Latest Update：2026/03/24 10:39:51

KAWASHIMA Takaharu

Researcher Name: KAWASHIMA Takaharu

Div (Section) name/title: Health and Environmental Risk Division（Research Office for Environmental Risk Science）／Chief Senior Researcher

Research Subject: Experimental analysis of genetic and environmental factors affecting avian reproduction

Degree(s): Ph.D.

Professional Qualification(s): Bioengineering,Biology,Zootechnical Science

Environmental Speciality Field: environmental technology

Research Subject

Fiscal Year: 2025
- 27215 : Integrative research toward balancing conservation and use of biodiversity and behavior change
- 27248 : Biodiversity Domain: Foresight and Advanced Basic Research
- 27250 : Biodiversity Domain: Intellectual Research Infrastructure Development
- 27510 : Fundamental study for environmental risk assessment
- 27511 : Environmental risk assessment Team
- 27565 : Survey and study on toxicity test methods for high-order predators by persistent and bioaccumulated chemicals in FY2025
Fiscal Year: 2024
- 26828 : Integrative research toward balancing conservation and use of biodiversity and behavior change
- 26866 : Biodiversity Domain: Foresight and Advanced Basic Research
- 26869 : Biodiversity Domain: Intellectual Research Infrastructure Development
- 27107 : Development of an avian in ovo method for evaluating abnormalities in sexual differentiation induced by chemicals and proposal to establish a test guideline
- 27108 : Survey and study on toxicity test methods for high-order predators by persistent and bioaccumulated chemicals in FY2024
- 27134 : Fundamental study for environmental risk assessment
- 27135 : Environmental risk assessment Team
Fiscal Year: 2023
- 26419 : Integrative research toward balancing conservation and use of biodiversity and behavior change
- 26454 : Biodiversity Domain: Foresight and Advanced Basic Research
- 26456 : Biodiversity Domain: Intellectual Research Infrastructure Development
- 26529 : Fundamental study for environmental risk assessment
- 26530 : Environmental risk assessment Team
- 26662 : Development of an avian in ovo method for evaluating abnormalities in sexual differentiation induced by chemicals and proposal to establish a test guideline
- 26663 : Survey and study on toxicity test methods for high-order predators by persistent and bioaccumulated chemicals in FY2023
Fiscal Year: 2022
- 25983 : Integrative research toward balancing conservation and use of biodiversity and behavior change
- 26012 : Biodiversity Domain: Foresight and Advanced Basic Research
- 26014 : Biodiversity Domain: Intellectual Research Infrastructure Development
- 26276 : Fundamental study for environmental risk assessment
- 26277 : Environmental risk assessment Team
- 26286 : Literature survey for setting the registration standard of pesticide to prevent harm to avian species
- 26320 : Development of an avian in ovo method for evaluating abnormalities in sexual differentiation induced by chemicals and proposal to establish a test guideline
- 26321 : Survey and study on toxicity test methods for high-order predators by persistent and bioaccumulated chemicals in FY2022
Fiscal Year: 2021
- 25516 : Integrative research toward balancing conservation and use of biodiversity and behavior change
- 25809 : Biodiversity Domain: Foresight and Advanced Basic Research
- 25811 : Biodiversity Domain: Intellectual Research Infrastructure Development
- 25886 : Fundamental study for environmental risk assessment
- 25888 : Environmental risk assessment Team
- 25962 : Literature survey for setting the registration standard of pesticide to prevent harm to avian species
- 25963 : Study on assessment methods of toxicity to higher predators posed by hardly degradable and highly bioaccumulative chemicals
Fiscal Year: 2020
- 25099 : Research Program on Health and Environmental Safety
- 25141 : Research Project on Health Impacts of Chemicals on Children and Future Generations
- 25196 : Project for the Promotion of Environmental Genomics Studies
- 25426 : Literature survey for setting the registration standard of pesticide to prevent harm to avian species
Fiscal Year: 2019
- 24696 : Research Program on Health and Environmental Safety
- 24721 : Research Project on Health Impacts of Chemicals on Children and Future Generations
- 24858 : Project for the Promotion of Environmental Genomics Studies
- 25031 : Elucidation of the effect and mechanism of neonicotinoid pesticide on development of avian embryo
Fiscal Year: 2018
- 24304 : Research project on health impacts of chemicals on children and future generations
- 24355 : Research program on health and environmental safety
- 24446 : Project for The Promotion of Environmental Genomics studies
- 24564 : Elucidation of the effect and mechanism of neonicotinoid pesticide on development of avian embryo
Fiscal Year: 2017
