Benzene & benzene derivatives

[Benzene] CAS[71-43-2] UN1114

= Benzol

Chemical formula

C6H6

Chemical characteristics

Lipophilicity log P 1.95. (ref. ID; 6959)

Purpose for use

Organic solvent.

Toxicity

Carcinogens. (ref. ID; 868)

Test organisms

Rotifera: Brachionus calyciflorus (ref. ID; 127)
Rotifera: Dicranophorus forcipatus (ref. ID; 2381)
Rotifera: Lecane hamata (ref. ID; 6861, 7164)
Rotifera: Lecane luna (ref. ID; 6861, 7164)
Rotifera: Lecane quadridentata (ref. ID; 6861, 7164)
Oligochaeta: Eisenia fetida (ref. ID; 6959, 7012, 7163, 7182)
Nematoda: Panagrellus redivivus (ref. ID; 868)

[Chrysoidine hydrochloride] CAS[532-82-1]

= 2,4-diaminoazobenzene hydrochloride

Chemical formula

C12H12N4/HCl

Purpose for use

Dye.

Toxicity

LD50 (oral): rat 1650 mg/kg.

Test organisms

Green algae (formerly including protozoa): Chlamydomonas reinhardtii (ref. ID; 6926)

[Cumene] CAS[98-82-8]

= Isopropylbenzene, (1-Methylethyl)benzene

Chemical formula

C6H5CH(CH3)2

Test organisms

Rotifera: Dicranophorus forcipatus (ref. ID; 2381)

[Diaminobenzene]

= Phenylenediamine, Benzenediamine

Chemical formula

C6H8N2

Isomer: 1,2- (= o-) CAS[95-54-5]
Isomer: 1,3- (= m-) CAS[108-45-2]
Isomer: 1,4- (= p-) CAS[106-50-3]

1,2-Diaminobenzene

Chemical characteristics

Log Kow 0.86. (ref. ID; 449)

Toxicity

LD50 (oral): rat 1070 mg/kg.

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 449)

1,4-Diaminobenzene

Chemical characteristics

Log Kow 0.53. (ref. ID; 449)

Toxicity

LD50 (oral): rat 80 mg/kg.

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 449)

[Bromonitrobenzene]

Chemical formula

BrC6H4NO2

Isomer: 2- CAS[577-19-5] UN2732
Isomer: 3- CAS[585-79-5] UN2732
Isomer: 4- CAS[586-78-7] UN2732

2-Bromonitrobenzene CAS[577-19-5] UN2732

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

3-Bromonitrobenzene CAS[585-79-5] UN2732

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

4-Bromonitrobenzene CAS[586-78-7] UN2732

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

[2,5-Dibromonitrobenzene] CAS[3460-18-2]

Chemical formula

C6H3Br2NO2

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

[6-Bromo-1,3-dinitrobenzene]

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

[4-Butoxynitrobenzene]

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

[Butylbenzene] CAS[104-51-8]

Chemical formula

C6H5(CH2)3CH3

Chemical characteristics

1-octanol-partition coefficients (log Kow) 4.26. (ref. ID; 7004)

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 7004)

[Chlorobenzene] CAS[108-90-7] UN1134

Chemical formula

C6H5Cl

Chemical characteristics

Lipophilicity log P 2.84. (ref. ID; 6959)

Purpose for use

Organic solvent.

Test organisms

Oligochaeta: Eisenia fetida (ref. ID; 6959, 7163)

[Dichlorobenzene]

Chemical formula

C6H4Cl2

Isomer: 1,2- (= o-) CAS[95-50-1]
Isomer: 1,3- (= m-) CAS[541-73-1]
Isomer: 1,4- (= p-) CAS[106-46-7]

1,2-Dichlorobenzene

Trade name

o-dichlorobenzene (J Date registered 12/13/1948, Date registration annulled 1/24/1979): ODB

Chemical characteristics

Lipophilicity log P 3.38. (ref. ID; 6959)
Octanol-water partition coefficient log Kow 3.4. (ref. ID; 6961)

Purpose for use

Insecticide, herbicide.

Test organisms

Oligochaeta: Eisenia fetida (ref. ID; 6959, 7163)
Oligochaeta: Community. (ref. ID; 6961, 6969)

1,3-Dichlorobenzene

Chemical characteristics

Octanol-water partition coefficient log Kow 3.4. (ref. ID; 6961)

Test organisms

Oligochaeta: Community. (ref. ID; 6961, 6969)

1,4-Dichlorobenzene

Trade name

p-dichlorobenzene: Di-chloride, PDB, Paracide

Chemical characteristics

Octanol-water partition coefficient log Kow 3.4. (ref. ID; 6961)

Purpose for use

Insecticide.

