Latest Update:2017/12/06 19:20:57

UMEZU Toyoshi

UMEZU Toyoshi
Researcher Name
UMEZU Toyoshi
Div (Section) name/title
Center for Health and Environmental Risk Research(Health Effect Assessment Section)/Head
Research Subject
Studies on effects of chemicals on Central Nervous system
Degree(s)
Ph.D
Professional Qualification(s)
Medicine,Pharmacy,Physiology
Environmental Speciality Field
risk assessment,hazardous chemical substances,Aroma Environment
Keyword(s)
Behavioral sciences,Neurochemistry,Neurotoxicity,Neuropyschiatric disorders,Developmental diseases,Neuropharmacology,Aromatherapy,smell/fragrance
Brief Description of Research
Since we humans are exposed to various kinds of environmental chemicals, their safety have been concerned. Health risk assessment on various chemicals have been proceeded, however, shortage of information on neurotoxicity of chemicals is remarkable, thus their impact have hardly been elucidated. I am working on development of new methods and arrangement of test batteries for evaluating neurotoxicity and application of them to various chemicals to provide neurotoxicity data of various environmental chemicals. My special interest is on development and application of new behavioral methods and test batteries for evaluating neurotoxicity of environmental chemicals and providing neurotoxicity data using those methods. I am also interested in good effects of environmental chemicals on mental function, and working on neuropharmacological effects of aromatic and/or odor chemicals.
Career
1980~1984 College of Biological Sciences, Second Cluster of College, University of Tsukuba
1984~1986 Graduate School of Environmental Sciences, University of Tsukuba
1986~1990 Graduate School of Medicine, Gunnma University
1990~ National Institute for Environmental Studies
1995~1997 University of Virginia (Visiting Researcher)
URL
http://www.nies.go.jp/gaiyo/bunya/chem-e.html
Membership of Academic Society
Japanese Pharmacological Society (JPS),The pharmaceutical society of japan,Japanese Society of Neuropsychopharmacology,Japan Society of Endocrine Disrupters Research (JSEDR),Japanese Society for Chronobiology,Japanese Society of Behavioral Medicine
Research Subject
  • Fiscal Year: 2017
    • 23824 : Research project on health impacts of chemicals on children and future generations
    • 23847 : Research program on health and environmental safety
    • 23975 : A fundamental study for evaluating health impact of environmental factors
    • 23976 : A study on psychoactive effects of plant-derived substances for developing healthy aroma environment
  • Fiscal Year: 2016
    • 23414 : Research program on health and environmental safety
    • 23415 : Research project on health impacts of chemicals on children and future generations
    • 23598 : A study on psychoactive effects of plant-derived substances for developing healthy aroma environment
    • 23659 : A fundamental study for evaluating health impact of environmental factors
  • Fiscal Year: 2015
    • 23110 : A study on systematization of neurobehavioral methods for evaluating health effects of environmental chemicals
    • 23111 : A study on psychoactive effects of plant-derived substances for developing healthy aroma environment
  • Fiscal Year: 2014
    • 22880 : A study on systematization of neurobehavioral methods for evaluating health effects of environmental chemicals
    • 22884 : A study on psychoactive effects of plant-derived substances for developing healthy aroma environment
  • Fiscal Year: 2013
    • 22461 : A study on psychoactive effects of plant-derived substances for developing healthy aroma environment
    • 22462 : A study on systematization of neurobehavioral methods for evaluating health effects of environmental chemicals
  • Fiscal Year: 2012
    • 22031 : A study on psychoactive effects of plant-derived substances for developing healthy aroma environment
    • 22034 : A study on systematization of neurobehavioral methods for evaluating health effects of environmental chemicals
  • Fiscal Year: 2011
    • 21405 : Research for monitoring and risk assessment of cyanotoxin microcystin
    • 21556 : Neuropharmacological study for effects of nicotine and menthol on depression symptom
    • 21557 : A study on psychoactive effects of plant-derived substances for developing healthy aroma environment
    • 21564 : A study on systematization of neurobehavioral methods for evaluating health effects of environmental chemicals
