Since we humans are exposed to various kinds of environmental chemicals, their safety have been concerned. Health risk assessment on various chemicals have been proceeded, however, shortage of information on neurotoxicity of chemicals is remarkable, thus their impact have hardly been elucidated. I am working on development of new methods and arrangement of test batteries for evaluating neurotoxicity and application of them to various chemicals to provide neurotoxicity data of various environmental chemicals. My special interest is on development and application of new behavioral methods and test batteries for evaluating neurotoxicity of environmental chemicals and providing neurotoxicity data using those methods. I am also interested in good effects of environmental chemicals on mental function, and working on neuropharmacological effects of aromatic and/or odor chemicals.
Career
1980~1984 College of Biological Sciences, Second Cluster of College, University of Tsukuba
1984~1986 Graduate School of Environmental Sciences, University of Tsukuba
1986~1990 Graduate School of Medicine, Gunnma University
1990~ National Institute for Environmental Studies
1995~1997 University of Virginia (Visiting Researcher)
Japanese Pharmacological Society (JPS),The pharmaceutical society of japan,Japanese Society of Neuropsychopharmacology,Japan Society of Endocrine Disrupters Research (JSEDR),Japanese Society for Chronobiology,Japanese Society of Behavioral Medicine
Research Subject
Fiscal Year: 2024
26829 : Research project on the health hazard assessment considering the real-life environment and vulnerability
Fiscal Year: 2023
26420 : Research project on the health hazard assessment considering the real-life environment and vulnerability
Fiscal Year: 2022
25973 : Research project on the health hazard assessment considering the real-life environment and vulnerability
Fiscal Year: 2021
25517 : Research on the health hazard assessment considering the real-life environment and vulnerability
25625 : A fundamental study for evaluating health impact of environmental factors
25650 : A study on psychoactive effects of plant-derived substances for developing healthy aroma environment
Fiscal Year: 2020
25099 : Research Program on Health and Environmental Safety
25141 : Research Project on Health Impacts of Chemicals on Children and Future Generations
25218 : A study on psychoactive effects of plant-derived substances for developing healthy aroma environment
25236 : A Fundamental Study for Evaluating Health Impact of Environmental Factors
Fiscal Year: 2019
24696 : Research Program on Health and Environmental Safety
24721 : Research Project on Health Impacts of Chemicals on Children and Future Generations
24926 : A Fundamental Study for Evaluating Health Impact of Environmental Factors
24927 : A study on psychoactive effects of plant-derived substances for developing healthy aroma environment
Fiscal Year: 2018
24304 : Research project on health impacts of chemicals on children and future generations
24355 : Research program on health and environmental safety
24447 : A study on psychoactive effects of plant-derived substances for developing healthy aroma environment
24531 : A fundamental study for evaluating health impact of environmental factors
Fiscal Year: 2017
23824 : Research project on health impacts of chemicals on children and future generations
23847 : Research program on health and environmental safety
23975 : A fundamental study for evaluating health impact of environmental factors
23976 : A study on psychoactive effects of plant-derived substances for developing healthy aroma environment
Fiscal Year: 2016
23414 : Research program on health and environmental safety
23415 : Research project on health impacts of chemicals on children and future generations
23598 : A study on psychoactive effects of plant-derived substances for developing healthy aroma environment
23659 : A fundamental study for evaluating health impact of environmental factors
Fiscal Year: 2015
23110 : A study on systematization of neurobehavioral methods for evaluating health effects of environmental chemicals
23111 : A study on psychoactive effects of plant-derived substances for developing healthy aroma environment
Fiscal Year: 2014
22880 : A study on systematization of neurobehavioral methods for evaluating health effects of environmental chemicals
22884 : A study on psychoactive effects of plant-derived substances for developing healthy aroma environment
Fiscal Year: 2013
