Publication List


英 文

2008:

Huang F, Yamaki K, Tong X, Fu L, Zhang R, Cai Y, Yanagisawa R, Inoue KI, Takano H, Yoshino S: Inhibition on the antigen-induced activation of RBL-2HS cells by sinomenine. Int Immunopharm 8: 502-503, 2008.

Yoshida S., Hiyoshi K, Ichinose T., Takano H., Oshio S., Sugawara I., Takeda K., Shibamoto T. Effect of Nanoparticles on the Male Reproductive Function of Mice. International Journal of Andrology. (2008), in press.

Ichinose T., Yoshida S., Hiyoshi K., Sadakane K.,
Takano H., Nishikawa M., Mori I., Yanagisawa R., Kawazato H., Yasuda A., Shibamoto T.
 Effects of microbial materials adhered to Asian sand dust (ASD) on Allergic Lung Inflammation. Arch. Environ. Contam. Toxicol. (2008), in press.

Ichinose T., Yoshida S., Sadakane K.,
Takano H., Yanagisawa R., Inoue K., Nishikawa M., Mori I., Yanagisawa R., Kawazato H., Yasuda A., Shibamoto T. Effects of Asian sand dust, Arizona sand dust, amorphous silica and aluminum oxide on allergic inflammation in the murine lung. Inhalation Toxicology (2008), in press.

Inoue K, Takano H, Kumagai Y. Pin1 blockade in asthma by naphthoquinone? J Allergy Clin Immunol (correspondence: in press).

2007:

Inoue K, Takano H, Ohnuki M, Yanagisawa R, Sakurai M, Shimada A, Mizushima K, Yoshikawa T. Size effects of nanomaterials on lung
inflammation and coagulatory disturbance. Int J Immunopathol Pharmacol (in press).

Saito F, Tasaka S, Inoue K, Miyamoto K, Nakano Y, Ogawa Y, Yamada W, Shiraishi Y, Hasegawa N, Fujishima S, Takano H, Ishizaka A. Role of interleukin-6 in bleomycin-induced lung inflammatory changes in mice. Am J Respir Cell Mol Biol (in press).

Feng H, Yamaki K, Takano H, Inoue K, Yanagisawa R, Yoshino S: Effect of sinomenine on collagen-induced arthritis in mice. Autoimmunity 40 (7):.532-539, 2007.

Inoue H, Shimada A, Kaewamatawong T, Morita T, Ohta Y, Inoue K, Takano H: Ultrastructural changes of the air-blood-barrier in mice after intratracheal instillation of lipopolysaccharide and ultrafine carbon black particles. Exp Toxicol Pathol (in press)

Inoue K, Takano H, Yanagisawa R, Sakurai M, Abe S, Yoshino S, Yamaki K, Yoshikawa T, Effects of nanoparticles on lung physiology in the presence or absence of antigen, Int J Immunopathol Pharmacol, (in press).

Koike E, Takano H, Inoue K, Yanagisawa R, Sakurai M, Aoyagi H, Shinohara R, Kobayashi T: Pulmonary exposure to carbon black nanoparticles increases the number of antigen-presenting cells in murine lung. Int J Immunopathol Pharmacol  (in press)

Wakahara K, Tanaka H, Takahashi G, Tamari M, Nasu R, Toyohara T, Takano H, Saito S, Inagaki N, Shimaoka K, Nagai H. Repeated instillations of Dermatophagoides farinae into the airways can induce Th2-dependent airway hyperresponsiveness, eosinophilia and remodeling in mice-Effect of intratracheal treatment of fluticasone propionate-. Eur J pharmacol (in press)

Hashimoto AH, Amanuma K, Hiyoshi K, Sugawara Y, Goto S, Yanagisawa R, Takano H, Masumura KI, Nohmi T, Aoki Y: Mutations in the lungs of gpt-delta transgenic mice following inhalation of diesel exhaust. Environ Mol Mutagen (in press).

Inoue K, Takano H, Yanagisawa R, Sakurai M, Abe S, Yoshino S, Yamaki K, Yoshikawa T. Effects of components derived from diesel exhaust particles on lung physiology related to antigen. Immunopharm Immunotoxicol (in press).

Yamaki K, Taneda S, Yanagisawa R, Inoue KI, Takano H, Yoshino S. Enhancement of allergic responses in vivo and in vitro by butylated hydroxytoluene. Toxicol Appl Pharmacol (in press)

Li L, Shoji W, Takano H, Nishimura N, Aoki Y, Takahashi R, Goto S, Kaifu T, Takai T, Obinata M. Increased susceptibility of MER5 (peroxiredoxin 」)knockout mice to LPS-induced oxidative stress. Biochem Biophys Res Commun 355(3) 715-721, 2007.

