese Medaka (Oryzias latipes)

Presenter : Horie Y, Kanazawa N., Yamagishi H., Yonekura K., Tatarazako N
Title : , Bulletin of Environmental Contamination and Toxicology (2018)
The non-steroidal anti-inflammatory drug diclofenac sodium induces abnormal embryogenesis and delayed lethal effects in early-life stage zebrafish (Danio rerio)

Presenter : Horie Y, Yamagishi T., Yagi A., SHINTAKU Y, Iguchi T., Tatarazako N
Title : , Journal of Applied Toxicology (2018)
Synergism between macrolide antibiotics and azole fungicide ketoconazole in green alga Pseudokirchneriella subcapitata

Presenter : Yamagishi T., Horie Y., Tatarazako N.
Title : , Chemosphere, 174:1-7 (2017)
Lethal and sublethal effects of aniline and chlorinated anilines on zebrafish embryos and larvae: Lethal and sublethal effects of chlorinated anilines on zebrafish

Presenter : Horie Y., Yamagishi T., Koshio M., Tatarazako N.
Title : , Journal of applied toxicology (2017)
Cell reproductive patterns in the green alga Pseudokirchneriella subcapitata (Selenastrum capricornutum) and their variations under exposure to the typical toxicants potassium dichromate and 3,5-DCP

Presenter : Yamagishi T., Yamaguchi H., Suzuki S., Horie Y., Tatarazako N.
Title : , PLoS ONE, 12(2):e0171259 (2017)
Effects of triphenyltin on reproduction in Japanese medaka (Oryzias latipes) across two generations

Presenter : Horie Y., Watanabe H., Takanobu H., Yamagishi T., Iguchi T., Tatarazako N.
Title : , Aquatic Toxicology, 192:16-23 (2017)
Complete genome sequence of Cyanobium sp. NIES-981, a marine strain potentially useful for ecotoxicological bioassays

Presenter : Yamaguchi H., Shimura Y., SUZUKI S, Yamagishi T., Tatarazako N., Kawachi M.
Title : , Genome Announcements, 4(4):e00736-16 (2016)
Development of an in vivo anti-androgenic activity detection assay using fenitrothion in Japanese medaka (Oryzias latipes).

Presenter : Horie Y., Watanabe H., Takanobu H, Yagi A., Yamagishi T., Iguchi T, Tatarazako N.
Title : , Journal of Applied Toxicology (2016)
Rapid ecotoxicological bioassay using delayed fluorescence in the marine cyanobacterium Cyanobium sp.(NIES-981)

Presenter : Yamagishi T., Katsumata M, Yamaguchi H., Shimura Y., Kawachi M., Koshikawa H., Horie Y., Tatarazako N.
Title : , Ecotoxicology, 25(10):1751-1758 (2016)
Development of an in vivo anti-androgenic activity detection assay using fenitrothion in Japanese medaka (Oryzias latipes)

Presenter : Horie Y., Takanobu H., Yagi A., Yamagishi T., Taisen Iguchi, Tatarazako N.
Title : , Journal of applied toxicology, 37(3):339-346 (2016)

View all

Ecotoxicological Bioassay Using Marine Algae for Deep-Sea Mining

Presenter : Yamagishi T., Ota S., Yamaguchi H., Koshikawa H., Tatarazako, N., Yamamoto H., Kawachi M.
Title : , Environmental Issues of Deep-Sea Mining: Impacts, Consequences and Policy Perspectives (2019)

View all

The complete mitochondrial genome of water flea Ceriodaphnia dubia (Crustacea: Cladocera) NIES strain

Presenter : Hiki K., Oka K., Nakajima N., Watanabe H., Yamamoto H., Yamagishi T.
Title : , Mitochondrial DNA Part B: Resources, 8(8):831-835 (2023)
Acute Toxicity of a Tire Rubber-Derived Chemical, 6PPD Quinone, to Freshwater Fish and Crustacean Species

Presenter : Hiki K., Asahina K., KATO K., Yamagishi T., Omagari R., Iwasaki Y., Watanabe H., Yamamoto H.
Title : , Environmental Science & Technology Letters, 8(9):779-784 (2021)
The complete mitochondrial genome of the non-biting midge Chironomus yoshimatsui (Diptera: Chironomidae)

