Latest Update：2019/07/17 22:56:02

ISOBE Tomohiko

Researcher Name: ISOBE Tomohiko

Div (Section) name/title: Center for Health and Environmental Risk Research（Exposure Dynamics Research Section）／Senior Researcher

Research Subject: Biomonitoring of Anthropogenic Contaminants

Degree(s): Ph D

Professional Qualification(s): Chemistry,Biology,Anatomy

Environmental Speciality Field: Persistent Organic Pollutants (POPs),Endocrine Disrupting Chemicals,Exposure Science

Keyword(s): Bioaccumulation,Biological tissue analysis,Biomonitoring

Brief Description of Research: I've been working on environmental analytical chemistry. Especially I've developed some analytical methods for environmental contaminants and their metabolites in biological tissues. Now working on exposure reconstruction to assess the exposure route and level.

URL: http://www.nies.go.jp/researchers-e/200326.html
https://researchmap.jp/isobetomohiko/?lang=english
https://publons.com/researcher/1293705/tomohiko-isobe/

Research Subject

Fiscal Year: 2019
- 24694 : Sustainable Material Cycles Research Program
- 24696 : Research Program on Health and Environmental Safety
- 24712 : Assessment of Resource efficiency and Environmental Impact in the Cycles of Recyclable Materials and Accompanied Substances
- 24721 : Research Project on Health Impacts of Chemicals on Children and Future Generations
- 24722 : Project to Develop Integrated Approaches to Detecting and Assessment of Multiple and Unknown Chemicals, and Building Environmental Monitoring Networks
- 24755 : Japan Environment and Children's Study
- 24760 : Exposure Dynamics Research
- 24971 : Comprehensive measurement and spatial-temporal analysis of chemical substances in sea sediment core off Hyogo prefecture by non-target analysis method
Fiscal Year: 2018
- 24295 : Assessment of resource efficiency and environmental impact in the cycles of recyclable materials and accompanied substances
- 24304 : Research project on health impacts of chemicals on children and future generations
- 24305 : Project to develop integrated approaches to detecting and assessment of multiple and unknown chemicals, and building environmental monitoring networks
- 24338 : Japan Environment and Children
- 24353 : Sustainable Material Cycles Research Program
- 24355 : Research program on health and environmental safety
- 24499 : Exposure dynamics research
- 24570 : Non-target measurement and profile analysis of environmental pollutant in deep sea sediment core of the Japan Sea by GC×GC-HRTOFMS
Fiscal Year: 2017
- 23823 : Project to develop integrated approaches to detecting and assessment of multiple and unknown chemicals, and building environmental monitoring networks
- 23824 : Research project on health impacts of chemicals on children and future generations
- 23833 : Assessment of resource efficiency and environmental impact in the cycles of recyclable materials and accompanied substances
- 23844 : Sustainable Material Cycles Research Program
- 23847 : Research program on health and environmental safety
- 23859 : Japan Environment and Children
- 24028 : Estimation of exposure factors of soil, dust and personal care products for children and pregnant women
- 24147 : Exposure dynamics research
- 24150 : Non-target analysis for organohalogen compounds in deep sea sediments of the Japan Sea and development of accurate mass spectra database.
Fiscal Year: 2016
- 23402 : Sustainable Material Cycles Research Program
- 23404 : Assessment of resource efficiency and environmental impact in the cycles of recyclable materials and accompanied substances
- 23414 : Research program on health and environmental safety
- 23415 : Research project on health impacts of chemicals on children and future generations
- 23416 : Project to develop integrated approaches to detecting and assessment of multiple and unknown chemicals, and building environmental monitoring networks
- 23441 : Japan Environment and Children's Study
- 23573 : Estimation of exposure factors of soil, dust and personal care products for children and pregnant women.
- 23579 : Establishment of multidisciplinary strategy toward comprehensive understanding of developmental neurotoxicity induced by environmental chemicals in house dust
- 23612 : Exposure dynamics research
Fiscal Year: 2015
- 23029 : Japan Environment and Children’s Study
- 23116 : Establishment of multidisciplinary strategy toward comprehensive understanding of developmental neurotoxicity induced by environmental chemicals in house dust
- 23166 : Investigation of spatiotemporal variation of marine environmental contamination and health risk of organic pollutants using stranded cetacean as a biomarker.
- 23277 : Establishment of an international cooperation for promoting arsenic research
- 23280 : Japan Environment and Children's Study
- 23281 : Estimation of exposure factors of soil, dust and personal care products for children and pregnant women.
Fiscal Year: 2014
- 22871 : Investigation of spatiotemporal variation of marine environmental contamination and health risk of organic pollutants using stranded cetacean as a biomarker.
Fiscal Year: 2004
- 8970 : Research on new analytical methods and environmental fate of endocrine disrupters
Fiscal Year: 2003
- 8687 : Research on new analytical methods and environmental fate of endocrine disrupters
Fiscal Year: 2002
- 8472 : Research on new analytical methods and environmental fate of endocrine disrupters
Fiscal Year: 2001
- 8250 : Research on new analytical methods and environmental fate of endocrine disrupters

View all

Research Result (Publication)

all
Original Paper
Review
Other Publications

Original Paper
Evaluation of a data-processing method for target and non-target screening using comprehensive two-dimensional gas chromatography coupled with high-resolution time-of-flight mass spectrometry for environmental samples

Presenter : Ieda T., Hashimoto S., Isobe T., Kunisue T., Tanabe S.
Title : , Talanta, 194:461-468 (2019)
Original Paper
Dioxins levels in human blood after implementation of measures against dioxin exposure in Japan

Presenter : Muzembobasilua A., Iwai-Shimada M., Isobe T., Arisawa K., Shima M., Fukushima T., Nakayama S.F.
Title : , Environmental Health and Preventive Medicine, 24(6): (2019)
Original Paper
Intra-individual variations of organophosphate pesticide metabolite concentrations in repeatedly collected urine samples from pregnant women in Japan