- 23824 : Research project on health impacts of chemicals on children and future generations
- 23847 : Research program on health and environmental safety
- 23938 : Is sex chromosome-dependent brain sexual differentiation affected by environmental factors?
- 23970 : Project for The Promotion of Environmental Genomics studies
- 24085 : Elucidation of the effect and mechanism of neonicotinoid pesticide on development of avian embryo
Fiscal Year: 2016
- 23414 : Research program on health and environmental safety
- 23415 : Research project on health impacts of chemicals on children and future generations
- 23484 : Project for The Promotion of Environmental Genomics studies
- 23579 : Establishment of multidisciplinary strategy toward comprehensive understanding of developmental neurotoxicity induced by environmental chemicals in house dust
- 23580 : Is sex chromosome-dependent brain sexual differentiation affected by environmental factors?
- 23633 : New analysis of the avian inbreeding depression phenomenon using a technique of chimera production
Fiscal Year: 2015
- 23116 : Establishment of multidisciplinary strategy toward comprehensive understanding of developmental neurotoxicity induced by environmental chemicals in house dust
- 23118 : Is sex chromosome-dependent brain sexual differentiation affected by environmental factors?
- 23260 : New analysis of the avian inbreeding depression phenomenon using a technique of chimera production
Fiscal Year: 2014
- 22802 : Establishment of multidisciplinary strategy toward comprehensive understanding of developmental neurotoxicity induced by environmental chemicals in house dust
- 22874 : New analysis of the avian inbreeding depression phenomenon using a technique of chimera production
Fiscal Year: 2013
- 22307 : Feasibility study for establishment of method to assess developmental neurotoxicity in birds
- 22496 : Establishment of Japanese quail standard inbred strains for toxicity testing of chemicals
Fiscal Year: 2012
- 21966 : Genetic characterization of Japanese quail inbreeding at NIES
Fiscal Year: 2011
- 21492 : Experimental Analysis of Avian Inbreeding Depression during Embryogenesis
Fiscal Year: 2010
- 20912 : Utilization of experimental animals bred for environmental science
- 21130 : Maturation, fertilization and development of avian oocyte.
Fiscal Year: 2009
- 20516 : Utilization of experimental animals bred for environmental science
- 20583 : Maturation and fertilization of avian oocyte in vitro
Fiscal Year: 2008
- 20239 : Evaluation of genetic diversity and cell cryopreservation in endangered birds
- 20276 : Time capsule project for genes and cells of endangered wildlife
- 20277 : Development of new standard environmental assessment using avian culture cells and cryo-banking
Fiscal Year: 2007
- 10375 : Time capsule project for genes and cells of endangered wildlife
- 10422 : Creation of next generation using somatic cells in Aves
- 10447 : Cryo-Phoenix Project in Asia and Eurasia
- 10465 : Development of new standard environmental assessment using avian culture cells and cryo-banking
- 10504 : Experiments for production of interspecific germ-line chimeras in birds
- 10645 : Research and Development on Avian Reproductive Techniques.
- 10692 : Evaluation of genetic diversity and cell cryopreservation in endangered birds
Fiscal Year: 2006
- 10019 : Time capsule project for genes and cells of endangered wildlife
- 10146 : Creation of next generation using somatic cells in Aves
- 10168 : Cryo-Phoenix Project in Asia and Eurasia
- 10186 : Development of new standard environmental assessment using avian culture cells and cryo-banking
- 10196 : Conservation and Use of Avian Bioresource with Developmental Procedures
- 10243 : Experiments for production of interspecific germ-line chimeras in birds
Fiscal Year: 2005
- 9433 : Time capsule project for genes and cells of endangered wildlife
- 9445 : Long-term preservation of genetic bioresources in birds
- 9586 : How many donor cells are sufficient to establish avian germline chimeras?
- 9642 : Creation of next generation using somatic cells in Aves
- 9662 : Cryo-Phoenix Project in Asia and Eurasia
- 9679 : Development of new standard environmental assessment using avian culture cells and cryo-banking
Fiscal Year: 2004
- 9116 : Time capsule project for genes and cells of endangered wildlife
- 9145 : Improvement of artificial reproduction in endangered avian species using embryological techniques
- 9162 : Long-term preservation of genetic bioresources in birds
- 9221 : Production of interspecific germ-line chimeras in birds
Fiscal Year: 2003
- 8830 : Time capsule project for genes and cells of endangered wildlife
- 8848 : A new aspect of artificial reproduction of endangered avian species
- 8882 : Improvement of artificial reproduction in endangered avian species using embryological techniques
- 8897 : Long-term preservation of genetic bioresources in birds