Presenter : Hiki K., Oka K., Nakajima N., Yamamoto H., Yamagishi T., Sugaya Y.
Title : , Mitochondrial DNA Part B, 6(10):2995-2996 (2021)
Evaluation of the toxicity of leaches from hydrothermal sulfide deposits by means of a delayed fluorescence-based bioassay with the marine cyanobacterium Cyanobium sp. NIES-981

Presenter : Yamagishi T., Fuchida S., Katsumata M, Horie Y, Mori F., Kawachi M., Koshikawa H., Nozaki T., Kumagai H., Ishibasi J., Tatarazako N
Title : , Ecotoxycology (2018)

View all

Research Result (Presentation)

Research Lecture

Environmental risk assessment of chemical mixtures considering their mode of action, structure, and exposure profile

Presenter : Yamamoto H., Watanabe H., Oda Y., Yamagishi T., Hiki K., Imaizumi Y., Yokomizo H., Ozawa F., Ohno K.
Name of Society : The 52nd Annual Meeting of the Japan Society of Toxicology (2025)
Name of Proceedings : The Journalof Toxicological Sciences, 50(Supplement 1):S42
Research Presentation

The Zebrafish Extended One Generation Reproduction Test (ZEOGRT) - Experiences and Current Results from the Validation Exercise

Presenter : Teigeler M., Eilebrecht E., Franzen K., Cahill B., Maunder R.J., Yamagishi T., Watanabe H., Yamamoto H., Holbech H., Schaudien D., Maack G., Walter-Rohde S.
Name of Society : SETAC Europe 35th Annual Meeting (2025)
Name of Proceedings : Abstracts, 200-201
Research Presentation

Ecological Risk Assessment of Human Pharmaceuticals Detected in Japan: Seasonal and Temporal Variations

Presenter : Yamamoto H., Ninomiya Y., Watanabe H., Yamagishi T., Kobayashi N., Yamada T.
Name of Society : SETAC Europe 35th Annual Meeting (2025)
Name of Proceedings : Abstracts, 968
Research Presentation

Analysis of environmental RNA in fish toxicity test with pyrene: a non-invasive approach

Presenter : Hiki K., Yamagishi T., Yamamoto H.
Name of Society : SETAC Asia-Pacific 14th Biennial Meeting (2024)
Name of Proceedings : Abstracts
Research Presentation

Mixture effects of dialkylesters of phthalic acids (PAEs) on aquatic organisms based on predicted environmental exposure profiles

Presenter : Oda Y., Imaizumi Y., Watanabe H., Hiki K., Yamagishi T., Yamamoto H.
Name of Society : 21st International Symposium on Toxicity Assessment (ISTA21) (2024)
Name of Proceedings : -
Research Presentation

How much known chemical substances in receiving water can explain the measured toxicity to alga, daphnid and fish?

Presenter : Watanabe H., Nakajima D., Yamagishi T., Yamamoto H.
Name of Society : 21st International Symposium on Toxicity Assessment (ISTA21) (2024)
Name of Proceedings : Abstracts, 70
Research Presentation

A novel approach for categorizing mode of action of chemicals by utilizing time-to-death observed in the fish acute toxicity test

Presenter : Huang R., Yamagishi T., Hiki K., Ohno K., Watanabe H., Yamamoto H.
Name of Society : 3rd Joint Concerence on Environmental Chemicals (2024)
Name of Proceedings : Abstract
Research Presentation

Classification of clinical signs an defining the moribund state in acute toxicity testing using Zebrafish

Presenter : Aiyi Sui, Yamagishi T., Kobayashi M.
Name of Society : 日本生化学会関東支部例会 (2024)
Name of Proceedings : Abstracts
Research Presentation

Ecological risk assessment of human pharmaceuticals detected in Japan and establishment of ecotoxicity database

Presenter : Yamamoto H., Ninomiya Y., Watanabe H., Yamagishi T., Kobayashi N., Ikarashi Y., Yamada, Hirose A.
Name of Society : SETAC Europe 34th Annual Meeting (2024)
Name of Proceedings : Abstracts
Research Presentation

Toward the Tier Two Environmental Risk Assessment of Groups of Chemicals: A Case Study on Sulfa Drugs

