Latest Update:2017/12/06 19:21:37

KOIKE Eiko

Researcher Name
KOIKE Eiko
Div (Section) name/title
Center for Health and Environmental Risk Research(Molecular Pathology Section)/Head
Research Subject
Studies on the cellular and molecular mechanisms of the effects of environmental chemicals on inflammatory disease
Degree(s)
PhD
Professional Qualification(s)
Medicine,Biology
Environmental Speciality Field
Environmental medicine,Immuno toxicology
Keyword(s)
Chemicals,Health effects,Inflammation,Allergy,Obesity,Immune cells
Membership of Academic Society
Japanese Society of Allergology,Japanese Society of Immunotoxicology,Japanese Society for Atmospheric Environment,The Japanese Society of Toxicology
Research Subject
  • Fiscal Year: 2017
    • 23817 : Research project on the scientific and social framework of risk assessment and management
    • 23824 : Research project on health impacts of chemicals on children and future generations
    • 23847 : Research program on health and environmental safety
    • 23896 : Study on the effects of exposure to flame retardants to the onset and/or progression of allergic asthma in obese subjects.
    • 23899 : The relationship between the gut microbiota and modern diseases
    • 23900 : Impact of brominated flame retardants in obesity and obesity-related metabolic disorders
    • 23902 : Study on the relationship between changes in gut microbiota induced by chemicals in house dust and the disturbance of higher-order biological function.
    • 23948 : Studies on the effects of environmental factors on the onset/progression of diseases
    • 23949 : Comprehensive and systematic study for control/eradication of allergic diseases via environmental and medical approaches
  • Fiscal Year: 2016
    • 23414 : Research program on health and environmental safety
    • 23415 : Research project on health impacts of chemicals on children and future generations
    • 23422 : Research project on the scientific and social framework of risk assessment and management
    • 23524 : The effects of environmental pollutants on the gut microbiota.
    • 23525 : Impact of brominated flame retardants in obesity and obesity-related metabolic disorders.
    • 23528 : Study on the effects of exposure to flame retardants to the onset and/or progression of allergic asthma in obese subjects.
    • 23558 : Studies on the effects of environmental factors on the onset/progression of diseases
    • 23743 : Comprehensive and systematic study for control/eradication of allergic diseases via environmental and medical approaches
    • 23745 : Study on the health impacts of environmental heat exposure and differences in the susceptibility
  • Fiscal Year: 2015
    • 23018 : Mechanism and evaluation system of the developmental health effects of environmental factors
    • 23065 : Effects of brominated flame retardants on the differentiation and activation of macrophages induced by saturated fatty acid
    • 23082 : Impact of brominated flame retardants in obesity and obesity-related metabolic disorders.
  • Fiscal Year: 2014
    • 22606 : Mechanism and evaluation system of the developmental health effects of environmental factors
    • 22685 : Effects of brominated flame retardants on the differentiation and activation of macrophages induced by saturated fatty acid
    • 22706 : Impact of brominated flame retardants in obesity and obesity-related metabolic disorders.
  • Fiscal Year: 2013
    • 22190 : Mechanism and evaluation system of the developmental health effects of environmental factors
    • 22277 : Effects of Asian dust aerosol on respiratory, reproductive, and immune systems.
    • 22278 : Studies on the mechanisms via which environmental pollutants enhance allergy, with special emphasis on the intercellular and intracellular networks
    • 22279 : Studies on the effects of environmental chemicals on nervous and immunological systems during developmental period
    • 22314 : Impact of brominated flame retardants in obesity and obesity-related metabolic disorders.
    • 22377 : Chemical exposure assessment of tsunami stricken areas using bioassay and chemical analysis--from the early phase through recovery activities
  • Fiscal Year: 2012
    • 21761 : Mechanism and evaluation system of the developmental health effects of environmental factors
    • 21805 : Studies on the mechanisms via which environmental pollutants enhance allergy, with special emphasis on the intercellular and intracellular networks
    • 21806 : Evaluation of biological effects of aerosol
    • 21807 : Effects of Asian dust aerosol on respiratory, reproductive, and immune systems.