View all

Research Result (Publication)

Original Paper

Ethynylestradiol feminizes gene expression partly in testis developing as ovotestis and disrupts asymmetric Mullerian duct development by eliminating asymmetric gene expression in Japanese quail embryos

Presenter : Abe N., Sakiyama A., Suzuki M., Tin-Tin-Win-Shwe, Suzuki T., Kawashima T., Tsukahara S.
Title : , Toxicological Sciences, 199(2):210-226 (2024)
Original Paper

In ovo o,p'-DDT exposure induces malformation of reproductive organs and alters the expression of genes controlling sexual differentiation in Japanese quail embryo

Presenter : Tin-Tin-Win-Shwe, Abe N., Sakiyama A., Suzuki M., Sano K., Kawashima T., Tsukahara S.
Title : , Journal of Applied Toxicology, 1-13 (2023)
Original Paper

Sexually dimorphic expression of sexual differentiation genes in the internal genital organs of Japanese quail embryos

Presenter : Tsukahara S., Morishita M., Sasaki S., Wakayama K., Kobayashi K., Ohno K., Kawashima T.
Title : , General and Comparative Endocrinology, 314(113917): (2021)
Original Paper

Estrogenic action by tris(2,6-dimethylphenyl) phosphate impairs the development of female reproductive functions

Presenter : Sano K., Matsukami H., Suzuki G., Htike N.T.T., Morishita M., Tin-Tin-Win-Shwe, Hashimoto S., Kawashima T., Isobe T., Nakayama S.F., Tsukahara S., Maekawa F.
Title : , Environment International, 138:105662 (2020)
Original Paper

Strain differences in intermale aggression and possible factors regulating increased aggression in Japanese quail

Presenter : Maekawa F., Nagino K., Yang J., Htike N.T.T., Tsukahara S., Ubuka T., Tsutsui K., Kawashima T.
Title : , General and Comparative Endocrinology, 256:63-70 (2018)
Original Paper

Analyzing the effects of co-expression of chick (Gallus gallus) melanocortin receptors with either chick MRAP1 or MRAP2 in CHO cells on sensitivity to ACTH(1-24) or ACTH(1-13)NH2: Implications for the avian HPA axis and avian melanocortin circuits in the hypothalamus

Presenter : Thomas A.L., Maekawa F., Kawashima T., Sakamoto H., Sakamoto T., Davis P., Dores R.M.
Title : , General and Comparative Endocrinology, 256:50-56 (2018)
Original Paper

Genetic Divergence in Domestic Japanese Quail Inferred from Mitochondrial DNA D-Loop and Microsatellite Markers