Presenter : Ozawa F., Watanabe H., Yamagishi T., Sato R., Maichi S., Yamamoto H., Ohno K.
Name of Society : SETAC Europe 34th Annual Meeting (2024)
Name of Proceedings : Abstracts
Research Presentation

Assessing the applicability domain of fish embryo toxicity test as alternatives of fish acute toxicity test, utilizing time-to-death in FET test

Presenter : Huang R., Yamagishi T., Watanabe H., Ohno K., Yamamoto H.
Name of Society : SETAC Europe 34th Annual Meeting (2024)
Name of Proceedings : Abstracts
Enhancing Surface Seawater Monitoring during Deep-Sea Mining: Onboard Bioassay and Phyto-Alert Systems

Presenter : Koshikawa H., Ota S., Yamagishi T., Namba N,, Kawachi M.
Name of Society : The 9th Asian Pacific Phycological Forum (APPF 2020) (2024)
Name of Proceedings : The 9th Asian Pacific Phycological Forum (APPF 2020), 142
Research Presentation

Evaluation of the Mode of Action (MoA) of Chemicals Based on Time-to- Death Data Obtained from Fish Embryo Acute Toxicity (FET) Test

Presenter : Huang R., Yamagishi T., Watanabe H., Hiki K., Ohno K., Yamamoto H.
Name of Society : SETAC North America 45th Annual Meeting (2024)
Name of Proceedings : Abstracts, 160
Research Presentation

Identification of causative toxicants in river waters using bioassays with alga and daphnid and multiple-component chemical analysis

Presenter : Watanabe H., Yamagishi T., Omagari R., Nakajima D., Yamamoto H.
Name of Society : SETAC North America 44th Annual Meeting (2023)
Name of Proceedings : Abstracts, 20
Research Presentation

Mixture Effects of Phthalate Esters and Their Subgrouping Based on Toxicity Profiles

Presenter : Yamamoto H., Oda Y., Watanabe H., Yamagishi T., Hiki K., Ozawa F., Ohno K.
Name of Society : SETAC North America 44th Annual Meeting (2023)
Name of Proceedings : Abstracts, 117
Research Presentation

Ecotoxicity characterization of pharmaceuticals in relation to physiological responses of algae for sufficiently conservative environmental risk assessment using in silico tools

Presenter : Ninomya Y., Watanabe H., Yamagishi T., Yamamoto H.
Name of Society : SETAC Asia-Pacific 2022 Virtual Meeting (2022)
Name of Proceedings : -
Research Presentation

Sensitivity Response Changes of Microbe-Associated Daphnia magna under Organophosphate Stress

Presenter : Villegas V., Yamagishi T., Watanabe H., Yamamoto H.
Name of Society : The 56th Annual Conference of Japan Society on Water Environment (2022)
Name of Proceedings : Proceeding of the 56th Annual Conference of Japan Society on Water Environment, 333
Research Presentation

Comparison of headspace and conventional passive dosing techniques to prepare aquatic solution of selected semi-volatile and highly volatile organic chemicals for aquatic toxicity tests with D. magna

Presenter : Lu Y., Yamagishi T., Watanabe H., Yamamoto H.
Name of Society : The 56th Annual Conference of Japan Society on Water Environment 2022 (2022)
Name of Proceedings : Proceeding of the 56th Annual Conference of Japan Society on Water Environment 2022, 332
Research Presentation

Various clinical signs of Japanese medaka (Oryzias latipes) in fish acute toxicity test and their link with moribundity and death

Presenter : Yamagishi T., Watanabe H., Yamamoto H.
Name of Society : SETAC North America 43rd Annual Meeting (2022)
Name of Proceedings : Abstracts, 215
Research Presentation

Recent trend in OECD fish tests for chemical management and the test method development in NIES

Presenter : Yamamoto H., Watanabe H., Yamagishi T.
Name of Society : 第27回小型魚類研究会 (2021)
Name of Proceedings : The 27th Japanese Medaka and Zebrafish Meeting, 39
Research Presentation

Short-term chronic toxicity of acrylic acid and acrylates esters to alga, daphnid and fish

Presenter : Watanabe H., Kawano M., Yamagishi T., Ozawa F., Ohno K., Yamamoto H.
Name of Society : SETAC North America 41st Annual Meeting (2020)
Name of Proceedings : Abstracts, 142
Research Presentation

