Latest Update：2020/08/20 14:33:51

HIRANO Seishiro

Researcher Name: HIRANO Seishiro

Div (Section) name/title: Center for Health and Environmental Risk Research／Fellow

Research Subject: Toxicity of nanoparticles and nanomaterials
Metabolism and toxicity of metalloids

Degree(s): Ph.D. (Medical Science)

Professional Qualification(s): Medicine,Biochemistry,Chemistry

Environmental Speciality Field: toxicology

Research Subject

Fiscal Year: 2020
- 25099 : Research Program on Health and Environmental Safety
- 25146 : A study of Air Pollution Including PM2.5 and its Health and Toxic Effects
- 25172 : A basic study for health effects of cationic surfactants
- 25352 : Fundamental Study on the Basis of Health and Environmental Risk Research
Fiscal Year: 2019
- 24696 : Research Program on Health and Environmental Safety
- 24726 : A study of Air Pollution Including PM2.5 and its Health and Toxic Effects
- 24797 : A basic study for health effects of cationic surfactants
- 24977 : Fundamental Study on the Basis of Health and Environmental Risk Research
Fiscal Year: 2018
- 24309 : A study of air pollution including PM2.5 and its health and toxic effects
- 24311 : Research project on the scientific and social framework of risk assessment and management
- 24355 : Research program on health and environmental safety
- 24420 : A basic study for health effects of cationic surfactants
- 24553 : Fundamental study on the basis of health and environmental risk research
Fiscal Year: 2017
- 23817 : Research project on the scientific and social framework of risk assessment and management
- 23819 : A study of air pollution including PM2.5 and its health and toxic effects
- 23847 : Research program on health and environmental safety
- 24073 : Fundamental study on the basis of health and environmental risk research
Fiscal Year: 2016
- 23414 : Research program on health and environmental safety
- 23420 : A study of air pollution including PM2.5 and its health and toxic effects
- 23422 : Research project on the scientific and social framework of risk assessment and management
- 23449 : A mechanistic approach of arsenic toxicity using SUMOylation of Promyelocytic Leukemia protein as an indicator.
- 23507 : Atmospheric behavior and toxicity study of particulate matters from un-regulated burning
- 23659 : A fundamental study for evaluating health impact of environmental factors
- 23660 : A fundamental study on the integrated health risk evaluation.
Fiscal Year: 2015
- 23001 : Development of toxicity and safety evaluation methods for nanomaterials
- 23286 : Analysis of the effect of inorganic arsenite on reproductive function
- 23312 : Atmospheric behavior and toxicity study of particulate matters from un-regulated burning
- 23342 : Study on number and size distribution of particulate matter emitted from motor vehicle
Fiscal Year: 2014
- 22589 : Development of toxicity and safety evaluation methods for nanomaterials
- 22640 : Inflammasome activation and toxicity evaluation of nanofibers
- 22641 : Development of health risk evaluation methods for environmental toxicants on the basis of exposure routes.
- 22662 : A study of PM in urban atmosphere for reduction of PM and evaluation of toxicity and health impact of PM based on chemical compositions
- 22908 : Analysis of the effect of inorganic arsenite on reproductive function
- 22944 : Study on number and size distribution of particulate matter emitted from motor vehicle
- 22948 : Health effects of secondary organic aerosols derived from diesel exhaust.
Fiscal Year: 2013
- 22173 : Development of toxicity and safety evaluation methods for nanomaterials
- 22254 : A study of PM in urban atmosphere for reduction of PM and evaluation of toxicity and　health impact of PM based on chemical compositions
- 22256 : Characterization of arsenic-binding proteins and its application to toxicity evaluation.
- 22257 : Development of health risk evaluation methods for environmental toxicants on the basis of exposure routes.
- 22549 : Study on number and size distribution of particulate matter emitted from motor vehicle
- 22570 : Health effects of secondary organic aerosols derived from diesel exhaust.
Fiscal Year: 2012
- 21744 : Development of toxicity and safety evaluation methods for nanomaterials
- 21822 : A study of PM in urban atmosphere for reduction of PM and evaluation of toxicity and　health impact of PM based on chemical compositions
- 21917 : Characterization of arsenic-binding proteins and its application to toxicity evaluation.
- 21919 : Development of health risk evaluation methods for environmental toxicants on the basis of exposure routes.
- 22007 : Improvement of HEALS (Health Effects of Alert Systems) database
- 22126 : Study on number and size distribution of particulate matter emitted from motor vehicle
- 22149 : Health effects of secondary organic aerosols derived from diesel exhaust.
Fiscal Year: 2011
- 21301 : Development of toxicity and safety evaluation methods for nanomaterials
- 21388 : Characterization of arsenic-binding proteins and its application to toxicity evaluation.
- 21408 : Development of health risk evaluation methods for environmental toxicants on the basis of exposure routes.
- 21444 : Environmental Behavior and Toxicity of Secondary Organic Aerosols
- 21681 : Study on number and size distribution of particulate matter emitted from motor vehicle
- 21702 : Improvement of HEALS (Health Effects of Alert Systems) database
Fiscal Year: 2010
- 20852 : Long-term effects of organic arsenicals on the central nervous system.
- 20853 : Toxicodynamics and health effects of environemntal nanoparticles
- 20854 : Health effects of environmental nanoparticles in the automobile exhaust.
- 21050 : Environmental Behavior and Toxicity of Secondary Organic Aerosols
- 21247 : Study on number and size distribution of particulate matter emitted from motor vehicle
Fiscal Year: 2009
- 20458 : A study on metabolomics of metaloid
- 20459 : Development of aqeuous-chromatography sysytems to reduce environmental pollutant load.
- 20462 : Toxicodynamics and health effects of environemntal nanoparticles
- 20463 : Health effects of environmental nanoparticles in the automobile exhaust.
- 20607 : Environmental Behavior and Toxicity of Secondary Organic Aerosols
- 20691 : Study on number and size distribution of particulate matter emitted from motor vehicle
- 20809 : Long-term effects of organic arsenicals on the central nervous system.
Fiscal Year: 2008
- 20030 : Establishment of sensitive test methods to confirm thermal degradation of waste asbestos
- 20111 : A study on metabolomics of metaloid
- 20253 : Development of aqeuous-chromatography sysytems to reduce environmental pollutant load.
- 20255 : Toxicodynamics and health effects of environemntal nanoparticles
- 20256 : Health effects of environmental nanoparticles in the automobile exhaust.
Fiscal Year: 2007
- 10458 : A study on metabolomics of metaloid
- 10463 : Development of aqeuous-chromatography sysytems to reduce environmental pollutant load.
- 10541 : Establishment of sensitive test methods to confirm thermal degradation of waste asbestos
- 10584 : Toxicodynamics and health effects of environemntal nanoparticles
- 10628 : Health effects of environmental nanoparticles in the automobile exhaust.
Fiscal Year: 2006
- 10179 : A study on metabolomics of metaloid
- 10184 : Development of aqeuous-chromatography sysytems to reduce environmental pollutant load.
- 10199 : Redox and detoxication mechanism of arsenic in in vivo.
- 10279 : Establishment of sensitive test methods to confirm thermal degradation of waste asbestos
- 10317 : Toxicodynamics and health effects of environemntal nanoparticles
- 10362 : Health effects of environmental nanoparticles in the automobile exhaust.
Fiscal Year: 2005
- 9334 : Effects of particulate substances on the respiratory system
- 9471 : Study on health effects, characteristics and environmental behavior of nano- particles
- 9500 : DNA Methylation Changes May Be Useful As A Biomarker In Arsenic-Induced Health Effects？
- 9583 : A study on the uptake of nanoparticles by cells using AFM
- 9672 : A study on metabolomics of metaloid
- 9678 : Development of aqeuous-chromatography sysytems to reduce environmental pollutant load.
Fiscal Year: 2004
- 8959 : Effects of particulate substances on the respiratory system
- 9082 : Identification methods for genetic susceptibility to atmospheric toxic substances
- 9125 : Embryotoxicity screening of envrionmental pollutants using monkey embryonic stem cells.
- 9189 : Study on health effects, characteristics and environmental behavior of nano- particles
- 9224 : Proof of a novel metabolic pathway of arsenic.
- 9251 : DNA Methylation Changes May Be Useful As A Biomarker In Arsenic-Induced Health Effects？
Fiscal Year: 2003
- 8602 : Effects of phytoestrogens and endocrine disruptors on the bone metabolism.
- 8637 : Effects of particulate substances on the respiratory system
- 8802 : Identification methods for genetic susceptibility to atmospheric toxic substances
- 8872 : Embryotoxicity screening of envrionmental pollutants using monkey embryonic stem cells.
- 8919 : Study on health effects, characteristics and environmental behavior of nano- particles
Fiscal Year: 2002
- 8325 : Effects of phytoestrogens and endocrine disruptors on the bone metabolism.
- 8371 : Studies on the development of the methods to evaluate the health effects of particles
- 8402 : Effects of particulate substances on the respiratory system
Fiscal Year: 2001
- 8032 : Effects of phytoestrogens and endocrine disruptors on the bone metabolism.
- 8155 : Effects of particulate substances on the respiratory system

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Research Result (Publication)

all
Original Paper
Review
Book
Other Publications

Review
Biotransformation of arsenic and toxicological implication of arsenic metabolites

Presenter : Hirano S.
Title : , Archives of Toxicology, 94(8):2587-2601 (2020)
Original Paper
Cellular uptake of paraquat determines subsequent toxicity including mitochondrial damage in lung epithelial cells

Presenter : Kanno S., Hirano S., Mukai T., Ro A., Fukuta M., Aoki Y.
Title : , Legal Medicine, 37:7-14 (2019)
Original Paper
Influence of polymeric precursors on the viability of human cells of yttrium aluminum borates nanoparticles doped with ytterbium ions

Presenter : Cieslik I., Plocinska M., Plocinski T., Zdunek J., Wozniak M.J., Bil M., Hirano S.
Title : , Applied Surface Science, 488:874-886 (2019)
Original Paper
Effects of diesel exhaust derived secondary organic aerosol (DE-SOA) exposure during developmental period on anxiety and depression in mice

Presenter : Tin-Tin-Win-Shwe, Fujitani Y., Hirano S.
Title : , Indoor Environment, 22(1):23-32 (2019)
Original Paper
Effects of diesel exhaust-derived secondary organic aerosol (SOA) on oocytes: Potential risks to meiotic maturation

Presenter : Udagawa O., Furuyama A., Imai K., Fujitani Y., Hirano S.
Title : , Reproductive Toxicology, 75:56-64 (2018)
Original Paper
Nano-QSAR modeling for ecosafe design of heterogeneous TiO2-based nano-photocatalysts

Presenter : Mikolajczyk A., Gajewicz A., Mulkiewicz E., Rasulev B., Marchelek M., Diak M., Hirano S., Zaleska-Medynska A., Puzyn T.
Title : , Environmental Science Nano, 1 (2018)
Original Paper
Potassium gadolinium tungstate nanocrystals doped with holmium ions as candidates for optical imaging

Presenter : Cieślik I., Bolek T., Woźniak M.J., Majchrowski A., Hirano S.
Title : , Applied Surface Science, 446:139-144 (2018)
Original Paper
Solubility changes of promyelocytic leukemia (PML) and SUMO monomers and dynamics of PML nuclear body proteins in arsenite-treated cells

Presenter : Hirano S., Udagawa O., Kobayashi Y., Kato A.
Title : , Toxicology and Applied Pharmacology, 360:150-159 (2018)
Original Paper
Characterization and influence of hydroxyapatite nanopowders on living cells

Presenter : Oberbek P., Bolek T., Chlanda A., Hirano S., Kusnieruk S., Rogowska-Tylman J., Nechyporenko G., Zinchenko V., Swieszkowski W., Puzyn P.
Title : , Beilstein Journal of Nanotechnology, 9:3079-3094 (2018)
Original Paper
Pharmacodynamics of S-dimethylarsino-glutathione, a putative metabolic intermediate of inorganic arsenic, in mice

Presenter : Kato A., Kobayashi Y., Udagawa O., Hirano S.
Title : , Biochemical Pharmacology, 126:79-86 (2017)
Original Paper
Oxidative stress and cytotoxic effects of silver ion in mouse lung macrophages J774.1 cells

Presenter : Ilseob Shim, Kyunghee Choi, Hirano S.
Title : , Journal of Applied Toxicology, 37:471-478 (2017)
Original Paper
Comparison of Oxidative Abilities of PM2.5 Collected at Traffic and Residential Sites in Japan. Contribution of Transition Metals and Primary and Secondary Aerosols

Presenter : Fujitani Y., Furuyama A., Tanabe K., Hirano S.
Title : , Aerosol and Air Quality Research, 17:574-587 (2017)
Original Paper
Neurotoxicity Assessment of Secondary Organic Aerosol by Intranasal and Inhalation Exposure in Mice

Presenter : Tin-Tin-Win-Shwe, Fujitani Y., Hirano S.
Title : , Earozoru Kenkyu, 32(3):169-175 (2017)
Original Paper
Differential Regulation of IL-1β and IL-6 Release in Murine Macrophages

Presenter : Hirano S., Zhou Q., Furuyama A., Kanno S.
Title : , Inflammation, 40(6):1933-1943 (2017)
Original Paper
Role of TLR4 in olfactory-based spatial learning activity of neonatal mice after developmental exposure to diesel exhaust origin secondary organic aerosol

Presenter : Nway N.C., Fujitani Y., Hirano S., Mar O., Tin-Tin-Win-Shwe
Title : , Neurotoxicology, 63:155-165 (2017)
Original Paper
Evaluating the toxicity of TiO2-based nanoparticles to Chinese hamster ovary cells and Escherichia coli: a complementary experimental and computational approach

Presenter : Mikolajczyk A., Sizochenko N., Mulkiewicz E., Malankowska A., Nischk M, Jurczak P., Hirano S., Nowaczyk G., Zaleska-Medynska A., Leszczynski J., Gajewicz A., Puzyn T.
Title : , Beilstein Journal of Nanotechnolgy, 8:2171-2180 (2017)
Original Paper
Aggregation is a critical cause of poor transfer into the brain tissue of intravenously administered cationic PAMAM dendrimer nanoparticles

Presenter : Kurokawa Y., Sone H., Tin-Tin-Win-Shwe, Zeng Y., Kimura H., Koyama Y., Yagi Y., Matsui Y., Yamazaki M., Hirano S.
Title : , International Journal of Nanomedicine, 12:3967-3975 (2017)
Original Paper
Effects of PAMAM dendrimers with various surface functional groups and multiple generations on cytotoxicity and neuronal differentiation using human neural progenitor cells

Presenter : Zeng Y., Kurokawa Y., Tin-Tin-Win-Shwe, Zeng Q, Hirano S., Zhang Z., Sone H.
Title : , The Journal of Toxicological Sciences, 41(3):351-370 (2016)
Original Paper
Distribution and Excretion of Arsenic Metabolites after Oral Administration of Seafood-Related Organoarsenicals in Rats

Presenter : Kobayashi Y., Hirano S.
Title : , Metals, 6(10):231-246 (2016)
Original Paper
Exposure of BALB/c Mice to Diesel Engine Exhaust Origin Secondary Organic Aerosol (DE-SOA) during the Developmental Stages Impairs the Social Behavior in Adult Life of the Males

Presenter : Tin-Tin-Win-Shwe, Chaw Kyi-Tha-Thu, Yadanar Moe, Fujitani Y., Shinji Tsukahara, Hirano S.
Title : , Fronters in Neuroscience, 25(9):524-1-524-10 (2016)
Original Paper
Combined experimental and computational approach to developing efficient photocatalysts based on Au/Pd–TiO2 nanoparticles

Presenter : Mikolajczyk A., Nowaczyk G., Gajewicz A., Hirano S., Jurga S., Zaleska-Medynska A., Puzyn T.
Title : , Environmental Science: Nano (2016)
Original Paper
The role of Rho-kinases in IL-1β release through phagocytosis of fibrous particles in human monocytes.