    • 21808 : Studies on the effects of environmental chemicals on nervous and immunological systems during developmental period
    • 22012 : Chemical exposure assessment of tsunami stricken areas using bioassay and chemical analysis--from the early phase through recovery activities.
  • Fiscal Year: 2011
    • 21270 : Evaluation of biological effects of aerosol
    • 21271 : International comparison study on waste management and recycle institutions, and integrated system analysis of chemical substance management
    • 21272 : Studies on the mechanisms via which environmental pollutants enhance allergy, with special emphasis on the intercellular and intracellular networks
    • 21273 : Studies on the effects of environmental chemicals on nervous and immunological systems during developmental period
    • 21319 : Mechanism and evaluation system of the developmental health effects of environmental factors
    • 21661 : Effects of Asian dust aerosol on respiratory, reproductive, and immune systems.
    • 21708 : Chemical exposure assessment of tsunami stricken areas using bioassay and chemical analysis--from the early phase through recovery activities.
  • Fiscal Year: 2010
    • 21019 : Evaluation of biological effects of aerosol
    • 21020 : International comparison study on waste management and recycle institutions, and integrated system analysis of chemical substance management
    • 21022 : Study of the effects of environmental chemicals on immune cells
    • 21029 : Studies on the mechanisms via which environmental pollutants enhance allergy, with special emphasis on the intercellular and intracellular networks
    • 21031 : Studies on the effects of environmental chemicals on nervous and immunological systems during developmental period
  • Fiscal Year: 2009
    • 20400 : evaluation of biological aeffects of aerosol
    • 20447 : Study on lung function and cytokine production in pulmonary emphysema models of rodents and evaluation of effects of environmental pollutants
    • 20448 : Adverse impacts of environmental nanoparticles on sensitive respiratory disorders
    • 20460 : Study on the mechanisms of aggravation of allergy by dendritic cells exposed to environmental chemicals
    • 20461 : Study of the effects of environmental chemicals on immune cells
    • 20799 : International comparison study on waste management and recycle institutions, and integrated system analysis of chemical substance management
  • Fiscal Year: 2008
    • 20036 : Study of the effects of environmental chemicals on immune cells
    • 20037 : Study on the mechanisms of aggravation of allergy by dendritic cells exposed to environmental chemicals
    • 20147 : Development of evaluation system which can predict the effects of environmental chemicals on hypersensitive subjects with atopy using dendritic cells
    • 20153 : respiratory and immunological effects of <br>nanoparticles and nanomaterials
    • 20355 : Study on lung function and cytokine production in pulmonary emphysema models of rodents and evaluation of effects of environmental pollutants
  • Fiscal Year: 2007
    • 10421 : Development and evaluation of the in vivo model which elucidate the effects of environmental chemicasls on allergic disordes
    • 10667 : Evaluation of the effects of environmental chemicals on the differentiation and function of bone marrow-derived dendritic cells.
    • 10677 : Development of evaluation system which can predict the effects of environmental chemicals on hypersensitive subjects with atopy using dendritic cells
  • Fiscal Year: 2005
    • 9349 : Study on environmental behavior and health effects of airborne fine particulate matter such as PM2.5 and DEP
    • 9471 : Study on health effects, characteristics and environmental behavior of nano- particles
    • 9496 : Oxidative stress of particulate matter, and the effect on immune system.
    • 9640 : Development and evaluation of the in vivo model which elucidate the effects of environmental chemicasls on allergic disordes
  • Fiscal Year: 2004
    • 8985 : Study on environmental behavior and health effects of airborne fine particulate matter such as PM2.5 and DEP
    • 9144 : Study on the effect of particulate matter including DEP on immune system and the mechanisms.
    • 9189 : Study on health effects, characteristics and environmental behavior of nano- particles
    • 9247 : Oxidative stress of particulate matter, and the effect on immune system.