  • Fiscal Year: 2010
    • 21071 : Study on establishment of behavioral tests system for evaluation of health effects of environmental chemicals
    • 21072 : Neuropharmacological study for effects of nicotine and menthol on depression symptom
    • 21073 : A study on psychoactive effects of plant-derived substances for developing healthy aroma environment
  • Fiscal Year: 2009
    • 20509 : Quantification of ferritin, an iron storage protein in vivo and its application to molecular imaging
    • 20632 : Study on establishment of behavioral tests system for evaluation of health effects of environmental chemicals
    • 20633 : Neuropharmacological study for effects of nicotine and menthol on depression symptom
    • 20634 : A study on psychoactive effects of plant-derived substances for developing healthy aroma environment
  • Fiscal Year: 2008
    • 20103 : Quantification of ferritin, an iron storage protein in vivo and its application to molecular imaging
    • 20225 : Study on establishment of behavioral tests system for evaluation of health effects of environmental chemicals
  • Fiscal Year: 2007
    • 10477 : Behavioral toxicological study for developmental effects of diphenylarsinic acid
    • 10605 : Study on establishment of behavioral tests system for evaluation of health effects of environmental chemicals
    • 10723 : Quantification of ferritin, an iron storage protein in vivo and its application to molecular imaging
  • Fiscal Year: 2006
    • 10081 : Study on the metabolism underlying brain function using an ultra high field multinuclear MRI system
    • 10221 : Behavioral toxicological study for developmental effects of diphenylarsinic acid
    • 10338 : Study on establishment of behavioral tests system for evaluation of health effects of environmental chemicals
  • Fiscal Year: 2005
    • 9337 : MRI, behavioral and neurochemical study on the effect of endocrine disrupting chemicals on the nervous system.
    • 9341 : Study on the effect of endocrine disrupting chemicals to the reproductive and immune system.
    • 9388 : Study on establishment of behavioral tests system for evaluation of health effects of environmental chemicals
    • 9554 : Study on the metabolism underlying brain function using an ultra high field multinuclear MRI system
  • Fiscal Year: 2004
    • 8972 : MRI, behavioral and neurochemical study on the effect of endocrine disrupting chemicals on the nervous system.
    • 8976 : Study on the effect of endocrine disrupting chemicals to the reproductive and immune system.
    • 9022 : Study on establishment of behavioral tests system for evaluation of health effects of environmental chemicals
    • 9305 : Study on the metabolism underlying brain function using an ultra high field multinuclear MRI system
  • Fiscal Year: 2003
    • 8675 : Development of ultrahighfieldmultinuclear MRI system for human measurements
    • 8689 : MRI, behavioral and neurochemical study on the effect of endocrine disrupting chemicals on the nervous system.
    • 8693 : Study on the effect of endocrine disrupting chemicals to the reproductive and immune system.
    • 8740 : Study on establishment of behavioral tests system for evaluation of health effects of environmental chemicals
  • Fiscal Year: 2002
    • 8459 : Development of ultra high field multinuclear MRI system for human measurements
    • 8474 : MRI, behavioral and neurochemical study on the effect of endocrine disrupting chemicals on the nervous system.
    • 8522 : Study on establishment of behavioral tests system for evaluation of health effects of environmental chemicals
    • 8538 : Study on the effect of endocrine disrupting chemicals to the reproductive and immune system.
  • Fiscal Year: 2001
    • 8236 : Development of ultra high field multinuclear MRI system for human measurements
    • 8252 : MRI, behavioral and neurochemical study on the effect of endocrine disrupting chemicals on the nervous system.
    • 8284 : Study on establishment of behavioral tests system for evaluation of health effects of environmental chemicals
Research Result (Publication)
  • all
  • Original Paper
Research Result (Presentation)
  • all
  • Research Presentation
  • Research Presentation
    Rapid transport of diphenylarsinic acid into brain through blood-brain barrier as revealed by microdialysis combined with LCMSMS
    Presenter : Shibata Y., Umezu T., Hosoya T., Takagi M. , Nakamiya K.
