Latest Update:2017/10/05 16:16:27

ISOBE Tomohiko

Researcher Name
ISOBE Tomohiko
Div (Section) name/title
Center for Health and Environmental Risk Research(Exposure Dynamics Research Section)/Senior Researcher
Research Subject
Analysis of Anthropogenic Chemicals in Biological Samples for Exposure Assessment
Degree(s)
Ph D
Professional Qualification(s)
Chemistry,Biology,Anatomy
Environmental Speciality Field
Persistent Organic Pollutants (POPs),Endocrine Disrupting Chemicals
Brief Description of Research
I've been working on environmental analytical chemistry. Especially I'm interested in developing the analytical methods for environmental contaminants and their metabolites in biological tissues. And assessing the human exposure and route of contaminants.
Research Subject
  • Fiscal Year: 2017
    • 23823 : Project to develop integrated approaches to detecting and assessment of multiple and unknown chemicals, and building environmental monitoring networks
    • 23824 : Research project on health impacts of chemicals on children and future generations
    • 23833 : Assessment of resource efficiency and environmental impact in the cycles of recyclable materials and accompanied substances
    • 23844 : Sustainable Material Cycles Research Program
    • 23847 : Research program on health and environmental safety
    • 23859 : Japan Environment and Children
    • 24028 : Estimation of exposure factors of soil, dust and personal care products for children and pregnant women
    • 24147 : Exposure dynamics research
    • 24150 : Non-target analysis for organohalogen compounds in deep sea sediments of the Japan Sea and development of accurate mass spectra database.
  • Fiscal Year: 2016
    • 23402 : Sustainable Material Cycles Research Program
    • 23404 : Assessment of resource efficiency and environmental impact in the cycles of recyclable materials and accompanied substances
    • 23414 : Research program on health and environmental safety
    • 23415 : Research project on health impacts of chemicals on children and future generations
    • 23416 : Project to develop integrated approaches to detecting and assessment of multiple and unknown chemicals, and building environmental monitoring networks
    • 23441 : Japan Environment and Children's Study
    • 23573 : Estimation of exposure factors of soil, dust and personal care products for children and pregnant women.
    • 23579 : Establishment of multidisciplinary strategy toward comprehensive understanding of developmental neurotoxicity induced by environmental chemicals in house dust
    • 23612 : Exposure dynamics research
  • Fiscal Year: 2015
    • 23029 : Japan Environment and Children’s Study
    • 23116 : Establishment of multidisciplinary strategy toward comprehensive understanding of developmental neurotoxicity induced by environmental chemicals in house dust
    • 23166 : Investigation of spatiotemporal variation of marine environmental contamination and health risk of organic pollutants using stranded cetacean as a biomarker.
    • 23277 : Establishment of an international cooperation for promoting arsenic research
    • 23280 : Japan Environment and Children's Study
    • 23281 : Estimation of exposure factors of soil, dust and personal care products for children and pregnant women.
  • Fiscal Year: 2014
    • 22871 : Investigation of spatiotemporal variation of marine environmental contamination and health risk of organic pollutants using stranded cetacean as a biomarker.
  • Fiscal Year: 2004
    • 8970 : Research on new analytical methods and environmental fate of endocrine disrupters
  • Fiscal Year: 2003
    • 8687 : Research on new analytical methods and environmental fate of endocrine disrupters
  • Fiscal Year: 2002
    • 8472 : Research on new analytical methods and environmental fate of endocrine disrupters
  • Fiscal Year: 2001
    • 8250 : Research on new analytical methods and environmental fate of endocrine disrupters
Research Result (Publication)
  • all
  • Original Paper
Research Result (Presentation)
  • all
  • Research Presentation
  • Research Lecture
  • Presenter : Michikawa T., Nitta H., Nakayama S., Yamazaki S., Isobe T., Tamura K., Suda E., Ono M., Yonemoto J., Iwai M., Kobayashi Y., Suzuki G., Kawamoto T.