  • Fiscal Year: 2003
    • 8604 : Studies on the antigen presenting cells in airway
    • 8702 : Study on environmental behavior and health effects of airborne fine particulate matter such as PM2.5 and DEP
    • 8881 : Study on the effect of particulate matter including DEP on immune system and the mechanisms.
    • 8919 : Study on health effects, characteristics and environmental behavior of nano- particles
  • Fiscal Year: 2002
    • 8333 : Studies on the antigen presenting cells in airway
    • 8371 : Studies on the development of the methods to evaluate the health effects of particles
    • 8485 : Study on environmental behavior and health effects of airborne fine particulate matter such as PM2.5 and DEP
Research Result (Publication)
  • all
  • Original Paper
Research Result (Presentation)
  • all
  • Research Presentation
  • Research Presentation
    Effects of exposure to bisphenol A on memory function and neuroimmune biomarkers in allergic asthmatic mice
    Presenter : Tin-Tin-Win-Shwe, Yanagisawa R., Koike E., Takano H
    Name of Society : 24th Annual Meeting of the Japanese Society of Immunotoxicology (2017)
    Name of Proceedings : Abstracts, 84
  • Research Presentation
    Lactational exposure to benzo[a]pyrene (BaP) on neuroimmune biomarkers in hippocampus of an allergic asthmatic mouse model
    Presenter : Tin-Tin-Win-Shwe, Htike N.T.T., Tsukahara S., Koike E., Yanagisawa R.
    Name of Society : The 39th Annual Meeting of the Japan neuroscience Society (2016)
    Name of Proceedings : Abstract, 189
  • Presenter : Tin-Tin-Win-Shwe, Yanagisawa R., Koike E., Nitta H., Takano H.
    Name of Society : International Conference of Asian Environmental Chemistry 2014 (2014)
    Name of Proceedings : Abstract, 318
  • Research Presentation
    Impact of hexabromocyclododecane on lipid and glucose metabolism in high-fat diet-induced obese mice
    Presenter : YANAGISAWA Rie, TIN-TIN-Win-Shwe, KOIKE Eiko
    Name of Society : 49th Congress of the European Societies of Toxicology (2013)
    Name of Proceedings : Abstracts o the 49th Congress of the European Societies of Toxicology (EUROTOX), 221S:S252-S252
  • Research Presentation
    Brominated flame retardants stimulate immune response in vitro
    Presenter : Koike E., Yanagisawa R., Takano H
    Name of Society : 49th Congress of the European Societies of Toxicology (2013)
    Name of Proceedings : Toxicol. Lett. Abstracts o the 49th Congress of the European Societies of Toxicology (EUROTOX), 221S:S134-S134
  • Research Presentation
    Expression of neuroimmune biomarkers in hypothalamus of allergic mice after early phthalate exposure
    Presenter : Tin-Tin-Win-Shwe, Yanagisawa R., Koike E., Nakajima D., Takano H., Nitta H.
    Name of Society : Annual Meeding of Society of Indoor Environment Japan 2012 (2012)
    Name of Proceedings : Abstracts, 118-119
  • Research Presentation
    Effects of maternal exposure to Di-(2-ethylhexyl) phthalate during fetal and/or neonatal periods on atopic dermatitis in male offspring
    Presenter : Yanagisawa R., Takano H., Inoue Ken-ichiro, Koike E., Sadakane K., Ichinose T.
    Name of Society : Int.Symp.Occup.Environ.Allerg.Immune Dis.2010(ISOEAID’10) (2010)
    Name of Proceedings : Abstracts, 53
  • Research Presentation
    Effects of Di-isononyl phthalate on atopic dermatitis in vivo and immunological responses in vitro
    Presenter : Koike E., Yanagisawa R., Sadakane K., Inoue Ken-ichiro, Ichinose T., Takano H.