Presenter : Kanno S., Hirano S., Chiba S., Takeshita H., Nagai T., Takaeda M., Mukai T.
Title : , Archives of Toxicology, 89:73-85 (2015)
Original Paper
Particle deposition efficiency in air-liquid interface of a cell exposure chamber

Presenter : Fujitani Y., Sugaya Y., Hashiguchi M., Furuyama A., Hirano S., Takami A.
Title : , Journal of Aerosol Science, 81:90-99 (2015)
Original Paper
Difference in the toxicity mechanism between ion and nanoparticle forms of silver in the mouse lung and in macrophages

Presenter : Arai Y., Miyayama T., Hirano S.
Title : , Toxicology, 328:84-92 (2015)
Original Paper
Nano-Sized Secondary Organic Aerosol of Diesel Engine Exhaust Origin Impairs Olfactory-Based Spatial Learning Performance in Preweaning Mice

Presenter : Tin-Tin-Win-Shwe, Chaw Kyi Tha thu, Yadanar Moe, Maekawa F., Yanagisawa R., Furuyama A., Tsukahara, Fujitani Y., Hirano S.
Title : , Nanomaterials, 2015(5):1147-1162 (2015)
Original Paper
Solubility shift and SUMOylaltion of promyelocytic leukemia (PML) protein in response to arsenic(III) and fate of the SUMOylated PML

Presenter : Hirano S., Tadano M., Kobayashi Y., Udagawa O., KATO A.
Title : , Toxicology and Applied Pharmacology, 287:191-201 (2015)
Book
Atmospheric Nanoparticles and their Potential Health Effects

Presenter : Fujitani Y., Furuyama A., Hirano S.
Title : , PM2.5: Role of Oxidative Stress in Health Effects and Prevention Strategy (2015)
Original Paper
Repulsive apoptosis during exposure of mesencepharic neural stem cells to silver nanoparticles in a neurosphere assay in vitro

Presenter : Ishido M., Shimaya E., Kurokawa Y., Hirano S.
Title : , Current Drug Discovery Technologies, 12(1):43-51 (2015)
Book
Health Effects of Silver Nanoparticles and Silver Ions

Presenter : Miyayama T., Arai Y., Hirano S.
Title : , Biological Effects of Fibrous and Particulate Substances (2015)
Original Paper
Macrophage Receptor with Collagenous Structure (MARCO) Is Processed by either Macropinocytosis or Endocytosis-Autophagy Pathway

Presenter : Hirano S., Kanno S.
Title : , Plos ONE, 10(11):e0142062-e0142062 (2015)
Original Paper
A Novel Genotoxicity Assay of Carbon Nanotubes Using Functional Macrophage Receptor with Collagenous Structure (MARCO)-Expressing Chicken B Lymphocytes.

Presenter : Mohiuddin, Islam Shamima Keka, Terry John Evans, Kouji Hirota, Hiroyasu Shimizu, Koichi Kono, Shunichi Takeda, Hirano S.
Title : , Archives of Toxicology, 88:145-160 (2014)
Original Paper
Effects of PAMAM dendrimers in the mouse brain after a singleintranasal instillation

Presenter : Tin-Tin-Win-Shwe, Sone H., Kurokawa Y., Zeng Y., Zeng Q, Nitta H., Hirano S.
Title : , Toxicoloy Letters, 228(3):207-215 (2014)
Original Paper
Effects of Diesel Engine Exhaust Origin Secondary Organic Aerosols on Novel Object Recognition Ability and Maternal Behavior in BALB/C Mice

Presenter : Tin-Tin-Win-Shwe, Fujitani Y., Chaw Kyi ThaThu, Furuyama A., Michikawa T., Tsukahara S, Nitta H., Hirano S.
Title : , International Journal Of Environmental Research and Public Health, 11:11286-11307 (2014)
Original Paper
Mitochondrial electron transport is inhibited by disappearance of metallothionein in human bronchial epithelial cells following exposure to silver nitrate

Presenter : Miyayama T. , Arai Y., Suzuki N., Hirano S.
Title : , Toxicology, 305:20-29 (2013)
Original Paper
The role of glutathione in the metabolism of diphenylarsinic acid in rats.

Presenter : Kobayashi Y., Hirano S.
Title : , Metallomics, 5:469-478 (2013)
Original Paper
Effects of acute single intranasal instillation of secondary organic aerosol on neurological and immunological biomarkers in the brain and lung of BALB/c mice

Presenter : Tin-Tin-Win-Shwe, Fujitani Y., Sone H., Furuyama A., Nitta H., Hirano S.
Title : , The Journal of Toxicological Sciences, 38(1):71-82 (2013)
Original Paper
Effect of exposure to nanoparticle-rich or delpeted diesel exhaust on allergic pathophysiology in the murine lung

Presenter : Tanaka M., Aoki Y., Takano H., Fujitani Y., Hirano S., Nakamura R., Sone Y., Kiyono M., Ichinose T., Itoh T., Inoue K.
Title : , Journal of Toxicological Sciences, 38(1):35-48 (2013)
Review
Metabolism of arsenic and its toxicological relevance

Presenter : Watanabe T., Hirano S.
Title : , Archives of Toxicology, 87:969-979 (2013)
Original Paper
Sulfide induces apoptosis and Rho kinase-dependent cell blebbing in Jurkat cells

Presenter : Kanno S., Hirano S., Sagi M., Chiba S., Takeshita H., Ikawa T., Ichiba K., Nagai T., Takada M., Sakamoto K., Mukai T.
Title : , Archives of Toxicology, 87:1245-1256 (2013)
Original Paper
Effects of exposure to nanoparticle-rich diesel exhaust on 8-OHdG synthesis in the mouse asthmatic lung

Presenter : Tanaka K., Takano H., Fujitani Y., Hirano S., Ichinose T., Shimada A., Inoue Ken-ichiro
Title : , EXPERIMENTAL AND THERAPEUTIC MEDICINE, 6:703-706 (2013)
Original Paper
Effects of arsenic on modification of promyelocytic leukemia (PML): PML responds to low levels of arsenite

Presenter : Hirano S., Watanabe T., Kobayashi Y.
Title : , Toxicology and Applied Pharmacology, 273:590-599 (2013)
Original Paper
Developmental Subchronic Exposure to Diphenylarsinic Acid Induced Increased Exploratory Behavior, Impaired Learning Behavior, and Decreased Cerebellar Glutathione Concentration in Rats

Presenter : Negishi T., Matsunaga Y, Kobayashi Y., Hirano S., Tashiro T.
Title : , Toxicological Sciences, 136(2):478-486 (2013)
Original Paper
Macrophage receptor with collagenous structure (MARCO) is a dynamic adhesive molecule that enhances uptake of carbon nanotubes by CHO-K1 Cells

Presenter : Hirano S., Fujitani Y., Furuyama A., Kanno S.
Title : , Toxicology and Applied Pharmacology , 259(1):96-103 (2012)
Original Paper
Diphenylarsinic acid increased the synthesis and release of neuroactive and vasoactive peptides in rat cerebellar astrocytes

Presenter : Negishi T, Takahashi M, Matsunaga Y., Hirano S., Tashiro T
Title : , Journal of Neuropathology and Experimental Neurology, 71(6):468-479 (2012)
Original Paper
Effect of isothermal dilution on emission factors of organic carbon and n-alkanes in the particle and gas phases of diesel exhaust

Presenter : Fujitani Y., Saitoh K., Fushimi A., Takahashi K., Hasegawa S., Tanabe K., Kobayashi S., Furuyama A., Hirano S., Takami A.
Title : , Atmospheric Environment, 59:389-397 (2012)
Original Paper
Novel object recognition ability in female mice following exposure to nanoparticle-rich diesel exhaust

Presenter : Tin-Tin-Win-Shwe, Fujimaki H., Fujitani Y., Hirano S.
Title : , Toxicology and Applied Pharmacology, 262:355-362 (2012)
Original Paper
Nanoparticle-rich diesel exhaust affects hippocampal-dependent spatial learning and NMDA receptor subunit expression in female mice

Presenter : Tin-Tin-Win-Shwe, Yamamoto S., Fujitani Y., Hirano S., Fujimaki H.
Title : , Nanotoxicology, 6(5):543-553 (2012)
Original Paper
Seasonal differences of the atmospheric particle size distribution in a metropolitan area in Japan

Presenter : Fujitani Y., Kumar P., Tamura K., Fushimi A., Hasegawa S., Takahashi K., Tanabe K., Kobayashi S., Hirano S.
Title : , Science of the Total Environment, 437:339-347 (2012)
Original Paper
Effects of nanoparticle-rich diesel exhaust particles on IL-17 production in vitro

Presenter : Nakamura R., Inoue K., Fujitani Y., Kiyono M., Hirano S., Takano H.
Title : , Journal of Immunotoxicology, 9(1):72-76 (2012)
Original Paper
Simultaneous analysis of cardiac glycosides in blood and urine by thermoresponsive LC-MS-MS

Presenter : Kanno S., Watanabe K., Yamagishi I., Hirano S., Minakata K., Gonmori K., Suzuki O.
Title : , Anal.Bioanal.Chem., 399(3):1141-1149 (2011)
Original Paper
Nasal instillation of nanoparticle-rich diesel exhaust particles slightly affects emotional behavior and learning capability in rats

Presenter : Yokota S., Takashima H., Ohta R., Saito Y,, Miyahara T., Yoshida Y., Negura T., Senuma M., Usumi K., Hirabayashi N., Watanabe T., Horiuchi S., Fujitani Y., Hirano S., Fujimaki H.
Title : , The Journal of Toxicological Sciences, 36(3):267-276 (2011)
Original Paper
In vitro effects of nanoparticle-rich diesel exhaust particles on splenic mononuclear cells

Presenter : Inoue Ken-ichiro, Fujitani Y., Masako Kiyono, Hirano S., Takano H.
Title : , Immunopharmacology and Immunotoxicology, 33(3):519-524 (2011)
Other Publications
In vitro study of the effect of nanoparticle-rich diesel exhaust particles on IL-18 production in splenocytes

Presenter : Nakamura R., Inoue K., Fujitani Y., Kiyono M., Hirano S., Takano H.
Title : , The Journal of Toxicological Sciences, 36(6):823-827 (2011)
Original Paper
Identification of arsenite-and arsenic diglutathione-binding proteins in human hepatocarcinoma cells

Presenter : Mizumura Ayano, Watanabe Takayuki, Kobayashi Y., Hirano S.
Title : , Toxicol.Appl.Pharmacol., 242(2):119-125 (2010)
Original Paper
Characterization of dilution conditions for diesel nanoparticle inhalation studies

Presenter : Fujitani Y., Hirano S., Kobayashi S., Tanabe K., Suzuki A.K., Furuyama A., Kobayashi T.
Title : , Inhal.Toxicol., 21(3):200-209 (2009)
Original Paper
Extrapulmonary translocation of intratracheally instilled fine and ultrafine particles via direct and alveolar macrophage-associated routes

Presenter : Furuyama A., Kanno S., Kobayashi T., Hirano S.
Title : , Arch.Toxicol., 83(5):429-437 (2009)
Original Paper
Generation of airborne multi-walled carbon nanotubes for inhalation studies

Presenter : Fujitani Y., Furuyama A., Hirano S.
Title : , Aerosol Sci.Technol., 43(9):881-890 (2009)
Original Paper
Extracellular glutamate level and NMDA receptor subunit expression in mouse olfactory bulb following nanoparticle-rich diesel exhaust exposure

Presenter : Tin-Tin-Win-Shwe, Mitsushima D., Yamamoto S., Fujitani Y., Funabashi T., Hirano S., Fujimaki H.
Title : , Inhal.Toxicol., 21(10):828-836 (2009)
Original Paper
Effects of multi-walled carbon nanotubes on a murine allergic airway inflammation model

Presenter : Inoue Ken-ichiro, Koike E., Yanagisawa R., Hirano S., Nishikawa M., Takano H.
Title : , Toxicol.Appl.Pharmacol., 237(3):306-316 (2009)
Original Paper
Speciation analysis of selenium metabolites in urine and breath by HPLC-and GC-inductively coupled Plasma-MS after administration of selenomethionine and methylselenocysteine to rats

Presenter : Ohta Yuki, Kobayashi Y., Konishi Sakae, Hirano S., Ohta Yuki
Title : , Chem.Res.Toxicol., 22(11):1795-1801 (2009)
Original Paper
Distribution and excretion of arsenic in cynomolgus monkey following repeated administration of diphenylarsinic acid

Presenter : Kobayashi Y., Negashi T., Mizumura A., Watanabe T., Hirano S.
Title : , Arch.Toxicol., 82:553-561 (2008)
Original Paper
Effects of endogenous hydrogen peroxide and glutathione on the stability of arsenic metabolites in rat bile

Presenter : Kobayashi Y., Hirano S.
Title : , Toxicol.Appl.Pharmacol., 232(1):33-40 (2008)
Original Paper
Spatial learning and memory function-related gene expression in the hippocampus of mouse exposed to nanoparticle-rich diesel exhaust

Presenter : Tin-Tin-Win-Shwe, Yamamoto S., Fujitani Y., Hirano S., Fujimaki H.
Title : , Neurotoxicology, 29(6):940-947 (2008)
Other Publications
Central nervous effect of organoarsenic compound

Presenter : Ishii K, Shibata Y., Hosoya T., Takeda T., Iwasaki N., Nakamagoe K., Itoh Y., Kaise T., Hirano S., Ishii K., Ishizaki M., Doi M., Shimojo N., Tamaoka A.
Title : , Persistent Organic Pollutants(POPs) Research in Asia, 387-392 (2008)
Expression and activity of arsenic methyltransferase Cyt19 in rat tissues

Presenter : HIRANO Seishiro
Title : , Environ.Toxicol.Pharmacol., 23:115-120 (2007)
Effects of inhaled nanoparticles on acute lung injury induced by lipopolysaccharide in mice

Presenter : Inoue Ken-ichiro., Takano H., Yanagisawa R., Hirano S., Kobayashi T., Fujitani Y., Shimada A.(*1), Yoshikawa T.(*2)
Title : , Toxicology, 238:99-110 (2007)
Induction of oxidative stress and inhibition of plasminogen activator inhibitor-1 production in endothelial cells following exposure to organic extracts of diesel exhaust particles and urban fine particles

Presenter : HIRANO Seishiro, , FURUYAMA Akiko, Koike E.
Title : , Arch.Toxicol., 80:154-162 (2006)
Effects of organic chemicals derived from ambient particulate matter on lung inflammation related to lipopolysaccharide

Presenter : Inoue K., Takano H., Yanagisawa R., Hirano S., Kobayashi T., Ichinose T.(*1), Yoshikawa T.(*2)
Title : , Arch.Toxicol., 80:833-838 (2006)
Effects of airway exposure to nanoparticles on lung inflammation induced by bacterial endotoxin in mice

Presenter : Hirano S., Takano H., Yanagisawa R, Inoue K.
Title : , Environ.Health Perspect., 114(9):1325-1330 (2006)
The role of toll-like receptor 4 in airway inflammation induced by diesel exhaust particles

Presenter : Inoue K., Takano H., Yanagisawa R., Hirano S., Ichinose T.(*1), Shimada A.(*2), Yoshikawa T.(*3)
Title : , Arch.Toxicol., 80:275-279 (2006)
Toxicity of a trivalent organic arsenic compound,dimethylarsinous glutathione in a rat liver cell line(TRL 1215)

Presenter : HIRANO Seishiro
Title : , Br.J.Pharmacol., 149:888-897 (2006)
The role of glutathione in the metabolism and detoxification of trivalent arsenicals

Presenter : HIRANO Seishiro
Title : , Biomed.Res.Trace Elements, 17(4):365-372 (2006)
Chronic oral exposure to inorganic arsenate interferes with methylation status of p16INK4a and RASSF1A and induces lung cancer in A/J mice

Presenter : HIRANO Seishiro
Title : , Toxicol.Sci., 91(2):372-381 (2006)
Arsenic trioxide inhibits DNA methyltransferase and restores methylation-silenced genes in human liver cancer cells

Presenter : HIRANO Seishiro
Title : , Human Pathol., 37:298-311 (2006)
Cytotoxic effects of S-(dimethylarsino)-glutathione: A putative intermediate metabolite of inorganic arsenicals

