Latest Update:2017/10/05 16:16:29

TIN-TIN-Win-Shwe

TIN-TIN-Win-Shwe
Researcher Name
TIN-TIN-Win-Shwe
Div (Section) name/title
Center for Health and Environmental Risk Research(Health Effect Assessment Section)/Senior Researcher
Research Subject
Analysis of developmental neurotoxicity of environmental chemicals in mice
Degree(s)
M.D., Ph.D (Medical Science)
Professional Qualification(s)
Medicine,Physiology,Biochemistry
Environmental Speciality Field
hazardous chemical substance,atmospheric pollutants,volatile organic compounds
Keyword(s)
in vivo microdialysis in rats and mice,HPLC assay for neurotransmitter assessment,Radioimmunoassay for hormone measurement,Gonadectomization for male and female rats,Intracardiac catheterization and blood sampling,Guide cannula implatation in various brain regions,Dissection and sampling of various brain regions,RNA isolation, DNA synthesis and real-time PCR,Learning behavior assessment by Morris water maze ,Brain perfusion and section using microtome
Brief Description of Research
I have studied the effects of environmental toxic chemicals like volatile organic compounds (VOC) and environmental pollutants like nanoparticles on brain neurotransmitter system and memory-function related gene expression in adult mouse hippocampus and olfactory bulb. I have demonstrated neurotoxic effects of toluene exposure in BALB/c adult mice and two congenic adult mice strains by measuring excitatory amino acid neurotransmitter levels in the hippocampus (Win-Shwe et al., 2007a; 2009). Moreover, I have also shown that the effect of toluene exposure on N-methyl-D-aspartate (NMDA) receptor subunit expression in hippocampus of wild type and nude mice (Win-Shwe et al., 2007c). Regarding nanoparticles, I have already reported that the effects of nanoparticle-rich diesel exhaust on spatial learning and memory function-related gene expression in the mouse hippocampus (Win-Shwe et al., 2008) and on extracellular glutamate level and NMDA receptor subunit expression in the mouse olfactory bulb (Win-Shwe et al., in press). However, I have not examined the developmental neurotoxicity of these substances yet, then, up to now, the mechanism by which toluene or nanoparticle exposure during the brain growth spurt affected cognitive functions and glutamate toxicity are unknown. These situations prompt me to examine the effect and mechanism of toluene or nanoparticle exposure during developmental period with a new novel experimental design. Recently, serious public problems concerning food contamination with agrichemicals occurred in Japan and as where. Organophosphate pesticides (OPs) are used worldwide especially South-East Asia including Myanmar. Among OPs, diazinon is used in order to combat insects and arthropods in agricultural industries. Children may be exposed to that OP by getting the residues on foods or by contacting the contaminated surfaces in houses and gardens. However, there is no study reporting the effects of developmental exposure to diazinon on glutamatergic neurotransmitter system in in vivo experiments. Therefore, using our new experimental model, I emphasize to examine the developmental neurotoxicity following exposure to diazinon.
The current aims of research are to investigate the effect of prenatal and/or
postnatal exposure to nanoparticles, diazinon and toluene on glutamatergic
neurotransmission, related gene expression and learning ability in adult mice and to investigate the possible mechanisms of these three substances. Microdialysis is a novel technique allowing an in vivo measurement of endogenous and exogenous substances in the extracellular fluid surrounding a microdialysis probe implanted into an organ or tissue. Hippocampus is important for spatial memory, but its integrity is also necessary for recognition memory. Novel object recognition task relies on the mouse’s natural exploratory behavior and it can be used without stress, technical difficulty and time consuming. Therefore, in the present research, I try to combine these two techniques to establish an experimental model to examine extracellular neurotransmitters and learning ability simultaneously. I expect to measure the extracellular glutamate levels in the hippocampus of adolescent and adult mice while monitoring learning ability in sequentially in different doses following prenatal and/or postnatal exposure to environmental toxicant. Then, I can point out the vulnerable period or critical window for susceptibility of individuals to toxic chemical exposure. I can evaluate the relationship between neurotransmitter system and learning performance. I can also find out the possible mechanism of action of environmental toxicant by using receptor blocker or measuring transporter level. After establishment of this new experimental design, it can be used for assessing the other environmental toxic chemicals in various brain regions for examining higher brain functions.
Career
4/1/1979−3/25/1986---Institute of Medicine 1, Yangon, Myanmar [M. D] (Completion of Medicine, Surgery, Pediatric, Obstetric and Gynecology)
1/4/1987−31/3/1990---Medical Research Officer, WHO project, “Study of the effects of water supply, socio-economic status and sanitation on health in Myanmar rural areas”, Department of Medical Research, Ministry of Health, Yangon, Myanmar
1/4/1990−31/3/1995---Assistant Lecturer, Department of Physiology, Institute of Medicine 1, Yangon, Myanmar
4/1/1992−3/25/1995---Institute of Medicine 1, Yangon, Myanmar [M. Med. Sc] Department of Physiology, Institute of Medicine 1, Yangon, Myanmar
1/4/1995−31/3/1998---Lecturer, Department of Physiology, Institute of Medicine 1, Yangon, Myanmar
4/1/1999−3/31/2003---Yokohama City University Graduate School of Medicine, Department of Physiology, [Ph. D]
1/11/2003−31/3/2006---Post-doctoral Fellow, Department of Health Sciences, NIES
1/4/2006−31/3/2008---JSPS Post-doctoral Fellowship for Foreign Researchers, Research Center for Environmental Risk, NIES
1/4/2008−30/3/2011---Research Fellow, Research Center for Environmental Risk, NIES
1/4/2011-up to present---Researcher, Center for Environmental Health Sciences, NIES



Membership of Academic Society
The Japan Neuroscience Society ,American Society for Neuroscience,Japanese Society of Immunotoxicology,Japanese Society for Atmospheric Environment,The Japanese Society of Toxicology
Research Subject
  • Fiscal Year: 2017
    • 23824 : Research project on health impacts of chemicals on children and future generations
    • 23847 : Research program on health and environmental safety
    • 23899 : The relationship between the gut microbiota and modern diseases
    • 23900 : Impact of brominated flame retardants in obesity and obesity-related metabolic disorders
    • 23926 : Investigation on validity of the proposed evaluation method on the effects of chemical substances to developmental disorders using non-invasive MR measurements
    • 23949 : Comprehensive and systematic study for control/eradication of allergic diseases via environmental and medical approaches
    • 23975 : A fundamental study for evaluating health impact of environmental factors
    • 24003 : A novel approach for evaluation of environmental pollutant-induced developmental neurotoxicity using non-invasive MRI technique
    • 24007 : Study of the possible biological effects and medical applications of intermediate frequency electromagnetic fields
    • 24010 : Creation of network toward the establishment of environmental research foundation in Myanmar
  • Fiscal Year: 2016
    • 23414 : Research program on health and environmental safety
    • 23415 : Research project on health impacts of chemicals on children and future generations
    • 23525 : Impact of brominated flame retardants in obesity and obesity-related metabolic disorders.
    • 23579 : Establishment of multidisciplinary strategy toward comprehensive understanding of developmental neurotoxicity induced by environmental chemicals in house dust
    • 23586 : Investigation on validity of the proposed evaluation method on the effects of chemical substances to developmental disorders using non-invasive MR measurements
    • 23605 : A novel approach for evaluation of environmental pollutant-induced developmental neurotoxicity using non-invasive MRI technique
    • 23607 : Creation of network toward the establishment of environmental research foundation in Myanmar
    • 23657 : Study of the possible biological effects and medical applications of intermediate frequency electromagnetic fields
    • 23659 : A fundamental study for evaluating health impact of environmental factors
    • 23743 : Comprehensive and systematic study for control/eradication of allergic diseases via environmental and medical approaches
  • Fiscal Year: 2015
    • 23018 : Mechanism and evaluation system of the developmental health effects of environmental factors
    • 23082 : Impact of brominated flame retardants in obesity and obesity-related metabolic disorders.
    • 23116 : Establishment of multidisciplinary strategy toward comprehensive understanding of developmental neurotoxicity induced by environmental chemicals in house dust
    • 23243 : Study of the possible biological effects and medical applications of intermediate frequency electromagnetic fields
    • 23244 : Establishment of neonatal animal model for early detection of environmental pollutant induced-learning disability
    • 23245 : Biological impact evaluation of exposure to electromagnetic fields emitted by mobile phones
    • 23272 : Investigation on validity of the proposed evaluation method on the effects of chemical substances to developmental disorders using non-invasive MR measurements
    • 23277 : Establishment of an international cooperation for promoting arsenic research
  • Fiscal Year: 2014
    • 22606 : Mechanism and evaluation system of the developmental health effects of environmental factors
    • 22706 : Impact of brominated flame retardants in obesity and obesity-related metabolic disorders.
