Nitroaromatics and derivatives
Nitroaromatic compounds and their numerous derivatives are of use as explosives and propellants both in the military and industory. A number of studies have shown that nitro compounds, their metabolites of environmental transformation and by-products of their synthesis or incomplete combustion are harmful for the biosphere due to their toxicity. For instance, toxic effects in humans after dermal, oral or respiratory exposure include gastrointestinal, neurological and reproductive disorders, cirrhosis of the liver, hepatitis, cataracts, respiratory and skin irritation, nephrotoxicity, and hematological defects. More over, nitroaromatic compounds are widey used in medicine, industry and agriculture. (ref. ID; 7772)
[2-Amino-4-chloro-5-nitrophenol]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)
[2-Amino-6-chloro-4-nitrophenol] CAS[6358-09-4]
Chemical formula
C6H5ClN2O3
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[4-Amino-3,5-dinitrobenzamide]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[2-Amino-4,6-dinitrotoluene (2-ADNT)] CAS[35572-78-2]
Chemical characteristics
2,4,6-Trinitrotoluene (TNT) metabolites.
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[3-Amino-2,6-dinitrotoluene]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[2-Amino-4-nitrophenol] CAS[99-57-0]
Chemical formula
H2NC6H3(NO2)OH
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)
[4-Amino-2-nitrophenol]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)
[ANTA (3-Nitro-1,2,4-triazol-5-amine)]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[2-Bromo-4,6-dinitroaniline] CAS[1817-73-8]
Chemical formula
C6H4BrN3O4
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[6-Bromo-1,3-dinitrobenzene]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)
[4-Bromo-2-fluoro-6-nitrophenol]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[2-Bromo-2'-hydroxy-5'-nitroacetanilide]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[Bromonitrobenzene]
See: Benzene & benzene derivatives
[4-Butoxynitrobenzene]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)
[4-(tert)Butyl-2,6-dinitrophenol] CAS[4097-49-8]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[4-Chloro-2,6-dinitroaniline]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[6-Chloro-2,4-dinitroaniline] CAS[3531-19-9] UN2237
Chemical formula
ClC6H3(NO2)2NH2
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[1-Chloro-2,4-dinitrobenzene (CDNB)] CAS[97-00-7]
= 2,4-Dinitrochlorobenzene
Chemical formula
C6H3ClN2O4
Test organisms
Protozoa: Spirostomum ambiguum (ref. ID; 6983)
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
Rotifera: Brachionus calyciflorus (ref. ID; 127)
[4-Chloro-3,5-dinitrobenzonitrile]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[5-Chloro-2,4-dinitrotoluene]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[3-Chloro-4-fluoronitrobenzene]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[2-Chloromethyl-4-nitrophenol]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)
[2-Chloro-5-nitroaniline] CAS[6283-25-6] UN2237
Chemical formula
ClC6H3(NO2)NH2
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[2-Chloro-6-nitroaniline]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[2-Chloro-5-nitrobenzaldehyde] CAS[6361-21-3]
Chemical formula
ClC6H3(NO2)CHO
Chemical characteristics
Log Ko/w 2.25. (ref. ID; 7771)
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7771, 7772)
[2-Chloro-6-nitrobenzaldehyde]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[4-Chloro-6-nitrobenzaldehyde]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[5-Chloro-2-nitrobenzamide]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[Chloronitrobenzene]
See; Benzene & benzene derivatives
[4-Chloro-3-nitrobenzonitrile] CAS[939-80-0]
Chemical formula
C7H3ClN2O2
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[4-Chloro-6-nitromcresol]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)
[2-Chloro-4-nitrophenol] CAS[619-08-9] UN1759
Chemical formula
ClC6H3(NO2)OH
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)
[4-Chloro-2-nitrophenol] CAS[89-64-5] UN2811
Chemical formula
ClC6H3(NO2)OH
Chemical characteristics
Logarithm of 1-octanol/water partition coefficient log Kow 2.46. (ref. ID; 6981)
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)
[4-Chloro-3-nitrophenol] CAS[610-78-6]
Chemical formula
C6H4ClNO3
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[2,4-Chloro-6-nitrophenol]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)
[2-Chloro-6-nitrotoluene] CAS[83-42-1] UN43457
Chemical formula
CH3C6H3(NO2)Cl
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[4-Chloro-2-nitrotoluene] CAS[89-59-8] UN3457
Chemical formula
ClC6H3(NO2)CH3
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[CL-14]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[CL-20]
= 2,4,6,8,10,12-Hexanitro-2,4,6,8,10,12-hexazaisowurtzitane CAS[135285-90-4], = Nitramine
Trade name
CL-20
Purpose for use
Energetic compound (polycyclic nitramine explosive).
