National Institute for Environmental Studies
Center for Health and Environmental Risk Research
 

HOME > About Us > Research Papers

Research Papers

2017 2016 2015

2015

Optimization of Neurosphere Assays using Human Neuronal Progenitor Cells for Developmental Neurotoxicity Testing
Zeng Y., Yang W., Zeng Q, Nansai H., Zhang Z., Sone H.
American Journal of Tissue Engineering and Stem Cell, 2(1):7-18 (2015)


The potential for chemical mixtures from the environment to enable the cancer hallmark of sustained proliferative signalling
Engstrom W., Darbre P., Eriksson S., Gulliver L., Hultman T., Karamouzis M.V., Klaunig J.E., Mehta R., Moorwood K., Sanderson T., Sone H., Vadgama P., Wagemaker G., Ward A., Singh N., Mulla F.A.L., Temaimi R.A.L., Amedei A., Colacci A.M., Vaccari M., Mondello C., Scovassi A.I., Raju J., Hamid R.A., Memeo L., Forte S., Roy R., Woodrick J., Salem H.K., Ryan E.P., Brown D.G., Bisson W.H.
Carcinogenesis, 36(1):38-60 (2015)


Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead
Goodson WH 3rd., Sone H.
Carcinogenesis, 36:254-296 (2015)


Determination of natural and synthetic glucocorticoids in effluent of sewage treatment plants using ultrahigh performance liquid chromatography-tandem mass spectrometry
Isobe T., Sato K., Kim J.-W., Tanabe S., Suzuki G., Nakayama K.
Environmental Science and Pollution Research, 22:14127-14135 (2015)


Augmenting effects of gestational arsenite exposure of C3H mice on the hepatic tumors of the F2 male offspring via the F1 male offspring
Nohara K., Okamura K., Suzuki T., Murai H., Michikawa T., Ito T., Shinjo K., Takumi S., Kondo Y., Hata K.
Journal of Applied Toxicology, 36(1):105-112 (2015)


A register-based study of the association between air pollutants and hypertensive disorders in pregnancy among the Japanese population
Michikawa T., Morokuma S., Fukushima K., Ueda K., Takeuchi A., Kato, Nitta H.
Environmental Research, 142:644-650 (2015)


Evaluation of elemental quantitative values of atmospheric aerosol samples by PIXE method
Saitoh K., Fushimi A., Fujitani Y., Tanabe K., Sato K., Takami A., Sera K.
International Journal of PIX, 25(1&2):13-22 (2015)


A sensitive, rapid, and simple DR-EcoScreen bioassay for the determination of PCDD/Fs and dioxin-like PCBs in environmental and food samples
Kojima H., Takeuchi S., Iida M., Nakayama S.F., Shiozaki T.
Environmental Science and Pollutant Research International (2015)


ヨーロッパエアロゾル会議2015参加報告
藤谷雄二
エアロゾル研究
, 30(4):290-291 (2015)


<書評>「環境汚染化学 有機汚染物質の動態から探る」
櫻井健郎
環境化学
, 25(4):215 (2015)


水銀の全球多媒体モデルの構築と海洋生物への移行予測
河合徹, 鈴木規之, 櫻井健郎
環境ホルモン学会ニュースレター
, 18(3):2 (2015)


Detection and measurement of the agonistic activities of PCBs and mono-hydroxylated PCBs to the costitutive androstane receptor using a recombinant yeast assay
Kamata R., Shiraishi F., Kageyama S., Nakajima D.
Toxicology in Vitro, 29:1859-1867 (2015)


DOHaDと環境化学物質
野原恵子
HORMONE FRONTIER IN GYNECOLOGY, 22(4):53-57 (2015)


PM2.5などの大気汚染と喘息発作
山崎新
THE LUNG, 23(4):391-395 (2015)


Interspecies quantitative structure-activity relationships (QSARs) for eco-toxicity screening of chemicals: the role of physicochemical properties
Furuhama A., Hasunuma K., Aoki Y.
SAR and QSAR in Environmental Research, 26(10):809-830 (2015)


Macrophage Receptor with Collagenous Structure (MARCO) Is Processed by either Macropinocytosis or Endocytosis-Autophagy Pathway
Hirano S., Kanno S.
Plos ONE, 10(11):e0142062-e0142062 (2015)


