Ref ID : 428
Rasmussen, L., Toftlund, H., and Suhr Jessen, P.; Tetrahymena. Adaptation to high iron. Exp.Cell Res. 153:236-239, 1984
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Fe-starved ciliates Tetrahymena thermophila cease to multiply at Fe(III) concentrations above 10 microM in a synthetic nutrient medium lacking a good iron chelator such as citrate. If, however, the Fe(III) concentration is gradually increased over a series of subcultivations the cells will tolerate up to 300 microM Fe(III). Our experiments rule out the possibility of genetic selection of Fe-tolerant clones and suggest a physiological type of adaptation.