Toxicity

LD50 (oral): rat 500-5000 mg/kg, mouse 2950 mg/kg.

Test organisms

Oligochaeta: Community. (ref. ID; 6961, 6969)

[Trichlorobenzene]

Chemical formula

C6H3Cl3

Isomer: 1,2,3- CAS[87-61-6] UN2811
Isomer: 1,2,4- CAS[120-82-1] UN2321
Isomer: 1,3,5- CAS[108-70-3] UN2321

1,2,3-Trichlorobenzene

Chemical characteristics

Octanol-water partition coefficient log Kow 4.1. (ref. ID; 6961)

Test organisms

Protozoa: Spirostomum ambiguum (ref. ID; 6983)
Oligochaeta: Eisenia andrei (ref. ID; 6978, 7018)
Oligochaeta: Lumbricus rubellus (ref. ID; 6978)
Oligochaeta: Community. (ref. ID; 6961, 6969)

1,2,4-Trichlorobenzene

Chemical characteristics

Lipophilicity log P 4.26. (ref. ID; 6959)
Octanol-water partition coefficient log Kow 4.0. (ref. ID; 6961)

Mode of toxic action

Narcotic. (ref. ID; 3327)

Test organisms

Protozoa: Spirostomum ambiguum (ref. ID; 6983)
Protozoa: Tetrahymena pyriformis (ref. ID; 3327)
Oligochaeta: Allolobophora tuberculata (ref. ID; 7159, 7163)
Oligochaeta: Eisenia andrei (ref. ID; 2170)
Oligochaeta: Eisenia fetida (ref. ID; 6959, 7159)
Oligochaeta: Eudrilus eugeniae (ref. ID; 7159, 7163)
Oligochaeta: Perionyx excavatus (ref. ID; 7159, 7163)
Oligochaeta: Community (ref. ID; 6961, 6969)

1,3,5-Trichlorobenzene

Chemical characteristics

Octanol-water partition coefficient log Kow 4.2. (ref. ID; 6961)

Test organisms

Oligochaeta: Eisenia andrei (ref. ID; 2170)
Oligochaeta: Community (ref. ID; 6961, 6969)

[Tetrachlorobenzene]

Chemical formula

C6H2Cl4

Isomer: 1,2,3,4- CAS[634-66-2]
Isomer: 1,2,4,5- CAS[95-94-3]

1,2,3,4-Tetrachlorobenzene

Chemical characteristics

Octanol-water partition coefficient log Kow 4.5. (ref. ID; 6961)
Log Kow 4.635. (ref. ID; 7018)

Test organisms

Oligochaeta: Eisenia andrei (ref. ID; 2170, 7018, 7082)
Oligochaeta: Limnodrilus hoffmeisteri (ref. ID; 6780)
Oligochaeta: Tubifex tubifex (ref. ID; 6780)
Oligochaeta: Community. (ref. ID; 6961, 6969)

1,2,4,5-Tetrachlorobenzene

Chemical characteristics

Octanol-water partition coefficient log Kow 4.5. (ref. ID; 6961)

Test organisms

Oligochaeta: Eisenia andrei (ref. ID; 2170)
Oligochaeta: Limnodrilus hoffmeisteri (ref. ID; 6780)
Oligochaeta: Tubifex tubifex (ref. ID; 6780)
Oligochaeta: Community (ref. ID; 6961, 6969)

[Pentachlorobenzene] CAS[608-93-5]

Chemical formula

C6HCl5

Chemical characteristics

Log P 5.03. (ref. ID; 507)
Octanol-water partition coefficient log Kow 4.9. (ref. ID; 6961)
Log Kow 5.183. (ref. ID; 7018)

Test organisms

Oligochaeta: Eisenia andrei (ref. ID; 2170, 7018, 7082, 7158)
Oligochaeta: Limnodrilus hoffmeisteri (ref. ID; 507, 6780)
Oligochaeta: Tubifex tubifex (ref. ID; 507, 6780)
Oligochaeta: Community (ref. ID; 6961, 6969)
Microcosm: Tuibificid worms (ref. ID; 6960)

[Hexachlorobenzene] CAS[118-74-1]

Trade name

HCB: Amatin, Anti-Carie, Granozol, Perchlorobenzene

Chemical formula

C6Cl6

Chemical characteristics

Log P 5.74. (ref. ID; 507)
Lipophilicity Kow 5.7. (Rippen, 1991). Log P 6.18. (ref. ID; 6959)
Octanol-water partition coefficient log Kow 5.5. (ref. ID; 6961)
Log Kow 5.731. (ref. ID; 7018)

Purpose for use

Fungicide.