Toxic identification and evaluation of androgen receptor antagonistic activities in acid-treated liver extracts of high-trophic level wild animals from Japan
Misaki K., Suzuki G., Tue N.M., Takahashi S., Someya M., Takigami H., Tajima Y., Yamada T.K., Amano M., Isobe T., Tanabe S.
Environmental Science and Technology, 49:11840-11848 (2015)


Detection of glucocorticoid receptor agonists in effluents from sewage treatment plants in Japan
Suzuki G., Sato K., Isobe T., Takigami H., Brouwer A., Nakayama K.
Science of the Total Environment, 527-528:328-334 (2015)


第9回アジアエアロゾル会議参加報告
大谷吉生, 小島知子, 並木則和, 諏訪好英, 飯田健次郎, 田島奈穂子, 和田匡司, 反町篤行, 中山智喜, 藤谷雄二, 黒木智之, 宗村大樹, 濱大祐, 白鳥雄大, 鍵直樹
エアロゾル研究
, 30(3):209-217 (2015)


Repulsive apoptosis during exposure of mesencepharic neural stem cells to silver nanoparticles in a neurosphere assay in vitro
Ishido M., Shimaya E., Kurokawa Y., Hirano S.
Current Drug Discovery Technologies, 12(1):43-51 (2015)


Increasing Scientific Confidence in Adverse Outcome Pathways: Application of Tailored Bradford-Hill Considerations for Evaluating Weight of Evidence
Becker R. A., Ankley G. T., Edwards S.W., Kennedy S.W., Linkov I, Meek B., Sachana M., Segner H., Van Der Burg B., Villeneuve D.L., Watanabe H., Barton-Maclaren T.S.
Regulatory Toxicology and Pharmacology, 72:514-537 (2015)


無機ヒ素によるマウス肝がん増加に関連したエピジェネティック変化とDNA メチル化マーカーの探索
鈴木武博, 野原恵子
日本衛生学雑誌
, 70(3):181-185 (2015)


Patterns of Sensitization to Inhalant Allergens in Japanese Lower-Grade Schoolchildren and Related Factors
YAMAZAKI S., Shima M., Nakadate T., Ohara T., Omori T., Ono M., Sato T., Nitta H.
International Archives of Allergy and Immunology, 167(4):253-263 (2015)


Atmospheric Nanoparticles and their Potential Health Effects
Fujitani Y., Furuyama A., Hirano S.
PM2.5: Role of Oxidative Stress in Health Effects and Prevention Strategy, 143-158 (2015)


大気中微小粒子状物質(PM2.5)から生じる酸化ストレスと脳神経障害:第2部
Sagai M, Tin-Tin-Win-Shwe
Nihon Eiseigaku Zasshi, 70(3):220-229 (2015)


Health Effects of Silver Nanoparticles and Silver Ions
Miyayama T., Arai Y., Hirano S.
Biological Effects of Fibrous and Particulate Substances (2015)


Activation of transcription factors in a mouse lung following exposure to environmental chemicals and biological agents
Tin-Tin-Win-Shwe, Fujimaki H.
Journal of Toxicological Sciences, 40(5):559-568 (2015)


Explanation of non-additive effects in mixtures of similar mode of action chemicals
kamo M., Yokomizo H.
Toxicology, 335:20-26 (2015)


Exploring the drivers of wildlife population dynamics from insufficient data by Bayesian model averaging
Osada Y., Kuriyama T., Asada M., Yokomizo H., Miyashita T.
Population Ecology, 57:485-493 (2015)


Exploring the planetary boundary for chemical pollution
Diamond M.L., A. de Wit C., Molander S., Scheringer M., Backhaus T., Lohmann R., Arvidsson R., Bergman A., Hauschild M., Holoubek I., Persson L., Suzuki N., Vighi M., Zetzsch C.
Environment International, 78:8-15 (2015)


Solubility shift and SUMOylaltion of promyelocytic leukemia (PML) protein in response to arsenic(III) and fate of the SUMOylated PML
Hirano S., Tadano M., Kobayashi Y., Udagawa O., KATO A.
Toxicology and Applied Pharmacology, 287:191-201 (2015)


