Ref ID : 4198

I. Joan Lorch, H.B. Kim, and Kwang W. Jeon; Symbiont-Induced Strain-Specific Lethal Effect in Amoebae. J.Protozool. 32(4):745-746, 1985

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The cytosol fraction of a symbiont-bearing strain of Amoeba proteus exerted a lethal effect when injected into symbiont-free amoebae of the original strain. The lethal factor appeared to be a protein with a molecular weight of over 200,000. While the effect of the lethal factor on the nucleus was reversible, the host cytoplasm was permanently damaged so that it could not form a viable cell when combined with a normal nucleus.