Case Studies of Toxicity Reduction Evaluation/Toxicity Identification Evaluation on Industrial Effluent in Japan

Presenter : Watanabe H., Yamagishi T., Abe R., Tatarazako N., Yamamoto H.
Name of Society : IWA World Water Congress and Exhibition 2018 (2018)
Name of Proceedings : -
Research Presentation

Onboard ecotoxicological technique to qualify the surface water safety during full-scale mining operation of SMS deposits

Presenter : Koshikawa H., Yamagishi T., Fuchida S., Tatarazako N., Kawachi M.
Name of Society : STAR2017, The Pacific Islands Science, Technology, and Resources Conference (2017)
Name of Proceedings : Abstracts, 23
Research Presentation

Evaluation of metal dissolution from fresh hydrothermal core samples collected at Izena Hole during CK16-05 and rapid detection of their toxicity on marine phytoplankton community; Environmental impact assessment for seafloor metal-mining

Presenter : Fuchida S., Yamagishi T., Koshikawa H., Kawachi M., Fukuhara T., Kumagai H., Nozaki T., Ishibashi J., Maeda L., CK16-05 shipboard scientists
Name of Society : Japan Geoscience Union Meeting 2017 (2017)
Name of Proceedings : Abstract
Research Presentation

DEEP SEA MINING AND ITS POSSIBLE IMPACT ON SURFACE PHYTOPLANKTON AT HYDROTHERMAL FIELDS

Presenter : Koshikawa H., Fuchida S., Yokoyama A., Tsuboi S., Yamagishi T., Kawachi M.
Name of Society : ASLO 2017 Aquatic Sciences Meeting (2017)
Name of Proceedings : -
Research Presentation

Possible impact of seafloor mining on surface microbial diversity at Okinawa Trough

Presenter : Kawachi M., Yamaguchi H., Tsuboi S., Fuchida S., Yamagishi T., Koshikawa H.
Name of Society : ASLO 2017 Aquatic Sciences Meeting (2017)
Name of Proceedings : -
Research Presentation

Development of methods to assess the toxic effects of heavy metals on microalgae using a microbial viability test

Presenter : Ota S., Yamaguchi H., Yamagishi T., Tatarazako N., Fuchida S., Koshikawa H., Kawachi M.
Name of Society : 8th Asian Pacific Phycological Forum (APPF 2017) (2017)
Name of Proceedings : Abstracts, 153
Research Presentation

Possible impacts of seafloor mining on phytoplankton communities at hydrothermal fields

Presenter : Koshikawa H., Fuchida S., Tsuboi S., Yamagishi T., Yokoyama A., Kawachi M.
Name of Society : ACO2016, A connected ocean & EuroGOOS joint workshop program (2016)
Name of Proceedings : -

View all

Mixture effects of dialkylesters of phthalic acids (PAEs) on aquatic organisms based on predicted environmental exposure profiles

Presenter : Oda Y., Imaizumi Y., Watanabe H., Hiki K., Yamagishi T., Yamamoto H.
Name of Society : 21st International Symposium on Toxicity Assessment (ISTA21) (2024)
Name of Proceedings : -
How much known chemical substances in receiving water can explain the measured toxicity to alga, daphnid and fish?

Presenter : Watanabe H., Nakajima D., Yamagishi T., Yamamoto H.
Name of Society : 21st International Symposium on Toxicity Assessment (ISTA21) (2024)
Name of Proceedings : Abstracts, 70
A novel approach for categorizing mode of action of chemicals by utilizing time-to-death observed in the fish acute toxicity test

Presenter : Huang R., Yamagishi T., Hiki K., Ohno K., Watanabe H., Yamamoto H.
Name of Society : 3rd Joint Concerence on Environmental Chemicals (2024)
Name of Proceedings : Abstract
Ecotoxicity characterization of pharmaceuticals in relation to physiological responses of algae for sufficiently conservative environmental risk assessment using in silico tools

Presenter : Ninomya Y., Watanabe H., Yamagishi T., Yamamoto H.
Name of Society : SETAC Asia-Pacific 2022 Virtual Meeting (2022)
Name of Proceedings : -
Sensitivity Response Changes of Microbe-Associated Daphnia magna under Organophosphate Stress