Presenter : Nunome M., Nakano M., Tadano R., Kawahara-Miki R., Kono T., Takahashi S., Kawashima T., Fujiwara A., Nirasawa K., Mizutani M., Matsuda Y.
Title : , PLOS ONE, 12(1):1-20 (2017)
Original Paper

In utero and Lactational Exposure to Acetamiprid Induces Abnormalities in Socio-Sexual and Anxiety-Related Behaviors of Male Mice

Presenter : Sano K., Isobe T., Yang J., Tin-Tin-Win-Shwe, Yoshikane M., Nakayama S., Kawashima T., Suzuki G., Hashimoto S., Nohara K., Tohyama C., Maekawa F.
Title : , Frontiers in Neuroscience, 10(228): (2016)
Original Paper

Avian Test Battery for the Evaluation of Developmental Abnormalities of Neuro- and Reproductive Systems

Presenter : Kawashima T., Ahmed W., NAGINO K., Ubuka T., Tsutui K.
Title : , Frontiers in Neuroscience, 10(296): (2016)
Other Publications

A comparative study of sex difference in calbindin neurons among mice, musk shrews, and Japanese quails

Presenter : Moe Y., Tanaka T., Morishita M., Ohta R., Nakahara C., Kawashima T., Maekawa F., Sakata I., Sakai T., Tsukahara S.
Title : , Neuroscience Letters, 631:63-69 (2016)
Review

The mechanisms underlying sexual differentiation of behavior and physiology in mammals and birds: relative contributions of sex steroids and sex chromosomes

Presenter : Maekawa F., Tsukahara S., Kawashima T., Nohara K., Ohki-Hamazaki H.
Title : , Frontiers in Neuroscience, 8(242): (2014)
Original Paper

Next-generation sequencing reveals genomic features in the Japanese quail

Presenter : Kawahara-Miki, Sano, Nunome, Shimmura, Kuwayama, Takahashi S., Kawashima T., Matsuda, Yoshimura, Kono
Title : , Genomics, 101(6):345-353 (2013)
Original Paper

Melatonin receptor genes(mel-1a, mel-1b, mel-1c) are differentially expressed in the avian germ line

Presenter : Kawashima T., Stepińska U., Kuwana T., Olszańska B.
Title : , Mol.Reprod.Dev., 75(9):1408-1417 (2008)

View all

Ethynylestradiol feminizes gene expression partly in testis developing as ovotestis and disrupts asymmetric Mullerian duct development by eliminating asymmetric gene expression in Japanese quail embryos

Presenter : Abe N., Sakiyama A., Suzuki M., Tin-Tin-Win-Shwe, Suzuki T., Kawashima T., Tsukahara S.
Title : , Toxicological Sciences, 199(2):210-226 (2024)
In ovo o,p'-DDT exposure induces malformation of reproductive organs and alters the expression of genes controlling sexual differentiation in Japanese quail embryo

Presenter : Tin-Tin-Win-Shwe, Abe N., Sakiyama A., Suzuki M., Sano K., Kawashima T., Tsukahara S.
Title : , Journal of Applied Toxicology, 1-13 (2023)
Sexually dimorphic expression of sexual differentiation genes in the internal genital organs of Japanese quail embryos

Presenter : Tsukahara S., Morishita M., Sasaki S., Wakayama K., Kobayashi K., Ohno K., Kawashima T.
Title : , General and Comparative Endocrinology, 314(113917): (2021)
Estrogenic action by tris(2,6-dimethylphenyl) phosphate impairs the development of female reproductive functions

Presenter : Sano K., Matsukami H., Suzuki G., Htike N.T.T., Morishita M., Tin-Tin-Win-Shwe, Hashimoto S., Kawashima T., Isobe T., Nakayama S.F., Tsukahara S., Maekawa F.
Title : , Environment International, 138:105662 (2020)
Strain differences in intermale aggression and possible factors regulating increased aggression in Japanese quail