    • 22722 : Establishment of an international cooperation for promoting arsenic research
    • 22802 : Establishment of multidisciplinary strategy toward comprehensive understanding of developmental neurotoxicity induced by environmental chemicals in house dust
    • 22891 : Health Assessment of PAMAM dendrimer
    • 22948 : Health effects of secondary organic aerosols derived from diesel exhaust.
    • 22980 : Establishment of neonatal animal model for early detection of environmental pollutant induced-learning disability
    • 22981 : Biological impact evaluation of exposure to electromagnetic fields emitted by mobile phones
  • Fiscal Year: 2013
    • 22190 : Mechanism and evaluation system of the developmental health effects of environmental factors
    • 22238 : Establishment of neonatal animal model for early detection of environmental pollutant induced-learning disability
    • 22239 : Biological impact evaluation of exposure to electromagnetic fields emitted by mobile phones
    • 22279 : Studies on the effects of environmental chemicals on nervous and immunological systems during developmental period
    • 22314 : Impact of brominated flame retardants in obesity and obesity-related metabolic disorders.
    • 22402 : Health Assessment of PAMAM dendrimer
    • 22544 : Establishment of an international cooperation for promoting arsenic research
    • 22570 : Health effects of secondary organic aerosols derived from diesel exhaust.
  • Fiscal Year: 2012
    • 21761 : Mechanism and evaluation system of the developmental health effects of environmental factors
    • 21808 : Studies on the effects of environmental chemicals on nervous and immunological systems during developmental period
    • 22009 : Health Assessment of PAMAM dendrimer
    • 22149 : Health effects of secondary organic aerosols derived from diesel exhaust.
    • 22237 : Evaluation of the biological effects of intermediate frequency magnetic field exposure during developmental stages
  • Fiscal Year: 2011
    • 21273 : Studies on the effects of environmental chemicals on nervous and immunological systems during developmental period
    • 21319 : Mechanism and evaluation system of the developmental health effects of environmental factors
    • 21432 : Risk assessment of inhaled nanoparticle rich diesel exhaust focusing the impacts on brain, liver, kidney, and reproductive organs
    • 21434 : Analysis of usefulness of a mouse model for sensitivity in evaluating the toxicity of environmental chemicals
  • Fiscal Year: 2010
    • 20967 : Risk assessment of inhaled nanoparticle rich diesel exhaust focusing the impacts on brain, liver, kidney, and reproductive organs
    • 20977 : Health risk assessment methods of environmental chemicals that cause sensitivity
    • 20979 : Analysis of usefulness of a mouse model for sensitivity in evaluating the toxicity of environmental chemicals
  • Fiscal Year: 2006
    • 10288 : Establishing a new sensitive model to assess harmful effects on memory function following exposure to environmental chemicals
  • Fiscal Year: 2005
    • 9590 : Establishment of in vivo microdialysis study of brain functions during various stages of learning behavior in mouse model
  • Fiscal Year: 2004
    • 9326 : Determination of neuroimmune functions in mouse exposed to harmful toxic chemicals by in vivo microdialysis
Research Result (Publication)
  • all
  • Original Paper
  • Review
  • Book
  • Other Publications
  • Environmental Chemical Substances in Relation to Neurodevelopmental Disorders: A Systematic Literature Review
    Presenter : Sone H., Win-Shwe T.T., Qin X.Y., Akanuma H., Imanishi S.
    Title : , Learning Disabilities (2012)
Research Result (Presentation)
  • all
  • Research Presentation
  • Research Lecture
  • Research Presentation
    Effects of exposure to bisphenol A on memory function and neuroimmune biomarkers in allergic asthmatic mice
    Presenter : Tin-Tin-Win-Shwe, Yanagisawa R., Koike E., Takano H
    Name of Society : 24th Annual Meeting of the Japanese Society of Immunotoxicology (2017)
    Name of Proceedings : Abstracts, 84
  • Research Presentation
    Evaluation of neurotoxicity by air pollutant exposure using animal model
    Presenter : Tin-Tin-Win-Shwe, Fujitani Y., Hirano S.
    Name of Society : 44th Annual Meeting of the Japan Society of Toxicology (2017)
    Name of Proceedings : Abstracts, S90
  • Research Presentation
    Developmental exposure to tetrabromobisphenol A (TBBPA) on late onset behavior and neurological biomarkers in adult mice
    Presenter : Tin-Tin-Win-Shwe, Sano K., Isobe T., Kawashima T., Suzuki G., Hashimoto S., Nakayama S., Maekawa F.
    Name of Society : The 40th Annual Meeting of the Japan Neuroscience Society (2017)
    Name of Proceedings : Abstract, 218
  • Research Presentation
    Monitoring of water quality in Inle Lake, Myanmar
    Presenter : Yagishita M., Thandar M., Suzuki T., Tin-Tin-Win-Shwe, Nakajima D., Maung N.S.
    Name of Society : 45th Myanmar Health Research Congress (2017)
    Name of Proceedings : Programme and Abstracts, 20
  • Research Presentation
    Adolescent Exposure to Intermediate-Frequency Magnetic Fields Affects Neurological and Immunological Biomarkers in Young Adult Male Mice
    Presenter : Tin-Tin-Win-Shwe, Ohtani S., Kunugita N., Ushiyama A.
    Name of Society : 45th Myanmar Health Research Congress (2017)
    Name of Proceedings : Abstract, 93
  • Research Presentation
    Social behavior and related gene expressions in fragile X mental retardation 1 (Fmr1) gene knockout and valproic acid (VPA)-induced autism rat models
    Presenter : Tin-Tin-Win-Shwe, Watanabe H.
    Name of Society : 45th Myanmar Health Research Congress (2017)
    Name of Proceedings : Abstract, 88-89
  • Research Presentation
    Effects of perinatal exposure to a phosphate ester flame retardant on novel object recognition ability and memory function-related gene expression in adult mice
    Presenter : Tin-Tin-Win-Shwe, Sano K., Isobe T., Kawashima T., Suzuki G., Hashimoto S., Nakayama S., Maekawa F.
    Name of Society : 45th Myanmar Health Research Congress (2017)
    Name of Proceedings : Abstract, 120
  • Research Presentation
    Establishment of an olfactory-based spatial learning test for neonatal mice and the effects of perinatal exposure to diesel exhaust origin secondary organic aerosol
    Presenter : Tin-Tin-Win-Shwe, Tha-Thu C.K., Moe Y., Fujitani Y., Tsukahara S., Hirano S.
    Name of Society : 11th International Particle Toxicology Conference (2016)
    Name of Proceedings : Abstract, 54
  • Research Presentation
    Comprehensive analysis of house dust using GC×GC-HRTOFMS and in-house software
    Presenter : Ieda T., Hashimoto S., Takazawa Y., Tanabe K., Zushi Y., Shibata Y., Maekawa F., Sano K., Suzuki G., Nakayama S., Isobe T., Tin-Tin-Win-Shwe, Kawashima T.
    Name of Society : DIOXIN2016 (2016)
    Name of Proceedings : Abstracts
  • Research Presentation
    Lactational exposure to benzo[a]pyrene (BaP) on neuroimmune biomarkers in hippocampus of an allergic asthmatic mouse model
    Presenter : Tin-Tin-Win-Shwe, Htike N.T.T., Tsukahara S., Koike E., Yanagisawa R.
    Name of Society : The 39th Annual Meeting of the Japan neuroscience Society (2016)
    Name of Proceedings : Abstract, 189
  • Presenter : Sano K., Yang J., Tin-Tin-Win-Shwe, Maekawa F.
    Name of Society : 10th FENS (the Federation of European Neuroscience Societies) Forum (2016)
    Name of Proceedings : Abstracts, (C076)
  • Research Presentation
    Perinatal exposure to a phosphate ester flame retardant affects memory function and related gene expression in adult mice
    Presenter : Tin-Tin-Win-Shwe, Sano K., Isobe T., Kawashima T., Suzuki G., Hashimoto S., Nakayama S., Maekawa F.
    Name of Society : The 5th Annual Meeting of The Japan Society for Developmental Origins of Health and Disease (DOHaD-Japan) (2016)
    Name of Proceedings : Abstract(P-07), 40
  • Research Presentation
    Evaluation of potentially developmentally neurotoxic chemicals using behavioral testing and neuroendocrinological analysis
    Presenter : Maekawa F., Sano K., Suzuki G., Nakayama S., Isobe T., Tin-Tin-Win-Shwe, Hashimoto S., Kawashima T.