    Name of Society : The 21st international Epidemiological Association, World Congress of Epidemiology (2017)
    Name of Proceedings : Abstracts, 116
  • Research Presentation
    Developmental exposure to tetrabromobisphenol A (TBBPA) on late onset behavior and neurological biomarkers in adult mice
    Presenter : Tin-Tin-Win-Shwe, Sano K., Isobe T., Kawashima T., Suzuki G., Hashimoto S., Nakayama S., Maekawa F.
    Name of Society : The 40th Annual Meeting of the Japan Neuroscience Society (2017)
    Name of Proceedings : Abstract, 218
  • Presenter : Isobe T., Nakayama S.
    Name of Society : ICCA-LRI Workshop 2017:Fit-For-Purpose Exposure Assessments for Risk-Based Decision Making (2017)
    Name of Proceedings : -
  • Research Presentation
    Effects of perinatal exposure to a phosphate ester flame retardant on novel object recognition ability and memory function-related gene expression in adult mice
    Presenter : Tin-Tin-Win-Shwe, Sano K., Isobe T., Kawashima T., Suzuki G., Hashimoto S., Nakayama S., Maekawa F.
    Name of Society : 45th Myanmar Health Research Congress (2017)
    Name of Proceedings : Abstract, 120
  • Research Presentation
    Comprehensive analysis of house dust using GC×GC-HRTOFMS and in-house software
    Presenter : Ieda T., Hashimoto S., Takazawa Y., Tanabe K., Zushi Y., Shibata Y., Maekawa F., Sano K., Suzuki G., Nakayama S., Isobe T., Tin-Tin-Win-Shwe, Kawashima T.
    Name of Society : DIOXIN2016 (2016)
    Name of Proceedings : Abstracts
  • Research Presentation
    Evaluation of Bioaccessibility of PCBs, PBDEs and HBCDs in Indoor Dust: The Japan Environment and Children
    Presenter : Isobe T., Takagi M., Suzuki G., Ikegami A., Kayama F., Tsuji M., Senju A., Morokuma S., Sanefuji M., Oda M., Mitsubuchi H., Kato T., Nakayama S.
    Name of Society : The 36th International Symposium on Halogenated Persistent Organic Pollutants (DIOXIN 2016) (2016)
    Name of Proceedings : Abstracts
  • Research Presentation
    Perinatal exposure to a phosphate ester flame retardant affects memory function and related gene expression in adult mice
    Presenter : Tin-Tin-Win-Shwe, Sano K., Isobe T., Kawashima T., Suzuki G., Hashimoto S., Nakayama S., Maekawa F.
    Name of Society : The 5th Annual Meeting of The Japan Society for Developmental Origins of Health and Disease (DOHaD-Japan) (2016)
    Name of Proceedings : Abstract(P-07), 40
  • Research Presentation
    Evaluation of potentially developmentally neurotoxic chemicals using behavioral testing and neuroendocrinological analysis
    Presenter : Maekawa F., Sano K., Suzuki G., Nakayama S., Isobe T., Tin-Tin-Win-Shwe, Hashimoto S., Kawashima T.
    Name of Society : The 93rd Annual Meeting of the Physiological Society of Japan (2016)
    Name of Proceedings : Proceedings of The 93rd Annual Meeting of the Physiological Society of Japan, 66(supplement1):S73
  • Research Presentation
    Management of the environmental monitoring data by ChemTHEATRE, a database for environmental contaminants
    Presenter : Isobe T., Nakayama K., Uno S., Ohno N., Hando I., Kunisue T.
    Name of Society : The 19th Annual Meeting of Japan Society Endocrine Disruptors Research (2016)
    Name of Proceedings : Program and Abstracts, 88
  • Research Presentation
    Levels of the obesogen tributyltin and other selected organotin compounds in house dust and duplicate diet samples from Portugal
    Presenter : Sousa A.C.A., Isobe T., Coelho S., Pastorinho R.M., Taborda-Barata L., Nogueira A.J.A., Kunisue T., Takahashi S., Tanabe S.