Presenter : Maekawa F., Nagino K., Yang J., Htike N.T.T., Tsukahara S., Ubuka T., Tsutsui K., Kawashima T.
Title : , General and Comparative Endocrinology, 256:63-70 (2018)
Analyzing the effects of co-expression of chick (Gallus gallus) melanocortin receptors with either chick MRAP1 or MRAP2 in CHO cells on sensitivity to ACTH(1-24) or ACTH(1-13)NH2: Implications for the avian HPA axis and avian melanocortin circuits in the hypothalamus

Presenter : Thomas A.L., Maekawa F., Kawashima T., Sakamoto H., Sakamoto T., Davis P., Dores R.M.
Title : , General and Comparative Endocrinology, 256:50-56 (2018)
Genetic Divergence in Domestic Japanese Quail Inferred from Mitochondrial DNA D-Loop and Microsatellite Markers

Presenter : Nunome M., Nakano M., Tadano R., Kawahara-Miki R., Kono T., Takahashi S., Kawashima T., Fujiwara A., Nirasawa K., Mizutani M., Matsuda Y.
Title : , PLOS ONE, 12(1):1-20 (2017)
In utero and Lactational Exposure to Acetamiprid Induces Abnormalities in Socio-Sexual and Anxiety-Related Behaviors of Male Mice

Presenter : Sano K., Isobe T., Yang J., Tin-Tin-Win-Shwe, Yoshikane M., Nakayama S., Kawashima T., Suzuki G., Hashimoto S., Nohara K., Tohyama C., Maekawa F.
Title : , Frontiers in Neuroscience, 10(228): (2016)
Avian Test Battery for the Evaluation of Developmental Abnormalities of Neuro- and Reproductive Systems

Presenter : Kawashima T., Ahmed W., NAGINO K., Ubuka T., Tsutui K.
Title : , Frontiers in Neuroscience, 10(296): (2016)
Next-generation sequencing reveals genomic features in the Japanese quail

Presenter : Kawahara-Miki, Sano, Nunome, Shimmura, Kuwayama, Takahashi S., Kawashima T., Matsuda, Yoshimura, Kono
Title : , Genomics, 101(6):345-353 (2013)
Melatonin receptor genes(mel-1a, mel-1b, mel-1c) are differentially expressed in the avian germ line

Presenter : Kawashima T., Stepińska U., Kuwana T., Olszańska B.
Title : , Mol.Reprod.Dev., 75(9):1408-1417 (2008)

View all

The mechanisms underlying sexual differentiation of behavior and physiology in mammals and birds: relative contributions of sex steroids and sex chromosomes

Presenter : Maekawa F., Tsukahara S., Kawashima T., Nohara K., Ohki-Hamazaki H.
Title : , Frontiers in Neuroscience, 8(242): (2014)

View all

A comparative study of sex difference in calbindin neurons among mice, musk shrews, and Japanese quails

Presenter : Moe Y., Tanaka T., Morishita M., Ohta R., Nakahara C., Kawashima T., Maekawa F., Sakata I., Sakai T., Tsukahara S.
Title : , Neuroscience Letters, 631:63-69 (2016)

View all

Research Result (Presentation)

Research Presentation

Identification of candidate molecular markers for detection of abnormal Müllerian duct morphology in male Japanese quail embryos exposed to estrogenic substances

Presenter : Suzuki T., Sano K., Watanabe K., Tin-Tin-Win-Shwe, Kawashima T.
Name of Society : 59th Congress of the European Societies of Toxicology (EUROTOX 2025) (2025)
Name of Proceedings : Toxicology Letters, 411S:S357
Research Presentation

Utility of multiple shell-less culture system for quail embryos: For the future use in rapid screening assays to predict the developmental toxicity of chemicals

Presenter : Watanabe K., Aoyama H., Sano K., Suzuki T., Tin-Tin-Win-Shwe, Kawashima T.
Name of Society : 59th Congress of the European Societies of Toxicology (EUROTOX 2025) (2025)
Name of Proceedings : Toxicology Letters, 411S:S357
Research Presentation

