Nitroaromatics and derivatives

Nitroaromatic compounds and their numerous derivatives are of use as explosives and propellants both in the military and industory. A number of studies have shown that nitro compounds, their metabolites of environmental transformation and by-products of their synthesis or incomplete combustion are harmful for the biosphere due to their toxicity. For instance, toxic effects in humans after dermal, oral or respiratory exposure include gastrointestinal, neurological and reproductive disorders, cirrhosis of the liver, hepatitis, cataracts, respiratory and skin irritation, nephrotoxicity, and hematological defects. More over, nitroaromatic compounds are widey used in medicine, industry and agriculture. (ref. ID; 7772)

[2-Amino-4-chloro-5-nitrophenol]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

[2-Amino-6-chloro-4-nitrophenol] CAS[6358-09-4]
Chemical formula; C6H5ClN2O3
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[4-Amino-3,5-dinitrobenzamide]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[2-Amino-4,6-dinitrotoluene] (2-ADNT) CAS[35572-78-2]
Chemical characteristics; 2,4,6-Trinitrotoluene (TNT) metabolites.
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[3-Amino-2,6-dinitrotoluene]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[2-Amino-4-nitrophenol] CAS[99-57-0]
Chemical formula; H2NC6H3(NO2)OH
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

[4-Amino-2-nitrophenol]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

[ANTA (3-Nitro-1,2,4-triazol-5-amine)]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[2-Bromo-4,6-dinitroaniline] CAS[1817-73-8]
Chemical formula; C6H4BrN3O4
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[6-Bromo-1,3-dinitrobenzene]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

[4-Bromo-2-fluoro-6-nitrophenol]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[2-Bromo-2'-hydroxy-5'-nitroacetanilide]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)


[Bromonitrobenzene]

2-Bromonitrobenzene CAS[577-19-5] UN2732
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

3-Bromonitrobenzene CAS[585-79-5] UN2732
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

4-Bromonitrobenzene CAS[586-78-7] UN2732
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)


[4-Butoxynitrobenzene]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

[4-(tert)Butyl-2,6-dinitrophenol] CAS[4097-49-8]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[4-Chloro-2,6-dinitroaniline]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[6-Chloro-2,4-dinitroaniline] CAS[3531-19-9] UN2237
Chemical formula; ClC6H3(NO2)2NH2
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[1-Chloro-2,4-dinitrobenzene] (CDNB) CAS[97-00-7]
= 2,4-Dinitrochlorobenzene
Chemical formula; C6H3ClN2O4
Test organisms;
Protozoa: Spirostomum ambiguum (ref. ID; 6983)
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
Rotifera: Brachionus calyciflorus (ref. ID; 127)

[4-Chloro-3,5-dinitrobenzonitrile]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[5-Chloro-2,4-dinitrotoluene]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[3-Chloro-4-fluoronitrobenzene]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[2-Chloromethyl-4-nitrophenol]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

[2-Chloro-5-nitroaniline] CAS[6283-25-6] UN2237
Chemical formula; ClC6H3(NO2)NH2
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[2-Chloro-6-nitroaniline]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[2-Chloro-5-nitrobenzaldehyde] CAS[6361-21-3]
Chemical formula; ClC6H3(NO2)CHO
Chemical characteristics; Log Ko/w 2.25. (ref. ID; 7771)
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7771, 7772)

[2-Chloro-6-nitrobenzaldehyde]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[4-Chloro-6-nitrobenzaldehyde]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[5-Chloro-2-nitrobenzamide]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)


[Chloronitrobenzene]
Chemical formula; ClC6H4NO2

2-Chloronitrobenzene CAS[88-73-3] UN1578
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

3-Chloronitrobenzene
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

4-Chloronitrobenzene CAS[100-00-5] UN1578
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)


[4-Chloro-3-nitrobenzonitrile] CAS[939-80-0]
Chemical formula; C7H3ClN2O2
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[4-Chloro-6-nitromcresol]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

[2-Chloro-4-nitrophenol] CAS[619-08-9] UN1759
Chemical formula; ClC6H3(NO2)OH
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

[4-Chloro-2-nitrophenol] CAS[89-64-5] UN2811
Chemical formula; ClC6H3(NO2)OH
Chemical characteristics; Logarithm of 1-octanol/water partition coefficient log Kow 2.46. (ref. ID; 6981)
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