Presenter : Villegas V., Yamagishi T., Watanabe H., Yamamoto H.
Name of Society : The 56th Annual Conference of Japan Society on Water Environment (2022)
Name of Proceedings : Proceeding of the 56th Annual Conference of Japan Society on Water Environment, 333
Comparison of headspace and conventional passive dosing techniques to prepare aquatic solution of selected semi-volatile and highly volatile organic chemicals for aquatic toxicity tests with D. magna

Presenter : Lu Y., Yamagishi T., Watanabe H., Yamamoto H.
Name of Society : The 56th Annual Conference of Japan Society on Water Environment 2022 (2022)
Name of Proceedings : Proceeding of the 56th Annual Conference of Japan Society on Water Environment 2022, 332
Recent trend in OECD fish tests for chemical management and the test method development in NIES

Presenter : Yamamoto H., Watanabe H., Yamagishi T.
Name of Society : 第27回小型魚類研究会 (2021)
Name of Proceedings : The 27th Japanese Medaka and Zebrafish Meeting, 39
Case Studies of Toxicity Reduction Evaluation/Toxicity Identification Evaluation on Industrial Effluent in Japan

Presenter : Watanabe H., Yamagishi T., Abe R., Tatarazako N., Yamamoto H.
Name of Society : IWA World Water Congress and Exhibition 2018 (2018)
Name of Proceedings : -
Onboard ecotoxicological technique to qualify the surface water safety during full-scale mining operation of SMS deposits

Presenter : Koshikawa H., Yamagishi T., Fuchida S., Tatarazako N., Kawachi M.
Name of Society : STAR2017, The Pacific Islands Science, Technology, and Resources Conference (2017)
Name of Proceedings : Abstracts, 23
Evaluation of metal dissolution from fresh hydrothermal core samples collected at Izena Hole during CK16-05 and rapid detection of their toxicity on marine phytoplankton community; Environmental impact assessment for seafloor metal-mining

Presenter : Fuchida S., Yamagishi T., Koshikawa H., Kawachi M., Fukuhara T., Kumagai H., Nozaki T., Ishibashi J., Maeda L., CK16-05 shipboard scientists
Name of Society : Japan Geoscience Union Meeting 2017 (2017)
Name of Proceedings : Abstract
Development of methods to assess the toxic effects of heavy metals on microalgae using a microbial viability test

Presenter : Ota S., Yamaguchi H., Yamagishi T., Tatarazako N., Fuchida S., Koshikawa H., Kawachi M.
Name of Society : 8th Asian Pacific Phycological Forum (APPF 2017) (2017)
Name of Proceedings : Abstracts, 153
The Zebrafish Extended One Generation Reproduction Test (ZEOGRT) - Experiences and Current Results from the Validation Exercise

Presenter : Teigeler M., Eilebrecht E., Franzen K., Cahill B., Maunder R.J., Yamagishi T., Watanabe H., Yamamoto H., Holbech H., Schaudien D., Maack G., Walter-Rohde S.
Name of Society : SETAC Europe 35th Annual Meeting (2025)
Name of Proceedings : Abstracts, 200-201
Ecological Risk Assessment of Human Pharmaceuticals Detected in Japan: Seasonal and Temporal Variations

Presenter : Yamamoto H., Ninomiya Y., Watanabe H., Yamagishi T., Kobayashi N., Yamada T.
Name of Society : SETAC Europe 35th Annual Meeting (2025)
Name of Proceedings : Abstracts, 968
Analysis of environmental RNA in fish toxicity test with pyrene: a non-invasive approach

Presenter : Hiki K., Yamagishi T., Yamamoto H.
Name of Society : SETAC Asia-Pacific 14th Biennial Meeting (2024)
Name of Proceedings : Abstracts
Classification of clinical signs an defining the moribund state in acute toxicity testing using Zebrafish

Presenter : Aiyi Sui, Yamagishi T., Kobayashi M.
Name of Society : 日本生化学会関東支部例会 (2024)
Name of Proceedings : Abstracts
Ecological risk assessment of human pharmaceuticals detected in Japan and establishment of ecotoxicity database

Presenter : Yamamoto H., Ninomiya Y., Watanabe H., Yamagishi T., Kobayashi N., Ikarashi Y., Yamada, Hirose A.
Name of Society : SETAC Europe 34th Annual Meeting (2024)
Name of Proceedings : Abstracts
Toward the Tier Two Environmental Risk Assessment of Groups of Chemicals: A Case Study on Sulfa Drugs