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
Oligochaeta: Eisenia andrei (ref. ID; 4572)
[Diaminoazofurazan]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[2,4-Dibromo-6-nitroaniline]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[2,5-Dibromonitrobenzene] CAS[3460-18-2]
Chemical formula
C6H3Br2NO2
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)
[2,6-Dibromo-4-nitrophenol] CAS[99-28-5]
Chemical formula
C6H3Br2NO3
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)
[2,4-Dichloro-6-nitroaniline] CAS[2683-43-4]
Chemical formula
C6H4Cl2N2O2
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[4,5-Dichloro-2-nitroaniline]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[1,3-Dichloro-4,6-dinitrobenzene] CAS[3698-83-7]
Mode of toxic action
Electro(necleo)phile. (ref. ID; 3327)
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 3327, 7772)
[4,6-Dichloro-1,2-dinitrobenzene]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)
[Dichloronitrobenzene]
See: Benzene & benzene derivatives
[2,6-Dichloro-4-nitrophenol] CAS[618-80-4]
Chemical formula
Cl2C6H2(NO2)OH
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[1,5-Difluoro-2,4-nitroaniline]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[2,5-Difluoronitrobenzene]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[4,5-Difluoro-2-dinitrobenzene]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[2,6-Diiodo-4-nitrophenol] CAS[305-85-1]
Chemical formula
C6H3I2NO3
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)
[1,2-Dimethyl-4-nitrobenzene]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[1,3-Dimethyl-2-nitrobenzene] CAS[81-20-9] UN1665
Chemical formula
(CH3)2C6H3NO2
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)
[2,3-Dimethylnitrobenzene]
= 1,2-Dimethyl-3-nitrobenzene CAS[83-41-0] UN1665
Chemical formula
(CH3)2C6H3NO2
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)
[Dimethylnitroterephthalate]
= Dimethyl Nitroterephthalate CAS[5292-45-5]
Chemical fromula
C10H9NO6
Mode of toxic action
Diester. (ref. ID; 3327)
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 3327, 7772)
[Dinitroaniline]
Chemical formula
(O2N)2C6H3NH2
- Isomer: 2,4- CAS[97-02-9] UN1596
- Isomer: 2,6-
- Isomer: 3,5- CAS[618-87-1] UN1596
2,4-Dinitroaniline
Test organisms
Protozoa: Spirostomum ambiguum (ref. ID; 6983)
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
Protozoa: Tetrahymena thermophila (ref. ID; 6010)
2,6-Dinitroaniline
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
3,5-Dinitroaniline
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[Dinitrobenzene]
See; Benzene & benzene derivatives
[3,5-Dinitrobenzonitrile] CAS[4110-35-4]
Chemical formula
C7H3N3O4
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[3,4-Dinitrobenzyl alcohol]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[3,5-Dinitrobenzyl alcohol] CAS[71022-43-0]
Chemical fromula
C7H6N2O5
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[2,6-Dinitro-4-cresol]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)
[3,5-Dinitro-p-cresol]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[4,6-Dinitro-2-cresol] CAS[534-52-1] UN1598
= DNOC
Chemical formula
C7H6N2O5
Purpose for use
Pesticide.
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 3554, 6709, 7772)
[1,2-Dinitro-4,5-dichlorobenzene]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)
[2,4-Dinitro-5-fluoroaniline]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[2,4-Dinitro-1-fluorobenzene]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[Dinitroglycouril]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[2,4-Dinitroimidazole]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[Dinitrophenol]
Chemical formula
(O2N)2C6H3OH
- Isomer: 2,3-
- Isomer: 2,4- CAS[51-28-5] UN1320
- Isomer: 2,5- CAS[329-71-5] UN1320
- Isomer: 2,6- CAS[573-56-8]
- Isomer: 3,4-
2,3-Dinitrophenol
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)
2,4-Dinitrophenol
Chemical characteristics
Lipophilicity log P 1.53. (ref. ID; 6959)
Purpose for use
Fungicide.