Presenter : Hioki K., Ito Y., Oya N., Nakayama S.F., Isobe T., Ebara T., Shibata K., Nishikawa N., Nakai K., Kamida T., Ueyama J., Sugiura-Ogasawara M., Kamijima M.
Title : , Environmental Health and Preventive Medicine, 24(7): (2019)
Original Paper
Within-individual and interlaboratory variability analyses of urinary metabolites measurements of organophosphorus insecticides

Presenter : Ito Y., Ueyama J., Nakayama S.F., Isobe T., Oya N., Sato H., Ebara T., Yoshimasu K., Tsuno K., Tatsuta N., Nakai K., Kamijima M.
Title : , Journal of Exposure Science and Environmental Epidemiology (2019)
Original Paper
Association between blood manganese level during pregnancy and birth size: The Japan environment and children's study (JECS)

Presenter : Yamamoto M., Sakurai K., Eguchi A., Yamazaki S., Nakayama S.F., Isobe T., Takeuchi A., Sato T., Hata A., Mori C., Nitta H.
Title : , Environmental Research, 172:117-126 (2019)
Original Paper
Isoflavone Intake in Early Pregnancy and Hypospadias in the Japan Environment and Children's Study

Presenter : Michikawa T., Yamazaki S., Ono M., Kuroda T., Nakayama S.F., Suda E., Isobe T., Iwai M., Kobayashi Y., Yonemoto J., Tamura K., Kawamoto T., Nitta H.
Title : , Urology, 124:229-236 (2019)
Original Paper
Fish consumption in early pregnancy and congenital gastrointestinal tract atresia in the Japan Environment and Children’s Study

Presenter : Michikawa T., Yamazaki S., Ono M., Kuroda T., Nakayama S.F., Suda E., Isobe T., Iwai M., Kobayashi Y., Tamura K., Yonemoto J., Kawamoto T., Nitta H.
Title : , British Journal of Nutrition, 121(1):100-108 (2019)
Original Paper
Blood mercury, lead, cadmium, manganese and selenium levels in pregnant women and their determinants: the Japan Environment and Children's Study (JECS)

Presenter : Nakayama S.F., Iwai-Shimada M., Oguri T., Isobe T., Takeuchi A., Kobayashi Y., Michikawa T., Yamazaki S., Nitta H., Kawamoto T.
Title : , Journal of Exposure Science and Environmental Epidemiology (2019)
Review
Worldwide trends in tracing poly- and perfluoroalkyl substances (PFAS) in the environment

Presenter : Nakayama S.F., Yoshikane M., Onoda Y., Nishihama Y., Iwai-Shimada M., Takagi M., Kobayashi Y., Isobe T.
Title : , TrAC Trends in Analytical Chemistry (2019)
Original Paper
Occurrence of benzotriazole ultraviolet stabilizers (BUVSs) in human breast milk from three Asian countries

Presenter : Kim J.W., Chang K.H., Prudente M., Viet P.H., Takahashi S., Tanabe S., Kunisue T., Isobe T.
Title : , Science of the Total Environment, 655:1081-1088 (2019)
Original Paper
Association of blood mercury levels during pregnancy with infant birth size by blood selenium levels in the Japan Environment and Children's Study: A prospective birth cohort

Presenter : Kobayashi S., Kishi R., Saijo Y., Ito Y., Oba K., Araki A., Miyashita C., Itoh S., Minatoya M., Yamazaki K., Ait Bamai Y., Sato T., Yamazaki S., Nakayama S.F., Isobe T., Nitta H.
Title : , Environment International, 125:418-429 (2019)
Other Publications
Tackling the Complexity of the Exposome: Considerations from the Gunma University Initiative for Advanced Research (GIAR) Exposome Symposium

Presenter : Zhang P., Arora M., Chaleckis R., Isobe T., Jain M., Meister I., Melen E., Perzanowski M., Torta F., Wenk M.R., Wheelock C.E.
Title : , Metabolites, 9(6):106 (2019)
Original Paper
Concordance between genetic diversity and marine biogeography in a highly mobile marine mammal, the Rissos dolphin

Presenter : Chen I., Nishida S., Chou L.S., Tajima Y., Yang W.C., Isobe T., Yamada T.K., Hartman K., Hoelzel A.R.
Title : , Journal of Biogeography, 2018(00):1-12 (2018)
Original Paper
Questionnaire results on exposure characteristics of pregnant women participating in the Japan Environment and Children’s Study

Presenter : Iwai-Shimada M., Nakayama S.F., Isobe T., Michikawa T., Yamazaki S., Nitta H., Takeuchi A., Kobayashi Y., Tamura K., Suda E., Ono M., Yonemoto J., Kawamoto T.
Title : , Environmental Health and Preventive Medicine, 23(1):45 (2018)
Original Paper
Levels of TBT and other selected organotin compounds in duplicate diet samples

Presenter : Sousa A.C.A., Coelho S.D., Pastorinho M.R., Taborda-Barata L., Nogueira A.J.A., Isobe T., Kunisue T., Takahashi S., Tanabe S.
Title : , Science of the Total Environment, 574:19-23 (2017)
Original Paper
Genetic diversity of bottlenose dolphin (Tursiops sp.) populations in the western North Pacific and the conservation implications

Presenter : Chen I., Nishida S., Yang W.C., Isobe T., Tajima Y., Hoelzel A.R.
Title : , Marine Biology, 164(10):202-218 (2017)
Original Paper
Spatio-temporal trends of polybrominated dibenzo-p-dioxins and dibenzofurans in archived sediments from Tokyo Bay, Japan

Presenter : Goto A., Tue N.M., Someya M., Isobe T., Takahashi S., Tanabe S., Kunisue T.
Title : , Science of The Total Environment, 599-600:340-347 (2017)
Original Paper
Polybrominated diphenyl ethers (PBDEs) and their hydroxylated and methoxylated analogues in the blood of harbor, Dalls and finless porpoises from the Japanese coastal waters

Presenter : Ochiai M., Nomiyama K., Isobe T., Yamada T.K., Tajima Y., Matsuda A., Shiozaki A., Matsuishi T., Amano M., Iwata H., Tanabe S.
Title : , Marine Environmental Research, 128:124-132 (2017)
Original Paper
Cadmium intake in women from the University of Aveiro, Portugal - A duplicate diet study