22461 : A study on psychoactive effects of plant-derived substances for developing healthy aroma environment
22462 : A study on systematization of neurobehavioral methods for evaluating health effects of environmental chemicals
Fiscal Year: 2012
22031 : A study on psychoactive effects of plant-derived substances for developing healthy aroma environment
22034 : A study on systematization of neurobehavioral methods for evaluating health effects of environmental chemicals
Fiscal Year: 2011
21405 : Research for monitoring and risk assessment of cyanotoxin microcystin
21556 : Neuropharmacological study for effects of nicotine and menthol on depression symptom
21557 : A study on psychoactive effects of plant-derived substances for developing healthy aroma environment
21564 : A study on systematization of neurobehavioral methods for evaluating health effects of environmental chemicals
Fiscal Year: 2010
21071 : Study on establishment of behavioral tests system for evaluation of health effects of environmental chemicals
21072 : Neuropharmacological study for effects of nicotine and menthol on depression symptom
21073 : A study on psychoactive effects of plant-derived substances for developing healthy aroma environment
Fiscal Year: 2009
20509 : Quantification of ferritin, an iron storage protein in vivo and its application to molecular imaging
20632 : Study on establishment of behavioral tests system for evaluation of health effects of environmental chemicals
20633 : Neuropharmacological study for effects of nicotine and menthol on depression symptom
20634 : A study on psychoactive effects of plant-derived substances for developing healthy aroma environment
Fiscal Year: 2008
20103 : Quantification of ferritin, an iron storage protein in vivo and its application to molecular imaging
20225 : Study on establishment of behavioral tests system for evaluation of health effects of environmental chemicals
Fiscal Year: 2007
10477 : Behavioral toxicological study for developmental effects of diphenylarsinic acid
10605 : Study on establishment of behavioral tests system for evaluation of health effects of environmental chemicals
10723 : Quantification of ferritin, an iron storage protein in vivo and its application to molecular imaging
Fiscal Year: 2006
10081 : Study on the metabolism underlying brain function using an ultra high field multinuclear MRI system
10221 : Behavioral toxicological study for developmental effects of diphenylarsinic acid
10338 : Study on establishment of behavioral tests system for evaluation of health effects of environmental chemicals
Fiscal Year: 2005
9337 : MRI, behavioral and neurochemical study on the effect of endocrine disrupting chemicals on the nervous system.
9341 : Study on the effect of endocrine disrupting chemicals to the reproductive and immune system.
9388 : Study on establishment of behavioral tests system for evaluation of health effects of environmental chemicals
9554 : Study on the metabolism underlying brain function using an ultra high field multinuclear MRI system
Fiscal Year: 2004
8972 : MRI, behavioral and neurochemical study on the effect of endocrine disrupting chemicals on the nervous system.
8976 : Study on the effect of endocrine disrupting chemicals to the reproductive and immune system.
9022 : Study on establishment of behavioral tests system for evaluation of health effects of environmental chemicals
9305 : Study on the metabolism underlying brain function using an ultra high field multinuclear MRI system
Fiscal Year: 2003
8675 : Development of ultrahighfieldmultinuclear MRI system for human measurements
8689 : MRI, behavioral and neurochemical study on the effect of endocrine disrupting chemicals on the nervous system.
8693 : Study on the effect of endocrine disrupting chemicals to the reproductive and immune system.
8740 : Study on establishment of behavioral tests system for evaluation of health effects of environmental chemicals
Fiscal Year: 2002
8459 : Development of ultra high field multinuclear MRI system for human measurements
8474 : MRI, behavioral and neurochemical study on the effect of endocrine disrupting chemicals on the nervous system.
8522 : Study on establishment of behavioral tests system for evaluation of health effects of environmental chemicals
8538 : Study on the effect of endocrine disrupting chemicals to the reproductive and immune system.
Fiscal Year: 2001
8236 : Development of ultra high field multinuclear MRI system for human measurements
8252 : MRI, behavioral and neurochemical study on the effect of endocrine disrupting chemicals on the nervous system.