    Name of Society : 5th Conference on Prenatal Programming and Toxicity (pptoxV) (2016)
    Name of Proceedings : Abstracts
  • Research Lecture
    In vivo evaluation of a flame retardant having estrogenic activity using mouse model
    Presenter : Sano K., Suzuki G., Htike N.T.T., Morishita M., Tin-Tin-Win-Shwe, Hashimoto S., Kawashima T., Isobe T., Nakayama S., Tsukahara S., Maekawa F.
    Name of Society : Application of Recent Advances in Neuroscience to Environmental Health Research (2016)
    Name of Proceedings : abstract, 1-4
  • Research Lecture
    Japan Environment and Children’s Study (JECS): Current Status (2016)
    Presenter : Isobe T., Nakayama S.
    Name of Society : Ninth International Childhood Cancer Cohort Consortium Workshop (I4C) (2016)
    Name of Proceedings : -
  • Research Presentation
    Preliminary biomonitoring data from the Japan Environment and Children’s Study
    Presenter : Nakayama S.F., Isobe T., Takeuchi A., Kamijima M., Nitta H., Kawamoto T.
    Name of Society : ISES 2015 (2015)
    Name of Proceedings : Abstracts, 189
  • Research Presentation
    Glucocorticoid receptor (GR) agonist profiling in the effluents from sewage treatment plants in Japan
    Presenter : Suzuki G., Sato K., Isobe T., Brouwer A., Nakayama K.
    Name of Society : SETAC North America 35th Annual Meeting (2014)
    Name of Proceedings : Abstracts, 261
  • Research Presentation
    Risk evaluation of glucocorticoids discharged from sewage treatment plants in Japan: Effects on the response to bacterial infection in fish
    Presenter : Nakayama K., Sato K., Ikeda H., Imajuku D., Kitamura S., Isobe T., Suzuki G.
    Name of Society : SETAC North America 35th Annual Meeting (2014)
    Name of Proceedings : Abstarcts of SETAC North America 35th Annual Meeting, 284-285
  • Research Presentation
    Exposomics: A key approach for next generation children’s environmental health studies
    Presenter : Nakayama S.F., Isobe T., Suzuki Y., Takagi M.
    Name of Society : SETAC North America 35th Annual Meeting (2014)
    Name of Proceedings : -
  • Presenter : Sakurai T., Serizawa S., Isobe T., Kobayashi J., Kodama K., Kume G., Lee J-H., Maki H., Imaizumi Y., Suzuki N., Horiguchi T., Morita M., Shiraishi H.
    Name of Society : SETAC North Am.31st Annu.Meet. (2010)
    Name of Proceedings : Abstracts, 128
  • Research Presentation
    Evaluation estrogenic activity of river water discharged into Tokyo Bay using yeast two-hybrid assays incorporating human ERα or medaka ERα and using enzyme immunoassay
    Presenter : Shiraishi F., Isobe T., Kim D.M., Nishikawa T., Maruo N.(*1), Furuta Y.(*1), Shiraishi H., Morita M.
    Name of Society : China-Jpn.Jt.Symp.Environ.Chem.2004 (2004)
    Name of Proceedings : Proceedings
  • Japan Environment and Children’s Study (JECS): Current Status (2016)
    Presenter : Isobe T., Nakayama S.
    Name of Society : Ninth International Childhood Cancer Cohort Consortium Workshop (I4C) (2016)
    Name of Proceedings : -
  • In vivo evaluation of a flame retardant having estrogenic activity using mouse model
    Presenter : Sano K., Suzuki G., Htike N.T.T., Morishita M., Tin-Tin-Win-Shwe, Hashimoto S., Kawashima T., Isobe T., Nakayama S., Tsukahara S., Maekawa F.
    Name of Society : Application of Recent Advances in Neuroscience to Environmental Health Research (2016)
    Name of Proceedings : abstract, 1-4