Presenter : Coelho S.D., Maricoto T., Pastorinho M.R., Itai T., Isobe T., Kunisue T., Tanabe S., Sousa A.C.A., Nogueira A.J.A.
Title : , Journal of Geochemical Exploration, 183:187-190 (2017)
Other Publications
Baseline Profile of Participants in the Japan Environment and Children

Presenter : Michikawa T., Nitta H., Nakayama S., Yamazaki S., Isobe T., Tamura K., Suda E., Ono M., Yonemoto J., Iwai M., Kobayashi Y., Suzuki G., Kawamoto T.
Title : , Journal of Epidemiology (2017)
Original Paper
Occurrence of Natural Mixed Halogenated Dibenzo-p-Dioxins: Specific Distribution and Profiles in Mussels from Seto Inland Sea, Japan

Presenter : Goto A., Tue N.M., Someya M., Isobe T., Takahashi S., Tanabe S., Kunisue T.
Title : , Environmental Science and Technology, 51(20):11771-11779 (2017)
Original Paper
In utero and Lactational Exposure to Acetamiprid Induces Abnormalities in Socio-Sexual and Anxiety-Related Behaviors of Male Mice

Presenter : Sano K., Isobe T., Yang J., Tin-Tin-Win-Shwe, Yoshikane M., Nakayama S., Kawashima T., Suzuki G., Hashimoto S., Nohara K., Tohyama C., Maekawa F.
Title : , Frontiers in Neuroscience, 10(228): (2016)
Original Paper
Brominated, chlorinated and phosphate organic contaminants in house dust from Portugal

Presenter : Coelho S.D., Sousa A.C.A., Isobe T., Kim J.W., Kunisue T., Nogueira A.J.A., Tanabe S.
Title : , Science of the Total Environment, 569-570:442-449 (2016)
Original Paper
Brominated flame retardants and organochlorine compounds in duplicate diet samples from a Portuguese academic community

Presenter : Coelho S.D., Sousa A.C.A., Isobe T., Kunisue T., Nogueira A.J.A., Tanabe S.
Title : , Chemosphere, 160:89-94 (2016)
Original Paper
Lead in duplicate diet samples from an academic community

Presenter : Coelho S.D., Pastorinho M.R., Itai T., Isobe T., Kunisue T., Nogueira A.J.A., Tanabe S., Sousa A.C.A.
Title : , Science of The Total Environment, 573:603-607 (2016)
Original Paper
Detection of glucocorticoid receptor agonists in effluents from sewage treatment plants in Japan

Presenter : Suzuki G., Sato K., Isobe T., Takigami H., Brouwer A., Nakayama K.
Title : , Science of the Total Environment, 527-528:328-334 (2015)
Original Paper
Toxic identification and evaluation of androgen receptor antagonistic activities in acid-treated liver extracts of high-trophic level wild animals from Japan

Presenter : Misaki K., Suzuki G., Tue N.M., Takahashi S., Someya M., Takigami H., Tajima Y., Yamada T.K., Amano M., Isobe T., Tanabe S.
Title : , Environmental Science and Technology, 49:11840-11848 (2015)
Original Paper
Determination of natural and synthetic glucocorticoids in effluent of sewage treatment plants using ultrahigh performance liquid chromatography-tandem mass spectrometry

Presenter : Isobe T., Sato K., Kim J.-W., Tanabe S., Suzuki G., Nakayama K.
Title : , Environmental Science and Pollution Research, 22:14127-14135 (2015)
Original Paper
Uptake and biological effects of synthetic glucocorticoids in common carp (Cyprinus carpio)

Presenter : Nakayama K., Inoue Y., Ikeda N., Hashizume N., Murakami H., Ishibashi T., Ikeda H., Isobe T., Kitamura S., Suzuki G.
Title : , Marine Pollution Bulletin, 85(2):370-375 (2014)

View all

Evaluation of a data-processing method for target and non-target screening using comprehensive two-dimensional gas chromatography coupled with high-resolution time-of-flight mass spectrometry for environmental samples

Presenter : Ieda T., Hashimoto S., Isobe T., Kunisue T., Tanabe S.
Title : , Talanta, 194:461-468 (2019)
Dioxins levels in human blood after implementation of measures against dioxin exposure in Japan

Presenter : Muzembobasilua A., Iwai-Shimada M., Isobe T., Arisawa K., Shima M., Fukushima T., Nakayama S.F.
Title : , Environmental Health and Preventive Medicine, 24(6): (2019)
Intra-individual variations of organophosphate pesticide metabolite concentrations in repeatedly collected urine samples from pregnant women in Japan

Presenter : Hioki K., Ito Y., Oya N., Nakayama S.F., Isobe T., Ebara T., Shibata K., Nishikawa N., Nakai K., Kamida T., Ueyama J., Sugiura-Ogasawara M., Kamijima M.
Title : , Environmental Health and Preventive Medicine, 24(7): (2019)
Within-individual and interlaboratory variability analyses of urinary metabolites measurements of organophosphorus insecticides

Presenter : Ito Y., Ueyama J., Nakayama S.F., Isobe T., Oya N., Sato H., Ebara T., Yoshimasu K., Tsuno K., Tatsuta N., Nakai K., Kamijima M.
Title : , Journal of Exposure Science and Environmental Epidemiology (2019)
Association between blood manganese level during pregnancy and birth size: The Japan environment and children's study (JECS)

Presenter : Yamamoto M., Sakurai K., Eguchi A., Yamazaki S., Nakayama S.F., Isobe T., Takeuchi A., Sato T., Hata A., Mori C., Nitta H.
Title : , Environmental Research, 172:117-126 (2019)
Isoflavone Intake in Early Pregnancy and Hypospadias in the Japan Environment and Children's Study

Presenter : Michikawa T., Yamazaki S., Ono M., Kuroda T., Nakayama S.F., Suda E., Isobe T., Iwai M., Kobayashi Y., Yonemoto J., Tamura K., Kawamoto T., Nitta H.
Title : , Urology, 124:229-236 (2019)
Fish consumption in early pregnancy and congenital gastrointestinal tract atresia in the Japan Environment and Children’s Study