Toxicity
2,4-Dinitrophenol uncouples oxidative phosphorylation without blocking oxygen consumption by dissipating the electrochemical gradient across the inner mitochondrial membrane. In early studies on Tetrahymena, DNP was reported to affect dose-depended respiration, phosphate accumulation, endocytosis, fine structure after a 1-hr exposure, and final cell density a 96-hr exposure. Effects were enhanced when DNP was tested at acid pH pointing towards the undissociated DNP molecule being active state. (ref. ID; 7348)
Test organisms
Green algae (formerly including protozoa): Chlamydomonas reinhardtii (ref. ID; 4556)
Protozoa: Spirostomum ambiguum (ref. ID; 6984)
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7348, 7772)
Oligochaeta: Eisenia fetida (ref. ID; 6959)
2,5-Dinitrophenol
Test organisms
Protozoa: Spirostomum ambiguum (ref. ID; 6984)
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)
2,6-Dinitrophenol
Test organisms
Protozoa: Spirostomum ambiguum (ref. ID; 6984)
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)
3,4-Dinitrophenol
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)
[Dinitrosobenzene]
See; Benzene & benzene derivatives
[1,3-Dinitro-5-nitroso-1,3,5-triazine]
Test organisms
;
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[1,3-Dinitroso-5-nitro-1,3,5-triazine]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[Dinitrotoluene]
- Isomer: 2,3-
- Isomer: 2,5-
2,3-Dinitrotoluene
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
2,5-Dinitrotoluene
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[EGDN]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[4-Ethoxy-2-nitroaniline]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[4-Ethylnitrobenzene] CAS[100-12-9]
Chemical formula
C8H9NO2
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)
[Ethyl-4-nitrobenzoate]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[1-Fluoro-3-iodo-5-nitrobenzene]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[4-Fluoronitrobenzene] CAS[350-46-9] UN2811
Chemical formula
FC6H4NO2
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)
[1-Fluoro-2-nitrobenzene]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[1-Fluoro-3-nitrobenzene]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[3-Fluoro-4-nitrophenol] CAS[394-41-2]
Chemical formula
C6H4FNO3
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[5-Fluoro-2-nitrophenol] CAS[446-36-6]
Chemical formula
C6H4FNO3
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)
[FOX-7]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[HBT]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[HMX]
= Octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (HMX) CAS[2691-41-0], = 1,3,5,7-Tetranitro-1,3,5,7-tetrazacyclo-octane (ref. ID; 6865)
Purpose for use
High melting explosive.
Toxicity
This explosive is toxic to some aquatic organisms, including fathead minnows (Pimephales promelas) and the freshwater microcrustacean Daphnia magna, and some terrestrial organisms including mice and rats. But, HMX is not toxic to the bioluminescent bacteria Vibrio fisheri and is not cytotoxic or mutagenic to bacterial and mammalian cells in aqueous solutions of HMX. (ref. ID; 6115)
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
Oligochaeta: Eisenia andrei (ref. ID; 4958, 6115, 6817)
Oligochaeta: Lumbricus terrestris (ref. ID; 4958)
[1-Hydroxylamino-3,5-dinitro-1,3,5-triazine]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[1-Hydroxylamino-3,5-dinitroso-1,3,5-triazine]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[2-Hydroxylamino-4,6-dinitrotoluene]
Chemical characteristics
2,4,6-Trinitrotoluene (TNT) metabolites.
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[4-Hydroxylamino-2,6-dinitrotoluene]
Chemical characteristics
2,4,6-Trinitrotoluene (TNT) metabolites.