Aoki Y, Hashimoto AH, Amanuma K, Matsumoto M, Hiyoshi K, Takano H, Masumura K, Itoh K, Nohmi T, Yamamoto M. Enhanced Spontaneous and Benzo(a)pyrene-Induced Mutations in the Lung of Nrf2-Deficient gpt Delta Mice. Cancer Res 67 (12): 5643-5648, 2007.

Inoue K, Takano H, Oda T, Yanagisawa R, Tamura H, Ohno N, Adachi Y, Shimada A, Ichinose T, Yoshikawa T. Candida soluble cell wall β-glucan induces lung inflammation in mice. Int J Immunopathol Pharmacol ( in press)

Inoue K, Takano H, Yanagisawa R, Hirano S, Kobayashi T, Fujitani Y, Shimada A, Yoshikawa T. Effects of inhaled nanoparticles on acute lung injury induced by lipopolysaccharide in mice. Toxicology (in press)

Yanagisawa R, Takano H, Ichinose T, Mizushima K, Nishikawa M, Mori I, INoue K, Sadakane K, Yoshikawa T. Gene expression analysis of murine lungs following pulmonary exposure to Asian sand dust particles.  Exp Biol Med (in press)

Inoue K, Takano H, Yanagisawa R, Sakurai M, Shimada A, Morita T, Sato M, Yoshino S, Yoshikawa T.Roles of interleukin-6 in Toll-like receptor 4 and 2 expressions induced by lipopolysaccharide in the lung.  Immunophaem Immunotoxicol (in press)

Inoue K, Takano H, Ichinose T, Tomura S, Yanagisawa R, Sakurai M, Sumi D, Cho AK, Hiyoshi K, Kumagai Y. Effects of naphthoquinone on airway responsiveness in the presence or absence of antigen in mice. Arch Toxicol (in press)

Tomaru M, Takano H, Osakabe N, Yasuda A, Inoue K, Yanagisawa R, Oowatari T, Uematsu H. Dietary supplementation with cacao liquor proanthocyanidins prevents elevation of blood glucose levels in diabetic obese mice. Nutrition (in press)

Arimoto T, Takano H, Inoue K, Yanagisawa R, Yoshino, Yamaki K, Yoshikawa T.Pulmonary exposure to diesel exhaust particle components enhances circulatory chemokines during lung inflammation. Int J Immunopatol Pharmacol (in press)

2006:

Kaewamatawong T, Shimada A, Okajima M, Inoue H, Morita T, Inoue K, Takano H. Acute and Subacute Pulmonary Toxicity of Low Dose of Ultrafine Colloidal Silica Particles in Mice after Intratracheal Instillation. Toxicol Pathol 34: 2006 in press

Takano H, Yanagisawa R, Inoue K. Components of diesel exhaust particles diversely enhance a variety of respiratory diseases related to infection or allergy-Extracted organic chemicals and the residual particles after extraction differently affect respiratory diseases-. J Clin Biochem Nutr (in press) (review)

Kobayashi K, Kuroda J, Shibata N, Hasegawa T, Seko Y, Satoh M, Tohyama C, Takano H, H, IMURA N, Sakabe K, Fujishiro H, Himeno s. Induction of metallothionein by manganese is completely dependent on interleukin-6 production. J Pharmacol Exp Ther (in press)

Inoue K, Takano H, Hiyoshi K, Ichinose T, Sadakane K, Yanagisawa R, Tomura S, Kumagai Y. Naphthoquinone enhances antigen- related airway inflammation in mice. Eur Respir J (in press).

Inoue K, Takano H, Yanagisawa R, Sakurai M, Ueki N, Yoshikawa T. Effects of diesel exhaust particles oncytokine production by splenocytes stimulated with lipopolysaccharide. J Appl Toxicol (in press)

Feng H, Yamaki K, Takano H, Inoue K, Yanagisawa R, Yoshino S. Suppression of Th1 and Th2 immune responses in mice by sinomenine, an alkaloid extracted from the Chinese medicinal plant sinomenium acutum.  Planta Medica, in press (2006).

Yamaki K, Li X, Hossain Md A, Khurshid Alam AHM, Taneda S, Yanagisawa R,Takano H, Yoshino S. Differential effects of the phosphodiesterase IV inhibitor rolipram and varying types of anti-arthritic drugs on antigen-induced arthritis in mice.  Immunol. Invest., in press (2006).

