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AOKI Yasunobu
Director
Last Update:2009/09/01
Researcher Name AOKI Yasunobu
Div (Section) name/title Center for Environmental Risk Research(Center for Environmental Risk Research)/Director
Tel +81-29-850-2942
E-mail ybaoki (*add @nies.go.jp)
Research Subject Risk assessment of chemicals, Mechanism of in vivo mutagenesis by exposure of environmental chemicals and its evaluation
Researh Interests (あとから)
Degree(s) Ph.D.
Professional Qualification(s) Pharmacist, Teacher(Science, High School 1)
Academic Speciality Field Pharmacy,Biochemistry,Biology
Environmental Speciality Field hazardous chemical substance,health effect,risk assessment
Keyword(s) environmental mutagen,dioxins,transgenic aminal,zebrafish,in vivo mutagenesis,gene expression analysis,diesel exhaust,air pollutant,bioassay
Brief Description of Research (あとから)
Career 1982 March, Graduated from Univ. Tokyo, Graduate School of Pharmacuetical Sciences, Ph.D Course
1982 Dec., Reseacher, Basic Medical Science Division, National Institute for Environmental Studies (NIES)
1988 Jan., Research Associate, Univ. Maryland, Toxicology Program
1988 Apr. , Senior Reseacher, Environmental Health Science Division, NIES
1993 Apr. , Research Coordinator, NIES
1995 Feb. , Section Chief, Environmental Health Science Division, NIES
2001 Apr., Visiting Professor, Univ Chiba, Graduate School of Pharmacuetical Sciences
2001 Oct. , Section Chief, Research Center for Environmental Risk, NIES
2006 May, Director of Environment and Energy, Council of Science and Technology Policy, Cabnet Office
2009 Apr., Duputy Director, Research Center for Environmental Risk, NIES
Membership of Academic Society The pharmaceutical society of japan,The Japanese Environmental Mutagen Society (JEMS) ,The Japanese Biochemical Society (JBS),Society of Toxicology

Research Subject (View all list click here)
1115AA033 : Study on strategic approach of chemical risk management and control
1115AP030 : Reference laboratory for ecotoxicity test, chemical database for environmental risk
1115AQ013 : Development and publication of databases of chemical information
1113CD011 : Involvement of oxidative stress in the epigenetic changes induced by environmental chemicals
1212BY008 : Investigation on water environment management method using biological responses
1115AQ026 : Development of Bioassay method based on mode of action of chemical
1115AQ025 : Development of methodology for predicting ecotoxicity for risk assessment/management of chemicals
1115AQ019 : Fundamental research for risk assessment of chemicals
1115AQ015 : The reinforcement as the standard organization about the examination for ecological effect(Reference Laboratory)
1212MA001 : Commission on Preparing Guidelines on Health Risk Assessment Methods for Hazardous Air Pollutants
1115AA082 : Mechanism and evaluation system of the developmental health effects of environmental factors
1212BY011 : Implementation of Initial Risk Assessment of Environmental chemicals in FY 2012
Research Result(Latest five records)
Publication
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Furuhama A., Aoki Y., Shiraishi H. (2012) Development of ecotoxicity QSAR models based on partial charge descriptors for acrylate and related compounds. SAR and QSAR in Environmental Research, 23 (7-8), 731-749

Furuhama A., Aoki Y., Shiraishi H. (2012) Consideration of reactivity to acute fish toxicity of alpha,beta- unsaturated carbonyl ketones and aldehydes. Sar and Qsar in Environmental Research, 23 (1-2), 169-184

Kawahara J., Tanaka S., Tanaka C., Aoki Y., Yonemoto J. (2011) Estimation of daily inhalation rate in preschool children using a tri-axial accelerometer: a pilot study. Science of the Total Environment , 409 (16), 3073-3077

Furuhama A., Hasunuma K., Aoki Y., Yoshioka Y., Shiraishi H. (2011) Application of chemical reaction mechanistic domains to an ecotoxicity QSAR model, the KAshinhou Tool for Ecotoxicity (KATE). SAR and QSAR in Environmental Research, 22 (5-6), 505-523

Kawahara J., Tanaka S., Tanaka C., Aoki Y., Yonemoto J. (2011) Estimation of the respiratory ventilation rate of preschool children in daily life using accelerometers. J.Air Waste Manag.Assoc., 61 (1), 46-54
Presentation
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Yagishita M., Kageyama S., Takemura T., Shiraishi F., Aoki Y., Shiraishi H., Wang Q., Ohshima S., Goto S., Nakajima D. (2012) Distribution of polycyclic aromatic sulfur heterocycles in total suspended particle and gaseous phase in Japan. International Symposium on Aerosols in East Asia and Their Impacts on Plants and Human Health, Abstracts, 144-145

Matsumoto M., Matsumoto Y., Aoki Y. (2012) Comparison of Risk Assessment Values of Hazardous Chemicals Estimated Based on Animal Inhalation Studies with the Guideline Values for Ambient Air Based on Epidemiological Studies. The 6th International Congress of Asian Society of Toxicology, The Journal of Toxicological Sciences (The 6th International Congress of Asian Society of Toxicology, Program and Abstracts), 37(Suppl. ?), S 412

Furuhama A., Aoki Y., Shiraishi H. (2012) Ecotoxicity QSARs Based on Partial Charge Descriptors. The 15th International Workshop on Quantitative Structure-Activity Relationships (QSAR2012) in Environmental and Health Sciences, Abstracts, 62

Aoki Y., Matsumoto Y., Matsumoto M. (2012) Comparative study on the utilities of animal experimental data for risk assessment of inhalation exposure of chemicals. SOT 2012 Annual Meeting, Abstract of SOT 2012 Annual Meeting, 27

Furuhama A., Aoki Y., Shiraishi H. (2011) A reaction between alpha beta unsaturated carbonyl chemical substance, a water molecule, and thiol moiety in biomolecule: aiming to eco-toxicity prediction. Ninth Triennial Congress of the WORLD ASSOCIATION OF THEORETICAL AND COMPUTATIONAL CHEMISTS WATOC 2011, Abstracts of Ninth Triennial Congress of the WORLD ASSOCIATION OF THEORETICAL AND COMPUTATIONAL CHEMISTS WATOC 2011





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