Presenter : HIRANO Seishiro
Title : , Toxicology, 227:45-52 (2006)
Quantitative risk analysis of particulate matter in the Air: Interspecies extrapolation with bioassay and mathematical models

Presenter : Maruyama W., Hirano S., Kobayashi T., Aoki Y.
Title : , Inhal.Toxicol., 18:1013-1023 (2006)
Accumulation and toxicity of monophenyl arsenicals in rat endothelial cells

Presenter : HIRANO Seishiro,
Title : , Arch.Toxicol., 79:54-61 (2005)
Stability of arsenic metabolites,arsenic triglutathione [As(GS)3] and methylarsenic diglutathione [CH3As(GS)2],in rat bile

Presenter : HIRANO Seishiro
Title : , Toxicology, 211:115-123 (2005)
A new metabolic pathway of arsenite: arsenic-glutathione complexes are substrates for human arsenic methyltransferase Cyt19

Presenter : HIRANO Seishiro
Title : , Arch.Toxicol., 79:183-191 (2005)
Subchronic exposure to arsenic through drinking water alters expression of cancer-related genes in rat liver

Presenter : HIRANO Seishiro,
Title : , Toxicol.Pathol., 32:64-72 (2004)
Effects of phytoestrogens and environmental estrogens on osteoblastic differentiation in MC3T3-E1 cells

Presenter : Kanno S, Hirano S., Kayama F.(*1)
Title : , Toxicology, 196:137-145 (2004)
The accumulation and toxicity of methylated arsenicals in endothelial cells: important roles of thiol compounds

Presenter : HIRANO Seishiro
Title : , Toxicol.Appl.Pharmacol., 198:458-467 (2004)
cDNA microarray analysis of rat alveolar epithelial cells following exposure to organic extract of diesel exhaust particles

Presenter : HIRANO Seishiro, , FURUYAMA Akiko, Koike E.
Title : , Toxicol.Appl.Pharmacol., 201(2):178-185 (2004)
Arsenic speciation in bile and urine following oral and intravenous exposure to inorganic arsenic in rat

Presenter : HIRANO Seishiro
Title : , Toxicol.Sci., 82(2):478-487 (2004)
Nanoparticles in emissions and atmospheric environment-now and future

Presenter : Hirano S., Nitta H., Moriguchi Y., Kobayashi S., Kondo Y., Tanabe K., Kobayashi T., Wakamatsu S., Morita M., Yamazaki S.(*1)
Title : , J.Nanoparticle Res., 5:311-321 (2003)
Difference in uptake and toxicity of trivalent and pentavalent inorganic arsenic in rat heart microvessel endothelial cells

Presenter : HIRANO Seishiro
Title : , Arch.Toxicol., 77:305-312 (2003)
Arsenic speciation in the urine and hair of individuals exposed to airborne arsenic through coal-burning in Guizhou,PR China

Presenter : HIRANO Seishiro
Title : , Toxicol.Lett., 137:35-48 (2003)
Oxidative-stress potency of organic extracts of diesel exhaust and urban fine particles in rat heart microvessel endothelial cells

Presenter : HIRANO Seishiro, , FURUYAMA Akiko, Koike E.
Title : , Toxicology, 187:161-170 (2003)
cDNA microarray analysis of gene expression in rat alveolar macrophages in response to organic extract of diesel exhaust particles

Presenter : HIRANO Seishiro, , Koike E.
Title : , Toxicol.Sci., 67:241-246 (2002)
Effects of 17beta-estradiol,phytoestrogens and environmental estogens on osteoblastic differentiation in MC3T3-E1 cells

Presenter : HIRANO Seishiro
Title : , Biomed.Res.Trance Elem., 13(4):328-329 (2002)
Myeloperoxidase-associated tyrosine nitration after intratracheal administration of lipopolysaccbaride in rats

Presenter : Hataishi R.(*1), Kobayashi H.(*1), Takahashi Y.(*1), Hirano S., Zapol W.M.(*2), Jones R.C.(*2)
Title : , Anesthesiology, 97(4):887-895 (2002)
krox-20/egr-2 is up-regulated following non-specific and homophilic adhesion in rat macrophages

Presenter : HIRANO Seishiro
Title : , Immunology, 107:86-92 (2002)
Speciation of arsenic in tube-well water samples collected from West Bengal,India, by high-performance liquid chromatography-inductively coupled plasma mass spectrometry

Presenter : HIRANO Seishiro
Title : , Appl.Organometal.Chem., 16:202-209 (2002)
Extraction and speciation of arsenic in hair using HPLC-ICPMS

Presenter : HIRANO Seishiro
Title : , Anal.Sci., 17(Suppl.):i1729-i1732 (2001)
Chemotactic responses of osteoblastic MC3T3-E1 cells toward zinc chloride

Presenter : HIRANO Seishiro
Title : , Biol.Trace Elem.Res., 83:49-55 (2001)
Localization of zinc after in vitro mineralization in osteoblastic cells

Presenter : HIRANO Seishiro
Title : , Biol.Trace Elem.Res., 83:39-47 (2001)
Oxidative damage to mitochondria is a preliminary step to caspase-3 activation in fluoride-induced apoptosis in HL-60 cells

Presenter : HIRANO Seishiro
Title : , Free Radical Biol.Med., 31(3):367-373 (2001)
RGD peptide-induced apoptosis in human leukemia HL-60 cells requires caspase-3 activation

Presenter : HIRANO Seishiro
Title : , Cell Biol.Toxicol., 16:275‐283 (2000)
Transcription of krox-20/egr-2 is upregulated after exposure to fibrous particles and adhesion in rat alveolar macrophages

Presenter : HIRANO Seishiro
Title : , Am.J.Respir.Cell Mol.Biol., 23:313‐319 (2000)
Fluoride induces apoptosis by caspase-3 activation in human leukemia HL-60 cells

Presenter : HIRANO Seishiro
Title : , Arch.Toxicol., 74:226‐230 (2000)
Type I Collagen is a Non-Adhesive Extracelluar Matrix for Macrophages

Presenter : HIRANO Seishiro
Title : , Arch.Histol.Cytol., 63(1):71‐79 (2000)
Studies on the nature and significance of collagen in experimentally induced oral submucous fibrosis in rats

Presenter : HIRANO Seishiro
Title : , J.Clin.Biochem.Nutr., 27:123‐130 (1999)
Upregulation of heme oxygenase gene expressin in rat lung epithelial cells following exposure to cadmium

Presenter : HIRANO Seishiro
Title : , Arch.Toxicol., 73:410‐412 (1999)
Inflammatory responses of rat alveolar macrophages following exposure to fluoride

Presenter : HIRANO Seishiro
Title : , Arch.Toxicol., 73:310‐315 (1999)
Syk and paxillin are differentially phosphorylated following adhesion to the plastic substrate in rat alveolar macrophages

Presenter : HIRANO Seishiro
Title : , Immunology, 97(3):414‐419 (1999)
Inhaled Nitric Oxide Reduces Tyrosine Nitration after Lipopolysaccharide Instillation into Lungs of Rats

Presenter : HIRANO Seishiro
Title : , Am.J.Respir.Crit.Care Med., 160:678‐688 (1999)
Effects of Yttrium Chloride on the Lung

Presenter : HIRANO Seishiro
Title : , Comparative Evaluation of Environmental Toxicants(Inaba J.,Nakamura Y. ed.,Kodansha Sci.Ltd,311p.), 227‐232 (1998)
Effects of intratracheal pretreatment with yttrium chloride (YCL3) on inflammatory responses of the rat lung following intratracheal instillation of YCL3

Presenter : HIRANO Seishiro
Title : , Toxicol.Lett., 99:43‐51 (1998)
Nitric oxide-mediated cytotoxic effects of alveolar macrophages on transformed lung epithelial cells are independent of the b2 integrin-mediated intercellular adhesion

Presenter : HIRANO Seishiro
Title : , Immunology, 93:102‐108 (1998)
Fluoride mediates apoptosis in osteosarcoma UMR 106 and its cytotoxicity depends on the pH

Presenter : HIRANO Seishiro
Title : , Arch.Toxicol., 72:52‐58 (1997)
Quantitative Time-Course Profiles of Bronchoalveolar Lavage Cells Following Intratracheal Instillation of Lipopolysaccharide in Mice

Presenter : HIRANO Seishiro
Title : , Ind.Health, 35:353‐358 (1997)
In vitro and in vivo cytotoxic effects of nitric oxide on metastatic cells

Presenter : HIRANO Seishiro
Title : , Cancer Lett., 115:57‐62 (1997)
Comparison of pulmonary toxicity of yttrium chloride (YCl3) between saline and Ycl3 pretreated rats

Presenter : HIRANO Seishiro
Title : , Metal Ions Biol.& Med., 4:493‐495 (1996)
Migratory responses of PMN after intraperitoneal and intratracheal administration of lipopolysaccharide

Presenter : HIRANO Seishiro
Title : , Am.J.Physiol., 270:L836‐L845 (1996)
Exposure,Metabolism,and toxicity of rare earths and related compounds

Presenter : HIRANO Seishiro
Title : , Environ.Health Perspect., 104(1):85‐95 (1996)
Apoptotic cell death following exposure to fluoride in rat alveolar macrophages

Presenter : HIRANO Seishiro
Title : , Arch.Toxicol., 70:249‐251 (1996)
Interaction of rat alveolar macrophages with pulmonary epithelial cells following exposure to lipopolysaccharide

Presenter : HIRANO Seishiro
Title : , Arch.Toxicol., 70:230‐236 (1996)
Effects of gadolinium chloride on the rat lung following intratracheal instillation

Presenter : HIRANO Seishiro
Title : , Fundam.Appl.Toxicol., 28:65‐70 (1995)
Metabolism of leukotriene B4 by rat polymorphonuclear leukocytes

Presenter : HIRANO Seishiro
Title : , Jpn.J.Toxicol.Environ.Health, 41:15 (1995)
Pulmonary clearance and inflammatory potency of intratracheally instilled or acutely inhaled nickel sulfate in rats

Presenter : HIRANO Seishiro
Title : , Arch.Toxicol., 68:548‐554 (1994)
Correlation between inflammatory cellular responses and chemotactic activity in bronchoalveolar lavage fluid following intratracheal instillation of nickel sulfate in rats

Presenter : HIRANO Seishiro
Title : , Arch.Toxicol., 68:444‐449 (1994)
Metabolism and toxicity of intravenously injected yttrium chloride in rats

Presenter : HIRANO Seishiro
Title : , Toxicol.Appl.Pharmacol., 121:224‐232 (1993)
Energy restriction that inhibits cellular proliferation by torpor can decrease susceptibility to spontaneous and asbestos-induced lung tumors in A/J mice

Presenter : HIRANO Seishiro
Title : , Lab.Invest., 68:728‐739 (1993)
Pulmonary clearance and toxicity of intratracheally instilled cupric oxide in rats

Presenter : HIRANO Seishiro,
Title : , Arch.Toxicol., 67:312‐317 (1993)
Identification of metabolites of 2-chlorodibenzofuran in the rat

Presenter : , HIRANO Seishiro, ,
Title : , Arch.Environ.Contam.Toxicol., 20:67‐72 (1991)
Changes in element concentration and distribution in breast-milk fractions of a healthy lactating mother

Presenter : HIRANO Seishiro
Title : , Biol.Trace Elem.Res., 28:109‐121 (1991)
Inflammatory responses in the rat lung following intratracheal instillation of nickel sulfate

Presenter : HIRANO Seishiro
Title : , Eisei Kakgaku, 37:13 (1991)
Metabolism and pulmonary toxicity of intratracheally instilled cupric sulfate in rats

Presenter : HIRANO Seishiro,
Title : , Toxicology, 64:223‐233 (1990)
Distribution and localization of yttrium in the rat lung following intratracheal instillation

Presenter : HIRANO Seishiro
Title : , Eisei Kagaku, 36:27 (1990)
Biochemical changes in the rat lung and liver following intratracheal instillation of cadmium oxide

Presenter : HIRANO Seishiro
Title : , Toxicol.Lett., 50:97‐105 (1990)
Pulmonary clearance and toxicity of zinc oxide instilled into the rat lung

Presenter : HIRANO Seishiro
Title : , Arch.Toxicol., 63:336‐342 (1989)
Toxicity of cadmium oxide instilled into the rat lung.II.Inflammatory responses in broncho-alveolar lavage fluid

Presenter : HIRANO Seishiro
Title : , Toxicology, 55:25‐35 (1989)
Toxicity of cadmium oxide instilled into the rat lung.I.Metabolism of cadmium oxide in the lung and its effects on essential elements

Presenter : HIRANO Seishiro
Title : , Toxicology, 55:15‐24 (1989)
Metabolic behavior and pulmonary toxicity of zinc oxide instilled into rat lung

Presenter : HIRANO Seishiro
Title : , Eisei Kagaku, 35:S‐19 (1989)
Functional and Biochemical effects on rat lung following instillation of crocidolite and chrysotile asbestos

Presenter : HIRANO Seishiro,
Title : , J.Toxicol.Environ.Health, 24:27‐39 (1988)
Automatic control of aerosol concentrations in exposure chambers

Presenter : HIRANO Seishiro
Title : , Am.Ind.Hyg.Assoc.J., 48(12):972‐976 (1987)
A proportional method for the dilution of submicron hygroscopic aerosols

Presenter : HIRANO Seishiro
Title : , Am.Ind.Hyg.Assoc.J., 48(12):969‐971 (1987)
Enhanced IgE antibody production in mice injected with fly ash

Presenter : HIRANO Seishiro,
Title : , Int.Arch.Allergy Appl.Immunol., 80:127‐131 (1986)
Transfer of hexachlorobenzene (HCB) from mother to new-born baby through placenta and milk

Presenter : HIRANO Seishiro
Title : , Arch.Toxicol., 56:195‐200 (1985)

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Cellular uptake of paraquat determines subsequent toxicity including mitochondrial damage in lung epithelial cells

Presenter : Kanno S., Hirano S., Mukai T., Ro A., Fukuta M., Aoki Y.
Title : , Legal Medicine, 37:7-14 (2019)
Influence of polymeric precursors on the viability of human cells of yttrium aluminum borates nanoparticles doped with ytterbium ions

Presenter : Cieslik I., Plocinska M., Plocinski T., Zdunek J., Wozniak M.J., Bil M., Hirano S.
Title : , Applied Surface Science, 488:874-886 (2019)
Effects of diesel exhaust derived secondary organic aerosol (DE-SOA) exposure during developmental period on anxiety and depression in mice

Presenter : Tin-Tin-Win-Shwe, Fujitani Y., Hirano S.
Title : , Indoor Environment, 22(1):23-32 (2019)
Effects of diesel exhaust-derived secondary organic aerosol (SOA) on oocytes: Potential risks to meiotic maturation

Presenter : Udagawa O., Furuyama A., Imai K., Fujitani Y., Hirano S.
Title : , Reproductive Toxicology, 75:56-64 (2018)
Nano-QSAR modeling for ecosafe design of heterogeneous TiO2-based nano-photocatalysts

Presenter : Mikolajczyk A., Gajewicz A., Mulkiewicz E., Rasulev B., Marchelek M., Diak M., Hirano S., Zaleska-Medynska A., Puzyn T.
Title : , Environmental Science Nano, 1 (2018)
Potassium gadolinium tungstate nanocrystals doped with holmium ions as candidates for optical imaging

Presenter : Cieślik I., Bolek T., Woźniak M.J., Majchrowski A., Hirano S.
Title : , Applied Surface Science, 446:139-144 (2018)
Solubility changes of promyelocytic leukemia (PML) and SUMO monomers and dynamics of PML nuclear body proteins in arsenite-treated cells

Presenter : Hirano S., Udagawa O., Kobayashi Y., Kato A.
Title : , Toxicology and Applied Pharmacology, 360:150-159 (2018)
Characterization and influence of hydroxyapatite nanopowders on living cells

Presenter : Oberbek P., Bolek T., Chlanda A., Hirano S., Kusnieruk S., Rogowska-Tylman J., Nechyporenko G., Zinchenko V., Swieszkowski W., Puzyn P.
Title : , Beilstein Journal of Nanotechnology, 9:3079-3094 (2018)
Pharmacodynamics of S-dimethylarsino-glutathione, a putative metabolic intermediate of inorganic arsenic, in mice