    Name of Society : The 93rd Annual Meeting of the Physiological Society of Japan (2016)
    Name of Proceedings : Proceedings of The 93rd Annual Meeting of the Physiological Society of Japan, 66(supplement1):S73
  • Research Presentation
    Role of toll-like receptor 4 in diesel exhaust origin secondary organic aerosol-induced impaired spatial learning ability in neonatal mice
    Presenter : Tin-Tin-Win-Shwe, Fujitani Y., Watanabe H., Hirano S.
    Name of Society : Society for Neuroscience 2016 (2016)
    Name of Proceedings : Abstract, 61
  • Research Lecture
    In vivo evaluation of a flame retardant having estrogenic activity using mouse model
    Presenter : Sano K., Suzuki G., Htike N.T.T., Morishita M., Tin-Tin-Win-Shwe, Hashimoto S., Kawashima T., Isobe T., Nakayama S., Tsukahara S., Maekawa F.
    Name of Society : Application of Recent Advances in Neuroscience to Environmental Health Research (2016)
    Name of Proceedings : abstract, 1-4
  • Research Presentation
    Novel approach to olfactory-based spatial learning ability for preweaning mice and the effects of early exposure to diesel exhaust origin secondary organic aerosol
    Presenter : Tin-Tin-Win-Shwe, Chaw Kyi Tha Thu, Yadanar Moe, Fujitani Y., Shinji Tsukahara, Maekawa F., Hirano S.
    Name of Society : 44th Myanmar Health Research Congress (2016)
    Name of Proceedings : Abstract, 79
  • Research Presentation
    Monitoring the Environmental Water Samples from South East Asia Countries: Vietnam River and Inle Lake, Myanmar using in vitro Bioassay
    Presenter : Nakajima D., Tin-Tin-Win-Shwe, Shiraishi F., Nguyen Thanh Thao, Nguyen Quang Trung, YAGISHITA M., Sone H., Kadokami K., Nay Soe Maung, Yoneda M.
    Name of Society : 44th Myanmar Health Research Congress, National Institute for Environmental Studies (NIES) and University of Public Heath (UPH) Joint Symposium on - Environmental pollutants and health risk- (our environment, our health) (2016)
    Name of Proceedings : Abstracts
  • Presenter : Tin-Tin-Win-Shwe, Chaw Kyi-Tha Thu, Yadanar Moe, Fujitani Y., Shinji Tsukahara, Nitta H., Hirano S.
    Name of Society : 51st Congress of the European Societies of Toxicology (2015)
    Name of Proceedings : Abstract, 120
  • Presenter : Tin-Tin-Win-Shwe, Fujitani Y., Nohara K., Hirano S.
    Name of Society : 第4回日本DOHaD研究会学術集会 (2015)
    Name of Proceedings : Abtract, 115
  • Presenter : Kurokawa Y., Zeng Y., Tin-Tin-Win-Shwe, Kimura H, Koyama Y, Matsui Y, Hirano S., Sone H.
    Name of Society : 第38回日本神経科学大会(The 38th Annual Meeting of the Japan Neuroscience Society) (2015)
    Name of Proceedings : Abstracts
  • Presenter : Tin-Tin-Win-Shwe, Fujitani Y., Furuyama A., Nitta H., Hirano S.
    Name of Society : 第38回日本神経科学大会 (2015)
    Name of Proceedings : Abstract(3P292), 250
  • Research Presentation
    Developmental exposure to diesel engine exhaust origin secondary organic aerosol on social behavior in adult mice
    Presenter : Tin-Tin-Win-Shwe, Chaw Kyi Tha Thu, Yadanar Moe, Fujitani Y., Tsukahara S, Watanabe H., Hirano S.
    Name of Society : 8th Federation of the Asian and Oceanian Physiological Society Congress (2015)
    Name of Proceedings : Abstracts, S-A178
  • Research Presentation
    Effect of developmental exposure to acetamiprid on behavioral profiles in mice
    Presenter : Sano K., Yang J., Tin-Tin-Win-Shwe, Nohara K., Maekawa F.
    Name of Society : The 8th congress of the federation of the asian and oceanian physiological societies (2015)
    Name of Proceedings : Abstracts, 65(Supplemental 2):S-A179
  • Presenter : Kurokawa Y., Zeng Y., Zeng Q, Tin-Tin-Win-Shwe, Hirano S., Sone H.
    Name of Society : 37th Annual Meeting of the Japan Neuroscience Society (2014)
    Name of Proceedings : -
  • Research Presentation
    Effects of developmental exposure to diesel engine exhaust origin secondary organic aerosol on social and learning behavior in adult mice
    Presenter : Tin-Tin-Win-Shwe, Maekawa F., Chaw Kyi Tha Thu, Fujitani Y., Yanagisawa R., Furuyama A., Tsukahara S, Nohara K., Nitta H., Hirano S.
    Name of Society : 37th Annual Meeting of the Japan Neuroscience Society (2014)
    Name of Proceedings : Abstract, 131
  • Presenter : Tin-Tin-Win-Shwe, Fujitani Y., Chaw Kyi ThaThu, Furuyama A., Shinji Tsukahara, Nitta H., Hirano S.
    Name of Society : 8th International Congress of Neuroendocrinology 2014 (2014)
    Name of Proceedings : Abstract, 31
  • Presenter : Tin-Tin-Win-Shwe, Yanagisawa R., Koike E., Nitta H., Takano H.
    Name of Society : International Conference of Asian Environmental Chemistry 2014 (2014)
    Name of Proceedings : Abstract, 318
  • Presenter : Tin-Tin-Win-Shwe, Ohtani S., Ushiyama A., Kunugita N.
    Name of Society : International Conference of Asian Environmental Chemistry 2014 (2014)
    Name of Proceedings : Abstract, 325
  • Research Presentation
    Impact of hexabromocyclododecane on lipid and glucose metabolism in high-fat diet-induced obese mice
    Presenter : YANAGISAWA Rie, TIN-TIN-Win-Shwe, KOIKE Eiko
    Name of Society : 49th Congress of the European Societies of Toxicology (2013)
    Name of Proceedings : Abstracts o the 49th Congress of the European Societies of Toxicology (EUROTOX), 221S:S252-S252
  • Research Presentation
    Biodistribution and toxicological effects of intranasally instilled polyamidoamine(PAMAM)dendrimers in BALB/c mouse brain
    Presenter : Tin-Tin-Win-Shwe, Kurokawa Y., Nitta H., Hirano S., Sone H.
    Name of Society : eurotox 2013 (2013)
    Name of Proceedings : Toxicology Letters, 221S(28):S240
  • Research Presentation
    Effects of Developmental Arsenic Exposure on Social Behavior and Neuronal Morphology in Mice
    Presenter : Tin-Tin-Win-Shwe, Aung K.H., Tsukahara S., Nohara K.
    Name of Society : NIES Arsenic Workshop 2013 (2013)
    Name of Proceedings : Abstracts, 22
  • Presenter : Zeng Y., Tin-Tin-Win-Shwe, Kurokawa Y., ZHANG Z., Sone H.
    Name of Society : 環境ホルモン学会第16回研究発表会 (2013)
    Name of Proceedings : なし
  • Research Presentation
    Effects of PAMAM dendrimer exposures during neuronal differentiation from human neural progenitor cells
    Presenter : Zeng Y., Tin-Tin-Win-Shwe, Kurokawa Y., ZHANG.Z.Y., Sone H.
    Name of Society : 細胞アッセイ技術の現状と将来 (2013)
    Name of Proceedings : -
  • Research Presentation
    Intracellular distribution of PAMAM dendrimers in cultured human cells
    Presenter : Kurokawa Y., Tin-Tin-Win-Shwe, Zeng Q, Hirano S., Sone H.
    Name of Society : 6th International Symposium on Nanotechnology, Occupational and Environmental Health (NanOEH) (2013)
    Name of Proceedings : Abstracts, 89
  • Research Presentation
    In vivo and in vitro biological effects and biodistribution of PAMAM-NH2 dendrimers
    Presenter : Tin-Tin-Win-Shwe, Kurokawa Y., Zeng Y., Nitta H., Hirano S., Sone H.
    Name of Society : 6th International Symposium on Nanotechnology,Occupational and Environmental Health (2013)
    Name of Proceedings : Abstracts, 31
  • Research Presentation
    Determinations of PAMAM particles in culture media using SPM techniques
    Presenter : Sone H., Yamazaki M., Zaha H., Zeng Y., Kurokawa Y., Tin-Tin-Win-Shwe, Hirano S.
    Name of Society : 6th International Symposium on Nanotechnology, Occupational and Environmental Health (NanOEH) (2013)
    Name of Proceedings : -
  • Research Presentation
    Effect of PAMAM dendrimers on differentiation of hNPCs: A study of morphological analysis
    Presenter : Zeng Y., Tin-Tin-Win-Shwe, Zeng Q, Kurokawa Y., Hirano S., ZHANG.A.Y, Sone H.