Toxicity

LD50 (oral): rat 10000 mg/kg.

Test organisms

Protozoa: Colpidium campylum (ref. ID; 6784)
Oligochaeta: Eisenia andrei (ref. ID; 2170, 7018, 7082, 7158)
Oligochaeta: Eisenia fetida (ref. ID; 6959)
Oligochaeta: Limnodrilus hoffmeisteri (ref. ID; 507, 3110, 6670, 6780)
Oligochaeta: Tubifex tubifex (ref. ID; 507, 3110, 6670, 6780)
Oligochaeta: Community (ref. ID; 6961, 6969)
Nematoda: Panagrellus redivivus (ref. ID; 868)
Microcosm: Tuibificid worms (ref. ID; 6960)

[Chloronitrobenzene]

Chemical formula

ClC6H4NO2

Isomer: 2- CAS[88-73-3] UN1578
Isomer: 3-
Isomer: 4- CAS[100-00-5] UN1578

2-Chloronitrobenzene

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

3-Chloronitrobenzene

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

4-Chloronitrobenzene

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

[1-Chloro-2,4-dinitrobenzene (CDNB)] CAS[97-00-7]

= 2,4-Dinitrochlorobenzene

Chemical formula

C6H3ClN2O4

Test organisms

Protozoa: Spirostomum ambiguum (ref. ID; 6983)
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
Rotifera: Brachionus calyciflorus (ref. ID; 127)

[6-Chloro-1,3-dinitrobenzene]

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 6709)

[Dichloronitrobenzene]

Chemical formula

C6H3Cl2NO2

Isomer: 2,3- CAS[3209-22-1] UN1578
Isomer: 2,4- CAS[611-06-3] UN1578
Isomer: 2,5- CAS[89-61-2] UN1578
Isomer: 3,4- CAS[99-54-7]
Isomer: 3,5- CAS[618-62-2] UN1578

2,3-Dichloronitrobenzene

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

2,4-Dichloronitrobenzene

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

2,5-Dichloronitrobenzene

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

3,4-Dichloronitrobenzene

= 1,2-Dichloro-4-nitrobenzene

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

3,5-Dichloronitrobenzene

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

[1,3-Dichloro-4,6-dinitrobenzene] CAS[3698-83-7]

Mode of toxic action

Electro(nucleo)phile. (ref. ID; 3327)

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 3327, 7772)

[4,6-Dichloro-1,2-dinitrobenzene]

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

[Trichloronitrobenzene]

Chemical formula

Cl3C6H2NO2

Isomer: 2,3,4- CAS[17700-09-3]
Isomer: 2,4,5- CAS[89-69-0]
Isomer: 2,4,6- CAS[18708-70-8]

2,3,4-Trichloronitrobenzene

= 1-Nitro-2,3,4-trichlorobenzene

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

2,4,5-Trichloronitrobenzene

= 1,2,4-Trichloro-5-nitrobenzene

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

2,4,6-Trichloronitrobenzene

= 1,3,5-Trichloro-2-nitrobenzene

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

[2,4,5-Trichloro-1,3-dinitrobenzene]

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

[2,4,6-Trichloro-1,3-dinitrobenzene]

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

[1,2,3-Trichloro-5-nitrobenzene] CAS[20098-48-0]

Chemical formula

C6H2Cl3NO2

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[1,2,4-Trichloro-3-nitrobenzene]

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[1,2,4-Trichloro-6-nitrobenzene]

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[Tetrachloronitrobenzene]

Chemical formula

Cl4C6HNO2

Isomer: 2,3,4,5-
Isomer: 2,3,5,6- CAS[117-18-0]

2,3,4,5-Tetrachloronitrobenzene

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

2,3,5,6-Tetrachloronitrobenzene

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

[2,3,5,6-Tetrachloro-1,4-dinitrobenzene]

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

[1,2,3,5-Tetrachloro-4-nitrobenzene]

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[Pentachloronitrobenzene] CAS[608-93-5]

Trade name

Quintozene (J, I, B) or Quintozen: Brassicol, Earthcide, PCNB, Pentagen, Pentrone, Terraclor

Chemical formula

C6Cl5NO2

Purpose for use

Fungicide.

Toxicity

LD50 (oral): rat >12000 mg/kg.