Presenter : Kato A., Kobayashi Y., Udagawa O., Hirano S.
Title : , Biochemical Pharmacology, 126:79-86 (2017)
Oxidative stress and cytotoxic effects of silver ion in mouse lung macrophages J774.1 cells

Presenter : Ilseob Shim, Kyunghee Choi, Hirano S.
Title : , Journal of Applied Toxicology, 37:471-478 (2017)
Comparison of Oxidative Abilities of PM2.5 Collected at Traffic and Residential Sites in Japan. Contribution of Transition Metals and Primary and Secondary Aerosols

Presenter : Fujitani Y., Furuyama A., Tanabe K., Hirano S.
Title : , Aerosol and Air Quality Research, 17:574-587 (2017)
Neurotoxicity Assessment of Secondary Organic Aerosol by Intranasal and Inhalation Exposure in Mice

Presenter : Tin-Tin-Win-Shwe, Fujitani Y., Hirano S.
Title : , Earozoru Kenkyu, 32(3):169-175 (2017)
Differential Regulation of IL-1β and IL-6 Release in Murine Macrophages

Presenter : Hirano S., Zhou Q., Furuyama A., Kanno S.
Title : , Inflammation, 40(6):1933-1943 (2017)
Role of TLR4 in olfactory-based spatial learning activity of neonatal mice after developmental exposure to diesel exhaust origin secondary organic aerosol

Presenter : Nway N.C., Fujitani Y., Hirano S., Mar O., Tin-Tin-Win-Shwe
Title : , Neurotoxicology, 63:155-165 (2017)
Evaluating the toxicity of TiO2-based nanoparticles to Chinese hamster ovary cells and Escherichia coli: a complementary experimental and computational approach

Presenter : Mikolajczyk A., Sizochenko N., Mulkiewicz E., Malankowska A., Nischk M, Jurczak P., Hirano S., Nowaczyk G., Zaleska-Medynska A., Leszczynski J., Gajewicz A., Puzyn T.
Title : , Beilstein Journal of Nanotechnolgy, 8:2171-2180 (2017)
Aggregation is a critical cause of poor transfer into the brain tissue of intravenously administered cationic PAMAM dendrimer nanoparticles

Presenter : Kurokawa Y., Sone H., Tin-Tin-Win-Shwe, Zeng Y., Kimura H., Koyama Y., Yagi Y., Matsui Y., Yamazaki M., Hirano S.
Title : , International Journal of Nanomedicine, 12:3967-3975 (2017)
Effects of PAMAM dendrimers with various surface functional groups and multiple generations on cytotoxicity and neuronal differentiation using human neural progenitor cells

Presenter : Zeng Y., Kurokawa Y., Tin-Tin-Win-Shwe, Zeng Q, Hirano S., Zhang Z., Sone H.
Title : , The Journal of Toxicological Sciences, 41(3):351-370 (2016)
Distribution and Excretion of Arsenic Metabolites after Oral Administration of Seafood-Related Organoarsenicals in Rats

Presenter : Kobayashi Y., Hirano S.
Title : , Metals, 6(10):231-246 (2016)
Exposure of BALB/c Mice to Diesel Engine Exhaust Origin Secondary Organic Aerosol (DE-SOA) during the Developmental Stages Impairs the Social Behavior in Adult Life of the Males

Presenter : Tin-Tin-Win-Shwe, Chaw Kyi-Tha-Thu, Yadanar Moe, Fujitani Y., Shinji Tsukahara, Hirano S.
Title : , Fronters in Neuroscience, 25(9):524-1-524-10 (2016)
Combined experimental and computational approach to developing efficient photocatalysts based on Au/Pd–TiO2 nanoparticles

Presenter : Mikolajczyk A., Nowaczyk G., Gajewicz A., Hirano S., Jurga S., Zaleska-Medynska A., Puzyn T.
Title : , Environmental Science: Nano (2016)
The role of Rho-kinases in IL-1β release through phagocytosis of fibrous particles in human monocytes.

Presenter : Kanno S., Hirano S., Chiba S., Takeshita H., Nagai T., Takaeda M., Mukai T.
Title : , Archives of Toxicology, 89:73-85 (2015)
Particle deposition efficiency in air-liquid interface of a cell exposure chamber

Presenter : Fujitani Y., Sugaya Y., Hashiguchi M., Furuyama A., Hirano S., Takami A.
Title : , Journal of Aerosol Science, 81:90-99 (2015)
Difference in the toxicity mechanism between ion and nanoparticle forms of silver in the mouse lung and in macrophages

Presenter : Arai Y., Miyayama T., Hirano S.
Title : , Toxicology, 328:84-92 (2015)
Nano-Sized Secondary Organic Aerosol of Diesel Engine Exhaust Origin Impairs Olfactory-Based Spatial Learning Performance in Preweaning Mice

Presenter : Tin-Tin-Win-Shwe, Chaw Kyi Tha thu, Yadanar Moe, Maekawa F., Yanagisawa R., Furuyama A., Tsukahara, Fujitani Y., Hirano S.
Title : , Nanomaterials, 2015(5):1147-1162 (2015)
Solubility shift and SUMOylaltion of promyelocytic leukemia (PML) protein in response to arsenic(III) and fate of the SUMOylated PML

Presenter : Hirano S., Tadano M., Kobayashi Y., Udagawa O., KATO A.
Title : , Toxicology and Applied Pharmacology, 287:191-201 (2015)
Repulsive apoptosis during exposure of mesencepharic neural stem cells to silver nanoparticles in a neurosphere assay in vitro

Presenter : Ishido M., Shimaya E., Kurokawa Y., Hirano S.
Title : , Current Drug Discovery Technologies, 12(1):43-51 (2015)
Macrophage Receptor with Collagenous Structure (MARCO) Is Processed by either Macropinocytosis or Endocytosis-Autophagy Pathway

Presenter : Hirano S., Kanno S.
Title : , Plos ONE, 10(11):e0142062-e0142062 (2015)
A Novel Genotoxicity Assay of Carbon Nanotubes Using Functional Macrophage Receptor with Collagenous Structure (MARCO)-Expressing Chicken B Lymphocytes.

Presenter : Mohiuddin, Islam Shamima Keka, Terry John Evans, Kouji Hirota, Hiroyasu Shimizu, Koichi Kono, Shunichi Takeda, Hirano S.
Title : , Archives of Toxicology, 88:145-160 (2014)
Effects of PAMAM dendrimers in the mouse brain after a singleintranasal instillation

Presenter : Tin-Tin-Win-Shwe, Sone H., Kurokawa Y., Zeng Y., Zeng Q, Nitta H., Hirano S.
Title : , Toxicoloy Letters, 228(3):207-215 (2014)
Effects of Diesel Engine Exhaust Origin Secondary Organic Aerosols on Novel Object Recognition Ability and Maternal Behavior in BALB/C Mice

Presenter : Tin-Tin-Win-Shwe, Fujitani Y., Chaw Kyi ThaThu, Furuyama A., Michikawa T., Tsukahara S, Nitta H., Hirano S.
Title : , International Journal Of Environmental Research and Public Health, 11:11286-11307 (2014)
Mitochondrial electron transport is inhibited by disappearance of metallothionein in human bronchial epithelial cells following exposure to silver nitrate

Presenter : Miyayama T. , Arai Y., Suzuki N., Hirano S.
Title : , Toxicology, 305:20-29 (2013)
The role of glutathione in the metabolism of diphenylarsinic acid in rats.

Presenter : Kobayashi Y., Hirano S.
Title : , Metallomics, 5:469-478 (2013)
Effects of acute single intranasal instillation of secondary organic aerosol on neurological and immunological biomarkers in the brain and lung of BALB/c mice

Presenter : Tin-Tin-Win-Shwe, Fujitani Y., Sone H., Furuyama A., Nitta H., Hirano S.
Title : , The Journal of Toxicological Sciences, 38(1):71-82 (2013)
Effect of exposure to nanoparticle-rich or delpeted diesel exhaust on allergic pathophysiology in the murine lung

Presenter : Tanaka M., Aoki Y., Takano H., Fujitani Y., Hirano S., Nakamura R., Sone Y., Kiyono M., Ichinose T., Itoh T., Inoue K.
Title : , Journal of Toxicological Sciences, 38(1):35-48 (2013)
Sulfide induces apoptosis and Rho kinase-dependent cell blebbing in Jurkat cells

Presenter : Kanno S., Hirano S., Sagi M., Chiba S., Takeshita H., Ikawa T., Ichiba K., Nagai T., Takada M., Sakamoto K., Mukai T.
Title : , Archives of Toxicology, 87:1245-1256 (2013)
Effects of exposure to nanoparticle-rich diesel exhaust on 8-OHdG synthesis in the mouse asthmatic lung

Presenter : Tanaka K., Takano H., Fujitani Y., Hirano S., Ichinose T., Shimada A., Inoue Ken-ichiro
Title : , EXPERIMENTAL AND THERAPEUTIC MEDICINE, 6:703-706 (2013)
Effects of arsenic on modification of promyelocytic leukemia (PML): PML responds to low levels of arsenite

Presenter : Hirano S., Watanabe T., Kobayashi Y.
Title : , Toxicology and Applied Pharmacology, 273:590-599 (2013)
Developmental Subchronic Exposure to Diphenylarsinic Acid Induced Increased Exploratory Behavior, Impaired Learning Behavior, and Decreased Cerebellar Glutathione Concentration in Rats

Presenter : Negishi T., Matsunaga Y, Kobayashi Y., Hirano S., Tashiro T.
Title : , Toxicological Sciences, 136(2):478-486 (2013)
Macrophage receptor with collagenous structure (MARCO) is a dynamic adhesive molecule that enhances uptake of carbon nanotubes by CHO-K1 Cells

Presenter : Hirano S., Fujitani Y., Furuyama A., Kanno S.
Title : , Toxicology and Applied Pharmacology , 259(1):96-103 (2012)
Diphenylarsinic acid increased the synthesis and release of neuroactive and vasoactive peptides in rat cerebellar astrocytes

Presenter : Negishi T, Takahashi M, Matsunaga Y., Hirano S., Tashiro T
Title : , Journal of Neuropathology and Experimental Neurology, 71(6):468-479 (2012)
Effect of isothermal dilution on emission factors of organic carbon and n-alkanes in the particle and gas phases of diesel exhaust

Presenter : Fujitani Y., Saitoh K., Fushimi A., Takahashi K., Hasegawa S., Tanabe K., Kobayashi S., Furuyama A., Hirano S., Takami A.
Title : , Atmospheric Environment, 59:389-397 (2012)
Novel object recognition ability in female mice following exposure to nanoparticle-rich diesel exhaust

Presenter : Tin-Tin-Win-Shwe, Fujimaki H., Fujitani Y., Hirano S.
Title : , Toxicology and Applied Pharmacology, 262:355-362 (2012)
Nanoparticle-rich diesel exhaust affects hippocampal-dependent spatial learning and NMDA receptor subunit expression in female mice

Presenter : Tin-Tin-Win-Shwe, Yamamoto S., Fujitani Y., Hirano S., Fujimaki H.
Title : , Nanotoxicology, 6(5):543-553 (2012)
Seasonal differences of the atmospheric particle size distribution in a metropolitan area in Japan

Presenter : Fujitani Y., Kumar P., Tamura K., Fushimi A., Hasegawa S., Takahashi K., Tanabe K., Kobayashi S., Hirano S.
Title : , Science of the Total Environment, 437:339-347 (2012)
Effects of nanoparticle-rich diesel exhaust particles on IL-17 production in vitro

Presenter : Nakamura R., Inoue K., Fujitani Y., Kiyono M., Hirano S., Takano H.
Title : , Journal of Immunotoxicology, 9(1):72-76 (2012)
Simultaneous analysis of cardiac glycosides in blood and urine by thermoresponsive LC-MS-MS

Presenter : Kanno S., Watanabe K., Yamagishi I., Hirano S., Minakata K., Gonmori K., Suzuki O.
Title : , Anal.Bioanal.Chem., 399(3):1141-1149 (2011)
Nasal instillation of nanoparticle-rich diesel exhaust particles slightly affects emotional behavior and learning capability in rats

Presenter : Yokota S., Takashima H., Ohta R., Saito Y,, Miyahara T., Yoshida Y., Negura T., Senuma M., Usumi K., Hirabayashi N., Watanabe T., Horiuchi S., Fujitani Y., Hirano S., Fujimaki H.
Title : , The Journal of Toxicological Sciences, 36(3):267-276 (2011)
In vitro effects of nanoparticle-rich diesel exhaust particles on splenic mononuclear cells

Presenter : Inoue Ken-ichiro, Fujitani Y., Masako Kiyono, Hirano S., Takano H.
Title : , Immunopharmacology and Immunotoxicology, 33(3):519-524 (2011)
Identification of arsenite-and arsenic diglutathione-binding proteins in human hepatocarcinoma cells

Presenter : Mizumura Ayano, Watanabe Takayuki, Kobayashi Y., Hirano S.
Title : , Toxicol.Appl.Pharmacol., 242(2):119-125 (2010)
Characterization of dilution conditions for diesel nanoparticle inhalation studies

Presenter : Fujitani Y., Hirano S., Kobayashi S., Tanabe K., Suzuki A.K., Furuyama A., Kobayashi T.
Title : , Inhal.Toxicol., 21(3):200-209 (2009)
Extrapulmonary translocation of intratracheally instilled fine and ultrafine particles via direct and alveolar macrophage-associated routes

Presenter : Furuyama A., Kanno S., Kobayashi T., Hirano S.
Title : , Arch.Toxicol., 83(5):429-437 (2009)
Generation of airborne multi-walled carbon nanotubes for inhalation studies

Presenter : Fujitani Y., Furuyama A., Hirano S.
Title : , Aerosol Sci.Technol., 43(9):881-890 (2009)
Extracellular glutamate level and NMDA receptor subunit expression in mouse olfactory bulb following nanoparticle-rich diesel exhaust exposure

Presenter : Tin-Tin-Win-Shwe, Mitsushima D., Yamamoto S., Fujitani Y., Funabashi T., Hirano S., Fujimaki H.
Title : , Inhal.Toxicol., 21(10):828-836 (2009)
Effects of multi-walled carbon nanotubes on a murine allergic airway inflammation model

Presenter : Inoue Ken-ichiro, Koike E., Yanagisawa R., Hirano S., Nishikawa M., Takano H.
Title : , Toxicol.Appl.Pharmacol., 237(3):306-316 (2009)
Speciation analysis of selenium metabolites in urine and breath by HPLC-and GC-inductively coupled Plasma-MS after administration of selenomethionine and methylselenocysteine to rats

Presenter : Ohta Yuki, Kobayashi Y., Konishi Sakae, Hirano S., Ohta Yuki
Title : , Chem.Res.Toxicol., 22(11):1795-1801 (2009)
Distribution and excretion of arsenic in cynomolgus monkey following repeated administration of diphenylarsinic acid

Presenter : Kobayashi Y., Negashi T., Mizumura A., Watanabe T., Hirano S.
Title : , Arch.Toxicol., 82:553-561 (2008)
Effects of endogenous hydrogen peroxide and glutathione on the stability of arsenic metabolites in rat bile

Presenter : Kobayashi Y., Hirano S.
Title : , Toxicol.Appl.Pharmacol., 232(1):33-40 (2008)
Spatial learning and memory function-related gene expression in the hippocampus of mouse exposed to nanoparticle-rich diesel exhaust

Presenter : Tin-Tin-Win-Shwe, Yamamoto S., Fujitani Y., Hirano S., Fujimaki H.
Title : , Neurotoxicology, 29(6):940-947 (2008)

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Biotransformation of arsenic and toxicological implication of arsenic metabolites

Presenter : Hirano S.
Title : , Archives of Toxicology, 94(8):2587-2601 (2020)
Metabolism of arsenic and its toxicological relevance

Presenter : Watanabe T., Hirano S.
Title : , Archives of Toxicology, 87:969-979 (2013)

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Atmospheric Nanoparticles and their Potential Health Effects

Presenter : Fujitani Y., Furuyama A., Hirano S.
Title : , PM2.5: Role of Oxidative Stress in Health Effects and Prevention Strategy (2015)
Health Effects of Silver Nanoparticles and Silver Ions

Presenter : Miyayama T., Arai Y., Hirano S.
Title : , Biological Effects of Fibrous and Particulate Substances (2015)

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In vitro study of the effect of nanoparticle-rich diesel exhaust particles on IL-18 production in splenocytes

Presenter : Nakamura R., Inoue K., Fujitani Y., Kiyono M., Hirano S., Takano H.
Title : , The Journal of Toxicological Sciences, 36(6):823-827 (2011)
Central nervous effect of organoarsenic compound

Presenter : Ishii K, Shibata Y., Hosoya T., Takeda T., Iwasaki N., Nakamagoe K., Itoh Y., Kaise T., Hirano S., Ishii K., Ishizaki M., Doi M., Shimojo N., Tamaoka A.
Title : , Persistent Organic Pollutants(POPs) Research in Asia, 387-392 (2008)

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Research Result (Presentation)

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Research Presentation
Research Lecture

Research Presentation
Perinatal diesel exhaust originated secondary organic aerosol exposure produces autism-like behaviors in offspring rats: comparison with valproic acid autistic model

Presenter : Tin-Tin-Win-Shwe, Fujitani Y., Hirano S.
Name of Society : 43rd Annual Meeting of the japan Neuroscience Society (2020)
Name of Proceedings : Abstract (P2-231)
Research Presentation
Effects of selenite on uptake of arsenite in rat erythrocytes

Presenter : Kobayashi Y., Suzuki N., Ogra Y., Hirano S.
Name of Society : The 18th International Conference of the Pacific Basin Consortium for Environment and Health (2019)
Name of Proceedings : -
Research Presentation
Alteration of social dominance behavior in rats after developmental exposure to secondary organic aerosol

Presenter : Tin-Tin-Win-Shwe, Fujitani Y., Hirano S.
Name of Society : The 42nd Annual Meeting of the Japan Neuroscience Society (2019)
Name of Proceedings : Abstract, 281
Research Presentation
Distribution, metabolism and excretion of arsenolipids in mice after oral administration.