[4-Chloro-3-nitrophenol] CAS[610-78-6]
Chemical formula; C6H4ClNO3
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[2,4-Chloro-6-nitrophenol]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

[2-Chloro-6-nitrotoluene] CAS[83-42-1] UN43457
Chemical formula; CH3C6H3(NO2)Cl
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[4-Chloro-2-nitrotoluene] CAS[89-59-8] UN3457
Chemical formula; ClC6H3(NO2)CH3
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[CL-14]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[CL-20]
2,4,6,8,10,12-Hexanitro-2,4,6,8,10,12-hexazaisowurtzitane CAS[135285-90-4]
= Nitramine
Trade name; CL-20
Purpose for use; Energetic compound (polycyclic nitramine explosive).
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
Oligochaeta: Eisenia andrei (ref. ID; 4572)

[Diaminoazofurazan]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[2,4-Dibromo-6-nitroaniline]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[2,5-Dibromonitrobenzene] CAS[3460-18-2]
Chemical formula; C6H3Br2NO2
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

[2,6-Dibromo-4-nitrophenol] CAS[99-28-5]
Chemical formula; C6H3Br2NO3
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

[2,4-Dichloro-6-nitroaniline] CAS[2683-43-4]
Chemical formula; C6H4Cl2N2O2
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[4,5-Dichloro-2-nitroaniline]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[1,3-Dichloro-4,6-dinitrobenzene] CAS[3698-83-7]
Mode of toxic action; Electro(necleo)phile (ref. ID; 3327)
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 3327, 7772)

[4,6-Dichloro-1,2-dinitrobenzene]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)


[Dichloronitrobenzene]

2,3-Dichloronitrobenzene CAS[3209-22-1] UN1578
Chemical formula; C6H3Cl2NO2
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

2,4-Dichloronitrobenzene CAS[611-06-3] UN1578
Chemical formula; C6H3Cl2NO2
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

2,5-Dichloronitrobenzene CAS[89-61-2] UN1578
Chemical formula; C6H3Cl2NO2
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

3,4-Dichloronitrobenzene CAS[99-54-7]
= 1,2-Dichloro-4-nitrobenzene
Chemical formula; C6H3Cl2NO2
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

3,5-Dichloronitrobenzene CAS[618-62-2] UN1578
Chemical formula; C6H3Cl2NO2
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)


[2,6-Dichloro-4-nitrophenol] CAS[618-80-4]
Chemical formula; Cl2C6H2(NO2)OH
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[1,5-Difluoro-2,4-nitroaniline]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[2,5-Difluoronitrobenzene]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[4,5-Difluoro-2-dinitrobenzene]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[2,6-Diiodo-4-nitrophenol] CAS[305-85-1]
Chemical formula; C6H3I2NO3
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

[1,2-Dimethyl-4-nitrobenzene]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[1,3-Dimethyl-2-nitrobenzene] CAS[81-20-9] UN1665
Chemical formula; (CH3)2C6H3NO2
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

[2,3-Dimethylnitrobenzene]
= 1,2-Dimethyl-3-nitrobenzene CAS[83-41-0] UN1665
Chemical formula; (CH3)2C6H3NO2
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

[Dimethylnitroterephthalate]
= Dimethyl Nitroterephthalate CAS[5292-45-5]
Chemical fromula; C10H9NO6
Mode of toxic action; Diester (ref. ID; 3327)
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 3327, 7772)


[Dinitroaniline]
Chemical formula; (O2N)2C6H3NH2

2,4-Dinitroaniline CAS[97-02-9] UN1596
Test organisms;
Protozoa: Spirostomum ambiguum (ref. ID; 6983)
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
Protozoa: Tetrahymena thermophila (ref. ID; 6010)

2,6-Dinitroaniline
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

3,5-Dinitroaniline CAS[618-87-1] UN1596
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)


[Dinitrobenzene]
Chemical formula; C6H4(NO2)2

1,2-Dinitrobenzene CAS[528-29-0] UN3443
Chemical characteristics; log Kow 1.67. (ref. ID; 449)
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 449, 6709, 7772)

1,3-Dinitrobenzene CAS[99-65-0] UN3443
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

1,4-Dinitrobenzene CAS[100-25-4] UN3443
Chemical characteristics; log Kow 1.60. (ref. ID; 449)
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 449, 6709, 7772)