Towards modelling of the environmental fate of pharmaceuticals using the QSPR-MM scheme
Jagiello K., Mostrag-Szlichtyng A., Gajewicz A., Kawai T., Imaizumi Y., Sakurai T., Yamamoto H., Tatarazako N., Mizukawa K., Aoki Y., Suzuki N., Watanabe H., Puzyn T.
Environmental Modelling & Software, 72:147-154 (2015)


Role of Environmental Chemical Insult in Neuronal Cell Death and Cytoskeleton Damage
Aung KH., Tsukahara S., Maekawa F., Nohara K., Nakamura K., Tanoue A.
Biological and Pharmaceutical Bulletin, 38(8):1109-1112 (2015)


Nano-Sized Secondary Organic Aerosol of Diesel Engine Exhaust Origin Impairs Olfactory-Based Spatial Learning Performance in Preweaning Mice
Tin-Tin-Win-Shwe, Chaw Kyi Tha thu, Yadanar Moe, Maekawa F., Yanagisawa R., Furuyama A., Tsukahara, Fujitani Y., Hirano S.
Nanomaterials, 2015(5):1147-1162 (2015)


ストレスと食欲の制御分子と肥満
前川文彦, 矢田俊彦
分子精神医学
, 15(3):198-205 (2015)


野生動物管理における管理区域間移動の効果:行列モデルを用いた北海道エゾシカ(Cervus nippon yezoensis )保護管理計画の解析
Ijima H., Fujimaki A,, Ohta U., Yokomizo H., Yamamura K., Uno H., Matsuda H.
自然環境復元研究, 7(1):3-14 (2015)


Atmospheric concentration and carcinogenic risk of polycyclic aromatic hydrocarbons including benzo[c]fluorene, cyclopenta[c,d]pyrene, and benzo[j]fluoranthene in Japan
YAGISHITA M., kageyama S., Ohshima S., Matsumoto M., Aoki Y., Goto S., Nakajima D.
Atmospheric Environment, 115:263-268 (2015)


An integrated approach to tropical and subtropical island conservation
Yamano H., Satake K., Inoue T., Kadoya T., Hayashi S., Kinjo K., Nakajima D., Oguma H., Ishiguro S., Okagawa A., Suga S., Horie T., Nohara K., Fukayama N., Hibiki A.
Journal of Ecology and Environment, 38:271-279 (2015)


大気中微小粒子状物質(PM2.5)から生じる酸化ストレスと脳神経障害: 第1 部
Tin-Tin-Win-Shwe, Sagai M
日本衛生学雑誌, Japanese Journal of Hygiene, 70:127-133 (2015)


Early Exposure to Intermediate-Frequency Magnetic Fields Alters Brain Biomarkers without Histopathological Changes in Adult Mice
Tin-Tin-Win-Shwe, Shinn Ohtani, Akira Ushiyama, Naoki Kunugita
International Journal Of Environmental Research and Public Health, 12:4406-4421 (2015)


環境化学物質が誘導する発達神経毒性の評価法開発
前川文彦
日仏生物学会誌
, 54:16-22 (2015)


水生生物の保全に係る環境基準値の基本的な考え方と導出法:ノニルフェノールを事例として
林岳彦
水環境学会誌
, 38(5):173-177 (2015)


Interspecies quantitative structure-activity-activity relationships (QSAARs) for prediction of acute aquatic toxicity of aromatic amines and phenols
Furuhama A., Hasunuma K., Aoki Y.
SAR and QSAR in Environmental Research, 26(4):301-323 (2015)


Exposure to air pollution and meteorological factors associated with children's primary care visits at night due to asthma attack: case-crossover design for 3-year pooled patients
YAMAZAKI S., Shima M., Yoda Y., Oka K., Kurosaka F., Shimizu S., Takahashi H., Nakatani Y., Nishikawa J., Fujiwara K., Mizumori Y., Mogami A., Yamada T., Yamamoto N.
BMJ Open, 5: (2015)


東京湾北部海域において底層DOの減少が大型底生生物の生息に及ぼす影響
大畑聡, 赤羽祥明, 小宮朋之, 児玉圭太, 李政勲, 堀口敏宏
千葉県水産総合研究センター研究報告
, 9:27-34 (2015)