Tomaru M, Takano H, Inoue K, Yanagisawa R, Osakabe N, Yasuda A, Shimada A, Kato Y, Uematsu H: Pulmonary exposure to diesel exhaust particles enhances fatty changes of the liver in obese diabetic mice, Int J Mol Med, (in press)

Yoshida S, Ono N, Tsukue N, Oshio S, Umeda T, Takano H, Takeda K: In utero exposure to diesel exhaust increased accessory reproductive gland weight and serum testosterone concentration in male mice, Environ Sci, vol. 13, 139-147, 2006

Takano H, Yanagisawa R, Inoue K, Ichinose T, Sadakane K, Yoshikawa T: Di-(2-ethylhexyl) phthalate enhances atopic dermatitis-like skin lesions in mice, Environ Health Persp, vol. 114, 1266-1269, 2006

Inoue K, Takano H, Yanagisawa R, Hirano S, Sakurai M, Shimada A, Yoshikawa T: Effects of airway exposure to nanoparticles on lung inflammation induced by bacterial endotoxin in mice, Environ Health Persp, vol. 114, 1325-1330, 2006

Inoue K, Takano H, Yanagisawa R, Sakurai M, Ueki N, Yoshikawa T. Effects of diesel exhaust on lung inflammation related to bacterial endotoxin in mice. Pharmacol Toxicol (in press)

Inoue K, Takano H, Sakurai M, Oda T, Tamura H, Yanagisawa R, Ichinose T, Shimada A, Yoshino S, Yoshikawa T: Pulmonary exposure to diesel exhaust
particles enhances coagulatory disturbance with endothelial damage and systemic inflammation Related to Lung Inflammation. Exp BiolMed (in press)

 Sadakane K, Ichinose T, Takano H, Abe M, Sera N, Yanagisawa R, Ochi H, Fujioka K, Lee KG, Shibamoto T: Murine strain differences in 8-hydroxy-deoxyguanosine formation in hepatic DNA by oxidized lard and dietary oils, Food Chem Toxicol, vol. 44, 1372-1376, 2006

Inoue K, Takano H, Yanagisawa R, Hirano S, Kobayashi T, Ichinose T, Yoshikawa T. Effects of organic chemicals derived from ambient particulate matter on lung inflammation related to lipopolysaccharide. Arch Toxicol (in press)

Inoue K, Takano H, Yanagisawa R, Sakurai M, Shimada A, Sato M, Yoshino S, Yoshikawa T: Role of interleukin-6 in fibrinolytic changes induced by lipopolysaccharide in mice, Blood Coagulation and Fibrinolysis, vol. 17, 307-309, 2006

Hashimoto AH, Amanuma K, Hiyoshi K, Takano H, Masumura KI, Nohmi T, Aoki Y: In vivo mutagenesis in the lungs of gpt-delta transgenic mice treated with 1,6-dinitropyrene, Environ Mol Mutagen, vol. 47, 277-283, 2006

Sugamata M, Ihara T, Takano H, Oshio S, Takeda K: Maternal diesel exhaust exposure damages newborn murine brains. J Health Sciences 52: 82-84, 2006.

Inoue K, Takano H, Yanagisawa R, Ichinose T, Sakurai M, Yoshikawa T: Effects of nano particles on cytokine expression in murine lung in the absence or presence of allergen, Arch Toxicol, vol. 80, 614-619, 2006

 Inoue K, Takano H, Shiga A, Fujita Y, Makino H, Yanagisawa R, Kato Y, Yoshikawa T: Effects of volatile constituents of rosemary extract on lung inflammation induced by diesel exhaust particles, Pharmacol Toxicol, vol. 99, 52-57, 2006

Arimoto T, Inoue K, Yanagisawa R, Takano H: Diesel exhaust particles synergistically enhance lung injury and oxadative stress induced by bacterial endotoxin. J Clin Biochem Nutr (review: in press)

Ichinose T, Sadakane K, Takano H, Yanagisawa R, Nishikawa M, Mori I, Kawazato H, Yasuda A, Hiyoshi K, Shibamoto T: Enhancement of mite allergen-induced eosinophil infiltration in the murine airway and  local cytokine/chemokine expression by Asian sand dust, J Toxicol Environ Health A, vol. 69, 1571-1585, 2006

Yanagisawa R, Takano H, Inoue K, Sakurai M, Ichinose T, Sadakane K, Yoshino S, Yamaki K, Yoshikawa T, Hayakawa K: Components of diesel exhaust particles differentially affect Th1/Th2 response in a murine model of allergic airway inflammation, Clin Exp Allergy, vol. 36, 386-395, 2006