Presenter : Kobayashi Y., Suzuki N., Ogra Y., Hirano S.
Name of Society : IUTOX 15th InternationalCongress of Toxicology (2019)
Name of Proceedings : Abstract, 164
Research Presentation
Developmental exposure to diesel exhaust-derived secondary organic aerosol (DE-SOA) on anxiety and depression in mice

Presenter : Tin-Tin-Win-Shwe, Fujitani Y., Hirano S.
Name of Society : 28th Symposium on Environmental Chemistry (2019)
Name of Proceedings : Abstract (Poster-134)
Research Presentation
Social dominance behavior and brain biomarkers after gestational and lactational exposure to secondary organic aerosol in male rats

Presenter : Tin-Tin-Win-Shwe, Fujitani Y., Hirano S.
Name of Society : 47th Myanmar Health Research Congress (2019)
Name of Proceedings : Abstract, 130
Research Presentation
Exposure assessment of barium sulfate particles in a factory

Presenter : Ichihara G., Huang Z., Ichihara S., Fujitani Y., Hirano S., Takeuchi S., Hirano A., Huang H.
Name of Society : NanoTox 2018 - 9th International Conference on Nanotoxicology (2018)
Name of Proceedings : Abstracts
Research Presentation
Study of toxicology in an active optical nanocrystals

Presenter : Cieslik I., Kurpaska L., Budzianowski A., Hirano S.
Name of Society : 13th International Conference on Surfaces, Coatings and Nanostructured Materials (2018)
Name of Proceedings : NANOSMAT 2018 Abstracts, 18
Research Presentation
Perinatal exposure to secondary organic aerosol influences neurobehavioral development and inflammatory markers in rats

Presenter : Tin-Tin-Win-Shwe, Fujitani Y., Hirano S.
Name of Society : 54th European Societies of Toxicology Meeting (EUROTOX2018) (2018)
Name of Proceedings : Abstract, 133
Research Presentation
Developmental exposure to secondary organic aerosol alters social dominance behavior and expression of neuroimmune biomarkers in rats

Presenter : Tin-Tin-Win-Shwe, Nway N.C., Mar O., Watanabe H., Fujitani Y., Hirano S.
Name of Society : The 27th Symposium of Japan Environmental Chemistry (2018)
Name of Proceedings : Abstract, 536-537
Research Presentation
Effects of cationic disinfectants on surface activity of pulmonary surfactant monolayers

Presenter : Kanno S., Hirano S., Mukai T., Kato H., Aoki Y.
Name of Society : The 57st Annual Meeting of the Society of Toxicology (2018)
Name of Proceedings : Abstract, 252
Research Presentation
Developmental exposure to diesel exhaust origin secondary organic aerosol and role of TLR4 in olfactory-based spatial learning activity of neonatal mice

Presenter : Nway N.C., Fujitani Y., Mar O., Hirano S., Tin-Tin-Win-Shwe
Name of Society : 46th Myanmar Health Research Congress (2018)
Name of Proceedings : Abstract (Poster 21), 119
Research Presentation
Distribution and excretion of arsenic in mice after oral administration of arsenolipid

Presenter : Kobayashi Y., Suzuki N., Ogra Y., Hirano S.
Name of Society : The 6th International Symposium on Metallomics (2017)
Name of Proceedings : -
Research Presentation
Effects of diesel exhaust-derived secondary organic aerosol (SOA) on oocytes in mice

Presenter : Udagawa O., Furuyama A., Imai K., Fujitani Y., Hirano S.
Name of Society : 2017 Advanced Investigation in Mechanistic Toxicology, Gordon Research Conference (2017)
Name of Proceedings : Abstracts, 13
Research Presentation
Evaluation of neurotoxicity by air pollutant exposure using animal model

Presenter : Tin-Tin-Win-Shwe, Fujitani Y., Hirano S.
Name of Society : 44th Annual Meeting of the Japan Society of Toxicology (2017)
Name of Proceedings : Abstracts, S90
Research Presentation
Establishment of an olfactory-based spatial learning test for neonatal mice and the effects of perinatal exposure to diesel exhaust origin secondary organic aerosol

Presenter : Tin-Tin-Win-Shwe, Tha-Thu C.K., Moe Y., Fujitani Y., Tsukahara S., Hirano S.
Name of Society : 11th International Particle Toxicology Conference (2016)
Name of Proceedings : Abstract, 54
Research Presentation
Impact on the learning ability and neuro-immune biomarkers by diesel exhaust originated secondary organic aerosol exposure ディーゼル排気ガス由来二次有機エアロゾル曝露による学習能力と神経免疫バイオマーカーへの影響

Presenter : Tin-Tin-Win-Shwe, Fujitani Y., Hirano S.
Name of Society : 39th Annual Meeting of the Molecular Biology Society of Japan (2016)
Name of Proceedings : Abstarct, 137
Research Presentation
Role of toll-like receptor 4 in diesel exhaust origin secondary organic aerosol-induced impaired spatial learning ability in neonatal mice

Presenter : Tin-Tin-Win-Shwe, Fujitani Y., Watanabe H., Hirano S.
Name of Society : Society for Neuroscience 2016 (2016)
Name of Proceedings : Abstract, 61
Research Presentation
Distribution and speciation of arsenic in mice intravenously injected with S-dimethylarsino-glutathione

Presenter : KATO A., Kobayashi Y., Udagawa O., Hirano S.
Name of Society : 44th Myanmar health research congress (2016)
Name of Proceedings : Abstracts, 97-98
Research Presentation
Novel approach to olfactory-based spatial learning ability for preweaning mice and the effects of early exposure to diesel exhaust origin secondary organic aerosol

Presenter : Tin-Tin-Win-Shwe, Chaw Kyi Tha Thu, Yadanar Moe, Fujitani Y., Shinji Tsukahara, Maekawa F., Hirano S.
Name of Society : 44th Myanmar Health Research Congress (2016)
Name of Proceedings : Abstract, 79
Research Presentation
Enhanced particle deposition efficiency in air-liquid interface of a cell exposure chamber by electrostatic force

Presenter : Fujitani Y., Sugaya Y., Hashiguchi M., Furuyama A., Hirano S., Takami A.
Name of Society : The 2015 European Aerosol Conference (2015)
Name of Proceedings : Abstract
Research Presentation
Establishment of an olfactory-based spatial learning test for preweaning mice and the ef-fects of early exposure to diesel exhaust origin secondary organic aerosol

Presenter : Tin-Tin-Win-Shwe, Chaw Kyi-Tha Thu, Yadanar Moe, Fujitani Y., Shinji Tsukahara, Nitta H., Hirano S.
Name of Society : 51st Congress of the European Societies of Toxicology (2015)
Name of Proceedings : Abstract, 120
Research Presentation
Diesel engine exhaust origin secondary organic aerosol affects olfactory-based spatial learning performance and related gene expressions in preweaning mice

Presenter : Tin-Tin-Win-Shwe, Fujitani Y., Nohara K., Hirano S.
Name of Society : 第4回日本DOHaD研究会学術集会 (2015)
Name of Proceedings : Abtract, 115
Research Presentation
Arsenic toxicity on female reproduction in mice; molecular examination on how oocyte quality contributes.

Presenter : Udagawa O., KATO A., Kobayashi Y., Aoki Y., Hirano S.
Name of Society : 2015 Cellular & Molecular Mechanisms of Toxicity Gordon Research Conference (2015)
Name of Proceedings : Abstracts, 16
Research Presentation
Developmental exposure to diesel engine exhaust origin secondary organic aerosol on olfactory-based spatial learning performance in preweaning mice

Presenter : Tin-Tin-Win-Shwe, Fujitani Y., Furuyama A., Nitta H., Hirano S.
Name of Society : 第38回日本神経科学大会 (2015)
Name of Proceedings : Abstract(3P292), 250
Research Presentation
Transport of adnlinistered dendrimer nanoparticles to neura:tissue:in vitro and in vivo studies

Presenter : Kurokawa Y., Zeng Y., Tin-Tin-Win-Shwe, Kimura H, Koyama Y, Matsui Y, Hirano S., Sone H.
Name of Society : 第38回日本神経科学大会(The 38th Annual Meeting of the Japan Neuroscience Society) (2015)
Name of Proceedings : Abstracts
Research Lecture
Immune Responses to Different Classes of Inhaled Particulates: Unique vs. Shared Responses and Mechanisms.

Presenter : Hirano S., Hollian, A.
Name of Society : Society of Toxicology 54th Annual Meeting and ToxExpo (2015)
Name of Proceedings : Abstract, 178
Research Presentation
Developmental exposure to diesel engine exhaust origin secondary organic aerosol on social behavior in adult mice

Presenter : Tin-Tin-Win-Shwe, Chaw Kyi Tha Thu, Yadanar Moe, Fujitani Y., Tsukahara S, Watanabe H., Hirano S.
Name of Society : 8th Federation of the Asian and Oceanian Physiological Society Congress (2015)
Name of Proceedings : Abstracts, S-A178
Research Presentation
Comparison of redox activity of roadside and urban aerosols in Japan

Presenter : Fujitani Y., Furuyama A., Tanabe K., Hirano S.
Name of Society : JSPS-DFG Workshop on Aerosols Physicochemical Properties of Atmospheric Aerosols and their Effects on Air Quality and Public Health (2015)
Name of Proceedings : -
Research Presentation
Comparison of Redox Activity of Roadside and Urban Aerosols in Japan

Presenter : Fujitani Y., Furuyama A., Tanabe K., Hirano S.
Name of Society : Atmospheric Sciences and Application to Air Quality 13 (2015)
Name of Proceedings : Abstracts, 81
Research Presentation
Tissue distribution and excretion of arsenic and selenium following co-administration of arsenate and selenite in rats

Presenter : Kobayashi Y., Hirano S.
Name of Society : 17th BNASS / 14th TraceSpec (2014)
Name of Proceedings : Abstracts, 92
Research Presentation
Effects of developmental exposure to diesel engine exhaust origin secondary organic aerosol on social and learning behavior in adult mice

Presenter : Tin-Tin-Win-Shwe, Maekawa F., Chaw Kyi Tha Thu, Fujitani Y., Yanagisawa R., Furuyama A., Tsukahara S, Nohara K., Nitta H., Hirano S.
Name of Society : 37th Annual Meeting of the Japan Neuroscience Society (2014)
Name of Proceedings : Abstract, 131
Research Presentation
Developmental neurotoxicity of dendrimer nanoparticles: an in vitro study

Presenter : Kurokawa Y., Zeng Y., Zeng Q, Tin-Tin-Win-Shwe, Hirano S., Sone H.
Name of Society : 37th Annual Meeting of the Japan Neuroscience Society (2014)
Name of Proceedings : -
Research Presentation
Diesel engine exhaust origin secondary organic aerosol affects novel object recognition ability and maternal behavior in BALB/c mice

Presenter : Tin-Tin-Win-Shwe, Fujitani Y., Chaw Kyi ThaThu, Furuyama A., Shinji Tsukahara, Nitta H., Hirano S.
Name of Society : 8th International Congress of Neuroendocrinology 2014 (2014)
Name of Proceedings : Abstract, 31
Research Presentation
Particle deposition efficiency in air-liquid interface of a cell exposure chamber

Presenter : Fujitani Y., Sugaya Y., Hashiguchi M., Furuyama A., Hirano S., Takami A.
Name of Society : 2014 International Aerosol Conference (2014)
Name of Proceedings : Abstracts
Research Presentation
Toxicity of nanoparticles (NPs)-A comparative approach on the example of apatite particles

Presenter : Wozniak M.J., Oberbek P., Bolek T., Idaszek J., Puzyn T., Hirano S., Kurzydlowski K.J.
Name of Society : NIMS conference 2014 (2014)
Name of Proceedings : Abstracts, 110
Research Presentation
Cytotoxicity assessment of hydroxyapatite nanoparticles on BEAS-2B and A549 cell lines

Presenter : Bolek T., Hirano S., Wozniak M., Oberbek P., Kurzydlowski K.
Name of Society : NIMS conference 2014 (2014)
Name of Proceedings : Abstracts, 122
Research Presentation
The assessment of a toxicity of an active optical nanoparticles by in vitro test

Presenter : Cieslik I., Bolek T., Wozniak M, Hirano S.
Name of Society : NIMS Conference 2014 (2014)
Name of Proceedings : Abstracts, 145
Research Presentation
Tissue distribution and excretion of arsenic and selenium following co-administration of diphenylarsinic acid and selenite in rats

Presenter : Kobayashi Y., Hirano S.
Name of Society : 53rd Annual Meeting and ToxExpo (2014)
Name of Proceedings : -
Research Presentation
Metabolic Behavior and Effects of Ion and Nanoparticle Forms of Silver in the Mouse Lung and Macrophages

Presenter : Miyayama T., Arai Y., Hirano S.
Name of Society : 53rd Annual Meeting and ToxExpo (2014)
Name of Proceedings : Abstract, 212
Research Presentation
Biodistribution and toxicological effects of intranasally instilled polyamidoamine(PAMAM)dendrimers in BALB/c mouse brain

Presenter : Tin-Tin-Win-Shwe, Kurokawa Y., Nitta H., Hirano S., Sone H.
Name of Society : eurotox 2013 (2013)
Name of Proceedings : Toxicology Letters, 221S(28):S240
Research Presentation
A Role of Macrophage Receptor with Collagenous Structure (MARCO) in Cellular Uptake of Particulate Substances

Presenter : Hirano S., S. Kanno
Name of Society : 13 International Congress of Toxicology (2013)
Name of Proceedings : Abstracts, 46
Research Presentation
Instability of metallothionein inhibits mitochondrial activities following exposure to silver nitrate in human bronchial epithelial cells

Presenter : Miyayama T. , Arai Y., Suzuki N., Hirano S.
Name of Society : 52nd annual meeting and ToxExpo: Society of Toxicology 2013 (2013)
Name of Proceedings : Abstracts, 251
Research Presentation
Rho-Kinases Are Involved in Caspase-1-Mediated IL-1β Secretion following In Vitro Exposure to Multiwalled Carbon Nanotubes and Asbestos in Human Monocyte.