Assessment of radiocesium contamination in frogs 18 months after the Fukushima Daiichi nuclear disaster
Matsushima N., Ihara S., Takase M., Horiguchi T.
SCIENTIFIC REPORTS, 5(9712): (2015)


生態毒性データにおける急性慢性比(ACR)の算出・使用の前提となる仮定は実際に成り立っているのか?:回帰分析による検証
Hayashi T., Kashiwagi N.
日本リスク研究学会誌, Japanese Journal of Risk Analysis, 24(4):213-220 (2015)


4-Nitrophenol, 1-nitropyrene, and 9-nitroanthracene emissions in exhaust particles from diesel vehicles with different exhaust gas treatments
Inomata S., Fushimi A., Sato K., Fujitani Y., Yamada H.
Atmospheric Environment, 110:93-102 (2015)


糖尿病における中枢性摂食・代謝調節の破綻
前川文彦, 矢田俊彦
最新医学, 70(3月増刊号)
:517-523 (2015)


東京湾におけるアカガイ科貝類およびタイラギの稚貝の出現状況
石井光廣, 大畑聡, 児玉圭太, 堀口敏宏
東京湾の漁業と環境
, 6:13-15 (2015)


2013年夏季関東における微小粒子の広域観測 -PMFによる発生源寄与推定のアプローチ-
Saitoh K., Fushimi A., Tanabe K., Sato K., Fujitani Y., Takami A.
エアロゾル研究, Earozoru Kenkyu, 30(1):42-52 (2015)


Coarse particulate matter and emergency ambulance dispatches in Fukuoka, Japan: a time-stratified case-crossover study
Michikawa T., Ueda K., Takeuchi A., Tamura K., Kinoshita M., Ichinose T, Nitta H.
Environmental Health and Preventive Medicine, 20:130-136 (2015)


三河湾におけるアサリ浮遊幼生の鉛直分布に与える貧酸素水塊の影響
山田智, 岩田靖宏, 堀口敏宏, 鈴木輝明
水産海洋研究
, 79(1):1-11 (2015)


東日本大震災後のエコチル調査の在り方を考える シンポジウムの趣旨
新田裕史, 橋本浩一
小児保健研究
, 74(1):86-87 (2015)


Difference in the toxicity mechanism between ion and nanoparticle forms of silver in the mouse lung and in macrophages
Arai Y., Miyayama T., Hirano S.
Toxicology, 328:84-92 (2015)


環境問題の変遷と環境研究
中島大介
表面科学
, 36(2):91-93 (2015)


Efficient management for the Hokkaido population of sika deer Cervus nippon in Japan: accounting for migration and management cost
Ijima H., Fujimaki A., Ohta U., Yamamura K., Yokomizo H., Uno H., Matsuda H.
Population Ecology, 57:397-408 (2015)


PM2.5と呼吸器疾患
新田裕史, 上田佳代
Annual Review 2015 呼吸器, 80-84 (2015)


Diofenolan induces male offspring production through binding to the juvenile hormone receptor in Daphnia magna
Abe R., Toyota K, Miyakawa H, Watanabe H., Oka T, Miyagawa S, Nishide H, Uchiyama I, Tollefsen K E, Iguchi T, Tatarazako N.
Aquatic Toxicology, 159:44-51 (2015)


The role of Rho-kinases in IL-1β release through phagocytosis of fibrous particles in human monocytes.
Kanno S., Hirano S., Chiba S., Takeshita H., Nagai T., Takaeda M., Mukai T.
Archives of Toxicology, 89:73-85 (2015)


Degradation of Polyaromatic Hydrocarbons by Fungi Isolated from Soil in Japan
Mineki S., Suzuki K., Iwata K., Nakajima D., Goto S.
Polycyclic Aromatic Compounds, 35(1):120-128 (2015)


Particle deposition efficiency in air-liquid interface of a cell exposure chamber
Fujitani Y., Sugaya Y., Hashiguchi M., Furuyama A., Hirano S., Takami A.
Journal of Aerosol Science, 81:90-99 (2015)


Low-molecular-weight inhibitors of cell differentiation enable efficient growth of mouse iPS cells under feeder-free conditions
Donai K., Inagaki A., So K., Kuroda K., Sone H., Kobayashi M., Nishimori K., Fukuda T.
Cytotechnology, 67(2):191-197 (2015)

scroll
to top