    Name of Society : Metallomics 2013 (2013)
    Name of Proceedings : Abstracts
  • Research Presentation
    Behavioral pharmacology of plant-derived substances(15): Effects of mentol on extracellular dopamine,serotonine,norepinephrine and their metabolites in mouse striatum.Comparison with effects of bupropion,methylphenidate and cffeine
    Presenter : UMEZU Toyoshi
    Name of Society : 79th Annu.Meet.Jpn.Pharmacol.Soc. (2006)
    Name of Proceedings : Abstracts
  • Research Presentation
    Behavioral pharmacology of plant-derived subustances(14): Interaction between menthol and nicotine on ambulation in mice
    Presenter : Umezu T., Morita M.
    Name of Society : 78th Annu.Meet.Jpn.Pharm.Soc. (2005)
    Name of Proceedings : J.Pharm.Sci., 97(Suppl.1)
  • Research Presentation
    Behaviral pharmacology of plant-derived substances (13): anticonflict effects of lavender oil and identification of its active constituent
    Presenter : Umezu T., Ito H., Morita M.
    Name of Society : 24th CINP Congr.2004 (2004)
    Name of Proceedings : Abstracts, 7(Suppl.1)
  • Research Presentation
    Behavioral pharmacology of plant-derived substances(10)-behavioral effects of 2-phenethyl alcohol and citronellol in mice.Comparison with diazepam
    Presenter : Umezu T., Sato C.(*1), Yamada M.(*1), Sakaniwa M.(*1), Morita M.
    Name of Society : 76th Annu.Meet.Jpn.Pharmacol.Soc. (2003)
    Name of Proceedings : J.Pharmacol.Sci., 91(Suppl.1)(Suppl.1):91
  • Behavioral pharmacology of plant-derived substances(8): effects of plant-derived essential oils on the discrete shuttle type avoidance response in mice
    Presenter : Umezu T.
    Name of Society : 75th Annu.Meet.Jpn.Pharmocol.Soc. (2002)
    Name of Proceedings : Jpn.J.Pharmacol., 88(Suppl.1)
  • Rapid transport of diphenylarsinic acid into brain through blood-brain barrier as revealed by microdialysis combined with LCMSMS
    Presenter : Shibata Y., Umezu T., Hosoya T., Takagi M. , Nakamiya K.
    Name of Society : Metallomics 2013 (2013)
    Name of Proceedings : Abstracts
  • Behavioral pharmacology of plant-derived substances(15): Effects of mentol on extracellular dopamine,serotonine,norepinephrine and their metabolites in mouse striatum.Comparison with effects of bupropion,methylphenidate and cffeine
    Presenter : UMEZU Toyoshi
    Name of Society : 79th Annu.Meet.Jpn.Pharmacol.Soc. (2006)
    Name of Proceedings : Abstracts
  • Behavioral pharmacology of plant-derived subustances(14): Interaction between menthol and nicotine on ambulation in mice
    Presenter : Umezu T., Morita M.
    Name of Society : 78th Annu.Meet.Jpn.Pharm.Soc. (2005)
    Name of Proceedings : J.Pharm.Sci., 97(Suppl.1)
  • Behaviral pharmacology of plant-derived substances (13): anticonflict effects of lavender oil and identification of its active constituent
    Presenter : Umezu T., Ito H., Morita M.
    Name of Society : 24th CINP Congr.2004 (2004)
    Name of Proceedings : Abstracts, 7(Suppl.1)
  • Behavioral pharmacology of plant-derived substances(10)-behavioral effects of 2-phenethyl alcohol and citronellol in mice.Comparison with diazepam
    Presenter : Umezu T., Sato C.(*1), Yamada M.(*1), Sakaniwa M.(*1), Morita M.
    Name of Society : 76th Annu.Meet.Jpn.Pharmacol.Soc. (2003)
    Name of Proceedings : J.Pharmacol.Sci., 91(Suppl.1)(Suppl.1):91