Presenter : Michikawa T., Yamazaki S., Ono M., Kuroda T., Nakayama S.F., Suda E., Isobe T., Iwai M., Kobayashi Y., Tamura K., Yonemoto J., Kawamoto T., Nitta H.
Title : , British Journal of Nutrition, 121(1):100-108 (2019)
Blood mercury, lead, cadmium, manganese and selenium levels in pregnant women and their determinants: the Japan Environment and Children's Study (JECS)

Presenter : Nakayama S.F., Iwai-Shimada M., Oguri T., Isobe T., Takeuchi A., Kobayashi Y., Michikawa T., Yamazaki S., Nitta H., Kawamoto T.
Title : , Journal of Exposure Science and Environmental Epidemiology (2019)
Occurrence of benzotriazole ultraviolet stabilizers (BUVSs) in human breast milk from three Asian countries

Presenter : Kim J.W., Chang K.H., Prudente M., Viet P.H., Takahashi S., Tanabe S., Kunisue T., Isobe T.
Title : , Science of the Total Environment, 655:1081-1088 (2019)
Association of blood mercury levels during pregnancy with infant birth size by blood selenium levels in the Japan Environment and Children's Study: A prospective birth cohort

Presenter : Kobayashi S., Kishi R., Saijo Y., Ito Y., Oba K., Araki A., Miyashita C., Itoh S., Minatoya M., Yamazaki K., Ait Bamai Y., Sato T., Yamazaki S., Nakayama S.F., Isobe T., Nitta H.
Title : , Environment International, 125:418-429 (2019)
Concordance between genetic diversity and marine biogeography in a highly mobile marine mammal, the Rissos dolphin

Presenter : Chen I., Nishida S., Chou L.S., Tajima Y., Yang W.C., Isobe T., Yamada T.K., Hartman K., Hoelzel A.R.
Title : , Journal of Biogeography, 2018(00):1-12 (2018)
Questionnaire results on exposure characteristics of pregnant women participating in the Japan Environment and Children’s Study

Presenter : Iwai-Shimada M., Nakayama S.F., Isobe T., Michikawa T., Yamazaki S., Nitta H., Takeuchi A., Kobayashi Y., Tamura K., Suda E., Ono M., Yonemoto J., Kawamoto T.
Title : , Environmental Health and Preventive Medicine, 23(1):45 (2018)
Levels of TBT and other selected organotin compounds in duplicate diet samples

Presenter : Sousa A.C.A., Coelho S.D., Pastorinho M.R., Taborda-Barata L., Nogueira A.J.A., Isobe T., Kunisue T., Takahashi S., Tanabe S.
Title : , Science of the Total Environment, 574:19-23 (2017)
Genetic diversity of bottlenose dolphin (Tursiops sp.) populations in the western North Pacific and the conservation implications

Presenter : Chen I., Nishida S., Yang W.C., Isobe T., Tajima Y., Hoelzel A.R.
Title : , Marine Biology, 164(10):202-218 (2017)
Spatio-temporal trends of polybrominated dibenzo-p-dioxins and dibenzofurans in archived sediments from Tokyo Bay, Japan

Presenter : Goto A., Tue N.M., Someya M., Isobe T., Takahashi S., Tanabe S., Kunisue T.
Title : , Science of The Total Environment, 599-600:340-347 (2017)
Polybrominated diphenyl ethers (PBDEs) and their hydroxylated and methoxylated analogues in the blood of harbor, Dalls and finless porpoises from the Japanese coastal waters

Presenter : Ochiai M., Nomiyama K., Isobe T., Yamada T.K., Tajima Y., Matsuda A., Shiozaki A., Matsuishi T., Amano M., Iwata H., Tanabe S.
Title : , Marine Environmental Research, 128:124-132 (2017)
Cadmium intake in women from the University of Aveiro, Portugal - A duplicate diet study

Presenter : Coelho S.D., Maricoto T., Pastorinho M.R., Itai T., Isobe T., Kunisue T., Tanabe S., Sousa A.C.A., Nogueira A.J.A.
Title : , Journal of Geochemical Exploration, 183:187-190 (2017)
Occurrence of Natural Mixed Halogenated Dibenzo-p-Dioxins: Specific Distribution and Profiles in Mussels from Seto Inland Sea, Japan

Presenter : Goto A., Tue N.M., Someya M., Isobe T., Takahashi S., Tanabe S., Kunisue T.
Title : , Environmental Science and Technology, 51(20):11771-11779 (2017)
In utero and Lactational Exposure to Acetamiprid Induces Abnormalities in Socio-Sexual and Anxiety-Related Behaviors of Male Mice

Presenter : Sano K., Isobe T., Yang J., Tin-Tin-Win-Shwe, Yoshikane M., Nakayama S., Kawashima T., Suzuki G., Hashimoto S., Nohara K., Tohyama C., Maekawa F.
Title : , Frontiers in Neuroscience, 10(228): (2016)
Brominated, chlorinated and phosphate organic contaminants in house dust from Portugal

Presenter : Coelho S.D., Sousa A.C.A., Isobe T., Kim J.W., Kunisue T., Nogueira A.J.A., Tanabe S.
Title : , Science of the Total Environment, 569-570:442-449 (2016)
Brominated flame retardants and organochlorine compounds in duplicate diet samples from a Portuguese academic community

Presenter : Coelho S.D., Sousa A.C.A., Isobe T., Kunisue T., Nogueira A.J.A., Tanabe S.
Title : , Chemosphere, 160:89-94 (2016)
Lead in duplicate diet samples from an academic community

Presenter : Coelho S.D., Pastorinho M.R., Itai T., Isobe T., Kunisue T., Nogueira A.J.A., Tanabe S., Sousa A.C.A.
Title : , Science of The Total Environment, 573:603-607 (2016)
Detection of glucocorticoid receptor agonists in effluents from sewage treatment plants in Japan

Presenter : Suzuki G., Sato K., Isobe T., Takigami H., Brouwer A., Nakayama K.
Title : , Science of the Total Environment, 527-528:328-334 (2015)
Toxic identification and evaluation of androgen receptor antagonistic activities in acid-treated liver extracts of high-trophic level wild animals from Japan