    Name of Society : 6th International Symposium on Nanotechnology,Occupational and Environmental Health (2013)
    Name of Proceedings : Abstracts
  • Research Presentation
    Expression of neuroimmune biomarkers in hypothalamus of allergic mice after early phthalate exposure
    Presenter : Tin-Tin-Win-Shwe, Yanagisawa R., Koike E., Nakajima D., Takano H., Nitta H.
    Name of Society : Annual Meeding of Society of Indoor Environment Japan 2012 (2012)
    Name of Proceedings : Abstracts, 118-119
  • Research Presentation
    Effect of exposure to intermediate frequency magnetic fields on memory function- related gene expression in hippocampus of C57BLmice.
    Presenter : Tin-Tin-Win-Shwe, OHTANI S, USHIYAMA A., Fujimaki H., Nitta H., KUNUGITA N.
    Name of Society : NEUROSCIENCE2012 (2012)
    Name of Proceedings : SOCIETY FOR NEUROSCIENCE MONDAY PROGRAM, 37
  • Research Lecture
    Studies on the effects of toluene exposure on developing immune system
    Presenter : Tin-Tin-Win-Shwe, Kunugita N., Yoshida Y., Fujimaki H.
    Name of Society : 第18回日本免疫毒性学会学術大会 (2011)
    Name of Proceedings : 第18回日本免疫毒性学会学術大会講演要旨集, 64
  • Research Presentation
    Spatial and non-spatial learning performance in mice exposed to nanoparticle-rich diesel exhaust particles
    Presenter : Tin-Tin-Win-Shwe, Kurokawa Y., Fujitani Y., Hirano S., Fujimaki H.
    Name of Society : The 52nd Annual Meeting of Japan Society for Atmospheric Environment (2011)
    Name of Proceedings : Abstracts of The 52nd Annual Meeting of Japan Society for Atmospheric Environment, 293
  • Research Presentation
    Hippocampus-dependent spatial learning deficit in mice following sub-chronic exposure to nanoparticle-rich diesel exhaust
    Presenter : Tin-Tin-Win-Shwe, Fujitani Y., Hirano S., Fujimaki H.
    Name of Society : Eurotox2011 PARIS (2011)
    Name of Proceedings : Program of Eurotox2011 PARIS, 124
  • Research Presentation
    Developmental diazinon exposure induces immune dysfunction in adult mice
    Presenter : Fujimaki H., Tin-Tin-Win-Shwe
    Name of Society : Eurotox2011 PARIS (2011)
    Name of Proceedings : Program of Eurotox2011 PARIS, 131
  • Research Presentation
    Impact of toll-like receptor(TLR)4 on hippocampus-dependent object recognition in early life diazinon exposure
    Presenter : Tin-Tin-Win-Shwe, Fujimaki H.
    Name of Society : Neuroscience 2011 (2011)
    Name of Proceedings : Society for Neuroscience Program, 72
  • Research Presentation
    Toll-like receptor 4-dependent neurotrophin signaling in mouse hippocampus following low-level toluene exposure
    Presenter : Tin-Tin-Win-Shwe, Kunugita N., Yoshida Y., Arashidani K., Fujimaki H.
    Name of Society : 14th Int.Congr.Immunol. (2010)
    Name of Proceedings : Abstracts, 22S(1):i87
  • Research Presentation
    Role of TLR4 signaling pathway in neurotrophin gene expression in mice lungs following low-level toluene exposure
    Presenter : Fujimaki H., Tin-Tin-Win-Shwe, Yoshida Y., Kunugita N., Arashidani K.
    Name of Society : 14th Int.Congr.Immunol. (2010)
    Name of Proceedings : Abstracts, 22S(1):ii136
  • Research Presentation
    Toll-like receptor 4-dependent upregulation of heme oxygenase-1 and anti-inflammatory cytokines in mouse lung following low-level toluene exposure
    Presenter : Fujimaki H., Tin-Tin-Win-Shwe, Yoshida Y., Kunugita N., Arashidani K.
    Name of Society : 12th Int.Congr.Toxicol. (2010)
    Name of Proceedings : Toxicol.Lett., 196S:S193
  • Research Presentation
    Developmental toluene exposure alters neuroimmune markers in the hippocampus of infant mice
    Presenter : Tin-Tin-Win-Shwe, Kunugita N., Yoshida Y., Arashidani K., Fujimaki H.
    Name of Society : 12th Int.Congr.Toxicol. (2010)
    Name of Proceedings : Toxicol.Lett., 196S:S194
  • Research Presentation
    Modulation of the expression of transcription factors mRNAs in spleen from the mice following organophosphate pesticide exposure
    Presenter : Fujimaki H., Tin-Tin-Win-Shwe
    Name of Society : 8th Asia Pac.Congr.Allergy, Asthma Clin.Immunol. (2010)
    Name of Proceedings : Program & Abstracts , 114
  • Research Presentation
    Toll-like receptor 4 mediated neurotrophins, their receptors and signaling pathways in the neuroinflammation of organophosphate pesticides
    Presenter : Tin-Tin-Win-Shwe, Fujimaki H.
    Name of Society : 8th Asia Pac.Congr.Allergy, Asthma Clin.Immunol. (2010)
    Name of Proceedings : Program & Abstracts , 114
  • Research Presentation
    Effect of perinatal toluene exposure at different developmental phases on memory function-related gene expressions in mouse brain
    Presenter : Tin-Tin-Win-Shwe, Kunugita N., Yamamoto S., Arashidani K., Fujimaki H.
    Name of Society : 50th Annu.Meet.Jpn.Soc.Atmos.Environ. (2009)
    Name of Proceedings : Abstracts, 342
  • Research Presentation
    Strain differences influence synaptic plasticity-related gene expression in olfactory bulb of a mouse model of allergy following toluene exposure
    Presenter : Fujimaki H., Tin-Tin-Win-Shwe, Kunugita N., Yamamoto S., Arashidani K.
    Name of Society : 13th Congr.Eur.Fed.Neurol.Soc. (2009)
    Name of Proceedings : Abstracts, 566
  • Research Presentation
    Analysis of neurotoxic effect of nanoparticle-rich diesel exhaust on a mouse brain
    Presenter : Yamamoto S., Tin-Tin-Win-Shwe, Mitsushima D., Fujitani Y., Hirano S., Fujimaki H.
    Name of Society : 13th Congr.Eur.Fed.Neurol.Soc. (2009)
    Name of Proceedings : Abstracts, 325
  • Research Presentation
    A potential role of hippocampal memory function-related gene expression in developmental neurotoxicity of toluene
    Presenter : Tin-Tin-Win-Shwe, Kunugita N., Yamamoto S., Arashidani K., Fujimaki H.
    Name of Society : 13th Congr.Eur.Fed.Neurol.Soc. (2009)
    Name of Proceedings : Abstracts, 324
  • Research Presentation
    Effects of toluene exposure on developmental immunotoxicity in infant mice brain
    Presenter : Tin-Tin-Win-Shwe, Kunugita N., Yamamoto S., Arashidani K., Fujimaki H.
    Name of Society : 16th Annu.Meet.Jpn.Soc.Immunotoxicol. (2009)
    Name of Proceedings : Abstracts, 76
  • Research Presentation
    Targeting in nanoparticle-induced neurotoxicity in mice
    Presenter : Tin-Tin-Win-Shwe, Yamamoto S., Fujitani Y., Hirano S., Fujimaki H.
    Name of Society : 79th Annu.Meet.Jpn.Soc.Hygiene(第79回日本衛生学会学術総会) (2009)
    Name of Proceedings : Jpn.J.Hyg.(日衛誌), 64(2):291
  • Presenter : Tin-Tin-Win-Shwe, Yamamoto S., Fujitani Y., Hirano S., Fujimaki H.
    Name of Society : 31st Annu.Meet.Jpn.Neurosci.Soc. (2008)
    Name of Proceedings : Neurosci.Res., 61(Suppl.1):S258
  • Research Presentation
    Modulation of T cell development by biological and chemical agents neonatal mice
    Presenter : Fujimaki H., Tin-Tin-Win-Shwe, Yamamoto S.
    Name of Society : 7th Annu.Eur.Life Sci.Org.Meet. (2008)
    Name of Proceedings : Abstracts, 126
  • Research Presentation
    Neurotoxic effect of nanoparticle-rich diesel exhaust in the mouse olfactory bulb
    Presenter : Tin-Tin-Win-Shwe, Mitsushima D., Yamamoto S., Fujitani Y., Funabashi T., Hirano S., Fujimaki H.