Development of Avian in Ovo Screening Assay (AIOSA) for Hazard Assessment of Chemicals

Presenter : Tin-Tin-Win-Shwe, Sano K., Suzuki T., Kawashima T.
Name of Society : 1st International Conference: Environmental Pollution and Health Impact on Future Generation in Asian countries (EPHIF2023) (2023)
Name of Proceedings : Abstracts, 67
Research Presentation

Investigation of gene expressions related to aggression in quail diencephalon

Presenter : Maekawa F., Nagino K., Yang J., Htike N.T.T., Tsukahara S., Ubuka T., Tsutsui K., Kawashima T.
Name of Society : The 95th Annual Meeting of the Physiological Society of Japan (2018)
Name of Proceedings : Proceedings of the 95th Annual Meeting of the Physiological Society of Japan, S151
Research Presentation

Developmental exposure to tetrabromobisphenol A (TBBPA) on late onset behavior and neurological biomarkers in adult mice

Presenter : Tin-Tin-Win-Shwe, Sano K., Isobe T., Kawashima T., Suzuki G., Hashimoto S., Nakayama S., Maekawa F.
Name of Society : The 40th Annual Meeting of the Japan Neuroscience Society (2017)
Name of Proceedings : Abstract, 218
Research Presentation

Effects of perinatal exposure to a phosphate ester flame retardant on novel object recognition ability and memory function-related gene expression in adult mice

Presenter : Tin-Tin-Win-Shwe, Sano K., Isobe T., Kawashima T., Suzuki G., Hashimoto S., Nakayama S., Maekawa F.
Name of Society : 45th Myanmar Health Research Congress (2017)
Name of Proceedings : Abstract, 120
Research Presentation

Comprehensive analysis of house dust using GC×GC-HRTOFMS and in-house software

Presenter : Ieda T., Hashimoto S., Takazawa Y., Tanabe K., Zushi Y., Shibata Y., Maekawa F., Sano K., Suzuki G., Nakayama S., Isobe T., Tin-Tin-Win-Shwe, Kawashima T.
Name of Society : DIOXIN2016 (2016)
Name of Proceedings : Abstracts
Research Presentation

Perinatal exposure to a phosphate ester flame retardant affects memory function and related gene expression in adult mice

Presenter : Tin-Tin-Win-Shwe, Sano K., Isobe T., Kawashima T., Suzuki G., Hashimoto S., Nakayama S., Maekawa F.
Name of Society : The 5th Annual Meeting of The Japan Society for Developmental Origins of Health and Disease (DOHaD-Japan) (2016)
Name of Proceedings : Abstract(P-07), 40
Research Presentation

Evaluation of potentially developmentally neurotoxic chemicals using behavioral testing and neuroendocrinological analysis

Presenter : Maekawa F., Sano K., Suzuki G., Nakayama S., Isobe T., Tin-Tin-Win-Shwe, Hashimoto S., Kawashima T.
Name of Society : The 93rd Annual Meeting of the Physiological Society of Japan (2016)
Name of Proceedings : Proceedings of The 93rd Annual Meeting of the Physiological Society of Japan, 66(supplement1):S73
Research Presentation

Male aggressive and reproductive behaviors in long-term breeding closed colony NIES-L of Japanese quail

Presenter : NAGINO K., Ubuka T., Tsutsui K., Maekawa F., Kawashima T.
Name of Society : Avian Model Systems 9: A New Integrative Platform (2016)
Name of Proceedings : Proceedings of Avian Model System 9: A New Integrative Platform, 115
Research Lecture

In vivo evaluation of a flame retardant having estrogenic activity using mouse model

