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AOKI Yasunobu
Deputy Director
Last Update:2009/09/01
Researcher Name AOKI Yasunobu
Div (Section) name/title Center for Environmental Risk Research(Center for Environmental Risk Research)/Deputy Director
Tel +81-29-850-2942
E-mail ybaoki (*add @nies.go.jp)
Research Subject Risk assessment of chemicals, Mechanism of in vivo mutagenesis by exposure of environmental chemicals and its evaluation
Researh Interests (あとから)
Degree(s) Ph.D.
Professional Qualification(s) Pharmacist, Teacher(Science, High School 1)
Academic Speciality Field Pharmacy,Biochemistry,Biology
Environmental Speciality Field hazardous chemical substance,health effect,risk assessment
Keyword(s) environmental mutagen,dioxins,transgenic aminal,zebrafish,in vivo mutagenesis,gene expression analysis,diesel exhaust,air pollutant,bioassay
Brief Description of Research (あとから)
Career 1982 March, Graduated from Univ. Tokyo, Graduate School of Pharmacuetical Sciences, Ph.D Course
1982 Dec., Reseacher, Basic Medical Science Division, National Institute for Environmental Studies (NIES)
1988 Jan., Research Associate, Univ. Maryland, Toxicology Program
1988 Apr. , Senior Reseacher, Environmental Health Science Division, NIES
1993 Apr. , Research Coordinator, NIES
1995 Feb. , Section Chief, Environmental Health Science Division, NIES
2001 Apr., Visiting Professor, Univ Chiba, Graduate School of Pharmacuetical Sciences
2001 Oct. , Section Chief, Research Center for Environmental Risk, NIES
2006 May, Director of Environment and Energy, Council of Science and Technology Policy, Cabnet Office
2009 Apr., Duputy Director, Research Center for Environmental Risk, NIES
Membership of Academic Society The pharmaceutical society of japan,The Japanese Environmental Mutagen Society (JEMS) ,The Japanese Biochemical Society (JBS),Society of Toxicology

Research Subject (View all list click here)
1115AA033 : Study on strategic approach of chemical risk management and control
1115AA082 : Mechanism and evaluation system of the developmental health effects of environmental factors
1115AP030 : Reference laboratory for ecotoxicity test, chemical database for environmental risk
1115AQ013 : Development and publication of databases of chemical information
1113CD011 : Involvement of oxidative stress in the epigenetic changes induced by environmental chemicals
1115AQ026 : Development of Bioassay method based on mode of action of chemical
1115AQ025 : Development of methodology for predicting ecotoxicity for risk assessment/management of chemicals
1115AQ019 : Fundamental research for risk assessment of chemicals
1115AQ015 : The reinforcement as the standard organization about the examination for ecological effect(Reference Laboratory)
1212MA001 : Commission on Preparing Guidelines on Health Risk Assessment Methods for Hazardous Air Pollutants
Research Result(Latest five records)
Publication
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Furuhama A., Aoki Y., Shiraishi H. (2012) Consideration of reactivity to acute fish toxicity of alpha,beta- unsaturated carbonyl ketones and aldehydes. Sar and Qsar in Environmental Research, 23 (1月2日), 169-184

Kawahara J., Tanaka S., Tanaka C., Aoki Y., Yonemoto J. (2011) Estimation of daily inhalation rate in preschool children using a tri-axial accelerometer: a pilot study. Science of the Total Environment , 409 (16), 3073-3077

Furuhama A., Hasunuma K., Aoki Y., Yoshioka Y., Shiraishi H. (2011) Application of chemical reaction mechanistic domains to an ecotoxicity QSAR model, the KAshinhou Tool for Ecotoxicity (KATE). SAR and QSAR in Environmental Research, 22 (5月6日), 505-523

Kawahara J., Tanaka S., Tanaka C., Aoki Y., Yonemoto J. (2011) Estimation of the respiratory ventilation rate of preschool children in daily life using accelerometers. J.Air Waste Manag.Assoc., 61 (1), 46-54

Furuhama A., Toida T., Nishikawa N., Aoki Y., Yoshioka Y., Shiraishi H. (2010) Development of an ecotoxicity QSAR model for the KAshinhou Tool for Ecotoxicity (KATE) system, March 2009 version. SAR QSAR Environ.Res. , 21 (5/6), 403-413
Presentation
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Furuhama A., Aoki Y., Shiraishi H. (2011) A reaction between alpha beta unsaturated carbonyl chemical substance, a water molecule, and thiol moiety in biomolecule: aiming to eco-toxicity prediction. Ninth Triennial Congress of the WORLD ASSOCIATION OF THEORETICAL AND COMPUTATIONAL CHEMISTS WATOC 2011, Abstracts of Ninth Triennial Congress of the WORLD ASSOCIATION OF THEORETICAL AND COMPUTATIONAL CHEMISTS WATOC 2011

Aoki Y. (2011) In vivo bioassays for assessing the total environmental risk. Environmental Health 2011 Oral programme, なし

Sato H., Nakajima D., Kageyama S., Sakashita Y., Yanagisawa R., Masumura K., Nohmi T., Aoki Y. (2010) In vivo mutagenicity of ambient air in the lungs of gpt delta transgenic mice;A case study in Tsukuba city,Japan. 2nd Asian Conf.Environ.Mutagens, Abstracts

Hasunuma K., Furuhama A., Aoki Y., Sugaya Y., Yoshioka Y., Shiraishi H. (2010) External validation of ecotoxicity prediction QSAR system,“KAshinhou Tool for Ecotoxicity” (KATE). 2nd Korea-Jpn.Symp.Environ.Chem./韓国環境分析学会秋季学術大会, Abstracts, 249

Sato H., Matsumoto M., Aoki Y., Itoh K., Yamamoto M. (2010) Functional prediction analysis based on global gene expression by using Nrf2 Knockout mouse liver exposed to TCDD. 12th Int.Congr.Toxicol., Toxicol.Lett., 196(Suppl.1), S208





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