    Name of Society : 45th Congr.Eur.Soc.Toxicol. (2008)
    Name of Proceedings : Toxicol.Lett., 180S(2008):S206
  • Research Presentation
    Analysis of toluene-induced extracellular amino acid neurotransmitter levels in the hippocampus using in vivo microdialysis in a freely moving mouse model
    Presenter : , NAKAJIMA Daisuke, Tin-Tin-Win-Shwe
    Name of Society : 11th Int.Congr.Toxicol.(Poster Session) (2007)
    Name of Proceedings : Abstracts(CD-R)
  • Research Presentation
    Immunomodulatory role of low-level toluene exposure in mice
    Presenter : , NAKAJIMA Daisuke, Tin-Tin-Win-Shwe
    Name of Society : 11th Int.Congr.Toxicol.(Poster Session) (2007)
    Name of Proceedings : Abstracts(CD-R)
  • Research Presentation
    Effects of nano rich-desel exhaust on lung inflammation related to cell wall components of gram positive bacteria in mice
    Presenter : Yamamoto S., Takeuchi S.(*1), Fujitani Y., Fukushima A., Tin-Tin-Win-Shwe, Fujimaki H.
    Name of Society : 13th Int.Congr.Mucosal Immunol.(Poster Session) (2007)
    Name of Proceedings : Abstracts
  • Research Presentation
    Neuronal synaptic plasticity related gene expressions in the hippocampus and olfactory bulb of mice chronically exposed to low-level toluene
    Presenter : , Tin-Tin-Win-Shwe
    Name of Society : Int.Congr.Toxicol.(Poster Session) (2007)
    Name of Proceedings : Abstracts (CD-R)
  • Research Presentation
    Expression of transcription factor genes for T-cell differentiation in the spleen of C3H/HeN and BALB/c mice by the inhalation of low-level toluene
    Presenter : Fukushima A., Tin-Tin-Win-Shwe, Yamamoto S., Kunugita N.(*1), Yoshida Y.(*1), Arashidani K.(*1), Fujimaki H.
    Name of Society : World Allergy Congr.2007(Poster Session) (2007)
    Name of Proceedings : Abstracts
  • Research Presentation
    Effect of prenatal and postnatal exposure to low-level toluene and peptidoglycan on systematic Th1/Th2 immunity in infant mice
    Presenter : Yamamoto S., Fukushima A., Tin-Tin-Win-Shwe, Hojo R., Yoshida Y.(*1), Kunugita N.(*1), Arashidani K.(*1), Fujimaki H.
    Name of Society : World Allergy Congr.2007(Poster Session) (2007)
    Name of Proceedings : Abstracts
  • Research Presentation
    T cell-mediated neuroprotective response in toxic chemical induced memory-related gene expressions in a mouse hippocampus
    Presenter : , NAKAJIMA Daisuke, Tin-Tin-Win-Shwe
    Name of Society : 23rd Int.Neurotoxicol.Conf.(Poster Session) (2006)
    Name of Proceedings : Abstracts
  • Research Presentation
    Effects of low-level formaldehyde exposure on apoptosis-related molecules in the hippocampus of mice
    Presenter : , Tin-Tin-Win-Shwe
    Name of Society : 23th Int.Neurotoxicol.Conf.(Poster Session) (2006)
    Name of Proceedings : Abstracts
  • Research Presentation
    Role of CD4 T cells in allergic inflammatory responses in mice exposed to low-level toluene
    Presenter : NAKAJIMA Daisuke, Tin-Tin-Win-Shwe
    Name of Society : 1st Jt.Meet.Eur.Natl.Soc.Immunol. (2006)
    Name of Proceedings : Abstracts
  • Research Presentation
    Effect of ultrafine carbon particles on peptidoglycan-induced early pulmonary inflammation in mice
    Presenter : Yamamoto S., Ahmed S., Tin-Tin-Win-Shwe, Fujimaki H.
    Name of Society : 1st Jt.Meet.Eur.Natl.Soc.Immunol.(Poster Session) (2006)
    Name of Proceedings : Abstracts
  • Research Presentation
    Modulated memory-related gene expression in olfactory bulb of low-level toluene-exposed mice
    Presenter : , NAKAJIMA Daisuke, Tin-Tin-Win-Shwe
    Name of Society : 5th Forum Eur.Neurosci.(Poster Session) (2006)
    Name of Proceedings : Abstracts, 3
  • Research Presentation
    Modulated CXCL12 production in mice exposed to low level toluene
    Presenter : , NAKAJIMA Daisuke, Tin-Tin-Win-Shwe
    Name of Society : Int.Cytokine Soc.Conf.2005(Poster Session) (2006)
    Name of Proceedings : Abstracts
  • Research Presentation
    Modulation of pro-inflammatory and neural activity-related gene expression in the olfactory bulb of mice by nasal inhalation of low-level toluene
    Presenter : , KUROKAWA Yoshika, NAKAJIMA Daisuke, Tin-Tin-Win-Shwe
    Name of Society : 8th Int.Congr.Neuroimmunol.(ISNI 2006)(Poster Session) (2006)
    Name of Proceedings : J.Neuroimmunol., 178(S1)
  • Research Presentation
    Role of T cells in toluene-induced memory-related gene expressions in mouse hippocampus
    Presenter : , NAKAJIMA Daisuke, Tin-Tin-Win-Shwe
    Name of Society : 8th Int.Congr.Neuroimmunol.(ISNI 2006) (2006)
    Name of Proceedings : J.Neuroimmunol.
  • Research Presentation
    Synergistic effect of ultrafine carbon particles and staphylococcal cell wall components on early pulmonary inflammation
    Presenter : Yamamoto S., Tin-Tin-Win-Shwe, Fujimaki H.
    Name of Society : 3rd World Congr.Immunopathol.Respir.Allergy (2005)
    Name of Proceedings : Abstracts, 7(1)
  • Research Presentation
    Brain cytokine and chemokine mRNA expressions in mice intranasally instilled with ultrafine carbon black
    Presenter : Tin-Tin-Win-Shwe, Yamamoto S., Fujimaki H.
    Name of Society : 3rd World Congr.Immunopathol.Respir.Allergy (2005)
    Name of Proceedings : Abstracts, 7(1)
  • Research Presentation
    Suppression of IFN-gamma production in mice exposed to low level toluene
    Presenter : , NAKAJIMA Daisuke, Tin-Tin-Win-Shwe
    Name of Society : 3rd World Congr.Immunopathol.Respir.Allergy (2005)
    Name of Proceedings : Abstracts, 7(1)
  • Research Presentation
    Effect of ultrafine carbon particles on lipoteichoic acid-induced early pulmonary inflammation in mice
    Presenter : Yamamoto S., Tin-Tin-Win-Shwe, Ahmed S.,
    Name of Society : Int.Cytokine Soc.Conf.2005(Poster Session) (2005)
    Name of Proceedings : Abstracts
  • Research Presentation
    Role of lymphocytes in toluene-induced chemokine mRNA expression in mouse olfactory bulb
    Presenter : , NAKAJIMA Daisuke, Tin-Tin-Win-Shwe
    Name of Society : Int.Cytokine Soc.Conf.2005(Poster Session) (2005)
    Name of Proceedings : Abstracts
  • Evaluation of neurotoxicity by air pollutant exposure using animal model
    Presenter : Tin-Tin-Win-Shwe, Fujitani Y., Hirano S.
    Name of Society : 44th Annual Meeting of the Japan Society of Toxicology (2017)
    Name of Proceedings : Abstracts, S90
  • Monitoring of water quality in Inle Lake, Myanmar
    Presenter : Yagishita M., Thandar M., Suzuki T., Tin-Tin-Win-Shwe, Nakajima D., Maung N.S.
    Name of Society : 45th Myanmar Health Research Congress (2017)
    Name of Proceedings : Programme and Abstracts, 20
  • Establishment of an olfactory-based spatial learning test for neonatal mice and the effects of perinatal exposure to diesel exhaust origin secondary organic aerosol
    Presenter : Tin-Tin-Win-Shwe, Tha-Thu C.K., Moe Y., Fujitani Y., Tsukahara S., Hirano S.
    Name of Society : 11th International Particle Toxicology Conference (2016)
    Name of Proceedings : Abstract, 54
  • Evaluation of potentially developmentally neurotoxic chemicals using behavioral testing and neuroendocrinological analysis
    Presenter : Maekawa F., Sano K., Suzuki G., Nakayama S., Isobe T., Tin-Tin-Win-Shwe, Hashimoto S., Kawashima T.
    Name of Society : The 93rd Annual Meeting of the Physiological Society of Japan (2016)
    Name of Proceedings : Proceedings of The 93rd Annual Meeting of the Physiological Society of Japan, 66(supplement1):S73
  • Monitoring the Environmental Water Samples from South East Asia Countries: Vietnam River and Inle Lake, Myanmar using in vitro Bioassay
    Presenter : Nakajima D., Tin-Tin-Win-Shwe, Shiraishi F., Nguyen Thanh Thao, Nguyen Quang Trung, YAGISHITA M., Sone H., Kadokami K., Nay Soe Maung, Yoneda M.