Presenter : Ozawa F., Watanabe H., Yamagishi T., Sato R., Maichi S., Yamamoto H., Ohno K.
Name of Society : SETAC Europe 34th Annual Meeting (2024)
Name of Proceedings : Abstracts
Assessing the applicability domain of fish embryo toxicity test as alternatives of fish acute toxicity test, utilizing time-to-death in FET test

Presenter : Huang R., Yamagishi T., Watanabe H., Ohno K., Yamamoto H.
Name of Society : SETAC Europe 34th Annual Meeting (2024)
Name of Proceedings : Abstracts
Evaluation of the Mode of Action (MoA) of Chemicals Based on Time-to- Death Data Obtained from Fish Embryo Acute Toxicity (FET) Test

Presenter : Huang R., Yamagishi T., Watanabe H., Hiki K., Ohno K., Yamamoto H.
Name of Society : SETAC North America 45th Annual Meeting (2024)
Name of Proceedings : Abstracts, 160
Identification of causative toxicants in river waters using bioassays with alga and daphnid and multiple-component chemical analysis

Presenter : Watanabe H., Yamagishi T., Omagari R., Nakajima D., Yamamoto H.
Name of Society : SETAC North America 44th Annual Meeting (2023)
Name of Proceedings : Abstracts, 20
Mixture Effects of Phthalate Esters and Their Subgrouping Based on Toxicity Profiles

Presenter : Yamamoto H., Oda Y., Watanabe H., Yamagishi T., Hiki K., Ozawa F., Ohno K.
Name of Society : SETAC North America 44th Annual Meeting (2023)
Name of Proceedings : Abstracts, 117
Various clinical signs of Japanese medaka (Oryzias latipes) in fish acute toxicity test and their link with moribundity and death

Presenter : Yamagishi T., Watanabe H., Yamamoto H.
Name of Society : SETAC North America 43rd Annual Meeting (2022)
Name of Proceedings : Abstracts, 215
Short-term chronic toxicity of acrylic acid and acrylates esters to alga, daphnid and fish

Presenter : Watanabe H., Kawano M., Yamagishi T., Ozawa F., Ohno K., Yamamoto H.
Name of Society : SETAC North America 41st Annual Meeting (2020)
Name of Proceedings : Abstracts, 142
DEEP SEA MINING AND ITS POSSIBLE IMPACT ON SURFACE PHYTOPLANKTON AT HYDROTHERMAL FIELDS

Presenter : Koshikawa H., Fuchida S., Yokoyama A., Tsuboi S., Yamagishi T., Kawachi M.
Name of Society : ASLO 2017 Aquatic Sciences Meeting (2017)
Name of Proceedings : -
Possible impact of seafloor mining on surface microbial diversity at Okinawa Trough

Presenter : Kawachi M., Yamaguchi H., Tsuboi S., Fuchida S., Yamagishi T., Koshikawa H.
Name of Society : ASLO 2017 Aquatic Sciences Meeting (2017)
Name of Proceedings : -
Possible impacts of seafloor mining on phytoplankton communities at hydrothermal fields

Presenter : Koshikawa H., Fuchida S., Tsuboi S., Yamagishi T., Yokoyama A., Kawachi M.
Name of Society : ACO2016, A connected ocean & EuroGOOS joint workshop program (2016)
Name of Proceedings : -

View all

Environmental risk assessment of chemical mixtures considering their mode of action, structure, and exposure profile

Presenter : Yamamoto H., Watanabe H., Oda Y., Yamagishi T., Hiki K., Imaizumi Y., Yokomizo H., Ozawa F., Ohno K.
Name of Society : The 52nd Annual Meeting of the Japan Society of Toxicology (2025)
Name of Proceedings : The Journalof Toxicological Sciences, 50(Supplement 1):S42

View all

YAMAGISHI Takahiro

Research Subject

Fiscal Year: 2025

Fiscal Year: 2024

Fiscal Year: 2023

Fiscal Year: 2022

Fiscal Year: 2021

Fiscal Year: 2020

Fiscal Year: 2019

Fiscal Year: 2018

Fiscal Year: 2017

Fiscal Year: 2016

Research Result (Publication)

Research Result (Presentation)