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[1-Hydroxylamino-3-nitroso-5-nitro-1,3,5-triazine]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[3-Hydroxy-4-nitrobenzaldehyde]
Chemical characteristics
Log Ko/w 1.47. (ref. ID; 7771)
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7771, 7772)
[4-Hydroxy-3-nitrobenzaldehyde] CAS[3011-34-5]
Chemical formula
C7H5NO4
Chemical characteristics
Log Ko/w 1.48. (ref. ID; 7771)
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7771, 7772)
[5-Hydroxy-2-nitrobenzaldehyde] CAS[42454-06-8]
Chemical formula
C7H5NO4
Chemical characteristics
Log Ko/w 1.75. (ref. ID; 7771)
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7771, 7772)
[6-Iodo-1,3-dinitrobenzene]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)
[K-55]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[3-Methyl-4-bromonitrobenzene]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)
[Methyl-4-chloro-2-nitrobenzoate] CAS[42087-80-9]
Mode of toxic action
Electro(necleo)phile. (ref. ID; 3327)
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 3327, 7772)
[5-Methyl-1,2-dinitrobenzene]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)
[6-Methyl-1,3-dinitrobenzene]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)
[3-Methyl-2,4-dinitrophenol]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[3-Methyl-4,6-dinitrophenol]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[2-Methyl-4-nitroaniline] CAS[99-52-5] UN2660
Chemical formula
CH3C6H3(NO2)NH2
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[4-Methyl-2-nitroaniline] CAS[89-62-3]
Chemical formula
CH3C6H3(NO2)NH2
Chemical characteristics
Log Kow 1.82. (ref. ID; 449)
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 449, 7772)
[Methyl-4-nitrobenzoate]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[2-Methyl-3-nitrophenol]
= 3-Nitro-o-cresol CAS[119-33-5] UN2446
Chemical formula
CH3C6H3(NO2)OH
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[2-Methyl-5-nitrophenol] CAS[5428-54-6] UN2446
Chemical formula
C7H7NO3
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[3-Methyl-2-nitrophenol] CAS[4920-77-8]
Chemical formula
C7H7NO3
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[3-Methyl-4-nitrophenol] CAS[2581-34-2] UN2446
Chemical formula
C7H7NO3
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)
[4-Methyl-2-nitrophenol]
= 2-Nitro-p-cresol CAS[119-33-5] UN2446
Chemical formula
CH3C6H3(NO2)OH
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)
[4-Methyl-3-nitrophenol] CAS[2042-14-0] UN2446
Chemical formula
C7H7NO3
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)
[5-Methyl-2-nitrophenol] CAS[700-38-9] UN2446
Chemical formula
C7H7NO3
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[3-Nitroacetophenone]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)
[Nitroaniline]
See; Aniline and -aniline
[Nitrobenzaldehyde]
See; -aldehyde
[Nitrobenzamide]
See; -benzamide
[Nitrobenzene]
See; Benzene & benzene derivatives
[Nitrobenzoic acid]
See; benzoic acid & -benzoic acid
[Nitrobenzonitrile]
See; Benzonitrile and -benzonitrile
[Nitrobenzyl alcohol]
Chemical formula
C7H7NO3
- Isomer: 2-
- Isomer: 3-
- Isomer: 4-
2-Nitrobenzyl alcohol
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
3-Nitrobenzyl alcohol
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
4-Nitrobenzyl alcohol
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
4-Nitrobenzyl chloride
Chemical fromula
H6ClNO2
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[Nitrobiphenyl]
Chemical formula
C12H9NO2
- Isomer: 2- CAS[86-00-0]
- Isomer: 3-
2-Nitrobiphenyl
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
3-Nitrobiphenyl
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[4-Nitro-catechol]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[4-Nitrodiphenylamine] CAS[836-30-6]
= N-phenyl-4-nitroaniline
Chemical fromula
C12H10N2O2
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[Nitroglycerin] CAS[55-63-0]
= Glycerol trinitrate
Chemical formula
C3H5N3O9
Purpose for use
Blasting explosive.