    Name of Society : 44th Myanmar Health Research Congress, National Institute for Environmental Studies (NIES) and University of Public Heath (UPH) Joint Symposium on - Environmental pollutants and health risk- (our environment, our health) (2016)
    Name of Proceedings : Abstracts
  • Effects of Developmental Arsenic Exposure on Social Behavior and Neuronal Morphology in Mice
    Presenter : Tin-Tin-Win-Shwe, Aung K.H., Tsukahara S., Nohara K.
    Name of Society : NIES Arsenic Workshop 2013 (2013)
    Name of Proceedings : Abstracts, 22
  • Expression of neuroimmune biomarkers in hypothalamus of allergic mice after early phthalate exposure
    Presenter : Tin-Tin-Win-Shwe, Yanagisawa R., Koike E., Nakajima D., Takano H., Nitta H.
    Name of Society : Annual Meeding of Society of Indoor Environment Japan 2012 (2012)
    Name of Proceedings : Abstracts, 118-119
  • Effect of exposure to intermediate frequency magnetic fields on memory function- related gene expression in hippocampus of C57BLmice.
    Presenter : Tin-Tin-Win-Shwe, OHTANI S, USHIYAMA A., Fujimaki H., Nitta H., KUNUGITA N.
    Name of Society : NEUROSCIENCE2012 (2012)
    Name of Proceedings : SOCIETY FOR NEUROSCIENCE MONDAY PROGRAM, 37
  • Spatial and non-spatial learning performance in mice exposed to nanoparticle-rich diesel exhaust particles
    Presenter : Tin-Tin-Win-Shwe, Kurokawa Y., Fujitani Y., Hirano S., Fujimaki H.
    Name of Society : The 52nd Annual Meeting of Japan Society for Atmospheric Environment (2011)
    Name of Proceedings : Abstracts of The 52nd Annual Meeting of Japan Society for Atmospheric Environment, 293
  • Targeting in nanoparticle-induced neurotoxicity in mice
    Presenter : Tin-Tin-Win-Shwe, Yamamoto S., Fujitani Y., Hirano S., Fujimaki H.
    Name of Society : 79th Annu.Meet.Jpn.Soc.Hygiene(第79回日本衛生学会学術総会) (2009)
    Name of Proceedings : Jpn.J.Hyg.(日衛誌), 64(2):291
  • Modulation of T cell development by biological and chemical agents neonatal mice
    Presenter : Fujimaki H., Tin-Tin-Win-Shwe, Yamamoto S.
    Name of Society : 7th Annu.Eur.Life Sci.Org.Meet. (2008)
    Name of Proceedings : Abstracts, 126
  • Analysis of toluene-induced extracellular amino acid neurotransmitter levels in the hippocampus using in vivo microdialysis in a freely moving mouse model
    Presenter : , NAKAJIMA Daisuke, Tin-Tin-Win-Shwe
    Name of Society : 11th Int.Congr.Toxicol.(Poster Session) (2007)
    Name of Proceedings : Abstracts(CD-R)
  • Immunomodulatory role of low-level toluene exposure in mice
    Presenter : , NAKAJIMA Daisuke, Tin-Tin-Win-Shwe
    Name of Society : 11th Int.Congr.Toxicol.(Poster Session) (2007)
    Name of Proceedings : Abstracts(CD-R)
  • Effects of nano rich-desel exhaust on lung inflammation related to cell wall components of gram positive bacteria in mice
    Presenter : Yamamoto S., Takeuchi S.(*1), Fujitani Y., Fukushima A., Tin-Tin-Win-Shwe, Fujimaki H.
    Name of Society : 13th Int.Congr.Mucosal Immunol.(Poster Session) (2007)
    Name of Proceedings : Abstracts
  • Neuronal synaptic plasticity related gene expressions in the hippocampus and olfactory bulb of mice chronically exposed to low-level toluene
    Presenter : , Tin-Tin-Win-Shwe
    Name of Society : Int.Congr.Toxicol.(Poster Session) (2007)
    Name of Proceedings : Abstracts (CD-R)
  • Expression of transcription factor genes for T-cell differentiation in the spleen of C3H/HeN and BALB/c mice by the inhalation of low-level toluene
    Presenter : Fukushima A., Tin-Tin-Win-Shwe, Yamamoto S., Kunugita N.(*1), Yoshida Y.(*1), Arashidani K.(*1), Fujimaki H.
    Name of Society : World Allergy Congr.2007(Poster Session) (2007)
    Name of Proceedings : Abstracts
  • Effect of prenatal and postnatal exposure to low-level toluene and peptidoglycan on systematic Th1/Th2 immunity in infant mice
    Presenter : Yamamoto S., Fukushima A., Tin-Tin-Win-Shwe, Hojo R., Yoshida Y.(*1), Kunugita N.(*1), Arashidani K.(*1), Fujimaki H.
    Name of Society : World Allergy Congr.2007(Poster Session) (2007)
    Name of Proceedings : Abstracts
  • T cell-mediated neuroprotective response in toxic chemical induced memory-related gene expressions in a mouse hippocampus
    Presenter : , NAKAJIMA Daisuke, Tin-Tin-Win-Shwe
    Name of Society : 23rd Int.Neurotoxicol.Conf.(Poster Session) (2006)
    Name of Proceedings : Abstracts
  • Effects of low-level formaldehyde exposure on apoptosis-related molecules in the hippocampus of mice
    Presenter : , Tin-Tin-Win-Shwe
    Name of Society : 23th Int.Neurotoxicol.Conf.(Poster Session) (2006)
    Name of Proceedings : Abstracts
  • Role of CD4 T cells in allergic inflammatory responses in mice exposed to low-level toluene
    Presenter : NAKAJIMA Daisuke, Tin-Tin-Win-Shwe
    Name of Society : 1st Jt.Meet.Eur.Natl.Soc.Immunol. (2006)
    Name of Proceedings : Abstracts
  • Effect of ultrafine carbon particles on peptidoglycan-induced early pulmonary inflammation in mice
    Presenter : Yamamoto S., Ahmed S., Tin-Tin-Win-Shwe, Fujimaki H.
    Name of Society : 1st Jt.Meet.Eur.Natl.Soc.Immunol.(Poster Session) (2006)
    Name of Proceedings : Abstracts
  • Modulated memory-related gene expression in olfactory bulb of low-level toluene-exposed mice
    Presenter : , NAKAJIMA Daisuke, Tin-Tin-Win-Shwe
    Name of Society : 5th Forum Eur.Neurosci.(Poster Session) (2006)
    Name of Proceedings : Abstracts, 3
  • Modulated CXCL12 production in mice exposed to low level toluene
    Presenter : , NAKAJIMA Daisuke, Tin-Tin-Win-Shwe
    Name of Society : Int.Cytokine Soc.Conf.2005(Poster Session) (2006)
    Name of Proceedings : Abstracts
  • Modulation of pro-inflammatory and neural activity-related gene expression in the olfactory bulb of mice by nasal inhalation of low-level toluene
    Presenter : , KUROKAWA Yoshika, NAKAJIMA Daisuke, Tin-Tin-Win-Shwe
    Name of Society : 8th Int.Congr.Neuroimmunol.(ISNI 2006)(Poster Session) (2006)
    Name of Proceedings : J.Neuroimmunol., 178(S1)
  • Role of T cells in toluene-induced memory-related gene expressions in mouse hippocampus
    Presenter : , NAKAJIMA Daisuke, Tin-Tin-Win-Shwe
    Name of Society : 8th Int.Congr.Neuroimmunol.(ISNI 2006) (2006)
    Name of Proceedings : J.Neuroimmunol.
  • Synergistic effect of ultrafine carbon particles and staphylococcal cell wall components on early pulmonary inflammation
    Presenter : Yamamoto S., Tin-Tin-Win-Shwe, Fujimaki H.
    Name of Society : 3rd World Congr.Immunopathol.Respir.Allergy (2005)
    Name of Proceedings : Abstracts, 7(1)
  • Brain cytokine and chemokine mRNA expressions in mice intranasally instilled with ultrafine carbon black
    Presenter : Tin-Tin-Win-Shwe, Yamamoto S., Fujimaki H.
