Latest Update:2017/12/06 19:21:21

KOBAYASHI Yayoi

KOBAYASHI Yayoi
Researcher Name
KOBAYASHI Yayoi
Div (Section) name/title
Center for Health and Environmental Risk Research(Exposure Dynamics Research Section)/Senior Researcher
Research Subject
Elucidation of metabolic pathway of metaloid by analytical toxicology
Degree(s)
Ph.D
Professional Qualification(s)
Pharmacy,Chemistry
Environmental Speciality Field
toxicology,Environmental harmful metal
Keyword(s)
analytical toxicology,HPLC-ICP-MS analysis,LC-MS analysis,metabolism,arsenic,selenium,animal experiment
Membership of Academic Society
The pharmaceutical society of japan,Japan Society for Biomedical Research on Trace Elements,The Japanese Society of Toxicology,Japanese Arsenic Scientist
Research Subject
  • Fiscal Year: 2017
    • 23823 : Project to develop integrated approaches to detecting and assessment of multiple and unknown chemicals, and building environmental monitoring networks
    • 23824 : Research project on health impacts of chemicals on children and future generations
    • 23833 : Assessment of resource efficiency and environmental impact in the cycles of recyclable materials and accompanied substances
    • 23844 : Sustainable Material Cycles Research Program
    • 23847 : Research program on health and environmental safety
    • 23859 : Japan Environment and Children
    • 24119 : Elucidation of the metabolism and toxicity mechanism of arsenolipids by analytical chemistry techniques
    • 24120 : Cerebellar symptoms and glial cells due to organic arsenic compound : arsenic metabolism in the brain and the collapse of glutathione control (Subtheme)Elucidation of the metabolism of organic arsenicals by analytical chemistry techniques
    • 24122 : Elucidation of carcinogenic mechanisms by the organic arsenic compounds (Subtheme) Metabolism and health risk assessment of arsenic compound in food
    • 24147 : Exposure dynamics research
  • Fiscal Year: 2016
    • 23402 : Sustainable Material Cycles Research Program
    • 23404 : Assessment of resource efficiency and environmental impact in the cycles of recyclable materials and accompanied substances
    • 23414 : Research program on health and environmental safety
    • 23415 : Research project on health impacts of chemicals on children and future generations
    • 23416 : Project to develop integrated approaches to detecting and assessment of multiple and unknown chemicals, and building environmental monitoring networks
    • 23441 : Japan Environment and Children's Study
    • 23550 : Elucidation of the metabolism and toxicity mechanism of arsenolipids by analytical chemistry techniques
    • 23568 : Cerebellar symptoms and glial cells due to organic arsenic compound : arsenic metabolism in the brain and the collapse of glutathione control (Subtheme)Elucidation of the metabolism of organic arsenicals by analytical chemistry techniques
    • 23569 : Elucidation of carcinogenic mechanisms by the organic arsenic compounds (Subtheme) Metabolism and health risk assessment of arsenic compound in food
    • 23612 : Exposure dynamics research
  • Fiscal Year: 2015
    • 23017 : Development of epidemiological methods for evaluating health effects of exposure to environmental pollutants
    • 23129 : Development of analytical methods for elucidation of metabolism and toxicity of arsenolipids
    • 23192 : The role of selenium in the arsenometabolomics
    • 23277 : Establishment of an international cooperation for promoting arsenic research
    • 23286 : Analysis of the effect of inorganic arsenite on reproductive function
  • Fiscal Year: 2014
    • 22605 : Development of epidemiological methods for evaluating health effects of exposure to environmental pollutants
    • 22722 : Establishment of an international cooperation for promoting arsenic research
    • 22801 : The role of selenium in the arsenometabolomics
    • 22908 : Analysis of the effect of inorganic arsenite on reproductive function
  • Fiscal Year: 2013
    • 22189 : Development of epidemiological methods for evaluating health effects of exposure to environmental pollutants
    • 22256 : Characterization of arsenic-binding proteins and its application to toxicity evaluation.