Presenter : Misaki K., Suzuki G., Tue N.M., Takahashi S., Someya M., Takigami H., Tajima Y., Yamada T.K., Amano M., Isobe T., Tanabe S.
Title : , Environmental Science and Technology, 49:11840-11848 (2015)
Determination of natural and synthetic glucocorticoids in effluent of sewage treatment plants using ultrahigh performance liquid chromatography-tandem mass spectrometry

Presenter : Isobe T., Sato K., Kim J.-W., Tanabe S., Suzuki G., Nakayama K.
Title : , Environmental Science and Pollution Research, 22:14127-14135 (2015)
Uptake and biological effects of synthetic glucocorticoids in common carp (Cyprinus carpio)

Presenter : Nakayama K., Inoue Y., Ikeda N., Hashizume N., Murakami H., Ishibashi T., Ikeda H., Isobe T., Kitamura S., Suzuki G.
Title : , Marine Pollution Bulletin, 85(2):370-375 (2014)

View all

Worldwide trends in tracing poly- and perfluoroalkyl substances (PFAS) in the environment

Presenter : Nakayama S.F., Yoshikane M., Onoda Y., Nishihama Y., Iwai-Shimada M., Takagi M., Kobayashi Y., Isobe T.
Title : , TrAC Trends in Analytical Chemistry (2019)

View all

Baseline Profile of Participants in the Japan Environment and Children

Presenter : Michikawa T., Nitta H., Nakayama S., Yamazaki S., Isobe T., Tamura K., Suda E., Ono M., Yonemoto J., Iwai M., Kobayashi Y., Suzuki G., Kawamoto T.
Title : , Journal of Epidemiology (2017)
Tackling the Complexity of the Exposome: Considerations from the Gunma University Initiative for Advanced Research (GIAR) Exposome Symposium

Presenter : Zhang P., Arora M., Chaleckis R., Isobe T., Jain M., Meister I., Melen E., Perzanowski M., Torta F., Wenk M.R., Wheelock C.E.
Title : , Metabolites, 9(6):106 (2019)

View all

Research Result (Presentation)

all
Research Presentation
Research Lecture

Research Presentation
Lessons from legacy approach of biological passive sampling - POP chemicals in mussels from asian coastal waters -

Presenter : Isobe T., Tanabe S., Kunisue T.
Name of Society : Society of Environmental Toxicology and Chemistry Asia-Pacific 2018 Conference (2018)
Name of Proceedings : Abstracts, 58-59
Research Presentation
Chemtheatre: opendata platform for environmental monitoring of pops and other contaminants

Presenter : Isobe T., Nakayama K., Uno S., Handoh I.C., Ohno N., Kunisue T.
Name of Society : Society of Environmental Toxicology and Chemistry Asia-Pacific 2018 Conference (2018)
Name of Proceedings : Abstracts, 82
Research Presentation
Disaster Response Research Development in Japan

Presenter : Nakayama SF., Takagi M., Nakajima D., Isobe T., Iwai-Shimada M., Kobayashi Y.
Name of Society : ISES-ISEE 2018 Joint Annual Meeting (2018)
Name of Proceedings : Abstracts, 655
Research Presentation
Daily Intakes of Phthalates among Japanese Children

Presenter : Takagi M., Isobe T., Iwai-Shimada M., Nakayama SF.
Name of Society : ISES-ISEE 2018 Joint Annual Meeting (2018)
Name of Proceedings : Abstracts, 1539
Research Lecture
How to Work Exposure Assessment-Large Scale Birth Cohort and Exposomics-

Presenter : Isobe T., Iwai M., Nakayama S.F.
Name of Society : The International Conference on Occupational and Environmental Diseases: ICOED (2018)
Name of Proceedings : -
Research Lecture
Japan Environment and Children’s Study (JECS) : Current Status (2018)

Presenter : Isobe T., Iwai M., Nakayama S.F., Mezawa H., Terashima K.
Name of Society : International Childhood Cancer Cohort Consortium (I4C) Childhood Leukemia International Consortium (CLIC) Joint Activities and Annual Meeting 2018 (2018)
Name of Proceedings : -
Research Presentation
Japan Environment and Children’s Study (JECS): Baseline characteristics of mothers, fathers, and their children

Presenter : Michikawa T., Nitta H., Nakayama S., Yamazaki S., Isobe T., Tamura K., Suda E., Ono M., Yonemoto J., Iwai M., Kobayashi Y., Suzuki G., Kawamoto T.
Name of Society : The 21st international Epidemiological Association, World Congress of Epidemiology (2017)
Name of Proceedings : Abstracts, 116
Research Presentation
Temporal trends of brominated flame retardants and organochlorines in melon-headed whales stranded along the Japanese coastal waters: utilization of samples and data stored in es-BANK and ChemTHEATRE

Presenter : Kunisue T., Egashira K., Isobe T., Nakayama K., Tajima Y., Yamada T.K., Tanabe S.
Name of Society : 37th International Symposium on Halogenated Persistent Organic Pollutants (POPs) - DIOXIN 2017 (2017)
Name of Proceedings : Abstracts
Research Presentation
Occurrence and potential sources of brominated/chlorinated dibenzo-p-dioxins in mussels from the Seto Inland Sea, Japan

Presenter : Goto A., Tue N.M., Someya M., Isobe T., Takahashi S., Tanabe S., Kunisue T.
Name of Society : 37th International Symposium on Halogenated Persistent Organic Pollutants (POPs) - DIOXIN 2017 (2017)
Name of Proceedings : Abstracts
Research Presentation
Biomonitoring of dioxins and other chemicals in Japan - Summary of nation-wide survey during 2011-2016

Presenter : Isobe T., Iwai M., Shibuya H., Tsukahara S., Kasamatsu J., Arisawa K., Nakayama S.
Name of Society : 37th International Symposium on Halogenated Persistent Organic Pollutants (POPs) - DIOXIN 2017 (2017)
Name of Proceedings : Abstracts
Research Presentation
Developmental exposure to tetrabromobisphenol A (TBBPA) on late onset behavior and neurological biomarkers in adult mice