    Name of Society : 3rd World Congr.Immunopathol.Respir.Allergy (2005)
    Name of Proceedings : Abstracts, 7(1)
  • Suppression of IFN-gamma production in mice exposed to low level toluene
    Presenter : , NAKAJIMA Daisuke, Tin-Tin-Win-Shwe
    Name of Society : 3rd World Congr.Immunopathol.Respir.Allergy (2005)
    Name of Proceedings : Abstracts, 7(1)
  • Effect of ultrafine carbon particles on lipoteichoic acid-induced early pulmonary inflammation in mice
    Presenter : Yamamoto S., Tin-Tin-Win-Shwe, Ahmed S.,
    Name of Society : Int.Cytokine Soc.Conf.2005(Poster Session) (2005)
    Name of Proceedings : Abstracts
  • Role of lymphocytes in toluene-induced chemokine mRNA expression in mouse olfactory bulb
    Presenter : , NAKAJIMA Daisuke, Tin-Tin-Win-Shwe
    Name of Society : Int.Cytokine Soc.Conf.2005(Poster Session) (2005)
    Name of Proceedings : Abstracts
  • Effects of exposure to bisphenol A on memory function and neuroimmune biomarkers in allergic asthmatic mice
    Presenter : Tin-Tin-Win-Shwe, Yanagisawa R., Koike E., Takano H
    Name of Society : 24th Annual Meeting of the Japanese Society of Immunotoxicology (2017)
    Name of Proceedings : Abstracts, 84
  • Developmental exposure to tetrabromobisphenol A (TBBPA) on late onset behavior and neurological biomarkers in adult mice
    Presenter : Tin-Tin-Win-Shwe, Sano K., Isobe T., Kawashima T., Suzuki G., Hashimoto S., Nakayama S., Maekawa F.
    Name of Society : The 40th Annual Meeting of the Japan Neuroscience Society (2017)
    Name of Proceedings : Abstract, 218
  • Adolescent Exposure to Intermediate-Frequency Magnetic Fields Affects Neurological and Immunological Biomarkers in Young Adult Male Mice
    Presenter : Tin-Tin-Win-Shwe, Ohtani S., Kunugita N., Ushiyama A.
    Name of Society : 45th Myanmar Health Research Congress (2017)
    Name of Proceedings : Abstract, 93
  • Social behavior and related gene expressions in fragile X mental retardation 1 (Fmr1) gene knockout and valproic acid (VPA)-induced autism rat models
    Presenter : Tin-Tin-Win-Shwe, Watanabe H.
    Name of Society : 45th Myanmar Health Research Congress (2017)
    Name of Proceedings : Abstract, 88-89
  • Effects of perinatal exposure to a phosphate ester flame retardant on novel object recognition ability and memory function-related gene expression in adult mice
    Presenter : Tin-Tin-Win-Shwe, Sano K., Isobe T., Kawashima T., Suzuki G., Hashimoto S., Nakayama S., Maekawa F.
    Name of Society : 45th Myanmar Health Research Congress (2017)
    Name of Proceedings : Abstract, 120
  • Comprehensive analysis of house dust using GC×GC-HRTOFMS and in-house software
    Presenter : Ieda T., Hashimoto S., Takazawa Y., Tanabe K., Zushi Y., Shibata Y., Maekawa F., Sano K., Suzuki G., Nakayama S., Isobe T., Tin-Tin-Win-Shwe, Kawashima T.
    Name of Society : DIOXIN2016 (2016)
    Name of Proceedings : Abstracts
  • Lactational exposure to benzo[a]pyrene (BaP) on neuroimmune biomarkers in hippocampus of an allergic asthmatic mouse model
    Presenter : Tin-Tin-Win-Shwe, Htike N.T.T., Tsukahara S., Koike E., Yanagisawa R.
    Name of Society : The 39th Annual Meeting of the Japan neuroscience Society (2016)
    Name of Proceedings : Abstract, 189
  • Presenter : Sano K., Yang J., Tin-Tin-Win-Shwe, Maekawa F.
    Name of Society : 10th FENS (the Federation of European Neuroscience Societies) Forum (2016)
    Name of Proceedings : Abstracts, (C076)
  • Perinatal exposure to a phosphate ester flame retardant affects memory function and related gene expression in adult mice
    Presenter : Tin-Tin-Win-Shwe, Sano K., Isobe T., Kawashima T., Suzuki G., Hashimoto S., Nakayama S., Maekawa F.
    Name of Society : The 5th Annual Meeting of The Japan Society for Developmental Origins of Health and Disease (DOHaD-Japan) (2016)
    Name of Proceedings : Abstract(P-07), 40
  • Role of toll-like receptor 4 in diesel exhaust origin secondary organic aerosol-induced impaired spatial learning ability in neonatal mice
    Presenter : Tin-Tin-Win-Shwe, Fujitani Y., Watanabe H., Hirano S.
    Name of Society : Society for Neuroscience 2016 (2016)
    Name of Proceedings : Abstract, 61
  • Novel approach to olfactory-based spatial learning ability for preweaning mice and the effects of early exposure to diesel exhaust origin secondary organic aerosol
    Presenter : Tin-Tin-Win-Shwe, Chaw Kyi Tha Thu, Yadanar Moe, Fujitani Y., Shinji Tsukahara, Maekawa F., Hirano S.
    Name of Society : 44th Myanmar Health Research Congress (2016)
    Name of Proceedings : Abstract, 79
  • Presenter : Tin-Tin-Win-Shwe, Chaw Kyi-Tha Thu, Yadanar Moe, Fujitani Y., Shinji Tsukahara, Nitta H., Hirano S.
    Name of Society : 51st Congress of the European Societies of Toxicology (2015)
    Name of Proceedings : Abstract, 120
  • Presenter : Kurokawa Y., Zeng Y., Tin-Tin-Win-Shwe, Kimura H, Koyama Y, Matsui Y, Hirano S., Sone H.
    Name of Society : 第38回日本神経科学大会(The 38th Annual Meeting of the Japan Neuroscience Society) (2015)
    Name of Proceedings : Abstracts
  • Developmental exposure to diesel engine exhaust origin secondary organic aerosol on social behavior in adult mice
    Presenter : Tin-Tin-Win-Shwe, Chaw Kyi Tha Thu, Yadanar Moe, Fujitani Y., Tsukahara S, Watanabe H., Hirano S.
    Name of Society : 8th Federation of the Asian and Oceanian Physiological Society Congress (2015)
    Name of Proceedings : Abstracts, S-A178
  • Effect of developmental exposure to acetamiprid on behavioral profiles in mice
    Presenter : Sano K., Yang J., Tin-Tin-Win-Shwe, Nohara K., Maekawa F.
    Name of Society : The 8th congress of the federation of the asian and oceanian physiological societies (2015)
    Name of Proceedings : Abstracts, 65(Supplemental 2):S-A179
  • Presenter : Kurokawa Y., Zeng Y., Zeng Q, Tin-Tin-Win-Shwe, Hirano S., Sone H.
    Name of Society : 37th Annual Meeting of the Japan Neuroscience Society (2014)
    Name of Proceedings : -
  • Effects of developmental exposure to diesel engine exhaust origin secondary organic aerosol on social and learning behavior in adult mice
    Presenter : Tin-Tin-Win-Shwe, Maekawa F., Chaw Kyi Tha Thu, Fujitani Y., Yanagisawa R., Furuyama A., Tsukahara S, Nohara K., Nitta H., Hirano S.
    Name of Society : 37th Annual Meeting of the Japan Neuroscience Society (2014)
    Name of Proceedings : Abstract, 131
  • Presenter : Tin-Tin-Win-Shwe, Fujitani Y., Chaw Kyi ThaThu, Furuyama A., Shinji Tsukahara, Nitta H., Hirano S.
    Name of Society : 8th International Congress of Neuroendocrinology 2014 (2014)
    Name of Proceedings : Abstract, 31
  • Presenter : Tin-Tin-Win-Shwe, Yanagisawa R., Koike E., Nitta H., Takano H.
    Name of Society : International Conference of Asian Environmental Chemistry 2014 (2014)
    Name of Proceedings : Abstract, 318
  • Presenter : Tin-Tin-Win-Shwe, Ohtani S., Ushiyama A., Kunugita N.
    Name of Society : International Conference of Asian Environmental Chemistry 2014 (2014)
    Name of Proceedings : Abstract, 325
  • Impact of hexabromocyclododecane on lipid and glucose metabolism in high-fat diet-induced obese mice
    Presenter : YANAGISAWA Rie, TIN-TIN-Win-Shwe, KOIKE Eiko
    Name of Society : 49th Congress of the European Societies of Toxicology (2013)
    Name of Proceedings : Abstracts o the 49th Congress of the European Societies of Toxicology (EUROTOX), 221S:S252-S252
  • Biodistribution and toxicological effects of intranasally instilled polyamidoamine(PAMAM)dendrimers in BALB/c mouse brain
    Presenter : Tin-Tin-Win-Shwe, Kurokawa Y., Nitta H., Hirano S., Sone H.