    • 22440 : Role of intestinal microflora in absorption and excretion of arsenic compounds
    • 22442 : The role of selenium in the arsenometabolomics
    • 22475 : Exploration of molecular epidemiological indexes to health effects of environmental factors focusing on genetic and epigenetic mutation
    • 22544 : Establishment of an international cooperation for promoting arsenic research
  • Fiscal Year: 2012
    • 21760 : Development of epidemiological methods for evaluating health effects of exposure to environmental pollutants
    • 21917 : Characterization of arsenic-binding proteins and its application to toxicity evaluation.
    • 21986 : Studies of factors contributing to the regulation of epigenetics
    • 22139 : Role of intestinal microflora in absorption and excretion of arsenic compounds
    • 22140 : A study on evaluation of effects of environmental pollutants by analytical toxicology.
  • Fiscal Year: 2011
    • 21318 : Development of epidemiological methods for evaluating health effects of exposure to environmental pollutants
    • 21388 : Characterization of arsenic-binding proteins and its application to toxicity evaluation.
    • 21416 : A study on evaluation of effects of environmental pollutants by analytical toxicology.
    • 21417 : Role of intestinal microflora in absorption and excretion of arsenic compounds
    • 21480 : Studies of factors contributing to the regulation of epigenetics
  • Fiscal Year: 2010
    • 21046 : A study on analytical toxicology of metatolism of arsenic.
    • 21051 : Studies to evaluate toxicityies of environmental chemicals focusing on their epigenetic effects
    • 21053 : Studies of factors contributing to the regulation of epigenetics
    • 21161 : A study on evaluation of effects of environmental pollutants by analytical toxicology.
  • Fiscal Year: 2009
    • 20457 : A study on analytical toxicology of metatolism of arsenic.
    • 20458 : A study on metabolomics of metaloid
    • 20459 : Development of aqeuous-chromatography sysytems to reduce environmental pollutant load.
    • 20483 : Studies to evaluate toxicityies of environmental chemicals focusing on their epigenetic effects
  • Fiscal Year: 2008
    • 20109 : Redox and detoxification mecanism of arsenic.
    • 20111 : A study on metabolomics of metaloid
    • 20113 : A study on analytical toxicology of metatolism of arsenic.
    • 20139 : Studies to evaluate toxicityies of environmental chemicals focusing on their epigenetic effects
    • 20253 : Development of aqeuous-chromatography sysytems to reduce environmental pollutant load.
  • Fiscal Year: 2007
    • 10458 : A study on metabolomics of metaloid
    • 10463 : Development of aqeuous-chromatography sysytems to reduce environmental pollutant load.
    • 10739 : Studies to evaluate toxicityies of environmental chemicals focusing on their epigenetic effects
  • Fiscal Year: 2006
    • 10179 : A study on metabolomics of metaloid
    • 10184 : Development of aqeuous-chromatography sysytems to reduce environmental pollutant load.
    • 10199 : Redox and detoxication mechanism of arsenic in in vivo.
  • Fiscal Year: 2005
    • 9672 : A study on metabolomics of metaloid
    • 9678 : Development of aqeuous-chromatography sysytems to reduce environmental pollutant load.
  • Fiscal Year: 2004
    • 9224 : Proof of a novel metabolic pathway of arsenic.
Research Result (Publication)
  • all
  • Original Paper
  • Review
  • Other Publications
  • Metabolism and the paradoxical effects of arsenic: Carcinogenesis and anticancer
    Presenter : Cui X, Kobayashi Y., Akashi M, Okayasu R
    Title : , Curr.Med.Chem., 15:2293-2304 (2008)
  • Elucidation of the metabolic pathways of selenium and arsenic by analytical toxicology
    Presenter : Kobayashi Y.
    Title : , J.Health Sci., 56(2):154-160 (2010)
Research Result (Presentation)
  • all
  • Research Presentation