Inoue K, Takano H, Shimada A, Wada E, Yanagisawa R, Sakurai M, Satoh M, Yoshikawa T: Role of metallothionein in coagulatory disturbance and systemic inflammation induced by lipopolysaccharide,  FASEB J, vol. 20, 533-535, 2006

 Inoue K, Takano H, Yanagisawa R, Hirano S, Ichinose T, Shimada A, Yoshikawa T: The role of toll like receptor-4 in airway inflammation induced by diesel exhaust particles, Arch Toxicol, vol. 80, 275-279, 2006

2005:

IInoue K, Takano H,Yanagisawa R, Sakurai M, Ueki N, Ichinose T, Sadakane K,Yoshino S, Uchiyama K, Yoshikawa T: Effects of 15-deoxy-△12,14-prostaglandin J2 on nuclear localization of GATA-3 in the murine lung in the presence of lipopolysaccharide. ArzneimForsch/DrugRes 55: 167-171, 2005.

Baba S, Osakabe N, Natsume M, Yasuda A, Muto Y, Hiyoshi K, Takano H, Terao J: Absorption, metabolism, degradation and urinary excretion of rosmarinic acid after intake of Perilla frutescens extract in humans. Eur J Nutr 18:1-9, 2005.

Hiyoshi K, Takano H, Inoue K, Ichinose T, Yanagisawa R, Tomura S, Cho AK, Froines JR, Kumagai Y: Effects of a single intratracheal administration of phenanthraquinone on murine lung..J Appl Toxicol 25: 47-51, 2005.

Inoue K, Takano H, Yanagisawa R, Sakurai M,Ichinose T, Sadakane K, Hiyoshi K, Sato M, Shimada A, Yoshikawa T. Role of metallothionein in antigen-related airway inflammation.  Exp Biol Med   (formerly: P  Soc Exp Biol Med) 230: 75-81, 2005.

Inoue K, Takano H,  Shimada A, Morita T, Yanagisawa R, Sakurai M,  Sato M,Yoshino S, Yoshikawa T: Cytoprotection by interleukin-6 against liver injury induced by lipopolysaccharide.  Int J Mol Med 15:221-224, 2005.

 Inoue K, Takano H, Yanagisawa R, Yoshikawa T. Vascular permeability in active pulmonary tuberculosis. Chest 127: 1076-1077, 2005.

 Ichinose T, Nishikawa M, Takano H, Nobuyuki S, Sadakane K, Mori I, Yanagisawa R, Oda T, Tamura H, Hiyoshi K, Quan H, Shibamoto T: Pulmonary toxicity induced by intratracheal instillation of Asian yellow dust (Kosa) in mice. Environ Toxicol Phar 20: 48-56, 2005.

 Inoue K, Takano H, Yanagisawa R, Ichinose T, Sadakane K, Yoshino S, Uchiyama K, Yoshikawa T. Effects of 15-deoxy-Δ12, 14-prostaglandin J2 on Toll-like receptor 4 and 2 expression in the murine lung in the presence of lipopolysaccharide. Clin Exp Pharmacol Physiol 32: 230-232, 2005.

Inoue K, Takano H, Yanagisawa R, Yoshikawa T. Eosinophilic pneumonia and arthritis. Chest 127: 2294-2295, 2005.

Naito Y, Takano H, Yoshikawa T: Oxidative stress-related molecules as a therapeutic target for inflammatory and allergic diseases. Current Drug Targets 4: 511-515, 2005.

Inoue K, Takano H, Yanagisawa R, Yoshikawa T. Interleukin-8 neutralization for COPD. Chest 128: 464-465, 2005

Yamaki K, Uchida H, Li X, Yanagisawa R. Takano H, Hayashi H, Mori Y, Yoshino S: Effect of varying types of anti-arthritic drugs on Th1 and Th2 immune responses in mice.  Int J Immunopathol Pharmacol 18: 133-144, 2005.

Inoue K, Takano H, H, Shimada A, Yanagisawa R, Sakurai M, Yoshino S, Sato H, Yoshikawa T. Urinary trypsin inhibitor protects against systemic inflammation induced by lipopolysaccharide. Mol Pharm 67: 673-680, 2005.

Inoue K, Takano H, Yanagisawa R, Yoshikawa T. Air pollution and pulmonary diseases. Chest 128: 1075, 2005

Inoue K, Takano H,  Yanagisawa R, Sakurai M, Shimada A, Yoshino S, Sato H, Yoshikawa T: Protective role of urinary trypsin inhibitor in acute lung injury induced by lipopolysaccharide.  Exp Biol Med  (formerly: P  Soc Exp Biol Med) 230: 281-287, 2005.