8284 : Study on establishment of behavioral tests system for evaluation of health effects of environmental chemicals
Presenter :
Satou T., Matsuura M., Takahashi M., Umezu T., Hayashi S., Sadamoto K., Koike K. Title : , Flavour and Fragrance Journal, 26(6):416-420 (2011)
Presenter :
Satou T., Matsuura M., Takahashi M., Umezu T., Hayashi S., Sadamoto K., Koike K. Title : , Flavour and Fragrance Journal, 26(6):416-420 (2011)
Presenter : Umezu T., Sano T., Hayashi J., Yoshikawa Y. Name of Society : WCP2018 KYOTO / 18th WORLD CONGRESS OF BASIC AND CLINICAL PHARMACOLOGY (2018) Name of Proceedings : WCP2018 KYOTO / 18th WORLD CONGRESS OF BASIC AND CLINICAL PHARMACOLOGY/MICEnavi Program and Proceedings
Research Presentation Rapid transport of diphenylarsinic acid into brain through blood-brain barrier as revealed by microdialysis combined with LCMSMS
Presenter :
Shibata Y., Umezu T., Hosoya T., Takagi M. , Nakamiya K. Name of Society : Metallomics 2013 (2013) Name of Proceedings : Abstracts
Research Presentation Behavioral pharmacology of plant-derived substances(15): Effects of mentol on extracellular dopamine,serotonine,norepinephrine and their metabolites in mouse striatum.Comparison with effects of bupropion,methylphenidate and cffeine
Presenter : UMEZU Toyoshi Name of Society : 79th Annu.Meet.Jpn.Pharmacol.Soc. (2006) Name of Proceedings : Abstracts
Research Presentation Behavioral pharmacology of plant-derived subustances(14): Interaction between menthol and nicotine on ambulation in mice
Presenter : Umezu T., Morita M. Name of Society : 78th Annu.Meet.Jpn.Pharm.Soc. (2005) Name of Proceedings : J.Pharm.Sci., 97(Suppl.1)
Research Presentation Behaviral pharmacology of plant-derived substances (13): anticonflict effects of lavender oil and identification of its active constituent
Presenter : Umezu T., Ito H., Morita M., Nagano K. Name of Society : 24th CINP Congr.2004 (2004) Name of Proceedings : Abstracts, 7(Suppl.1)
Research Presentation Behavioral pharmacology of plant-derived substances(10)-behavioral effects of 2-phenethyl alcohol and citronellol in mice.Comparison with diazepam
Presenter : Umezu T., Sato C.(*1), Yamada M.(*1), Sakaniwa M.(*1), Morita M. Name of Society : 76th Annu.Meet.Jpn.Pharmacol.Soc. (2003) Name of Proceedings : J.Pharmacol.Sci., 91(Suppl.1)(Suppl.1):91
Behavioral pharmacology of plant-derived substances(8): effects of plant-derived essential oils on the discrete shuttle type avoidance response in mice
Presenter : Umezu T. Name of Society : 75th Annu.Meet.Jpn.Pharmocol.Soc. (2002) Name of Proceedings : Jpn.J.Pharmacol., 88(Suppl.1)
Rapid transport of diphenylarsinic acid into brain through blood-brain barrier as revealed by microdialysis combined with LCMSMS
Presenter :
Shibata Y., Umezu T., Hosoya T., Takagi M. , Nakamiya K. Name of Society : Metallomics 2013 (2013) Name of Proceedings : Abstracts
Behavioral pharmacology of plant-derived substances(15): Effects of mentol on extracellular dopamine,serotonine,norepinephrine and their metabolites in mouse striatum.Comparison with effects of bupropion,methylphenidate and cffeine
Presenter : UMEZU Toyoshi Name of Society : 79th Annu.Meet.Jpn.Pharmacol.Soc. (2006) Name of Proceedings : Abstracts
Behavioral pharmacology of plant-derived subustances(14): Interaction between menthol and nicotine on ambulation in mice
Presenter : Umezu T., Morita M. Name of Society : 78th Annu.Meet.Jpn.Pharm.Soc. (2005) Name of Proceedings : J.Pharm.Sci., 97(Suppl.1)
Behaviral pharmacology of plant-derived substances (13): anticonflict effects of lavender oil and identification of its active constituent
Presenter : Umezu T., Ito H., Morita M., Nagano K. Name of Society : 24th CINP Congr.2004 (2004) Name of Proceedings : Abstracts, 7(Suppl.1)
Behavioral pharmacology of plant-derived substances(10)-behavioral effects of 2-phenethyl alcohol and citronellol in mice.Comparison with diazepam
Presenter : Umezu T., Sato C.(*1), Yamada M.(*1), Sakaniwa M.(*1), Morita M. Name of Society : 76th Annu.Meet.Jpn.Pharmacol.Soc. (2003) Name of Proceedings : J.Pharmacol.Sci., 91(Suppl.1)(Suppl.1):91
Presenter : Umezu T., Sano T., Hayashi J., Yoshikawa Y. Name of Society : WCP2018 KYOTO / 18th WORLD CONGRESS OF BASIC AND CLINICAL PHARMACOLOGY (2018) Name of Proceedings : WCP2018 KYOTO / 18th WORLD CONGRESS OF BASIC AND CLINICAL PHARMACOLOGY/MICEnavi Program and Proceedings