Presenter : Sano K., Suzuki G., Htike N.T.T., Morishita M., Tin-Tin-Win-Shwe, Hashimoto S., Kawashima T., Isobe T., Nakayama S., Tsukahara S., Maekawa F.
Name of Society : Application of Recent Advances in Neuroscience to Environmental Health Research (2016)
Name of Proceedings : abstract, 1-4
Research Presentation

Melanocortin Receptors and MRAP expression in the chick adrenal gland: correlating mRNA expression levels and ligand sensitivity of chick melanocortin receptors expressed in CHO cell

Presenter : Dores R.M., Thomas A., Maekawa F., Kawashima T., Sakamoto H., Sukamoto T.
Name of Society : 11th International Symposium on Avian Endocrinology (2016)
Name of Proceedings : 11th International Symposium on Avian Endocrinology Abstracts, 60
Research Presentation

Analysis of aggressive behavior in two Japanese quail strains and their gene expressions possibly related to aggression in the hypothalamus

Presenter : Maekawa F., Nagino K., Yang J., Ubuka T., Tsutsui K., Kawashima T.
Name of Society : 11th International Symposium on Avian Endocrinology (2016)
Name of Proceedings : 11th International Symposium on Avian Endocrinology Abstracts, 68
Research Lecture

Utility of the Long-Term Closed Colony of Japanese Quails Breeding as Laboratory Animals

Presenter : Kawashima T.
Name of Society : Fifth International Symposium and Fourth Brazilian Congress on Quail Production (2013)
Name of Proceedings : Abstracts, 113-121
Research Presentation

Genetic analyses of long-term breeding closed colony of Japanese quail at NIES using microsatellite markers

Presenter : Kawashima T., Takahashi S.
Name of Society : 7th International Chick Meeting (2012)
Name of Proceedings : Chick7: Avian Model Systems, 110

View all

Evaluation of potentially developmentally neurotoxic chemicals using behavioral testing and neuroendocrinological analysis

Presenter : Maekawa F., Sano K., Suzuki G., Nakayama S., Isobe T., Tin-Tin-Win-Shwe, Hashimoto S., Kawashima T.
Name of Society : The 93rd Annual Meeting of the Physiological Society of Japan (2016)
Name of Proceedings : Proceedings of The 93rd Annual Meeting of the Physiological Society of Japan, 66(supplement1):S73
Identification of candidate molecular markers for detection of abnormal Müllerian duct morphology in male Japanese quail embryos exposed to estrogenic substances

Presenter : Suzuki T., Sano K., Watanabe K., Tin-Tin-Win-Shwe, Kawashima T.
Name of Society : 59th Congress of the European Societies of Toxicology (EUROTOX 2025) (2025)
Name of Proceedings : Toxicology Letters, 411S:S357
Utility of multiple shell-less culture system for quail embryos: For the future use in rapid screening assays to predict the developmental toxicity of chemicals

Presenter : Watanabe K., Aoyama H., Sano K., Suzuki T., Tin-Tin-Win-Shwe, Kawashima T.
Name of Society : 59th Congress of the European Societies of Toxicology (EUROTOX 2025) (2025)
Name of Proceedings : Toxicology Letters, 411S:S357
Development of Avian in Ovo Screening Assay (AIOSA) for Hazard Assessment of Chemicals

Presenter : Tin-Tin-Win-Shwe, Sano K., Suzuki T., Kawashima T.
Name of Society : 1st International Conference: Environmental Pollution and Health Impact on Future Generation in Asian countries (EPHIF2023) (2023)
Name of Proceedings : Abstracts, 67
Investigation of gene expressions related to aggression in quail diencephalon

Presenter : Maekawa F., Nagino K., Yang J., Htike N.T.T., Tsukahara S., Ubuka T., Tsutsui K., Kawashima T.
Name of Society : The 95th Annual Meeting of the Physiological Society of Japan (2018)
Name of Proceedings : Proceedings of the 95th Annual Meeting of the Physiological Society of Japan, S151
Developmental exposure to tetrabromobisphenol A (TBBPA) on late onset behavior and neurological biomarkers in adult mice