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[3-Nitro-2-hydroxybenzaldehyde]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[2-Nitroimino-5-nitro-hexahydro-1,3,5-triazine]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[4-Nitrophenetole]
Chemical formula
C8H9NO3
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[Nitrophenol]
See; Phenols and derivatives
[4-Nitrophenylacetonitrile]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[4-Nitrophenyl-phenyl-ether] CAS[620-88-2]
Mode of toxic action
Electro(nucleo)phile. (ref. ID; 3327)
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 3327, 7772)
[2-Nitroresorcinol]
Chemical fromula
C6H5NO4
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[Nitrosobenzene] CAS[586-96-9]
Chemical formula
C6H5NO
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[Nitrotoluene]
See; Toluene and -toluene
[3-Nitro-1,2,4-triazol-5-ol]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[3-Nitro-1,2,4-triazol-5-one]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[1-Octanol] CAS[111-87-5] UN3082
= Octyl alcochol
Chemical formula
CH3(CH2)6CH2OH
Chemical characteristics
1-octanol/water partition coefficient calculated by MEDCHEM CLOGP version 3.53 (log Kow) 3.15. (ref. ID; 631)
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 631, 990, 6839, 7772)
[2-Octanol] CAS[123-96-6] or CAS[4128-31-8] (ref. ID; 631)
= Capryl alcochol, Methylhexylcarbinol
Chemical formula
CH3(CH2)5CH(OH)CH3
Chemical characteristics
1-octanol/water partition coefficient calculated by MEDCHEM CLOGP version 3.53 (log Kow) 2.77. (ref. ID; 631)
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 631)
[3-Octanol] CAS[589-98-0] or CAS[20296-29-1] (ref. ID; 631)
Chemical formula
CH3(CH2)4CH(OH)CH2CH3
Chemical characteristics
1-octanol/water partition coefficient calculated by MEDCHEM CLOGP version 3.53 (log Kow) 2.77. (ref. ID; 631)
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 631)
[Pentachloronitrobenzene] CAS[608-93-5]
Trade name
Quintozene (J, I, B) or Quintozen: Brassicol, Earthcide, PCNB, Pentagen, Pentrone, Terraclor
Chemical formula
C6Cl5NO2
Purpose for use
Fungicide.
Toxicity
LD50 (oral): rat >12000 mg/kg.
Test organisms
Protozoa: Colpidium campylum (ref. ID; 6784)
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[Pentafluoronitrobenzene]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[Pentryl]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[RDX]
= 1,3,5-Trinitro-1,3,5-triazacyclohexane (RDX) CAS[121-82-4] (ref. ID; 4958, 6817), = 1,3,5-Trinitro-1,3,5,7-triazacyclohexane (ref. ID; 6865),
= Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) (ref. ID; 6927)
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
Oligochaeta: Eisenia andrei (ref. ID; 4958, 6817, 6927)
Oligochaeta: Lumbricus terrestris (ref. ID; 4958)
[2,3,5,6-Tetrachloro-1,4-dinitrobenzene]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)
[1,2,3,5-Tetrachloro-4-nitrobenzene]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[Tetrachloronitrobenzene]
See; Benzene & benzene derivatives
[2,3,4,6-Tetrafluoronitrobenzene] CAS[314-41-0]
Chemical formula
C6HF4NO2
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[Tetryl]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[2,4,5-Trichloro-1,3-dinitrobenzene]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)
[2,4,6-Trichloro-1,3-dinitrobenzene]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)
[1,2,3-Trichloro-5-nitrobenzene] CAS[20098-48-0]
Chemical formula
C6H2Cl3NO2
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[1,2,4-Trichloro-3-nitrobenzene]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[1,2,4-Trichloro-6-nitrobenzene]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[Trichloronitrobenzene]
See; Benzene & benzene derivatives
[1,2,3-Trifluoro-4-nitrobenzene]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[2,4,6-Trimethylnitrobenzene]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)
[1,3,5-Trinitrobenzene]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[2,4,6-Trinitrophenol] CAS[88-89-1] UN0154
Chemical formula
(O2N)3C6H2OH
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 6709, 7772)
[1,3,5-Trinitrosobenzene]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[1,3,5-Trinitroso-1,3,5-triazine]
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
[Trinitrotoluene]
- Isomer: 2,3,4-
- Isomer: 2,3,6-
- Isomer: 2,4,5-
- Isomer: 2,4,6- CAS[118-96-7]
2,3,4-Trinitrotoluene
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
2,3,6-Trinitrotoluene
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
2,4,5-Trinitrotoluene
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
2,4,6-Trinitrotoluene
Biotransformation of TNT has been demonstrated in bacteria, fungi, plants, mammals and humans. The ntiro-reduction of TNT into monoamino metabolites ([2-ADNT] and [4-ADNT] and then into diamino metabolites [2,4-DANT] and [2,6-DANT]) was the major metabolic pathway observed. (ref. ID; 7030)
Purpose for use
Energetic compounds.
TNT has been identified in soil at sites related to military activities. (ref. ID; 7030)
Toxicity
Mutagenicity/Carcinogenic. (ref. ID; 7030)
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
Oligochaeta: Eisenia andrei (ref. ID; 4958, 6817, 6865, 7030)
Oligochaeta: Enchytraeus albidus (ref. ID; 6130)
Oligochaeta: Lumbricus terrestris (ref. ID; 4958)