[3,5-Dinitrobenzonitrile] CAS[4110-35-4]
Chemical formula; C7H3N3O4
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[3,4-Dinitrobenzyl alcohol]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[3,5-Dinitrobenzyl alcohol] CAS[71022-43-0]
Chemical fromula; C7H6N2O5
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[2,6-Dinitro-4-cresol]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

[3,5-Dinitro-p-cresol]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[4,6-Dinitro-2-cresol] CAS[534-52-1] UN1598
= DNOC
Chemical formula; C7H6N2O5
Purpose for use; Pesticide.
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 3554, 6709, 7772)

[1,2-Dinitro-4,5-dichlorobenzene]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

[2,4-Dinitro-5-fluoroaniline]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[2,4-Dinitro-1-fluorobenzene]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[Dinitroglycouril]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[2,4-Dinitroimidazole]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)


[Dinitrophenol]
Chemical formula; (O2N)2C6H3OH

2,3-Dinitrophenol
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

2,4-Dinitrophenol CAS[51-28-5] UN1320
Chemical characteristics; Lipophilicity log P 1.53. (ref. ID; 6959)
Purpose for use; Fungicide.
Toxicity; 2,4-Dinitrophenol uncouples oxidative phosphorylation without blocking oxygen consumption by dissipating the electrochemical gradient across the inner mitochondrial membrane. In early studies on Tetrahymena, DNP was reported to affect dose-depended respiration, phosphate accumulation, endocytosis, fine structure after a 1-h exposure, and final cell density a 96-h exposure. Effects were enhanced when DNP was tested at acid pH pointing towards the undissociated DNP molecule being active state. (ref. ID; 7348)
Test organisms;
Green algae (formerly including protozoa): Chlamydomonas reinhardtii (ref. ID; 4556)
Protozoa: Spirostomum ambiguum (ref. ID; 6984)
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7348, 7772)
Oligochaeta: Eisenia fetida (ref. ID; 6959)

2,5-Dinitrophenol CAS[329-71-5] UN1320
Test organisms;
Protozoa: Spirostomum ambiguum (ref. ID; 6984)
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

2,6-Dinitrophenol CAS[573-56-8]
Test organisms;
Protozoa: Spirostomum ambiguum (ref. ID; 6984)
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

3,4-Dinitrophenol
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)


[Dinitrosobenzene]

1,3-Dinitrosobenzene
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

1,4-Dinitrosobenzene
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)


[1,3-Dinitro-5-nitroso-1,3,5-triazine]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[1,3-Dinitroso-5-nitro-1,3,5-triazine]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)


[Dinitrotoluene]

2,3-Dinitrotoluene
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

2,5-Dinitrotoluene
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)


[EGDN]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[4-Ethoxy-2-nitroaniline]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[4-Ethylnitrobenzene] CAS[100-12-9]
Chemical formula; C8H9NO2
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

[Ethyl-4-nitrobenzoate]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[1-Fluoro-3-iodo-5-nitrobenzene]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[4-Fluoronitrobenzene] CAS[350-46-9] UN2811
Chemical formula; FC6H4NO2
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

[1-Fluoro-2-nitrobenzene]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[1-Fluoro-3-nitrobenzene]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[3-Fluoro-4-nitrophenol] CAS[394-41-2]
Chemical formula; C6H4FNO3
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[5-Fluoro-2-nitrophenol] CAS[446-36-6]
Chemical formula; C6H4FNO3
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

[FOX-7]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[HBT]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[HMX]
Octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (HMX) CAS[2691-41-0]
= 1,3,5,7-Tetranitro-1,3,5,7-tetrazacyclo-octane (ref. ID; 6865)
Purpose for use; High melting explosive. Toxicity; This explosive is toxic to some aquatic organisms, including fathead minnows (Pimephales promelas) and the freshwater microcrustacean Daphnia magna, and some terrestrial organisms including mice and rats. But, HMX is not toxic to the bioluminescent bacteria Vibrio fisheri and is not cytotoxic or mutagenic to bacterial and mammalian cells in aqueous solutions of HMX. (ref. ID; 6115)
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
Oligochaeta: Eisenia andrei (ref. ID; 4958, 6115, 6817)
Oligochaeta: Lumbricus terrestris (ref. ID; 4958)