    Name of Society : eurotox 2013 (2013)
    Name of Proceedings : Toxicology Letters, 221S(28):S240
  • Presenter : Zeng Y., Tin-Tin-Win-Shwe, Kurokawa Y., ZHANG Z., Sone H.
    Name of Society : 環境ホルモン学会第16回研究発表会 (2013)
    Name of Proceedings : なし
  • Effects of PAMAM dendrimer exposures during neuronal differentiation from human neural progenitor cells
    Presenter : Zeng Y., Tin-Tin-Win-Shwe, Kurokawa Y., ZHANG.Z.Y., Sone H.
    Name of Society : 細胞アッセイ技術の現状と将来 (2013)
    Name of Proceedings : -
  • Intracellular distribution of PAMAM dendrimers in cultured human cells
    Presenter : Kurokawa Y., Tin-Tin-Win-Shwe, Zeng Q, Hirano S., Sone H.
    Name of Society : 6th International Symposium on Nanotechnology, Occupational and Environmental Health (NanOEH) (2013)
    Name of Proceedings : Abstracts, 89
  • In vivo and in vitro biological effects and biodistribution of PAMAM-NH2 dendrimers
    Presenter : Tin-Tin-Win-Shwe, Kurokawa Y., Zeng Y., Nitta H., Hirano S., Sone H.
    Name of Society : 6th International Symposium on Nanotechnology,Occupational and Environmental Health (2013)
    Name of Proceedings : Abstracts, 31
  • Determinations of PAMAM particles in culture media using SPM techniques
    Presenter : Sone H., Yamazaki M., Zaha H., Zeng Y., Kurokawa Y., Tin-Tin-Win-Shwe, Hirano S.
    Name of Society : 6th International Symposium on Nanotechnology, Occupational and Environmental Health (NanOEH) (2013)
    Name of Proceedings : -
  • Effect of PAMAM dendrimers on differentiation of hNPCs: A study of morphological analysis
    Presenter : Zeng Y., Tin-Tin-Win-Shwe, Zeng Q, Kurokawa Y., Hirano S., ZHANG.A.Y, Sone H.
    Name of Society : 6th International Symposium on Nanotechnology,Occupational and Environmental Health (2013)
    Name of Proceedings : Abstracts
  • Hippocampus-dependent spatial learning deficit in mice following sub-chronic exposure to nanoparticle-rich diesel exhaust
    Presenter : Tin-Tin-Win-Shwe, Fujitani Y., Hirano S., Fujimaki H.
    Name of Society : Eurotox2011 PARIS (2011)
    Name of Proceedings : Program of Eurotox2011 PARIS, 124
  • Developmental diazinon exposure induces immune dysfunction in adult mice
    Presenter : Fujimaki H., Tin-Tin-Win-Shwe
    Name of Society : Eurotox2011 PARIS (2011)
    Name of Proceedings : Program of Eurotox2011 PARIS, 131
  • Impact of toll-like receptor(TLR)4 on hippocampus-dependent object recognition in early life diazinon exposure
    Presenter : Tin-Tin-Win-Shwe, Fujimaki H.
    Name of Society : Neuroscience 2011 (2011)
    Name of Proceedings : Society for Neuroscience Program, 72
  • Toll-like receptor 4-dependent neurotrophin signaling in mouse hippocampus following low-level toluene exposure
    Presenter : Tin-Tin-Win-Shwe, Kunugita N., Yoshida Y., Arashidani K., Fujimaki H.
    Name of Society : 14th Int.Congr.Immunol. (2010)
    Name of Proceedings : Abstracts, 22S(1):i87
  • Role of TLR4 signaling pathway in neurotrophin gene expression in mice lungs following low-level toluene exposure
    Presenter : Fujimaki H., Tin-Tin-Win-Shwe, Yoshida Y., Kunugita N., Arashidani K.
    Name of Society : 14th Int.Congr.Immunol. (2010)
    Name of Proceedings : Abstracts, 22S(1):ii136
  • Toll-like receptor 4-dependent upregulation of heme oxygenase-1 and anti-inflammatory cytokines in mouse lung following low-level toluene exposure
    Presenter : Fujimaki H., Tin-Tin-Win-Shwe, Yoshida Y., Kunugita N., Arashidani K.
    Name of Society : 12th Int.Congr.Toxicol. (2010)
    Name of Proceedings : Toxicol.Lett., 196S:S193
  • Developmental toluene exposure alters neuroimmune markers in the hippocampus of infant mice
    Presenter : Tin-Tin-Win-Shwe, Kunugita N., Yoshida Y., Arashidani K., Fujimaki H.
    Name of Society : 12th Int.Congr.Toxicol. (2010)
    Name of Proceedings : Toxicol.Lett., 196S:S194
  • Modulation of the expression of transcription factors mRNAs in spleen from the mice following organophosphate pesticide exposure
    Presenter : Fujimaki H., Tin-Tin-Win-Shwe
    Name of Society : 8th Asia Pac.Congr.Allergy, Asthma Clin.Immunol. (2010)
    Name of Proceedings : Program & Abstracts , 114
  • Toll-like receptor 4 mediated neurotrophins, their receptors and signaling pathways in the neuroinflammation of organophosphate pesticides
    Presenter : Tin-Tin-Win-Shwe, Fujimaki H.
    Name of Society : 8th Asia Pac.Congr.Allergy, Asthma Clin.Immunol. (2010)
    Name of Proceedings : Program & Abstracts , 114
  • Effect of perinatal toluene exposure at different developmental phases on memory function-related gene expressions in mouse brain
    Presenter : Tin-Tin-Win-Shwe, Kunugita N., Yamamoto S., Arashidani K., Fujimaki H.
    Name of Society : 50th Annu.Meet.Jpn.Soc.Atmos.Environ. (2009)
    Name of Proceedings : Abstracts, 342
  • Strain differences influence synaptic plasticity-related gene expression in olfactory bulb of a mouse model of allergy following toluene exposure
    Presenter : Fujimaki H., Tin-Tin-Win-Shwe, Kunugita N., Yamamoto S., Arashidani K.
    Name of Society : 13th Congr.Eur.Fed.Neurol.Soc. (2009)
    Name of Proceedings : Abstracts, 566
  • Analysis of neurotoxic effect of nanoparticle-rich diesel exhaust on a mouse brain
    Presenter : Yamamoto S., Tin-Tin-Win-Shwe, Mitsushima D., Fujitani Y., Hirano S., Fujimaki H.
    Name of Society : 13th Congr.Eur.Fed.Neurol.Soc. (2009)
    Name of Proceedings : Abstracts, 325
  • A potential role of hippocampal memory function-related gene expression in developmental neurotoxicity of toluene
    Presenter : Tin-Tin-Win-Shwe, Kunugita N., Yamamoto S., Arashidani K., Fujimaki H.
    Name of Society : 13th Congr.Eur.Fed.Neurol.Soc. (2009)
    Name of Proceedings : Abstracts, 324
  • Effects of toluene exposure on developmental immunotoxicity in infant mice brain
    Presenter : Tin-Tin-Win-Shwe, Kunugita N., Yamamoto S., Arashidani K., Fujimaki H.
    Name of Society : 16th Annu.Meet.Jpn.Soc.Immunotoxicol. (2009)
    Name of Proceedings : Abstracts, 76
  • Presenter : Tin-Tin-Win-Shwe, Yamamoto S., Fujitani Y., Hirano S., Fujimaki H.
    Name of Society : 31st Annu.Meet.Jpn.Neurosci.Soc. (2008)
    Name of Proceedings : Neurosci.Res., 61(Suppl.1):S258
  • Neurotoxic effect of nanoparticle-rich diesel exhaust in the mouse olfactory bulb
    Presenter : Tin-Tin-Win-Shwe, Mitsushima D., Yamamoto S., Fujitani Y., Funabashi T., Hirano S., Fujimaki H.
    Name of Society : 45th Congr.Eur.Soc.Toxicol. (2008)
    Name of Proceedings : Toxicol.Lett., 180S(2008):S206
  • In vivo evaluation of a flame retardant having estrogenic activity using mouse model
    Presenter : Sano K., Suzuki G., Htike N.T.T., Morishita M., Tin-Tin-Win-Shwe, Hashimoto S., Kawashima T., Isobe T., Nakayama S., Tsukahara S., Maekawa F.
    Name of Society : Application of Recent Advances in Neuroscience to Environmental Health Research (2016)
    Name of Proceedings : abstract, 1-4
  • Studies on the effects of toluene exposure on developing immune system
    Presenter : Tin-Tin-Win-Shwe, Kunugita N., Yoshida Y., Fujimaki H.
    Name of Society : 第18回日本免疫毒性学会学術大会 (2011)
    Name of Proceedings : 第18回日本免疫毒性学会学術大会講演要旨集, 64