Test organisms

Protozoa: Colpidium campylum (ref. ID; 6784)
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[3-Chloro-4-fluoronitrobenzene]

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[2,3,4,6-Tetrafluoronitrobenzene] CAS[314-41-0]

Chemical formula

C6HF4NO2

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[1,2-Dicyanobenzene]

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 6709)

[Ethylbenzene] CAS[100-41-4] UN1175

Chemical formula

C2H5C6H5

Chemical characteristics

Lipophilicity Log P 3.15. (ref. ID; 6959)

Test organisms

Rotifera: Dicranophorus forcipatus (ref. ID; 2381)
Oligochaeta: Eisenia fetida (ref. ID; 6959, 7163)

[4-Ethylnitrobenzene] CAS[100-12-9]

Chemical formula

C8H9NO2

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

[1-Fluoro-3-iodo-5-nitrobenzene]

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[4-Fluoronitrobenzene] CAS[350-46-9] UN2811

Chemical formula

FC6H4NO2

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

[1-Fluoro-2-nitrobenzene]

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[1-Fluoro-3-nitrobenzene]

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[4,5-Difluoro-2-dinitrobenzene]

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[2,5-Difluoronitrobenzene]

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[Pentafluoronitrobenzene]

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[1,2,3-Trifluoro-4-nitrobenzene]

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[4-Hydroxyazobenzene] CAS[1689-82-3]

Chemical characteristics

1-octanol/water partition coefficients log P 3.18. (ref. ID; 1897)

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 1897)

[6-Iodo-1,3-dinitrobenzene]

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

[Dimethoxybenzene]

Chemical formula

C6H4(OCH3)2

Isomer: o- CAS[91-16-7] = Veratrole
Isomer: m- CAS[151-10-0]
Isomer: p- CAS[150-78-7] = Hydroquinone dimethyl ether

o-Dimethoxybenzene

Test organisms

Oligochaeta: Eisenia foetida (ref. ID; 7182)

m-Dimethoxybenzene

Test organisms

Oligochaeta: Eisenia foetida (ref. ID; 7182)

p-Dimethoxybenzene

Test organisms

Oligochaeta: Eisenia foetida (ref. ID; 7182)

[3-Methyl-4-bromonitrobenzene]

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

[3-Methyl-2-chloronitrobenzene]

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 6709)

[1-Methyl-3,5-dihydroxybenzene]

Test organisms

Oligochaeta: Eisenia foetida (ref. ID; 7182)

[5-Methyl-1,2-dinitrobenzene]

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

[6-Methyl-1,3-dinitrobenzene]

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

[1,2-Dimethyl-4-nitrobenzene]

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[1,3-Dimethyl-2-nitrobenzene] CAS[81-20-9] UN1665

Chemical formula

(CH3)2C6H3NO2

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

[2,3-Dimethylnitrobenzene]

= 1,2-Dimethyl-3-nitrobenzene CAS[83-41-0] UN1665

Chemical formula

(CH3)2C6H3NO2

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

[2,4,6-Trimethylnitrobenzene]

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

[Nitrobenzene] CAS[98-95-3] UN1662

Chemical formula

C6H5NO2

Chemical characteristics

Lipophilicity log P 1.85. (ref. ID; 6959)

Purpose for use

Organic solvent.

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)
Oligochaeta: Allolobophora tuberculata (ref. ID; 7159, 7163)
Oligochaeta: Eisenia fetida (ref. ID: 6959, 7159, 7163)
Oligochaeta: Eudrilus eugeniae (ref. ID; 7159, 7163)
Oligochaeta: Perionyx excavatus (ref. ID; 7159, 7163)

[4-Nitro-1,2-diaminobenzene] CAS[99-56-9]

Chemical characteristics

Log Kow 1.09. (ref. ID; 449)

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 449)

[Dinitrobenzene]

Chemical formula

C6H4(NO2)2

Isomer: 1,2- (= o-) CAS[528-29-0] UN3443
Isomer: 1,3- (= m-) CAS[99-65-0] UN3443
Isomer: 1,4- (= p-) CAS[100-25-4] UN3443

1,2-Dinitrobenzene

Chemical characteristics

Log Kow 1.67. (ref. ID; 449)

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 449, 6709, 7772)

1,3-Dinitrobenzene

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

1,4-Dinitrobenzene

Chemical characteristics

Log Kow 1.60. (ref. ID; 449)

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 449, 6709, 7772)

[1,3,5-Trinitrobenzene]

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[1,2-Dinitro-4,5-dichlorobenzene]

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)

[2,4-Dinitrofluorobenzene] CAS[70-34-8]

= 1-Fluoro-2,4-dinitrobenzene

Test organisms

Protozoa: Spirostomum ambiguum (ref. ID; 6983)

[2,4-Dinitro-1-fluorobenzene]

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[Nitrosobenzene] CAS[586-96-9]

Chemical formula

C6H5NO

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[Dinitrosobenzene]

Isomer: 1,3-
Isomer: 1,4-

1,3-Dinitrosobenzene

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

1,4-Dinitrosobenzene

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

[1,3,5-Trinitrosobenzene]

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 7772)