Hashimoto AH, Amanuma K, Hiyoshi K, Takano H, Masumura KI, Nohmi T, Aoki Y: In vivo mutagenesis induced by benzo[a]pyrene instilled into the lung of gpt delta transgenic mice. Environ Mol Mutagen 45: 363-373, 2005.

Inoue K, Takano H, Yoshikawa T, Satoh H. Protease-antiprotease imbalance in inflammatory diseases in the lung. Chest 128: 1069, 2005

Hiyoshi K, Ichinose T, Sadakane K, Takano H, Nishikawa M, Mori I, Yanagisawa R, Yoshida S, Kumagai Y, Tomura S, Shibamoto T. Asian Sand dust enhances ovalbumin-induced eosinophil recruitment in the alveoli and airway of mice. Environ Res. 99: 361-3688, 2005

Inoue K, Takano H, Yanagisawa R, Ichinose T, Shimada A,Yoshikawa T.Pulmonary exposure to diesel exhaust particles induce airway inflammation and cytokine expressin in NC/Nga mice. Arch Toxicol 79: 595-599, 2005.

Inoue K, Takano H, Shiga A, Fujita Y, Makino H, Yanagisawa R, Ichinose T,Kato Y, Yamada T, Yoshikawa T. Effects of volatile constituents of a rosemary extract on allergic airway inflammation related to house mite allergen in mice. Int J Mol Med 16: 315-319. 2005.

Yoshino S, Yamaki K, Tanada S, Yanagisawa R, Takano H: Reactivation of antigen-induced arthritis in mice by oral administration of lipopolysaccharide. Scan J of Immunol 62: 17-122, 2005.

Hiyoshi K, Takano H, Inoue K, Ichinose T, Yanagisawa R, Tomura S, Kumagai Y: Effects of phenanthraquinone on allergic airway inflammation in mice. Clin Exp Allergy 35: 1243-1248, 2005.

Fujimoto A, Tsukue N, Watanabe M, Sugawara I, Yanagisawa R, Takano H, Yoshida S, Takeda K. Diesel exhaust affects immunological action in the placentas of mice. Environ Toxicol. 20(4):431-440 , 2005.

Inoue K, Takano H, Yanagisawa R, Sakurai M, Ichinose T,Sadakane K, Yoshikawa T. Effects of nano particles on antigen-related airway inflammation in mice. Resp Res 6: 106, 2005.

Yamaki K, Khurshid Alam AHM, Aslam Hossain Md, Taneda S, Yanagisawa R, Takano H, Yoshino S.  Effect of rolipram, a phosphodiesterase IV inhibitor, on allergic footpad swelling using various adjuvants in mice.  Scand J Immunol 62: 378-384, 2005

Inoue K, Takano H,Takano H, Yanagisawa R, Sakurai M, Shimada A, Sato H, Kato Y, Yoshikawa T. Antioxidative role of urinarytrypsin inhibitor in acute lunginjury induced by lipopolysaccharide. Int J Mol Med 16: 1029-1033, 2005.

2004:

Osakabe N, Takano H, Sanbongi C, Yasuda A, Yanagisawa R, Inoue K, Yoshikawa T. Anti-inflammatory and anti-allergic effect of rosmarinic acid (RA); inhibition of seasonal allergic rhinoconjunctivitis (SAR) and its mechanism. Biofactors. 21: 127-131, 2004.

Yanagisawa R, Takano H, Inoue K, Ichinose T, Sadakane K,  Yoshida S, Takeda K, Yoshino S, Yamaki K, Kumagai Y, Yoshikawa T: Complementary DNA microarray analysis in acute lung injury induced by lipopolysaccharide and diesel exhaust particles. Exp Biol Med  (formerly: P  Soc Exp Biol Med) 229: 1081-1087, 2004.

Takano H,
Inoue K, Yoshikawa T, Yanagisawa R, Satoh M, Shimada A, Morita T, Sawada M, Nakamura K, Sanbongi C: Protective role of metallothionein in acute lung injury induced by bacterial endotoxin. Thorax 59: 1057-1062, 2004.

Naito Y, Takagi T, Uchiyama K, Kuroda M, Kokura S, Ichikawa H, Yanagisawa R, Inoue K, Takano H, Satoh M, Yoshida N, Okanoue T, Yoshikawa T. Reduced intestinal inflammation induced by dextran sodium sulfate in interleukin-6-deficient mice. Int J Mol Med 14(2):191-196, 2004.

Ichinose T, Nobuyuki S, Takano H, Abe M, Sadakane K, Yanagisawa R, Ochi H, Fujioka K, Leee K-G, Shibamoto T. Liver carcinogenesis and formation of 8-hydroxy-deoxyguanosine in C3H/HeN mice by oxidized dietary oils containing carcinogenic dicarbonyl compounds. Food and Chemical Toxicology 42: 1795-1803, 2004.