    Name of Society : Int.Symp.Occup.Environ.Allerg.Immune Dis.2010(ISOEAID’10) (2010)
    Name of Proceedings : Abstracts, 52
  • Research Presentation
    Impacts of latex nanomaterials on sensitive lung inflammation
    Presenter : Inoue Ken-ichiro, Takano H., Yanagisawa R., Koike E., Shimada A
    Name of Society : HORIBA/CDBIM Symp. -21st Century Adv.Mol.Toxicol.Environ.Chem.Pathog.Dis.- (2009)
    Name of Proceedings : Abstracts, 175
  • Research Presentation
    Effects of diesel exhaust particles on antigen-presenting cells and antigen-specific Th2 immunity in mice
    Presenter : Yanagisawa R., Inoue Ken-ichiro, Koike E., Takano H., Ichinose.T, Yoshino S, Yamaki K, Yoshikawa T
    Name of Society : 10th Int.Symp.Dendritic Cells (2008)
    Name of Proceedings : Abstracts, 142
  • Research Presentation
    Candida soluble cell wall β-D-glucan facilitates allergic lung inflammation via activation of antigen-presenting cells in mice
    Presenter : Inoue Ken-ichiro, Takano H., Koike E., Yanagisawa R., Oda T, Tamura H, Adachi Y, Ishibashi K, Ohno N
    Name of Society : 10th Int.Symp.Dendritic Cells (2008)
    Name of Proceedings : Abstracts, 144
  • Research Presentation
    Microarray analysis of murine lungs following pulmonary exposure to diesel exhaust particles
    Presenter : Yanagisawa R., Takano H., Koike E.
    Name of Society : 47th Annu.Meet.ToxExpo(Poster Session) (2008)
    Name of Proceedings : Program
  • Research Presentation
    Exposure to carbon black nanoparticles activates antigen-presenting cells in vivo and in vitro
    Presenter : Koike E., Yanagisawa R., Takano H.
    Name of Society : 47th Annu.Meet.ToxExpo(Poster Session) (2008)
    Name of Proceedings : Program
  • Research Presentation
    Phthalate esters modulate the differentiation of mouse peripheral blood mononuclear cells-derived dendritic cells
    Presenter : Ito T., Inoue Ken-ichiro, Koike E., Yanagisawa R., Nishimura N., Takano H.
    Name of Society : 45th Congr.Eur.Soc.Toxicol. (2008)
    Name of Proceedings : Toxicol.Lett., 180S:S117
  • Research Presentation
    Low dose effects of phthalates and other environmental chemicals on atopic dermatitis-like skin lesions in mice
    Presenter : Takano H., Yanagisawa R., Inoue Ken-ichiro., Koike E.
    Name of Society : 2nd Workshop Low Dose Eff.Chem.Spec.Consideration Phthalates (2007)
    Name of Proceedings : Abstracts
  • Research Presentation
    Size dependent chemical compositions of diesel exhaust particles in steady state and transient cycle
    Presenter : Fujitani Y., TANABE Kiyoshi, , Koike E.
    Name of Society : 16th Reg.Conf.Clean Air Environ.Asian Pac.Area(Poster Session) (2005)
    Name of Proceedings : Abstracts
  • Research Presentation
    Chemical characteristics and toxicity of polar organic extract of diesel exhaust particles
    Presenter : Koike E.
    Name of Society : Soc.Toxicol.44th Annu.Meet. (2005)
    Name of Proceedings : Abstracts
  • Research Presentation
    Organic extract of diesel exhaust particles stimulates expression of ia and costimulatory molecules associated with antigen presentation in rat peripheral blood monocytes but not aleveolar macrophages
    Presenter : Koike E.
    Name of Society : Soc.Toxicol.44th Annu.Meet. (2005)
    Name of Proceedings : Abstracts
  • Research Presentation
    Analysis of gene expression in rat alveolar epithelial cells in response to organic extravct of diesel exhaust particles
    Presenter : Koike E.