[1-Hydroxylamino-3,5-dinitro-1,3,5-triazine]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[1-Hydroxylamino-3,5-dinitroso-1,3,5-triazine]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[2-Hydroxylamino-4,6-dinitrotoluene]
Chemical characteristics; 2,4,6-Trinitrotoluene (TNT) metabolites
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[4-Hydroxylamino-2,6-dinitrotoluene]
Chemical characteristics; 2,4,6-Trinitrotoluene (TNT) metabolites
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[1-Hydroxylamino-3-nitroso-5-nitro-1,3,5-triazine]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[3-Hydroxy-4-nitrobenzaldehyde]
Chemical characteristics; Log Ko/w 1.47. (ref. ID; 7771)
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7771, 7772)

[4-Hydroxy-3-nitrobenzaldehyde] CAS[3011-34-5]
Chemical formula; C7H5NO4
Chemical characteristics; Log Ko/w 1.48. (ref. ID; 7771)
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7771, 7772)

[5-Hydroxy-2-nitrobenzaldehyde] CAS[42454-06-8]
Chemical formula; C7H5NO4
Chemical characteristics; Log Ko/w 1.75. (ref. ID; 7771)
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7771, 7772)

[6-Iodo-1,3-dinitrobenzene]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

[K-55]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[3-Methyl-4-bromonitrobenzene]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

[Methyl-4-chloro-2-nitrobenzoate] CAS[42087-80-9]
Mode of toxic action; Electro(necleo)phile (ref. ID; 3327)
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 3327, 7772)

[5-Methyl-1,2-dinitrobenzene]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

[6-Methyl-1,3-dinitrobenzene]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

[3-Methyl-2,4-dinitrophenol]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[3-Methyl-4,6-dinitrophenol]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[2-Methyl-4-nitroaniline] CAS[99-52-5] UN2660
Chemical formula; CH3C6H3(NO2)NH2
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[4-Methyl-2-nitroaniline] CAS[89-62-3]
Chemical formula; CH3C6H3(NO2)NH2
Chemical characteristics; log Kow 1.82. (ref. ID; 449)
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 449, 7772)

[Methyl-4-nitrobenzoate]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[2-Methyl-3-nitrophenol]
= 3-Nitro-o-cresol CAS[119-33-5] UN2446
Chemical formula; CH3C6H3(NO2)OH
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[2-Methyl-5-nitrophenol] CAS[5428-54-6] UN2446
Chemical formula; C7H7NO3
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[3-Methyl-2-nitrophenol] CAS[4920-77-8]
Chemical formula; C7H7NO3
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[3-Methyl-4-nitrophenol] CAS[2581-34-2] UN2446
Chemical formula; C7H7NO3
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

[4-Methyl-2-nitrophenol]
= 2-Nitro-p-cresol CAS[119-33-5] UN2446
Chemical formula; CH3C6H3(NO2)OH
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

[4-Methyl-3-nitrophenol] CAS[2042-14-0] UN2446
Chemical formula; C7H7NO3
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

[5-Methyl-2-nitrophenol] CAS[700-38-9] UN2446
Chemical formula; C7H7NO3
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[3-Nitroacetophenone]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)


[Nitroaniline]

2-Nitroaniline
Chemical characteristics; log Kow 1.65. (ref. ID; 449)
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 449, 6709, 7772)

3-Nitroaniline
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)


[Nitrobenzaldehyde]
Chemical formula; O2NC6H4CHO

2-Nitrobenzaldehyde CAS[552-89-6]
Chemical characteristics; Log Ko/w 1.74. (ref. ID; 7771)
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7771, 7772)

3-Nitrobenzaldehyde CAS[99-61-6]
Chemical characteristics; Log Ko/w 1.47. (ref. ID; 7771)
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7771, 7772)

4-Nitrobenzaldehyde CAS[555-16-8]
Chemical characteristics; Log Ko/w 1.56. (ref. ID; 7771)
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7771, 7772)


[Nitrobenzamide]
Chemical formula; C7H6N2O3

2-Nitrobenzamide CAS[610-15-1]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

3-Nitrobenzamide CAS[645-09-0]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

4-Nitrobenzamide CAS[619-80-7]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)