Presenter : Kanno S., Hirano S., Chiba S., Takeshita H., Nagai T., Takeda M., Mukai T.
Name of Society : 52nd annual meeting of Society of Toxicology. (2013)
Name of Proceedings : The Toxicologists, 95
Research Presentation
Elucidation of the metabolic pathways of arsenic by hyphenated analytical techniques.

Presenter : Kobayashi Y., Hirano S.
Name of Society : NIES Arsenic Workshop 2013 (2013)
Name of Proceedings : Abstracts, 20
Research Presentation
Implication of relationship between arsenic toxicity and arsenic metabolites

Presenter : Kobayashi Y., Mizumura A., Yamashiro A., Hirano S.
Name of Society : 10 ISTERH 2013 (2013)
Name of Proceedings : Journal of Trace Elements in Medicine and Biology, 27(S1):12
Research Presentation
Determination of nanoparticle deposition efficiency in the air-liquid interface cell exposure system

Presenter : Fujitani Y., Sugaya Y., Hashiguchi M., Furuyama A., Hirano S., Takami A.
Name of Society : 6th International Symposium on Nanotechnology, Occupational and Environmental Health (2013)
Name of Proceedings : Abstracts, 91-91
Research Presentation
Pulmonary and extrapulmonary responses to acute inhalation of multi-walled carbon nanotubes in mice

Presenter : Furuyama A., Fujitani Y., Hirano S.
Name of Society : 6th International Symposium on Nanotechnology, Occupational and Environmental Health (2013)
Name of Proceedings : Abstracts, 14
Research Presentation
Intracellular distribution of PAMAM dendrimers in cultured human cells

Presenter : Kurokawa Y., Tin-Tin-Win-Shwe, Zeng Q, Hirano S., Sone H.
Name of Society : 6th International Symposium on Nanotechnology, Occupational and Environmental Health (NanOEH) (2013)
Name of Proceedings : Abstracts, 89
Research Presentation
Cellular distribution of AgNPs and behavior of metallothionein in human bronchial epithelial cells

Presenter : Miyayama T. , Arai Y., Hirano S.
Name of Society : 6th International Symposium on Nanotechnology, Occupational and Environmental Health (NanOEH) (2013)
Name of Proceedings : Abstract, 102
Research Lecture
Inhalation study and Respiratory Toxicology.

Presenter : Hirano S.
Name of Society : 6th International Symposium on Nanotechnology, Occupational and Environmental Health (NanOEH) (2013)
Name of Proceedings : -
Research Presentation
In vivo and in vitro biological effects and biodistribution of PAMAM-NH2 dendrimers

Presenter : Tin-Tin-Win-Shwe, Kurokawa Y., Zeng Y., Nitta H., Hirano S., Sone H.
Name of Society : 6th International Symposium on Nanotechnology,Occupational and Environmental Health (2013)
Name of Proceedings : Abstracts, 31
Research Presentation
Effect of PAMAM dendrimers on differentiation of hNPCs: A study of morphological analysis

Presenter : Zeng Y., Tin-Tin-Win-Shwe, Zeng Q, Kurokawa Y., Hirano S., ZHANG.A.Y, Sone H.
Name of Society : 6th International Symposium on Nanotechnology,Occupational and Environmental Health (2013)
Name of Proceedings : Abstracts
Research Presentation
Determinations of PAMAM particles in culture media using SPM techniques

Presenter : Sone H., Yamazaki M., Zaha H., Zeng Y., Kurokawa Y., Tin-Tin-Win-Shwe, Hirano S.
Name of Society : 6th International Symposium on Nanotechnology, Occupational and Environmental Health (NanOEH) (2013)
Name of Proceedings : -
Research Presentation
Behavior Analysis of Titanium Dioxide Nanoparticles in Water and Consideration of Exposing Test Conditions for Aquatic Organisms

Presenter : Nakamura A., Yamamuro M., Hirano S., Tatarazako N.
Name of Society : SETAC Asia Pacific 2012 (2012)
Name of Proceedings : Abstracts, 143
Research Presentation
Determination of Measurement Conditions and Development of Analytical Methods for Use in Studying Nanoparticles in Water Using Dynamic Light Scattering.

Presenter : Nakamura A., Yamamuro M., Hirano S., Tatarazako N.
Name of Society : SETAC Asia Pacific 2012 (2012)
Name of Proceedings : Abstracts, 257
Research Presentation
Effects of arsenite on macropinocytotic and autophagic activities in CHO-K1 cells.

Presenter : Hirano S., Watanabe M., Kobayashi Y., Kanno S.
Name of Society : The 4th International Congress on Arsenic in the Environment. (2012)
Name of Proceedings : Understanding of the Geological and Medical Interface of Arsenic, 196-198
Research Presentation
Involvement of Rho-kinase in sulfide-induced apoptosis in Jurkat cells.

Presenter : Kanno S., Hirano S., Sagi M., Chiba S., Takeshita H., Iwata T., Chiba K., Mukai T.
Name of Society : The International Association of Forensic Toxicologists (TIAFT) 2012 (2012)
Name of Proceedings : Abstracts
Research Presentation
Cellular accumulation and behavior of silver and induction of metallothionein in human bronchial epithelial cells following exposure to silver nitrate

Presenter : Miyayama T. , Arai Y., Hirano S.
Name of Society : 51st annual meeting and ToxExpo: Society of Toxicology 2012 (2012)
Name of Proceedings : Abstracts, 2484
Research Presentation
Simultaneous Analysis of Cardiac Glycosides in Blood and Urine by Thermoresponsive LC-MS-MS

Presenter : Sanae Kanno, Toshiji Mukai, Hirano S., Osamu Suzuki
Name of Society : The International Association of Forensic Toxicologists 2011 (2011)
Name of Proceedings : Program and Abstracts of The International Association of Forensic Toxicologists 2011, P002
Research Presentation
Spatial and non-spatial learning performance in mice exposed to nanoparticle-rich diesel exhaust particles

Presenter : Tin-Tin-Win-Shwe, Kurokawa Y., Fujitani Y., Hirano S., Fujimaki H.
Name of Society : The 52nd Annual Meeting of Japan Society for Atmospheric Environment (2011)
Name of Proceedings : Abstracts of The 52nd Annual Meeting of Japan Society for Atmospheric Environment, 293
Research Presentation
Hippocampus-dependent spatial learning deficit in mice following sub-chronic exposure to nanoparticle-rich diesel exhaust

Presenter : Tin-Tin-Win-Shwe, Fujitani Y., Hirano S., Fujimaki H.
Name of Society : Eurotox2011 PARIS (2011)
Name of Proceedings : Program of Eurotox2011 PARIS, 124
Research Presentation
Distribution and biliary excretion of arsenic in rats orally administered with dipheneylarsinic acid

Presenter : Kobayashi Y., Yamashiro A, Hirano S.
Name of Society : Metallomics 2011 3rd International Symposium on Metallomics (2011)
Name of Proceedings : Poster Session of Metallomics 2011 3rd International Symposium on Metallomics
Research Presentation
Distribution and excretion of arsenicals following a single oral administration of organic arsenic compounds in rats.

Presenter : Kobayashi Y., Mizumura A., Yamashiro A, Hirano S.
Name of Society : 4th International IUPAC Symposium for Trace Elements in Food (2011)
Name of Proceedings : Abstracts of 4th International IUPAC Symposium for Trace Elements in Food, 69
Research Lecture
Responses of pulmonary cells to carbon nanotubes

Presenter : Hirano S., Furuyama A.
Name of Society : 10th Int.Cof.Int.Mesothelioma Interest Group(MIG2010) (2010)
Name of Proceedings : Abstracts, 91
Research Presentation
Uptake and effects of carbon nanotubes in bronchial epithelial cells

Presenter : Hirano S., Furuyama A., Fujitani Y.
Name of Society : 12th Int.Congr.Toxicol. (2010)
Name of Proceedings : Program, 79
Research Lecture
Cellular uptake of nanoparticles via macrophage receptor with collagenous structure

Presenter : Hirano S.
Name of Society : Int.Symp.Occup.Environ.Allerg.Immune Dis.2010(ISOEAID’10) (2010)
Name of Proceedings : Abstracts, 30
Research Presentation
A multidisciplinary group for an improvement of nanorisk assessment and management

Presenter : Claude. E, Christian. R, Hirano S., Frederic. S, Stephane. H
Name of Society : Nanosafe 2010 (2010)
Name of Proceedings : -
Research Presentation
Differential proteomic study of exposed cells to SiC and SWCNT nanoparticles

Presenter : Tokarski C., Hirano S., Chistian R.
Name of Society : Nanosafe 2010 (2010)
Name of Proceedings : ー
Research Presentation
Exposure of mammalian cells to carbon nanotubes. How do the cells react to the fiber in vitro?

Presenter : Hirano S., Furuyama A., Fujitani Y., Kanno S.
Name of Society : 4th Int.Conf.Environ.Eff.Nanopart.Nanomater. (2009)
Name of Proceedings : Abstracts
Research Presentation
Analysis of neurotoxic effect of nanoparticle-rich diesel exhaust on a mouse brain

Presenter : Yamamoto S., Tin-Tin-Win-Shwe, Mitsushima D., Fujitani Y., Hirano S., Fujimaki H.
Name of Society : 13th Congr.Eur.Fed.Neurol.Soc. (2009)
Name of Proceedings : Abstracts, 325
Research Presentation
Targeting in nanoparticle-induced neurotoxicity in mice

Presenter : Tin-Tin-Win-Shwe, Yamamoto S., Fujitani Y., Hirano S., Fujimaki H.
Name of Society : 79th Annu.Meet.Jpn.Soc.Hygiene(第79回日本衛生学会学術総会) (2009)
Name of Proceedings : Jpn.J.Hyg.(日衛誌）, 64(2):291
Research Presentation
Analysis of spatial learning performance and memory function-related gene expressions in the hippocampus of mice exposed to nanoparticle-rich diesel exhaust

Presenter : Tin-Tin-Win-Shwe, Yamamoto S., Fujitani Y., Hirano S., Fujimaki H.
Name of Society : 31st Annu.Meet.Jpn.Neurosci.Soc. (2008)
Name of Proceedings : Neurosci.Res., 61(Suppl.1):S258
Research Presentation
Effects of glutathione and hydrogen peroxide on stability of biliary metabolites,arsenic triglutathione and methylarsenic diglutathione,in rat bile

Presenter : HIRANO Seishiro
Name of Society : 47th Annu.Meet.ToxExpo(Poster Session) (2008)
Name of Proceedings : Abstracts(CD-ROM)
Research Presentation
Neurotoxic effect of nanoparticle-rich diesel exhaust in the mouse olfactory bulb

Presenter : Tin-Tin-Win-Shwe, Mitsushima D., Yamamoto S., Fujitani Y., Funabashi T., Hirano S., Fujimaki H.
Name of Society : 45th Congr.Eur.Soc.Toxicol. (2008)
Name of Proceedings : Toxicol.Lett., 180S(2008):S206
Research Presentation
Gene expression signatures of environmental chemicals in cancer and developmental disorders

Presenter : Sone H., Hirano S., Nagano R., Akanuma h., Imanishi S., Fukuda T., Osako S.
Name of Society : 14th Biennial Meet.Soc.Free Radical Res.Int.(SFRRI 2008) (2008)
Name of Proceedings : Abstracts, 35(Suppl.):109-110
Research Presentation
Effects of diesel exhaust particles with high concentration nanoparticles on cardiovascular system

Presenter : Suzuki A.K., Taneda S., Fujitani Y., Li C., Hirano S.
Name of Society : Int.Workshop Environ.Nanoparticles-Spec.Ref.Atmos.Environ.- (2008)
Name of Proceedings : Abstracts
Research Presentation
Central nervous effect of organoarsinic compound clinical and neurological features of diphenylarsinic asid(DPAA) intoxication,in Kamisu,Japan

Presenter : , HIRANO Seishiro
Name of Society : 27th Int.Symp.Halogenat.Persistent.Org.Pollut.-DIOXIN 2007 (2007)
Name of Proceedings : Organohalogen Compd.
Research Presentation
Carbon nanotubes injure the plasma membrane of macrophages

Presenter : Hirano S., Kanno S., Furuyama A.
Name of Society : 11th Int.Congr.Toxicol.(Poster Session) (2007)
Research Presentation
Metabolic pathway of arsenic based on analytical toxicology

Presenter : HIRANO Seishiro
Name of Society : 17th Annu.Meet.Jpn.Soc.Biomed.Res.Trace Elem.(BRTE2006) (2006)
Name of Proceedings : Biomed.Res.Trace Elem., 17(2)
Research Presentation
Temporal and spatial variations in the seasonal patterns of CO2 flux in boreal,temperate,and tropical forests in Asia

Presenter : HIRANO Seishiro
Name of Society : AsiaFlux Workshop 2006 (2006)
Name of Proceedings : Abstracts
Research Presentation
Reactivation of p16INK4a and RASSF1A genes and inhibition of c-myc and htert expression by As203 in colorectal cancer cells

Presenter : HIRANO Seishiro
Name of Society : 20th Eur.Congr.Pathol. (2005)
Name of Proceedings : Abstracts
Research Presentation
A study on the transport of nanoparticles through an in vitro alveolo-capillary barrier model

Presenter : Furuyama A., Kanno S., Hirano S.
Name of Society : 58th Annu.Meet.Jpn.Soc.Cell Biol.(Poster Session） (2005)
Name of Proceedings : Cell Structure and Function, 30
Research Presentation
Arsenic methyltransferase Cyt19 expression and activity in rat tissues.

Presenter : HIRANO Seishiro
Name of Society : Soc.Toxicol.44th Annu.Meet. (2005)
Name of Proceedings : Abstracts
Research Presentation
Effect of arsenite on PU.1,C/EBPS,and NFKB activation in U937 promonocytic leukemia cells

Presenter : Yamamoto M., Hirano S., Jefcoate C.R.(*1), Matsumura F.(*2)
Name of Society : Soc.Toxicol.44th Annu.Meet. (2005)
Name of Proceedings : Abstracts
Research Presentation
A Study on the transport of nanopartocles through an in vitro alveolo-capillary model

Presenter : Furuyama A., Kanno S., Hirano S.
Name of Society : Mechanisms of Action of Inhaled Fibers,Particles,and Nanoparticles in Lung and Cardiovascular Disease(Poster Session） (2005)
Name of Proceedings : Abstracts
Research Presentation
Size-dependent uptake of particles through scavenger receptor MARCO

Presenter : Kanno S., Furuyama A., Hirano S.
Name of Society : Mech.Action.Inhaled Fibers,Particles,Nanoparticles Lung Cardiovascular Disease (2005)
Name of Proceedings : Abstracts
Research Presentation
Effects of glutathione on accumulation and toxicity of arsenicals in rat endothelial cells

Presenter : HIRANO Seishiro
Name of Society : 10th Int.Congr.Toxicol. (2004)
Name of Proceedings : Abstracts
Research Presentation
Effect of arsenite on PU.1,C/EBPs,and NFkB activation in U937 promonocytic leukemia cells

Presenter : HIRANO Seishiro
Name of Society : 77th Annu.Meet.Jpn.Biochem.Soc. (2004)
Name of Proceedings : Seikagaku, 76(8)
Research Presentation
Basement membrane attenuates oxidative stress caused by organic extracts of diesel exhaust particles in rat lung microvessel endothelial cells

Presenter : Hirano S., Mochitate K., Furuyama A., Koike E.
Name of Society : 5th Pan Pac.Connect.Tissue Soc.Symp. (2003)
Name of Proceedings : Abstracts, 82
Research Presentation
Interleukin 1-beta and tumor necrosis factor-alpha suppressed basement membrane formation by alveolar epithelial cells cultured with fibroblasts

Presenter : Hirano S., Mochitate K., Furuyama A.
Name of Society : 11th Int.Sym.Basement Membranes (2003)
Name of Proceedings : Abstracts, 4
Research Presentation
Demethylation of CpG islands and reactivation of tumor suppressor genes induced by arsenic in HepG2 cells

Presenter : HIRANO Seishiro
Name of Society : 11th United Eur.Gastroentelogy Week (2003)
Name of Proceedings : Abstracts, A121
Research Presentation
Organic extracts of diesel exhaust particles stimulate collagen production in rat pulmonary fibroblasts in vitro