    Name of Society : Soc.Toxicol.43rd Annu.Meet. (2004)
    Name of Proceedings : Toxicologist, 78(1/5)(1-5):146-146
  • Research Presentation
    Basement membrane attenuates oxidative stress caused by organic extracts of diesel exhaust particles in rat lung microvessel endothelial cells
    Presenter : Hirano S., Mochitate K., Furuyama A., Koike E.
    Name of Society : 5th Pan Pac.Connect.Tissue Soc.Symp. (2003)
    Name of Proceedings : Abstracts, 82
  • Exposure of ozone to rats enhances antigen-presenting activity of cells in lung tissue
    Presenter : Koike E., Kobayashi T.
    Name of Society : 9th Int.Congr.Toxicol. (2001)
    Name of Proceedings : Toxicol., 164(1/3)
  • Expression of neuroimmune biomarkers in hypothalamus of allergic mice after early phthalate exposure
    Presenter : Tin-Tin-Win-Shwe, Yanagisawa R., Koike E., Nakajima D., Takano H., Nitta H.
    Name of Society : Annual Meeding of Society of Indoor Environment Japan 2012 (2012)
    Name of Proceedings : Abstracts, 118-119
  • Candida soluble cell wall β-D-glucan facilitates allergic lung inflammation via activation of antigen-presenting cells in mice
    Presenter : Inoue Ken-ichiro, Takano H., Koike E., Yanagisawa R., Oda T, Tamura H, Adachi Y, Ishibashi K, Ohno N
    Name of Society : 10th Int.Symp.Dendritic Cells (2008)
    Name of Proceedings : Abstracts, 144
  • Microarray analysis of murine lungs following pulmonary exposure to diesel exhaust particles
    Presenter : Yanagisawa R., Takano H., Koike E.
    Name of Society : 47th Annu.Meet.ToxExpo(Poster Session) (2008)
    Name of Proceedings : Program
  • Exposure to carbon black nanoparticles activates antigen-presenting cells in vivo and in vitro
    Presenter : Koike E., Yanagisawa R., Takano H.
    Name of Society : 47th Annu.Meet.ToxExpo(Poster Session) (2008)
    Name of Proceedings : Program
  • Low dose effects of phthalates and other environmental chemicals on atopic dermatitis-like skin lesions in mice
    Presenter : Takano H., Yanagisawa R., Inoue Ken-ichiro., Koike E.
    Name of Society : 2nd Workshop Low Dose Eff.Chem.Spec.Consideration Phthalates (2007)
    Name of Proceedings : Abstracts
  • Size dependent chemical compositions of diesel exhaust particles in steady state and transient cycle
    Presenter : Fujitani Y., TANABE Kiyoshi, , Koike E.
    Name of Society : 16th Reg.Conf.Clean Air Environ.Asian Pac.Area(Poster Session) (2005)
    Name of Proceedings : Abstracts
  • Chemical characteristics and toxicity of polar organic extract of diesel exhaust particles
    Presenter : Koike E.
    Name of Society : Soc.Toxicol.44th Annu.Meet. (2005)
    Name of Proceedings : Abstracts
  • Organic extract of diesel exhaust particles stimulates expression of ia and costimulatory molecules associated with antigen presentation in rat peripheral blood monocytes but not aleveolar macrophages
    Presenter : Koike E.
    Name of Society : Soc.Toxicol.44th Annu.Meet. (2005)
    Name of Proceedings : Abstracts
  • Analysis of gene expression in rat alveolar epithelial cells in response to organic extravct of diesel exhaust particles
    Presenter : Koike E.
    Name of Society : Soc.Toxicol.43rd Annu.Meet. (2004)
    Name of Proceedings : Toxicologist, 78(1/5)(1-5):146-146
  • Basement membrane attenuates oxidative stress caused by organic extracts of diesel exhaust particles in rat lung microvessel endothelial cells
    Presenter : Hirano S., Mochitate K., Furuyama A., Koike E.