Presenter : Tin-Tin-Win-Shwe, Sano K., Isobe T., Kawashima T., Suzuki G., Hashimoto S., Nakayama S., Maekawa F.
Name of Society : The 40th Annual Meeting of the Japan Neuroscience Society (2017)
Name of Proceedings : Abstract, 218
Research Presentation
Exposome: Importance of life-course total exposure assessment and current status in a large-scale cohort study

Presenter : Isobe T., Nakayama S.
Name of Society : ICCA-LRI Workshop 2017:Fit-For-Purpose Exposure Assessments for Risk-Based Decision Making (2017)
Name of Proceedings : -
Research Lecture
Japan Environment and Children’s Study (JECS): Current Status (2017)

Presenter : Isobe T., Nakayama S., Mezawa H., Terashima K.
Name of Society : 2017 International Childhood Cancer Cohort Consortium Workshop (I4C) (2017)
Name of Proceedings : -
Research Presentation
Indoor dust ingestion rate for Japanese children

Presenter : Takagi M., Isobe T., Iwai M., Nakayama S.
Name of Society : International Society of Exposure Science (ISES) 27th Annual Meeting (2017)
Name of Proceedings : Abstracts, 314-315
Research Presentation
Effects of perinatal exposure to a phosphate ester flame retardant on novel object recognition ability and memory function-related gene expression in adult mice

Presenter : Tin-Tin-Win-Shwe, Sano K., Isobe T., Kawashima T., Suzuki G., Hashimoto S., Nakayama S., Maekawa F.
Name of Society : 45th Myanmar Health Research Congress (2017)
Name of Proceedings : Abstract, 120
Research Presentation
Comprehensive analysis of house dust using GC×GC-HRTOFMS and in-house software

Presenter : Ieda T., Hashimoto S., Takazawa Y., Tanabe K., Zushi Y., Shibata Y., Maekawa F., Sano K., Suzuki G., Nakayama S., Isobe T., Tin-Tin-Win-Shwe, Kawashima T.
Name of Society : DIOXIN2016 (2016)
Name of Proceedings : Abstracts
Research Presentation
Evaluation of Bioaccessibility of PCBs, PBDEs and HBCDs in Indoor Dust: The Japan Environment and Children

Presenter : Isobe T., Takagi M., Suzuki G., Ikegami A., Kayama F., Tsuji M., Senju A., Morokuma S., Sanefuji M., Oda M., Mitsubuchi H., Kato T., Nakayama S.
Name of Society : The 36th International Symposium on Halogenated Persistent Organic Pollutants (DIOXIN 2016) (2016)
Name of Proceedings : Abstracts
Research Presentation
Perinatal exposure to a phosphate ester flame retardant affects memory function and related gene expression in adult mice

Presenter : Tin-Tin-Win-Shwe, Sano K., Isobe T., Kawashima T., Suzuki G., Hashimoto S., Nakayama S., Maekawa F.
Name of Society : The 5th Annual Meeting of The Japan Society for Developmental Origins of Health and Disease (DOHaD-Japan) (2016)
Name of Proceedings : Abstract(P-07), 40
Research Presentation
Evaluation of potentially developmentally neurotoxic chemicals using behavioral testing and neuroendocrinological analysis

Presenter : Maekawa F., Sano K., Suzuki G., Nakayama S., Isobe T., Tin-Tin-Win-Shwe, Hashimoto S., Kawashima T.
Name of Society : The 93rd Annual Meeting of the Physiological Society of Japan (2016)
Name of Proceedings : Proceedings of The 93rd Annual Meeting of the Physiological Society of Japan, 66(supplement1):S73
Research Presentation
Management of the environmental monitoring data by ChemTHEATRE, a database for environmental contaminants

Presenter : Isobe T., Nakayama K., Uno S., Ohno N., Hando I., Kunisue T.
Name of Society : The 19th Annual Meeting of Japan Society Endocrine Disruptors Research (2016)
Name of Proceedings : Program and Abstracts, 88
Research Presentation
Levels of the obesogen tributyltin and other selected organotin compounds in house dust and duplicate diet samples from Portugal

Presenter : Sousa A.C.A., Isobe T., Coelho S., Pastorinho R.M., Taborda-Barata L., Nogueira A.J.A., Kunisue T., Takahashi S., Tanabe S.
Name of Society : 5th Conference on Prenatal Programming and Toxicity (pptoxV) (2016)
Name of Proceedings : Abstracts
Research Lecture
In vivo evaluation of a flame retardant having estrogenic activity using mouse model

Presenter : Sano K., Suzuki G., Htike N.T.T., Morishita M., Tin-Tin-Win-Shwe, Hashimoto S., Kawashima T., Isobe T., Nakayama S., Tsukahara S., Maekawa F.
Name of Society : Application of Recent Advances in Neuroscience to Environmental Health Research (2016)
Name of Proceedings : abstract, 1-4
Research Lecture
Japan Environment and Children’s Study (JECS): Current Status (2016)

Presenter : Isobe T., Nakayama S.
Name of Society : Ninth International Childhood Cancer Cohort Consortium Workshop (I4C) (2016)
Name of Proceedings : -
Research Presentation
Preliminary biomonitoring data from the Japan Environment and Children’s Study

Presenter : Nakayama S.F., Isobe T., Takeuchi A., Kamijima M., Nitta H., Kawamoto T.
Name of Society : ISES 2015 (2015)
Name of Proceedings : Abstracts, 189
Research Presentation
Glucocorticoid receptor (GR) agonist profiling in the effluents from sewage treatment plants in Japan

Presenter : Suzuki G., Sato K., Isobe T., Brouwer A., Nakayama K.
Name of Society : SETAC North America 35th Annual Meeting (2014)
Name of Proceedings : Abstracts, 261
Research Presentation
Risk evaluation of glucocorticoids discharged from sewage treatment plants in Japan: Effects on the response to bacterial infection in fish

Presenter : Nakayama K., Sato K., Ikeda H., Imajuku D., Kitamura S., Isobe T., Suzuki G.
Name of Society : SETAC North America 35th Annual Meeting (2014)
Name of Proceedings : Abstarcts of SETAC North America 35th Annual Meeting, 284-285
Research Presentation
Exposomics: A key approach for next generation children’s environmental health studies