Yoshino S, Yamaki K, Xiaojuan Li, Sai T, Yanagisawa R, Takano H, Hayashi H, Mori Y: Prenatal exposure to bisphenol A upregulates immune responses including T helper 1 and T helper 2 responses in mice. Immunology 112, 489-495,2004.

Inoue K, Takano H, Yanagisawa R, Sakurai M, Yoshikawa T. The role of open-lung biopsy in ARDS. Chest 126: 1383-1384, 2004 (correspondence).

Inoue K, Takano H, Yanagisawa R, Uchiyama K, Yoshikawa T. Vitamin E as a regulator of host defense against infection. Chest 126: 1390, 2004. (correspondence).

Yamaki K, Li X, Alam AHM, Hossain H, Yanagisawa R, Takano H, Hayashi H, Taneda S, Mori Y, Yoshino S: Effects of the phosphodiesterase IV inhibitor rolipram on Th1 and Th2 immune responses in mice. J Pharm. Pharmacol 56: 877-882, 2004.

Inoue K, Takano H,  Yanagisawa R, Ichinose T, Sadakane K, Yoshino S, Yamaki K, Uchiyama K, Yoshikawa T: Components of diesel exhaust particles differently affect lung expression of cyclooxygenase-2 related to bacterial endotoxin. J Appl Toxicol 24: 415-418, 2004.

Inoue K, Takano H, Yanagisawa R, Sakurai M, Shimada A, Morita T, Satoh M, Yoshino S, Yoshikawa T, Tohyama C: Protective role of interleukin-6 in coagulatory and hemostatic disturbance induced by lipopolysaccharide in mice. Thrombosis and haemostasis 91: 1194-120, 2004.

Inoue K, Takano H, Yanagisawa R, Sakurai M, Yoshikawa T.Anti-inflammatory effect of pentoxifylline. Chest 125: 2365, 2004.

Sanbongi C, Takano H, Osakabe N, Sasa N, Natsume M, Yanagisawa R, Inoue K, Sadakane K, Ichinose T, Yoshikawa T: Rosmarinic acid in perilla extract inhibits allergic inflammation induced by mite allergen. CLin Exp Allergy 34: 971-977, 2004.

Ichinose T,
Takano H, Sadakane K, Yanagisawa R, Yoshikawa T, Sagai M, Shibamoto T: Mouse strain differences in eosinophilic airway-inflammation caused by intratracheal instillation of mite allergen and diesel exhaust particles. J Appl Toxicol 24: 69-76, 2004.

Inoue K,
Takano H, Yanagisawa R, Sakurai M, Yosikawa T: Statin, inflammation, and sepsis. Chest 125: 2365, 2004. correspondence)

Inoue K,
Takano H, Yanagisawa R, Morita M, Ichinose T, Sadakane K, Yoshino S, Yamaki K, Yoshikawa T: 15-deoxy-△12, 14-prostaglandin J2 enhances cyclooxygenase-2 expression in the murine lung in the presence of lipopolysaccharide. ArzneimForsch/DrugRes 54: 711-714, 2004.

Takano H, Osakabe N, Sanbongi C, Yanagisawa R, Inoue K, Yasuda A,  Natsume M, Baba S, Ichiishi E, Yoshikawa T: Extract of Perilla frutescens enriched for rosmarinic acid, a polyphenolic phytochemical, inhibits seasonal allergic rhinoconjunctivitis in humans. Exp Biol Med (formerly: P  Soc Exp Biol Med) 229: 247-254, 2004.

Takano H,
Yanagisawa R, Inoue K, Shimada A, Ichinose T, Sdakane K, Yoshino S, Yamaki K, Yoshikawa T. Nitrogen dioxide air pollution near ambient levels is an atherogenic risk, primarily in obese subjects. Exp Biol Med (formerly: P Soc Exp Biol Med) 229: 361-364, 2004.

Inoue K,
Takano H, Yosikawa T. Increased plasma interleukin-6 is associated with the pathogenesis of obstractive sleep apnea syndrome. Chest 125: 1965,2004. (correspondence)

Uchiyama K,
Takano H, Yanagisawa R, Inoue K, Naito Y, Yoshida N, Yamaki K, Yoshino S, Murase H, Yoshikawa T: Beneficial effects of a novel water-soluble vitamin E derivative, 2-(alpha-D-glucopyranosyl) methyl-2,5,7,8-tetramethylchroman-6-ol, on acute lung injury induced by bacterial endotoxin in mice. Clin Exp Pharmacol Physiol: 31: 226-230, 2004.