Presenter : Hirano S., Mochitate K., Furuyama A.
Name of Society : 76th Annu.Meet.Jpn.Biochem.Soc. (2003)
Name of Proceedings : Seikagaku, 75(8)(8):1123
Research Presentation
Sodium arsenate suppresses beta-catenin and pten expression in liver

Presenter : HIRANO Seishiro
Name of Society : 5th Int.Conf.Aresenic Exposure Health Eff. (2002)
Name of Proceedings : Abstracts, 167
Research Presentation
Uptake of arsenics and oxidative stress in endothelial cells

Presenter : HIRANO Seishiro
Name of Society : Am./Jpn.Conf.Arsenic Med.Biol.11th/15th (2002)
Name of Proceedings : Abstracts, 27
Extraction and speciation of arsenic hair

Presenter : Hirano S.
Name of Society : Int.Congr.Anal.Sci.2001 (2001)
Name of Proceedings : Abstracts
Analysis of organic arsenic species in tube-well water of West Bengal-India

Presenter : Hirano S.
Name of Society : 5th Int.Conf.Environ.& Biol.Aspects Main-Grop Organomet. (2001)
Name of Proceedings : ICEBAMO
Oxidative damage to mitochondria is a preliminary step to caspase-3 activation in fluoride-induced apoptosis in HL-60 cells

Presenter : Anuradha C.D., Kanno S., Hirano S.
Name of Society : Soc.Toxicol. (2001)
Name of Proceedings : Abstracts, 60(1)
Sodium arsenate induced alterations of cyclin D1,p27 and ILK expression in rat liver

Presenter : Hirano S.
Name of Society : 10th Int.Symp.Nat.Ind.Arsenic Jpn. (2001)
Name of Proceedings : Abstracts

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Evaluation of neurotoxicity by air pollutant exposure using animal model

Presenter : Tin-Tin-Win-Shwe, Fujitani Y., Hirano S.
Name of Society : 44th Annual Meeting of the Japan Society of Toxicology (2017)
Name of Proceedings : Abstracts, S90
Establishment of an olfactory-based spatial learning test for neonatal mice and the effects of perinatal exposure to diesel exhaust origin secondary organic aerosol

Presenter : Tin-Tin-Win-Shwe, Tha-Thu C.K., Moe Y., Fujitani Y., Tsukahara S., Hirano S.
Name of Society : 11th International Particle Toxicology Conference (2016)
Name of Proceedings : Abstract, 54
Impact on the learning ability and neuro-immune biomarkers by diesel exhaust originated secondary organic aerosol exposure ディーゼル排気ガス由来二次有機エアロゾル曝露による学習能力と神経免疫バイオマーカーへの影響

Presenter : Tin-Tin-Win-Shwe, Fujitani Y., Hirano S.
Name of Society : 39th Annual Meeting of the Molecular Biology Society of Japan (2016)
Name of Proceedings : Abstarct, 137
Comparison of redox activity of roadside and urban aerosols in Japan

Presenter : Fujitani Y., Furuyama A., Tanabe K., Hirano S.
Name of Society : JSPS-DFG Workshop on Aerosols Physicochemical Properties of Atmospheric Aerosols and their Effects on Air Quality and Public Health (2015)
Name of Proceedings : -
Comparison of Redox Activity of Roadside and Urban Aerosols in Japan

Presenter : Fujitani Y., Furuyama A., Tanabe K., Hirano S.
Name of Society : Atmospheric Sciences and Application to Air Quality 13 (2015)
Name of Proceedings : Abstracts, 81
A Role of Macrophage Receptor with Collagenous Structure (MARCO) in Cellular Uptake of Particulate Substances

Presenter : Hirano S., S. Kanno
Name of Society : 13 International Congress of Toxicology (2013)
Name of Proceedings : Abstracts, 46
Elucidation of the metabolic pathways of arsenic by hyphenated analytical techniques.

Presenter : Kobayashi Y., Hirano S.
Name of Society : NIES Arsenic Workshop 2013 (2013)
Name of Proceedings : Abstracts, 20
Implication of relationship between arsenic toxicity and arsenic metabolites

Presenter : Kobayashi Y., Mizumura A., Yamashiro A., Hirano S.
Name of Society : 10 ISTERH 2013 (2013)
Name of Proceedings : Journal of Trace Elements in Medicine and Biology, 27(S1):12
Pulmonary and extrapulmonary responses to acute inhalation of multi-walled carbon nanotubes in mice

Presenter : Furuyama A., Fujitani Y., Hirano S.
Name of Society : 6th International Symposium on Nanotechnology, Occupational and Environmental Health (2013)
Name of Proceedings : Abstracts, 14
Behavior Analysis of Titanium Dioxide Nanoparticles in Water and Consideration of Exposing Test Conditions for Aquatic Organisms

Presenter : Nakamura A., Yamamuro M., Hirano S., Tatarazako N.
Name of Society : SETAC Asia Pacific 2012 (2012)
Name of Proceedings : Abstracts, 143
Effects of arsenite on macropinocytotic and autophagic activities in CHO-K1 cells.

Presenter : Hirano S., Watanabe M., Kobayashi Y., Kanno S.
Name of Society : The 4th International Congress on Arsenic in the Environment. (2012)
Name of Proceedings : Understanding of the Geological and Medical Interface of Arsenic, 196-198
Simultaneous Analysis of Cardiac Glycosides in Blood and Urine by Thermoresponsive LC-MS-MS

Presenter : Sanae Kanno, Toshiji Mukai, Hirano S., Osamu Suzuki
Name of Society : The International Association of Forensic Toxicologists 2011 (2011)
Name of Proceedings : Program and Abstracts of The International Association of Forensic Toxicologists 2011, P002
Spatial and non-spatial learning performance in mice exposed to nanoparticle-rich diesel exhaust particles

Presenter : Tin-Tin-Win-Shwe, Kurokawa Y., Fujitani Y., Hirano S., Fujimaki H.
Name of Society : The 52nd Annual Meeting of Japan Society for Atmospheric Environment (2011)
Name of Proceedings : Abstracts of The 52nd Annual Meeting of Japan Society for Atmospheric Environment, 293
A multidisciplinary group for an improvement of nanorisk assessment and management

Presenter : Claude. E, Christian. R, Hirano S., Frederic. S, Stephane. H
Name of Society : Nanosafe 2010 (2010)
Name of Proceedings : -
Differential proteomic study of exposed cells to SiC and SWCNT nanoparticles

Presenter : Tokarski C., Hirano S., Chistian R.
Name of Society : Nanosafe 2010 (2010)
Name of Proceedings : ー
Targeting in nanoparticle-induced neurotoxicity in mice

Presenter : Tin-Tin-Win-Shwe, Yamamoto S., Fujitani Y., Hirano S., Fujimaki H.
Name of Society : 79th Annu.Meet.Jpn.Soc.Hygiene(第79回日本衛生学会学術総会) (2009)
Name of Proceedings : Jpn.J.Hyg.(日衛誌）, 64(2):291
Effects of glutathione and hydrogen peroxide on stability of biliary metabolites,arsenic triglutathione and methylarsenic diglutathione,in rat bile

Presenter : HIRANO Seishiro
Name of Society : 47th Annu.Meet.ToxExpo(Poster Session) (2008)
Name of Proceedings : Abstracts(CD-ROM)
Gene expression signatures of environmental chemicals in cancer and developmental disorders

Presenter : Sone H., Hirano S., Nagano R., Akanuma h., Imanishi S., Fukuda T., Osako S.
Name of Society : 14th Biennial Meet.Soc.Free Radical Res.Int.(SFRRI 2008) (2008)
Name of Proceedings : Abstracts, 35(Suppl.):109-110
Effects of diesel exhaust particles with high concentration nanoparticles on cardiovascular system

Presenter : Suzuki A.K., Taneda S., Fujitani Y., Li C., Hirano S.
Name of Society : Int.Workshop Environ.Nanoparticles-Spec.Ref.Atmos.Environ.- (2008)
Name of Proceedings : Abstracts
Central nervous effect of organoarsinic compound clinical and neurological features of diphenylarsinic asid(DPAA) intoxication,in Kamisu,Japan

Presenter : , HIRANO Seishiro
Name of Society : 27th Int.Symp.Halogenat.Persistent.Org.Pollut.-DIOXIN 2007 (2007)
Name of Proceedings : Organohalogen Compd.
Carbon nanotubes injure the plasma membrane of macrophages

Presenter : Hirano S., Kanno S., Furuyama A.
Name of Society : 11th Int.Congr.Toxicol.(Poster Session) (2007)
Metabolic pathway of arsenic based on analytical toxicology

Presenter : HIRANO Seishiro
Name of Society : 17th Annu.Meet.Jpn.Soc.Biomed.Res.Trace Elem.(BRTE2006) (2006)
Name of Proceedings : Biomed.Res.Trace Elem., 17(2)
Temporal and spatial variations in the seasonal patterns of CO2 flux in boreal,temperate,and tropical forests in Asia

Presenter : HIRANO Seishiro
Name of Society : AsiaFlux Workshop 2006 (2006)
Name of Proceedings : Abstracts
Reactivation of p16INK4a and RASSF1A genes and inhibition of c-myc and htert expression by As203 in colorectal cancer cells

Presenter : HIRANO Seishiro
Name of Society : 20th Eur.Congr.Pathol. (2005)
Name of Proceedings : Abstracts
A study on the transport of nanoparticles through an in vitro alveolo-capillary barrier model

Presenter : Furuyama A., Kanno S., Hirano S.
Name of Society : 58th Annu.Meet.Jpn.Soc.Cell Biol.(Poster Session） (2005)
Name of Proceedings : Cell Structure and Function, 30
Arsenic methyltransferase Cyt19 expression and activity in rat tissues.

Presenter : HIRANO Seishiro
Name of Society : Soc.Toxicol.44th Annu.Meet. (2005)
Name of Proceedings : Abstracts
Effect of arsenite on PU.1,C/EBPS,and NFKB activation in U937 promonocytic leukemia cells

Presenter : Yamamoto M., Hirano S., Jefcoate C.R.(*1), Matsumura F.(*2)
Name of Society : Soc.Toxicol.44th Annu.Meet. (2005)
Name of Proceedings : Abstracts
A Study on the transport of nanopartocles through an in vitro alveolo-capillary model

Presenter : Furuyama A., Kanno S., Hirano S.
Name of Society : Mechanisms of Action of Inhaled Fibers,Particles,and Nanoparticles in Lung and Cardiovascular Disease(Poster Session） (2005)
Name of Proceedings : Abstracts
Size-dependent uptake of particles through scavenger receptor MARCO

Presenter : Kanno S., Furuyama A., Hirano S.
Name of Society : Mech.Action.Inhaled Fibers,Particles,Nanoparticles Lung Cardiovascular Disease (2005)
Name of Proceedings : Abstracts
Effects of glutathione on accumulation and toxicity of arsenicals in rat endothelial cells

Presenter : HIRANO Seishiro
Name of Society : 10th Int.Congr.Toxicol. (2004)
Name of Proceedings : Abstracts
Effect of arsenite on PU.1,C/EBPs,and NFkB activation in U937 promonocytic leukemia cells

Presenter : HIRANO Seishiro
Name of Society : 77th Annu.Meet.Jpn.Biochem.Soc. (2004)
Name of Proceedings : Seikagaku, 76(8)
Basement membrane attenuates oxidative stress caused by organic extracts of diesel exhaust particles in rat lung microvessel endothelial cells

Presenter : Hirano S., Mochitate K., Furuyama A., Koike E.
Name of Society : 5th Pan Pac.Connect.Tissue Soc.Symp. (2003)
Name of Proceedings : Abstracts, 82
Interleukin 1-beta and tumor necrosis factor-alpha suppressed basement membrane formation by alveolar epithelial cells cultured with fibroblasts

Presenter : Hirano S., Mochitate K., Furuyama A.
Name of Society : 11th Int.Sym.Basement Membranes (2003)
Name of Proceedings : Abstracts, 4
Demethylation of CpG islands and reactivation of tumor suppressor genes induced by arsenic in HepG2 cells

Presenter : HIRANO Seishiro
Name of Society : 11th United Eur.Gastroentelogy Week (2003)
Name of Proceedings : Abstracts, A121
Organic extracts of diesel exhaust particles stimulate collagen production in rat pulmonary fibroblasts in vitro

Presenter : Hirano S., Mochitate K., Furuyama A.
Name of Society : 76th Annu.Meet.Jpn.Biochem.Soc. (2003)
Name of Proceedings : Seikagaku, 75(8)(8):1123
Sodium arsenate suppresses beta-catenin and pten expression in liver

Presenter : HIRANO Seishiro
Name of Society : 5th Int.Conf.Aresenic Exposure Health Eff. (2002)
Name of Proceedings : Abstracts, 167
Uptake of arsenics and oxidative stress in endothelial cells

Presenter : HIRANO Seishiro
Name of Society : Am./Jpn.Conf.Arsenic Med.Biol.11th/15th (2002)
Name of Proceedings : Abstracts, 27
Perinatal diesel exhaust originated secondary organic aerosol exposure produces autism-like behaviors in offspring rats: comparison with valproic acid autistic model

Presenter : Tin-Tin-Win-Shwe, Fujitani Y., Hirano S.
Name of Society : 43rd Annual Meeting of the japan Neuroscience Society (2020)
Name of Proceedings : Abstract (P2-231)
Effects of selenite on uptake of arsenite in rat erythrocytes

Presenter : Kobayashi Y., Suzuki N., Ogra Y., Hirano S.
Name of Society : The 18th International Conference of the Pacific Basin Consortium for Environment and Health (2019)
Name of Proceedings : -
Alteration of social dominance behavior in rats after developmental exposure to secondary organic aerosol

Presenter : Tin-Tin-Win-Shwe, Fujitani Y., Hirano S.
Name of Society : The 42nd Annual Meeting of the Japan Neuroscience Society (2019)
Name of Proceedings : Abstract, 281
Distribution, metabolism and excretion of arsenolipids in mice after oral administration.