Presenter : Tin-Tin-Win-Shwe, Sano K., Isobe T., Kawashima T., Suzuki G., Hashimoto S., Nakayama S., Maekawa F.
Name of Society : The 40th Annual Meeting of the Japan Neuroscience Society (2017)
Name of Proceedings : Abstract, 218
Effects of perinatal exposure to a phosphate ester flame retardant on novel object recognition ability and memory function-related gene expression in adult mice

Presenter : Tin-Tin-Win-Shwe, Sano K., Isobe T., Kawashima T., Suzuki G., Hashimoto S., Nakayama S., Maekawa F.
Name of Society : 45th Myanmar Health Research Congress (2017)
Name of Proceedings : Abstract, 120
Comprehensive analysis of house dust using GC×GC-HRTOFMS and in-house software

Presenter : Ieda T., Hashimoto S., Takazawa Y., Tanabe K., Zushi Y., Shibata Y., Maekawa F., Sano K., Suzuki G., Nakayama S., Isobe T., Tin-Tin-Win-Shwe, Kawashima T.
Name of Society : DIOXIN2016 (2016)
Name of Proceedings : Abstracts
Perinatal exposure to a phosphate ester flame retardant affects memory function and related gene expression in adult mice

Presenter : Tin-Tin-Win-Shwe, Sano K., Isobe T., Kawashima T., Suzuki G., Hashimoto S., Nakayama S., Maekawa F.
Name of Society : The 5th Annual Meeting of The Japan Society for Developmental Origins of Health and Disease (DOHaD-Japan) (2016)
Name of Proceedings : Abstract(P-07), 40
Male aggressive and reproductive behaviors in long-term breeding closed colony NIES-L of Japanese quail

Presenter : NAGINO K., Ubuka T., Tsutsui K., Maekawa F., Kawashima T.
Name of Society : Avian Model Systems 9: A New Integrative Platform (2016)
Name of Proceedings : Proceedings of Avian Model System 9: A New Integrative Platform, 115
Melanocortin Receptors and MRAP expression in the chick adrenal gland: correlating mRNA expression levels and ligand sensitivity of chick melanocortin receptors expressed in CHO cell

Presenter : Dores R.M., Thomas A., Maekawa F., Kawashima T., Sakamoto H., Sukamoto T.
Name of Society : 11th International Symposium on Avian Endocrinology (2016)
Name of Proceedings : 11th International Symposium on Avian Endocrinology Abstracts, 60
Analysis of aggressive behavior in two Japanese quail strains and their gene expressions possibly related to aggression in the hypothalamus

Presenter : Maekawa F., Nagino K., Yang J., Ubuka T., Tsutsui K., Kawashima T.
Name of Society : 11th International Symposium on Avian Endocrinology (2016)
Name of Proceedings : 11th International Symposium on Avian Endocrinology Abstracts, 68
Genetic analyses of long-term breeding closed colony of Japanese quail at NIES using microsatellite markers

Presenter : Kawashima T., Takahashi S.
Name of Society : 7th International Chick Meeting (2012)
Name of Proceedings : Chick7: Avian Model Systems, 110

View all

Utility of the Long-Term Closed Colony of Japanese Quails Breeding as Laboratory Animals

Presenter : Kawashima T.
Name of Society : Fifth International Symposium and Fourth Brazilian Congress on Quail Production (2013)
Name of Proceedings : Abstracts, 113-121
In vivo evaluation of a flame retardant having estrogenic activity using mouse model

Presenter : Sano K., Suzuki G., Htike N.T.T., Morishita M., Tin-Tin-Win-Shwe, Hashimoto S., Kawashima T., Isobe T., Nakayama S., Tsukahara S., Maekawa F.
Name of Society : Application of Recent Advances in Neuroscience to Environmental Health Research (2016)
Name of Proceedings : abstract, 1-4

View all

KAWASHIMA Takaharu

Research Subject

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Research Result (Publication)

Research Result (Presentation)