[Nitrobenzene] CAS[98-95-3] UN1662
Chemical formula; C6H5NO2
Chemical characteristics; Lipophilicity log P 1.85. (ref. ID; 6959)
Purpose for use; Organic solvents.
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)
Oligochaeta: Allolobophora tuberculata (ref. ID; 7159, 7163)
Oligochaeta: Eisenia fetida (ref. ID: 6959, 7159, 7163)
Oligochaeta: Eudrilus eugeniae (ref. ID; 7159, 7163)
Oligochaeta: Perionyx excavatus (ref. ID; 7159, 7163)
[Nitrobenzoic acid]
= Nitrobenzenecarboxylic acid
Chemical formula; C7H5NO4

2-Nitrobenzoic acid
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

3-Nitrobenzoic acid
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

4-Nitrobenzoic acid
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)


[Nitrobenzonitrile]

2-Nitrobenzonitrile CAS[612-24-8] UN3439
Chemical formula; C7H4N2O2
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

3-Nitrobenzonitrile CAS[619-24-9] UN3439
Chemical formula; O2NC6H4CN
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

4-Nitrobenzonitrile CAS[619-72-7] UN3439
Chemical formula; C7H4N2O2
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)


[Nitrobenzyl alcohol]
Chemical formula; C7H7NO3

2-Nitrobenzyl alcohol
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

3-Nitrobenzyl alcohol
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

4-Nitrobenzyl alcohol
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)


4-Nitrobenzyl chloride
Chemical fromula; H6ClNO2
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[Nitrobiphenyl]
Chemical formula; C12H9NO2

2-Nitrobiphenyl CAS[86-00-0]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

3-Nitrobiphenyl
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)


[4-Nitro-catechol]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[4-Nitrodiphenylamine] CAS[836-30-6]
= N-phenyl-4-nitroaniline
Chemical fromula; C12H10N2O2
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[Nitroglycerin] CAS[55-63-0]
= Glycerol trinitrate
Chemical formula; C3H5N3O9
Purpose for use; Blasting explosive.
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[3-Nitro-2-hydroxybenzaldehyde]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[2-Nitroimino-5-nitro-hexahydro-1,3,5-triazine]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[4-Nitrophenetole]
Chemical formula; C8H9NO3
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)


[Nitrophenol]
Chemical formula; O2NC6H4OH

2-Nitrophenol CAS[88-75-5] UN1663
Trade name; o-nitrophenol (J)
Chemical characteristics; Lipophilicity log P 1.76. (ref. ID; 6959)
Logarithm of 1-octanol/water partition coefficient log Kow 1.79. (ref. ID; 6981)
Purpose for use; Plant growth regulator. pH indicator.
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)
Oligochaeta: Eisenia fetida (ref. ID; 6959, 7163)

3-Nitrophenol CAS[554-84-7] UN1663
Chemical characteristics; Logarithm of 1-octanol/water partition coefficient log Kow 2.00. (ref. ID; 6981)
Purpose for use; pH indicator.
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

4-Nitrophenol CAS[100-02-7] UN1663
Trade name; p-nitrophenol (J)
Chemical characteristics; Lipophilicity log P 1.91. (ref. ID; 6959)
Logarithm of 1-octanol/water partition coefficient log Kow 1.91. (ref. ID; 6981)
Purpose for use; Plant growth regulator. pH indicator.
Pesticide derivatives. (ref. ID; 7012)
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)
Rotifera: Brachionus rubens (ref. ID; 818)
Oligochaeta: Allolobophora tuberculata (ref. ID; 7159, 7163)
Oligochaeta: Eisenia fetida (ref. ID; 6959, 7012, 7159, 7163)
Oligochaeta: Eudrilus eugeniae (ref. ID; 7159, 7163)
Oligochaeta: Perionyx excavatus (ref. ID; 7159, 7163)


[4-Nitrophenylacetonitrile]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[4-Nitrophenyl-phenyl-ether] CAS[620-88-2]
Mode of toxic action; Electro(nucleo)phile. (ref. ID; 3327)
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 3327, 7772)

[2-Nitroresorcinol]
Chemical fromula; C6H5NO4
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[Nitrosobenzene] CAS[586-96-9]
Chemical formula; C6H5NO
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)


[Nitrotoluene]

2-Nitrotoluene
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

3-Nitrotoluene
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

4-Nitrotoluene
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)