Presenter : Kobayashi Y., Suzuki N., Ogra Y., Hirano S.
Name of Society : IUTOX 15th InternationalCongress of Toxicology (2019)
Name of Proceedings : Abstract, 164
Developmental exposure to diesel exhaust-derived secondary organic aerosol (DE-SOA) on anxiety and depression in mice

Presenter : Tin-Tin-Win-Shwe, Fujitani Y., Hirano S.
Name of Society : 28th Symposium on Environmental Chemistry (2019)
Name of Proceedings : Abstract (Poster-134)
Social dominance behavior and brain biomarkers after gestational and lactational exposure to secondary organic aerosol in male rats

Presenter : Tin-Tin-Win-Shwe, Fujitani Y., Hirano S.
Name of Society : 47th Myanmar Health Research Congress (2019)
Name of Proceedings : Abstract, 130
Exposure assessment of barium sulfate particles in a factory

Presenter : Ichihara G., Huang Z., Ichihara S., Fujitani Y., Hirano S., Takeuchi S., Hirano A., Huang H.
Name of Society : NanoTox 2018 - 9th International Conference on Nanotoxicology (2018)
Name of Proceedings : Abstracts
Study of toxicology in an active optical nanocrystals

Presenter : Cieslik I., Kurpaska L., Budzianowski A., Hirano S.
Name of Society : 13th International Conference on Surfaces, Coatings and Nanostructured Materials (2018)
Name of Proceedings : NANOSMAT 2018 Abstracts, 18
Perinatal exposure to secondary organic aerosol influences neurobehavioral development and inflammatory markers in rats

Presenter : Tin-Tin-Win-Shwe, Fujitani Y., Hirano S.
Name of Society : 54th European Societies of Toxicology Meeting (EUROTOX2018) (2018)
Name of Proceedings : Abstract, 133
Developmental exposure to secondary organic aerosol alters social dominance behavior and expression of neuroimmune biomarkers in rats

Presenter : Tin-Tin-Win-Shwe, Nway N.C., Mar O., Watanabe H., Fujitani Y., Hirano S.
Name of Society : The 27th Symposium of Japan Environmental Chemistry (2018)
Name of Proceedings : Abstract, 536-537
Effects of cationic disinfectants on surface activity of pulmonary surfactant monolayers

Presenter : Kanno S., Hirano S., Mukai T., Kato H., Aoki Y.
Name of Society : The 57st Annual Meeting of the Society of Toxicology (2018)
Name of Proceedings : Abstract, 252
Developmental exposure to diesel exhaust origin secondary organic aerosol and role of TLR4 in olfactory-based spatial learning activity of neonatal mice

Presenter : Nway N.C., Fujitani Y., Mar O., Hirano S., Tin-Tin-Win-Shwe
Name of Society : 46th Myanmar Health Research Congress (2018)
Name of Proceedings : Abstract (Poster 21), 119
Distribution and excretion of arsenic in mice after oral administration of arsenolipid

Presenter : Kobayashi Y., Suzuki N., Ogra Y., Hirano S.
Name of Society : The 6th International Symposium on Metallomics (2017)
Name of Proceedings : -
Effects of diesel exhaust-derived secondary organic aerosol (SOA) on oocytes in mice

Presenter : Udagawa O., Furuyama A., Imai K., Fujitani Y., Hirano S.
Name of Society : 2017 Advanced Investigation in Mechanistic Toxicology, Gordon Research Conference (2017)
Name of Proceedings : Abstracts, 13
Role of toll-like receptor 4 in diesel exhaust origin secondary organic aerosol-induced impaired spatial learning ability in neonatal mice

Presenter : Tin-Tin-Win-Shwe, Fujitani Y., Watanabe H., Hirano S.
Name of Society : Society for Neuroscience 2016 (2016)
Name of Proceedings : Abstract, 61
Distribution and speciation of arsenic in mice intravenously injected with S-dimethylarsino-glutathione

Presenter : KATO A., Kobayashi Y., Udagawa O., Hirano S.
Name of Society : 44th Myanmar health research congress (2016)
Name of Proceedings : Abstracts, 97-98
Novel approach to olfactory-based spatial learning ability for preweaning mice and the effects of early exposure to diesel exhaust origin secondary organic aerosol

Presenter : Tin-Tin-Win-Shwe, Chaw Kyi Tha Thu, Yadanar Moe, Fujitani Y., Shinji Tsukahara, Maekawa F., Hirano S.
Name of Society : 44th Myanmar Health Research Congress (2016)
Name of Proceedings : Abstract, 79
Enhanced particle deposition efficiency in air-liquid interface of a cell exposure chamber by electrostatic force

Presenter : Fujitani Y., Sugaya Y., Hashiguchi M., Furuyama A., Hirano S., Takami A.
Name of Society : The 2015 European Aerosol Conference (2015)
Name of Proceedings : Abstract
Establishment of an olfactory-based spatial learning test for preweaning mice and the ef-fects of early exposure to diesel exhaust origin secondary organic aerosol

Presenter : Tin-Tin-Win-Shwe, Chaw Kyi-Tha Thu, Yadanar Moe, Fujitani Y., Shinji Tsukahara, Nitta H., Hirano S.
Name of Society : 51st Congress of the European Societies of Toxicology (2015)
Name of Proceedings : Abstract, 120
Diesel engine exhaust origin secondary organic aerosol affects olfactory-based spatial learning performance and related gene expressions in preweaning mice

Presenter : Tin-Tin-Win-Shwe, Fujitani Y., Nohara K., Hirano S.
Name of Society : 第4回日本DOHaD研究会学術集会 (2015)
Name of Proceedings : Abtract, 115
Arsenic toxicity on female reproduction in mice; molecular examination on how oocyte quality contributes.

Presenter : Udagawa O., KATO A., Kobayashi Y., Aoki Y., Hirano S.
Name of Society : 2015 Cellular & Molecular Mechanisms of Toxicity Gordon Research Conference (2015)
Name of Proceedings : Abstracts, 16
Developmental exposure to diesel engine exhaust origin secondary organic aerosol on olfactory-based spatial learning performance in preweaning mice

Presenter : Tin-Tin-Win-Shwe, Fujitani Y., Furuyama A., Nitta H., Hirano S.
Name of Society : 第38回日本神経科学大会 (2015)
Name of Proceedings : Abstract(3P292), 250
Transport of adnlinistered dendrimer nanoparticles to neura:tissue:in vitro and in vivo studies

Presenter : Kurokawa Y., Zeng Y., Tin-Tin-Win-Shwe, Kimura H, Koyama Y, Matsui Y, Hirano S., Sone H.
Name of Society : 第38回日本神経科学大会(The 38th Annual Meeting of the Japan Neuroscience Society) (2015)
Name of Proceedings : Abstracts
Developmental exposure to diesel engine exhaust origin secondary organic aerosol on social behavior in adult mice

Presenter : Tin-Tin-Win-Shwe, Chaw Kyi Tha Thu, Yadanar Moe, Fujitani Y., Tsukahara S, Watanabe H., Hirano S.
Name of Society : 8th Federation of the Asian and Oceanian Physiological Society Congress (2015)
Name of Proceedings : Abstracts, S-A178
Tissue distribution and excretion of arsenic and selenium following co-administration of arsenate and selenite in rats

Presenter : Kobayashi Y., Hirano S.
Name of Society : 17th BNASS / 14th TraceSpec (2014)
Name of Proceedings : Abstracts, 92
Effects of developmental exposure to diesel engine exhaust origin secondary organic aerosol on social and learning behavior in adult mice

Presenter : Tin-Tin-Win-Shwe, Maekawa F., Chaw Kyi Tha Thu, Fujitani Y., Yanagisawa R., Furuyama A., Tsukahara S, Nohara K., Nitta H., Hirano S.
Name of Society : 37th Annual Meeting of the Japan Neuroscience Society (2014)
Name of Proceedings : Abstract, 131
Developmental neurotoxicity of dendrimer nanoparticles: an in vitro study

Presenter : Kurokawa Y., Zeng Y., Zeng Q, Tin-Tin-Win-Shwe, Hirano S., Sone H.
Name of Society : 37th Annual Meeting of the Japan Neuroscience Society (2014)
Name of Proceedings : -
Diesel engine exhaust origin secondary organic aerosol affects novel object recognition ability and maternal behavior in BALB/c mice

Presenter : Tin-Tin-Win-Shwe, Fujitani Y., Chaw Kyi ThaThu, Furuyama A., Shinji Tsukahara, Nitta H., Hirano S.
Name of Society : 8th International Congress of Neuroendocrinology 2014 (2014)
Name of Proceedings : Abstract, 31
Particle deposition efficiency in air-liquid interface of a cell exposure chamber

Presenter : Fujitani Y., Sugaya Y., Hashiguchi M., Furuyama A., Hirano S., Takami A.
Name of Society : 2014 International Aerosol Conference (2014)
Name of Proceedings : Abstracts
Toxicity of nanoparticles (NPs)-A comparative approach on the example of apatite particles

Presenter : Wozniak M.J., Oberbek P., Bolek T., Idaszek J., Puzyn T., Hirano S., Kurzydlowski K.J.
Name of Society : NIMS conference 2014 (2014)
Name of Proceedings : Abstracts, 110
Cytotoxicity assessment of hydroxyapatite nanoparticles on BEAS-2B and A549 cell lines

Presenter : Bolek T., Hirano S., Wozniak M., Oberbek P., Kurzydlowski K.
Name of Society : NIMS conference 2014 (2014)
Name of Proceedings : Abstracts, 122
The assessment of a toxicity of an active optical nanoparticles by in vitro test

Presenter : Cieslik I., Bolek T., Wozniak M, Hirano S.
Name of Society : NIMS Conference 2014 (2014)
Name of Proceedings : Abstracts, 145
Tissue distribution and excretion of arsenic and selenium following co-administration of diphenylarsinic acid and selenite in rats

Presenter : Kobayashi Y., Hirano S.
Name of Society : 53rd Annual Meeting and ToxExpo (2014)
Name of Proceedings : -
Metabolic Behavior and Effects of Ion and Nanoparticle Forms of Silver in the Mouse Lung and Macrophages

Presenter : Miyayama T., Arai Y., Hirano S.
Name of Society : 53rd Annual Meeting and ToxExpo (2014)
Name of Proceedings : Abstract, 212
Biodistribution and toxicological effects of intranasally instilled polyamidoamine(PAMAM)dendrimers in BALB/c mouse brain

Presenter : Tin-Tin-Win-Shwe, Kurokawa Y., Nitta H., Hirano S., Sone H.
Name of Society : eurotox 2013 (2013)
Name of Proceedings : Toxicology Letters, 221S(28):S240
Instability of metallothionein inhibits mitochondrial activities following exposure to silver nitrate in human bronchial epithelial cells

Presenter : Miyayama T. , Arai Y., Suzuki N., Hirano S.
Name of Society : 52nd annual meeting and ToxExpo: Society of Toxicology 2013 (2013)
Name of Proceedings : Abstracts, 251
Rho-Kinases Are Involved in Caspase-1-Mediated IL-1β Secretion following In Vitro Exposure to Multiwalled Carbon Nanotubes and Asbestos in Human Monocyte.

Presenter : Kanno S., Hirano S., Chiba S., Takeshita H., Nagai T., Takeda M., Mukai T.
Name of Society : 52nd annual meeting of Society of Toxicology. (2013)
Name of Proceedings : The Toxicologists, 95
Determination of nanoparticle deposition efficiency in the air-liquid interface cell exposure system

Presenter : Fujitani Y., Sugaya Y., Hashiguchi M., Furuyama A., Hirano S., Takami A.
Name of Society : 6th International Symposium on Nanotechnology, Occupational and Environmental Health (2013)
Name of Proceedings : Abstracts, 91-91
Intracellular distribution of PAMAM dendrimers in cultured human cells

Presenter : Kurokawa Y., Tin-Tin-Win-Shwe, Zeng Q, Hirano S., Sone H.
Name of Society : 6th International Symposium on Nanotechnology, Occupational and Environmental Health (NanOEH) (2013)
Name of Proceedings : Abstracts, 89
Cellular distribution of AgNPs and behavior of metallothionein in human bronchial epithelial cells

Presenter : Miyayama T. , Arai Y., Hirano S.
Name of Society : 6th International Symposium on Nanotechnology, Occupational and Environmental Health (NanOEH) (2013)
Name of Proceedings : Abstract, 102
In vivo and in vitro biological effects and biodistribution of PAMAM-NH2 dendrimers

Presenter : Tin-Tin-Win-Shwe, Kurokawa Y., Zeng Y., Nitta H., Hirano S., Sone H.
Name of Society : 6th International Symposium on Nanotechnology,Occupational and Environmental Health (2013)
Name of Proceedings : Abstracts, 31
Effect of PAMAM dendrimers on differentiation of hNPCs: A study of morphological analysis

Presenter : Zeng Y., Tin-Tin-Win-Shwe, Zeng Q, Kurokawa Y., Hirano S., ZHANG.A.Y, Sone H.
Name of Society : 6th International Symposium on Nanotechnology,Occupational and Environmental Health (2013)
Name of Proceedings : Abstracts
Determinations of PAMAM particles in culture media using SPM techniques

Presenter : Sone H., Yamazaki M., Zaha H., Zeng Y., Kurokawa Y., Tin-Tin-Win-Shwe, Hirano S.
Name of Society : 6th International Symposium on Nanotechnology, Occupational and Environmental Health (NanOEH) (2013)
Name of Proceedings : -
Determination of Measurement Conditions and Development of Analytical Methods for Use in Studying Nanoparticles in Water Using Dynamic Light Scattering.

Presenter : Nakamura A., Yamamuro M., Hirano S., Tatarazako N.
Name of Society : SETAC Asia Pacific 2012 (2012)
Name of Proceedings : Abstracts, 257
Involvement of Rho-kinase in sulfide-induced apoptosis in Jurkat cells.

Presenter : Kanno S., Hirano S., Sagi M., Chiba S., Takeshita H., Iwata T., Chiba K., Mukai T.
Name of Society : The International Association of Forensic Toxicologists (TIAFT) 2012 (2012)
Name of Proceedings : Abstracts
Cellular accumulation and behavior of silver and induction of metallothionein in human bronchial epithelial cells following exposure to silver nitrate

Presenter : Miyayama T. , Arai Y., Hirano S.
Name of Society : 51st annual meeting and ToxExpo: Society of Toxicology 2012 (2012)
Name of Proceedings : Abstracts, 2484
Hippocampus-dependent spatial learning deficit in mice following sub-chronic exposure to nanoparticle-rich diesel exhaust

Presenter : Tin-Tin-Win-Shwe, Fujitani Y., Hirano S., Fujimaki H.
Name of Society : Eurotox2011 PARIS (2011)
Name of Proceedings : Program of Eurotox2011 PARIS, 124
Distribution and biliary excretion of arsenic in rats orally administered with dipheneylarsinic acid

Presenter : Kobayashi Y., Yamashiro A, Hirano S.
Name of Society : Metallomics 2011 3rd International Symposium on Metallomics (2011)
Name of Proceedings : Poster Session of Metallomics 2011 3rd International Symposium on Metallomics
Distribution and excretion of arsenicals following a single oral administration of organic arsenic compounds in rats.

Presenter : Kobayashi Y., Mizumura A., Yamashiro A, Hirano S.
Name of Society : 4th International IUPAC Symposium for Trace Elements in Food (2011)
Name of Proceedings : Abstracts of 4th International IUPAC Symposium for Trace Elements in Food, 69
Uptake and effects of carbon nanotubes in bronchial epithelial cells

Presenter : Hirano S., Furuyama A., Fujitani Y.
Name of Society : 12th Int.Congr.Toxicol. (2010)
Name of Proceedings : Program, 79
Exposure of mammalian cells to carbon nanotubes. How do the cells react to the fiber in vitro?

Presenter : Hirano S., Furuyama A., Fujitani Y., Kanno S.
Name of Society : 4th Int.Conf.Environ.Eff.Nanopart.Nanomater. (2009)
Name of Proceedings : Abstracts
Analysis of neurotoxic effect of nanoparticle-rich diesel exhaust on a mouse brain

Presenter : Yamamoto S., Tin-Tin-Win-Shwe, Mitsushima D., Fujitani Y., Hirano S., Fujimaki H.
Name of Society : 13th Congr.Eur.Fed.Neurol.Soc. (2009)
Name of Proceedings : Abstracts, 325
Analysis of spatial learning performance and memory function-related gene expressions in the hippocampus of mice exposed to nanoparticle-rich diesel exhaust

Presenter : Tin-Tin-Win-Shwe, Yamamoto S., Fujitani Y., Hirano S., Fujimaki H.
Name of Society : 31st Annu.Meet.Jpn.Neurosci.Soc. (2008)
Name of Proceedings : Neurosci.Res., 61(Suppl.1):S258
Neurotoxic effect of nanoparticle-rich diesel exhaust in the mouse olfactory bulb

Presenter : Tin-Tin-Win-Shwe, Mitsushima D., Yamamoto S., Fujitani Y., Funabashi T., Hirano S., Fujimaki H.
Name of Society : 45th Congr.Eur.Soc.Toxicol. (2008)
Name of Proceedings : Toxicol.Lett., 180S(2008):S206

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Responses of pulmonary cells to carbon nanotubes

Presenter : Hirano S., Furuyama A.
Name of Society : 10th Int.Cof.Int.Mesothelioma Interest Group(MIG2010) (2010)
Name of Proceedings : Abstracts, 91
Immune Responses to Different Classes of Inhaled Particulates: Unique vs. Shared Responses and Mechanisms.

Presenter : Hirano S., Hollian, A.
Name of Society : Society of Toxicology 54th Annual Meeting and ToxExpo (2015)
Name of Proceedings : Abstract, 178
Inhalation study and Respiratory Toxicology.

Presenter : Hirano S.
Name of Society : 6th International Symposium on Nanotechnology, Occupational and Environmental Health (NanOEH) (2013)
Name of Proceedings : -
Cellular uptake of nanoparticles via macrophage receptor with collagenous structure

Presenter : Hirano S.
Name of Society : Int.Symp.Occup.Environ.Allerg.Immune Dis.2010(ISOEAID’10) (2010)
Name of Proceedings : Abstracts, 30

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HIRANO Seishiro

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