Presenter : Nakayama S.F., Isobe T., Suzuki Y., Takagi M.
Name of Society : SETAC North America 35th Annual Meeting (2014)
Name of Proceedings : -
Research Presentation
Spatial distribution, partitioning, and time trends of perfluorooctane sulfonate(PFOS) and perfluorooctanoate(PFOA) in Tokyo Bay, Japan, 2004-2006

Presenter : Sakurai T., Serizawa S., Isobe T., Kobayashi J., Kodama K., Kume G., Lee J-H., Maki H., Imaizumi Y., Suzuki N., Horiguchi T., Morita M., Shiraishi H.
Name of Society : SETAC North Am.31st Annu.Meet. (2010)
Name of Proceedings : Abstracts, 128
Research Presentation
Evaluation estrogenic activity of river water discharged into Tokyo Bay using yeast two-hybrid assays incorporating human ERα or medaka ERα and using enzyme immunoassay

Presenter : Shiraishi F., Isobe T., Kim D.M., Nishikawa T., Maruo N.(*1), Furuta Y.(*1), Shiraishi H., Morita M.
Name of Society : China-Jpn.Jt.Symp.Environ.Chem.2004 (2004)
Name of Proceedings : Proceedings

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Lessons from legacy approach of biological passive sampling - POP chemicals in mussels from asian coastal waters -

Presenter : Isobe T., Tanabe S., Kunisue T.
Name of Society : Society of Environmental Toxicology and Chemistry Asia-Pacific 2018 Conference (2018)
Name of Proceedings : Abstracts, 58-59
Disaster Response Research Development in Japan

Presenter : Nakayama SF., Takagi M., Nakajima D., Isobe T., Iwai-Shimada M., Kobayashi Y.
Name of Society : ISES-ISEE 2018 Joint Annual Meeting (2018)
Name of Proceedings : Abstracts, 655
Biomonitoring of dioxins and other chemicals in Japan - Summary of nation-wide survey during 2011-2016

Presenter : Isobe T., Iwai M., Shibuya H., Tsukahara S., Kasamatsu J., Arisawa K., Nakayama S.
Name of Society : 37th International Symposium on Halogenated Persistent Organic Pollutants (POPs) - DIOXIN 2017 (2017)
Name of Proceedings : Abstracts
Exposome: Importance of life-course total exposure assessment and current status in a large-scale cohort study

Presenter : Isobe T., Nakayama S.
Name of Society : ICCA-LRI Workshop 2017:Fit-For-Purpose Exposure Assessments for Risk-Based Decision Making (2017)
Name of Proceedings : -
Evaluation of potentially developmentally neurotoxic chemicals using behavioral testing and neuroendocrinological analysis

Presenter : Maekawa F., Sano K., Suzuki G., Nakayama S., Isobe T., Tin-Tin-Win-Shwe, Hashimoto S., Kawashima T.
Name of Society : The 93rd Annual Meeting of the Physiological Society of Japan (2016)
Name of Proceedings : Proceedings of The 93rd Annual Meeting of the Physiological Society of Japan, 66(supplement1):S73
Preliminary biomonitoring data from the Japan Environment and Children’s Study

Presenter : Nakayama S.F., Isobe T., Takeuchi A., Kamijima M., Nitta H., Kawamoto T.
Name of Society : ISES 2015 (2015)
Name of Proceedings : Abstracts, 189
Spatial distribution, partitioning, and time trends of perfluorooctane sulfonate(PFOS) and perfluorooctanoate(PFOA) in Tokyo Bay, Japan, 2004-2006

Presenter : Sakurai T., Serizawa S., Isobe T., Kobayashi J., Kodama K., Kume G., Lee J-H., Maki H., Imaizumi Y., Suzuki N., Horiguchi T., Morita M., Shiraishi H.
Name of Society : SETAC North Am.31st Annu.Meet. (2010)
Name of Proceedings : Abstracts, 128
Evaluation estrogenic activity of river water discharged into Tokyo Bay using yeast two-hybrid assays incorporating human ERα or medaka ERα and using enzyme immunoassay

Presenter : Shiraishi F., Isobe T., Kim D.M., Nishikawa T., Maruo N.(*1), Furuta Y.(*1), Shiraishi H., Morita M.
Name of Society : China-Jpn.Jt.Symp.Environ.Chem.2004 (2004)
Name of Proceedings : Proceedings
Chemtheatre: opendata platform for environmental monitoring of pops and other contaminants

Presenter : Isobe T., Nakayama K., Uno S., Handoh I.C., Ohno N., Kunisue T.
Name of Society : Society of Environmental Toxicology and Chemistry Asia-Pacific 2018 Conference (2018)
Name of Proceedings : Abstracts, 82
Daily Intakes of Phthalates among Japanese Children

Presenter : Takagi M., Isobe T., Iwai-Shimada M., Nakayama SF.
Name of Society : ISES-ISEE 2018 Joint Annual Meeting (2018)
Name of Proceedings : Abstracts, 1539
Japan Environment and Children’s Study (JECS): Baseline characteristics of mothers, fathers, and their children

Presenter : Michikawa T., Nitta H., Nakayama S., Yamazaki S., Isobe T., Tamura K., Suda E., Ono M., Yonemoto J., Iwai M., Kobayashi Y., Suzuki G., Kawamoto T.
Name of Society : The 21st international Epidemiological Association, World Congress of Epidemiology (2017)
Name of Proceedings : Abstracts, 116
Temporal trends of brominated flame retardants and organochlorines in melon-headed whales stranded along the Japanese coastal waters: utilization of samples and data stored in es-BANK and ChemTHEATRE

Presenter : Kunisue T., Egashira K., Isobe T., Nakayama K., Tajima Y., Yamada T.K., Tanabe S.
Name of Society : 37th International Symposium on Halogenated Persistent Organic Pollutants (POPs) - DIOXIN 2017 (2017)
Name of Proceedings : Abstracts
Occurrence and potential sources of brominated/chlorinated dibenzo-p-dioxins in mussels from the Seto Inland Sea, Japan