    Name of Society : 5th Pan Pac.Connect.Tissue Soc.Symp. (2003)
    Name of Proceedings : Abstracts, 82
  • Effects of exposure to bisphenol A on memory function and neuroimmune biomarkers in allergic asthmatic mice
    Presenter : Tin-Tin-Win-Shwe, Yanagisawa R., Koike E., Takano H
    Name of Society : 24th Annual Meeting of the Japanese Society of Immunotoxicology (2017)
    Name of Proceedings : Abstracts, 84
  • Lactational exposure to benzo[a]pyrene (BaP) on neuroimmune biomarkers in hippocampus of an allergic asthmatic mouse model
    Presenter : Tin-Tin-Win-Shwe, Htike N.T.T., Tsukahara S., Koike E., Yanagisawa R.
    Name of Society : The 39th Annual Meeting of the Japan neuroscience Society (2016)
    Name of Proceedings : Abstract, 189
  • Presenter : Tin-Tin-Win-Shwe, Yanagisawa R., Koike E., Nitta H., Takano H.
    Name of Society : International Conference of Asian Environmental Chemistry 2014 (2014)
    Name of Proceedings : Abstract, 318
  • Impact of hexabromocyclododecane on lipid and glucose metabolism in high-fat diet-induced obese mice
    Presenter : YANAGISAWA Rie, TIN-TIN-Win-Shwe, KOIKE Eiko
    Name of Society : 49th Congress of the European Societies of Toxicology (2013)
    Name of Proceedings : Abstracts o the 49th Congress of the European Societies of Toxicology (EUROTOX), 221S:S252-S252
  • Brominated flame retardants stimulate immune response in vitro
    Presenter : Koike E., Yanagisawa R., Takano H
    Name of Society : 49th Congress of the European Societies of Toxicology (2013)
    Name of Proceedings : Toxicol. Lett. Abstracts o the 49th Congress of the European Societies of Toxicology (EUROTOX), 221S:S134-S134
  • Effects of maternal exposure to Di-(2-ethylhexyl) phthalate during fetal and/or neonatal periods on atopic dermatitis in male offspring
    Presenter : Yanagisawa R., Takano H., Inoue Ken-ichiro, Koike E., Sadakane K., Ichinose T.
    Name of Society : Int.Symp.Occup.Environ.Allerg.Immune Dis.2010(ISOEAID’10) (2010)
    Name of Proceedings : Abstracts, 53
  • Effects of Di-isononyl phthalate on atopic dermatitis in vivo and immunological responses in vitro
    Presenter : Koike E., Yanagisawa R., Sadakane K., Inoue Ken-ichiro, Ichinose T., Takano H.
    Name of Society : Int.Symp.Occup.Environ.Allerg.Immune Dis.2010(ISOEAID’10) (2010)
    Name of Proceedings : Abstracts, 52
  • Impacts of latex nanomaterials on sensitive lung inflammation
    Presenter : Inoue Ken-ichiro, Takano H., Yanagisawa R., Koike E., Shimada A
    Name of Society : HORIBA/CDBIM Symp. -21st Century Adv.Mol.Toxicol.Environ.Chem.Pathog.Dis.- (2009)
    Name of Proceedings : Abstracts, 175
  • Effects of diesel exhaust particles on antigen-presenting cells and antigen-specific Th2 immunity in mice
    Presenter : Yanagisawa R., Inoue Ken-ichiro, Koike E., Takano H., Ichinose.T, Yoshino S, Yamaki K, Yoshikawa T
    Name of Society : 10th Int.Symp.Dendritic Cells (2008)
    Name of Proceedings : Abstracts, 142
  • Phthalate esters modulate the differentiation of mouse peripheral blood mononuclear cells-derived dendritic cells
    Presenter : Ito T., Inoue Ken-ichiro, Koike E., Yanagisawa R., Nishimura N., Takano H.
    Name of Society : 45th Congr.Eur.Soc.Toxicol. (2008)
    Name of Proceedings : Toxicol.Lett., 180S:S117