[3-Nitro-1,2,4-triazol-5-ol]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[3-Nitro-1,2,4-triazol-5-one]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[1-Octanol] CAS[111-87-5] UN3082
= Octyl alcochol
Chemical formula; CH3(CH2)6CH2OH
Chemical characteristics; 1-octanol/water partition coefficient calculated by MEDCHEM CLOGP version 3.53 (log Kow) 3.15. (ref. ID; 631)
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 631, 990, 6839, 7772)

[Pentachloronitrobenzene] CAS[608-93-5]
Trade name; Quintozene (J, I, B) or Quintozen: Brassicol, Earthcide, PCNB, Pentagen, Pentrone, Terraclor
Chemical formula; C6Cl5NO2
Purpose for use; Fungicide.
Toxicity; LD50 (oral) rat > 12000 mg/kg
Test organisms;
Protozoa: Colpidium campylum (ref. ID; 6784)
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[Pentafluoronitrobenzene]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[Pentryl]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[RDX]
1,3,5-Trinitro-1,3,5-triazacyclohexane (RDX) CAS[121-82-4] (ref. ID; 4958, 6817)
1,3,5-Trinitro-1,3,5,7-triazacyclohexane (ref. ID; 6865)
Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) (ref. ID; 6927)
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
Oligochaeta: Eisenia andrei (ref. ID; 4958, 6817, 6927)
Oligochaeta: Lumbricus terrestris (ref. ID; 4958)

[2,3,5,6-Tetrachloro-1,4-dinitrobenzene]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

[1,2,3,5-Tetrachloro-4-nitrobenzene]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)


[Tetrachloronitrobenzene]

2,3,4,5-Tetrachloronitrobenzene
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

2,3,5,6-Tetrachloronitrobenzene
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)


[2,3,4,6-Tetrafluoronitrobenzene] CAS[314-41-0]
Chemical formula; C6HF4NO2
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[Tetryl]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[2,4,5-Trichloro-1,3-dinitrobenzene]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

[2,4,6-Trichloro-1,3-dinitrobenzene]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

[1,2,3-Trichloro-5-nitrobenzene] CAS[20098-48-0]
Chemical formula; C6H2Cl3NO2
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[1,2,4-Trichloro-3-nitrobenzene]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[1,2,4-Trichloro-6-nitrobenzene]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)


[Trichloronitrobenzene]

2,3,4-Trichloronitrobenzene CAS[17700-09-3]
= 1-Nitro-2,3,4-trichlorobenzene
Chemical formula; Cl3C6H2NO2
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

2,4,5-Trichloronitrobenzene CAS[89-69-0]
= 1,2,4-Trichloro-5-nitrobenzene
Chemical formula; Cl3C6H2NO2
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

2,4,6-Trichloronitrobenzene CAS[18708-70-8]
= 1,3,5-Trichloro-2-nitrobenzene
Chemical formula; Cl3C6H2NO2
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)


[1,2,3-Trifluoro-4-nitrobenzene]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[2,4,6-Trimethylnitrobenzene]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

[1,3,5-Trinitrobenzene]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[2,4,6-Trinitrophenol] CAS[88-89-1] UN0154
Chemical formula; (O2N)3C6H2OH
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

[1,3,5-Trinitrosobenzene]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[1,3,5-Trinitroso-1,3,5-triazine]
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)


[Trinitrotoluene]

2,3,4-Trinitrotoluene
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

2,3,6-Trinitrotoluene
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

2,4,5-Trinitrotoluene
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

2,4,6-Trinitrotoluene CAS[118-96-7]
Biotransformation of TNT has been demonstrated in bacteria, fungi, plants, mammals and humans. The ntiro-reduction of TNT into monoamino metabolites ([2-ADNT] and [4-ADNT] and then into diamino metabolites [2,4-DANT] and [2,6-DANT]) was the major metabolic pathway observed. (ref. ID; 7030)
Purpose for use; Energetic compounds.
TNT has been identified in soil at sites related to military activities. (ref. ID; 7030)
Toxicity; Mutagenicity/Carcinogenic. (ref. ID; 7030)
Test organisms;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
Oligochaeta: Eisenia andrei (ref. ID; 4958, 6817, 6865, 7030)
Oligochaeta: Enchytraeus albidus (ref. ID; 6130)
Oligochaeta: Lumbricus terrestris (ref. ID; 4958)