Presenter : Goto A., Tue N.M., Someya M., Isobe T., Takahashi S., Tanabe S., Kunisue T.
Name of Society : 37th International Symposium on Halogenated Persistent Organic Pollutants (POPs) - DIOXIN 2017 (2017)
Name of Proceedings : Abstracts
Developmental exposure to tetrabromobisphenol A (TBBPA) on late onset behavior and neurological biomarkers in adult mice

Presenter : Tin-Tin-Win-Shwe, Sano K., Isobe T., Kawashima T., Suzuki G., Hashimoto S., Nakayama S., Maekawa F.
Name of Society : The 40th Annual Meeting of the Japan Neuroscience Society (2017)
Name of Proceedings : Abstract, 218
Indoor dust ingestion rate for Japanese children

Presenter : Takagi M., Isobe T., Iwai M., Nakayama S.
Name of Society : International Society of Exposure Science (ISES) 27th Annual Meeting (2017)
Name of Proceedings : Abstracts, 314-315
Effects of perinatal exposure to a phosphate ester flame retardant on novel object recognition ability and memory function-related gene expression in adult mice

Presenter : Tin-Tin-Win-Shwe, Sano K., Isobe T., Kawashima T., Suzuki G., Hashimoto S., Nakayama S., Maekawa F.
Name of Society : 45th Myanmar Health Research Congress (2017)
Name of Proceedings : Abstract, 120
Comprehensive analysis of house dust using GC×GC-HRTOFMS and in-house software

Presenter : Ieda T., Hashimoto S., Takazawa Y., Tanabe K., Zushi Y., Shibata Y., Maekawa F., Sano K., Suzuki G., Nakayama S., Isobe T., Tin-Tin-Win-Shwe, Kawashima T.
Name of Society : DIOXIN2016 (2016)
Name of Proceedings : Abstracts
Evaluation of Bioaccessibility of PCBs, PBDEs and HBCDs in Indoor Dust: The Japan Environment and Children

Presenter : Isobe T., Takagi M., Suzuki G., Ikegami A., Kayama F., Tsuji M., Senju A., Morokuma S., Sanefuji M., Oda M., Mitsubuchi H., Kato T., Nakayama S.
Name of Society : The 36th International Symposium on Halogenated Persistent Organic Pollutants (DIOXIN 2016) (2016)
Name of Proceedings : Abstracts
Perinatal exposure to a phosphate ester flame retardant affects memory function and related gene expression in adult mice

Presenter : Tin-Tin-Win-Shwe, Sano K., Isobe T., Kawashima T., Suzuki G., Hashimoto S., Nakayama S., Maekawa F.
Name of Society : The 5th Annual Meeting of The Japan Society for Developmental Origins of Health and Disease (DOHaD-Japan) (2016)
Name of Proceedings : Abstract(P-07), 40
Management of the environmental monitoring data by ChemTHEATRE, a database for environmental contaminants

Presenter : Isobe T., Nakayama K., Uno S., Ohno N., Hando I., Kunisue T.
Name of Society : The 19th Annual Meeting of Japan Society Endocrine Disruptors Research (2016)
Name of Proceedings : Program and Abstracts, 88
Levels of the obesogen tributyltin and other selected organotin compounds in house dust and duplicate diet samples from Portugal

Presenter : Sousa A.C.A., Isobe T., Coelho S., Pastorinho R.M., Taborda-Barata L., Nogueira A.J.A., Kunisue T., Takahashi S., Tanabe S.
Name of Society : 5th Conference on Prenatal Programming and Toxicity (pptoxV) (2016)
Name of Proceedings : Abstracts
Glucocorticoid receptor (GR) agonist profiling in the effluents from sewage treatment plants in Japan

Presenter : Suzuki G., Sato K., Isobe T., Brouwer A., Nakayama K.
Name of Society : SETAC North America 35th Annual Meeting (2014)
Name of Proceedings : Abstracts, 261
Risk evaluation of glucocorticoids discharged from sewage treatment plants in Japan: Effects on the response to bacterial infection in fish

Presenter : Nakayama K., Sato K., Ikeda H., Imajuku D., Kitamura S., Isobe T., Suzuki G.
Name of Society : SETAC North America 35th Annual Meeting (2014)
Name of Proceedings : Abstarcts of SETAC North America 35th Annual Meeting, 284-285
Exposomics: A key approach for next generation children’s environmental health studies

Presenter : Nakayama S.F., Isobe T., Suzuki Y., Takagi M.
Name of Society : SETAC North America 35th Annual Meeting (2014)
Name of Proceedings : -

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How to Work Exposure Assessment-Large Scale Birth Cohort and Exposomics-

Presenter : Isobe T., Iwai M., Nakayama S.F.
Name of Society : The International Conference on Occupational and Environmental Diseases: ICOED (2018)
Name of Proceedings : -
Japan Environment and Children’s Study (JECS): Current Status (2017)

Presenter : Isobe T., Nakayama S., Mezawa H., Terashima K.
Name of Society : 2017 International Childhood Cancer Cohort Consortium Workshop (I4C) (2017)
Name of Proceedings : -
Japan Environment and Children’s Study (JECS): Current Status (2016)

Presenter : Isobe T., Nakayama S.
Name of Society : Ninth International Childhood Cancer Cohort Consortium Workshop (I4C) (2016)
Name of Proceedings : -
Japan Environment and Children’s Study (JECS) : Current Status (2018)

Presenter : Isobe T., Iwai M., Nakayama S.F., Mezawa H., Terashima K.
Name of Society : International Childhood Cancer Cohort Consortium (I4C) Childhood Leukemia International Consortium (CLIC) Joint Activities and Annual Meeting 2018 (2018)
Name of Proceedings : -
In vivo evaluation of a flame retardant having estrogenic activity using mouse model

Presenter : Sano K., Suzuki G., Htike N.T.T., Morishita M., Tin-Tin-Win-Shwe, Hashimoto S., Kawashima T., Isobe T., Nakayama S., Tsukahara S., Maekawa F.
Name of Society : Application of Recent Advances in Neuroscience to Environmental Health Research (2016)
Name of Proceedings : abstract, 1-4

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ISOBE Tomohiko

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