2003:

Yamaki K, Uchida H, Harada Y, Xiaojuan Li, Yanagisawa R, Takano H, Hayashi H, Taneda S, Mori Y, Yoshino S: Effect of methotrexate on Th1 and Th2 immune responses in mice. J Pharm Pharmacol 55: 1661-1666, 2003.

Inoue K,
Takano H, Yanagisawa R, Morita M, Ichinose T, Sadakane K, Yoshino S, Yamaki K, Uchiyama K, Yoshikawa T: Effect of 15-deoxy-△12, 14-PGJ2 on Acute Lung Injury Induced by Lipopolysaccaride in Mice. Eur J Pharmacol 481: 261-269, 2003.

Inoue K,
Takano H, Yoshikawa T: Interleukin-6, obstructive sleep apnea, and obesity. Chest 124: 1621-1323, 2003.

Tsunoda S,
Takano H, Inoue K, Yoshikawa T: A case of lupus peritonitis and cystitis after ovulation induction therapy. Am J Obstet Gynecol 189:888-889, 2003.

Yamaki K, Uchida H, Harada Y, Yanagisawa R,
Takano H, Hayashi Y, Mori Y, Yoshino S: Effect of the non-steroidal anti-inflammatory drug indomethacin on Th1 and Th2 immune responses in mice. J Pharm Sci 92: 1723-1729, 2003.

Yanagisawa R,
Takano H, Inoue K, Ichinose T, Sadakane K, Yoshino S, Yamaki, Kumagai Y, Uchiyama K, Yoshikawa T, Morita M: Enhancement of acute lunginjury related to bacterial endotoxin by components of diesel exhaustparticles. Thorax 58: 605-612, 2003.

Ichikawa H, Yoshida N,
Takano H, Ishikawa T, Handa O, Takagi T, Naito Y, Murase H, Yoshikawa T. A novel vitamin E derivative (TMG) protects against gastric mucosal damage induced by ischemia and reperfusion in rats. Dig Dis Sci 48: 54-58, 2003.

Ichinose T,
Takano H, Sadakane K, Yanagisawa R, Kawazato H, Sagai M, Shibamoto T: Differences in airway-inflammation development by house dust mite and diesel exhaust inhalation among mouse strains. Toxicol Applied Pharmacol 187: 29-37, 2003.

Inoue K, Kawahito Y, Sano H, Takano H, Yoshikawa T: New diagnostic tool for tumor angiogenesis. Chest 123: 966-967, 2003.

Inoue K,
Takano H, Kawahito Y, Sano H, Yoshikawa T: Cyclooxygenase-2 inhibitors in aspirin-induced asthma. Chest 123: 1317-1318, 2003.

Inoue K, Takano H, Yanagisawa R, Yoshikawa T: Effects of tumor necrosis factor-α inhibitors on lung lesions with rheumatoid arthritis. Chest (in press)

Inoue K,
Takano H, Yoshikawa T: Inflammatory chemokine in the pathogenesis of the common cold. Lancet 361: 782, 2003.

Sanbongi C,
Takano H, Osakabe N, Sasa N, Natsume M, Yanagisawa R, Inoue K, Yoshikawa T: Rosmarinic acid inhibits lung injury induced by diesel exhaust particles. Free Rad Biol Med 34: 1060-1069, 2003.

Yoshino S, Yamaki K, Yanagisawa R,
Takano H, Hayashi Y, Mori Y: Effects of bisphenol A on antigen-specific antibody production, proiferative responses of lymphoid cells, and TH1 and TH2 responses in mice. Br J Pharmacol 138:1271-1276, 2003.

2002:

Ichinose T, Takano H, Miyabara Y, Sagai M, Sadakane K, Shibamoto T: Diesels exhaust particles enhance antigen-induced eosinophilic inflammation in the airway of mast cell deficient mice. Toxicology 180: 293-301, 2002.

Sadakane K, Takano H, Ichinose T, Yanagisawa R, Shibamoto T: Formaldehyde enhances mite allergen-induced eosinophilic inflammation in the murine airway. J Environmental Pathology Toxicology and Oncology 21: 267-276, 2002. 

Ochiai J,
Takano H, Ichikawa H, Naito Y, Yoshida N, Yanagisawa R, Yoshino S, Murase H, Yoshikawa T: A novel water-soluble vitamin E derivative,2-(alpha-D-glucopyranosyl)methyl-2,5,7,8-tetramethylchroman-6-ol, protects against acute lung injury and mortality in endotoxemic rats. Shock 18: 580-584, 2002.

Takano H, Inoue K, Katada K, Yoshikawa T: Stenosis of pyloric antrum in a patient with systemic lupus erythematosus. Endoscopy 34(10): 846, 2002.

Inoue K,
Takano H, Yamada T, Tsuchida Y, Yoshikawa T: Nasogastric tubes in patients with dysphagia. Lancet 359: 81, 2002.

Takano H, Yanagisawa R, Ichinose T, Sadakane K, Yoshino S, Yoshikawa T, Morita M: Diesel exhaust particles enhance lung injury related to bacterial endotoxin through expression of proinflammatory cytokines, chemokines, and ICAM-1. Am J Respir Crit Care Med 165: 1329-1335, 2002.

Yoshino S, Hayashi H, Taneda S,
Takano H, Sagai M, Mori Y: Effects of diesel exhaust particle extracts on TH1 and TH2 immune response in mice. Int J Immunopathol Pharmacol 15: 13-18, 2002.

Sadakane K, Ichinose T,
Takano H, Yanagisawa R, Sagai M, Yoshikawa T, Shibamoto T: Murine strain differences in airway inflammation induced by Diesel exhaust particles and house dust mite allergen. Int Arch Allergy Immunol 128: 220-228, 2002.

Yoshino S, Hayashi H, Taneda S,
Takano H, Sagai M, Mori Y: Effect of diesel exhaust particle extracts on induction of oral tolerance in mice. Toxicol Sci Apr 66(2): 293-297, 2002.

Takano H, Yanagisawa R, Ichinose T, Sadakane K, Inoue K, Yoshida S, Takeda K, Yoshino S, Yoshikawa T, Morita M: Lung expresion of cytchrome P450 1A1 as a possible biomarker of exposure to diesel exhaust particles. Arch Toxicology 76: 146-151, 2002.

2001:

Inoue K, Takano H, Yoshikawa T: Fatty fish supplementation and risk of prostate cancer. Lancet 358: 1367, 2001.

Hashimoto K, Ishii Y, Uchida Y, Kimura T, Masuyama K, Morishima Y, Hirano K, Nomura A, Sakamoto T, Takano H, Sagai M, Sekizawa K: Exposure to diesel exhaust exacerbates allergen-induced asthmatic responses in guinea pigs. Am J Respir Crit Care Med 164: 1957-1963, 2001.

2000:

Takano H,
Satoh M, Shimada A, Sagai M, Yoshikawa T, Tohyama C: Cytoprotection by metallothionein against gastroduodenal mucosal injury caused by ethanol in mice. Lab Invest 80: 371-377, 2000.

1999:

Hongo H, Takano H, Imai A, Yamaguchi T, Boku Y, Fujii Y, Naito N, Yoshida N, Yoshikawa T, Kondo M: Pancreatic phosphalipase A2 induces bacterial translocation in rats. Immunopharmacol Immunotoxicol 21: 717-726, 1999.

Takano H, Lim HB, Miyabara Y, Ichinose T, Yoshikawa T, Sagai M: Manipulation of the L-arginine-nitric oxide pathway in airway inflammation induced by diesel exhaust particles in mice. Toxicology 139: 19-26, 1999.

Nishida K, Kaneko T, Yoneda M, Nakagawa S, Ishikawa T, Yamane E, Nishioka B, Miyamoto Y, Takano H, Yoshikawa T, Kondo M: Doubling time of serum CA 19-9 in the clinical course of patients with pancreatic cancer and its significant association with prognosis. J Surg Oncol 71: 140-146, 1999.

Arimoto T, Yoshikawa T, Takano H, Kohno M: Generation of reactive oxygen species and 8-hydroxy-2'-deoxyguanosine formation from diesel exhaust particle components in L1210 cells. Jpn J Pharmacol 80: 49-54, 1999.

1998:

Lim HB, Ichinose T, Miyabara Y, Takano H, Kumagai Y, Shimojo N, Devalia JL, Sagai M: Involvement of superoxide and nitric oxide on airway inflammation and hyperresponsiveness induced by diesel exhaust particles in mice. Free Radic Biol Med 25 (6): 635-644, 1998.

Ichinose T, Takano H, Miyabara Y, Sagai, M.: Long-term exposure to diesel exhaust enhances antigen-induced eosinophilic inflammation and epithelial damage in the murine airway. Toxicol Sciences (Fundam Appl Toxicol) 44: 70-79, 1998.

Miyabara Y, Ichinose T, Takano H, Lim HB, Sagai M: Effects of diesel exhaust on allergic airway inflammation in mice. J Allergy Clin Immunol 102: 805-812,1998.

Takano H, Lim HB, Miyabara Y, Ichinose T, Yoshikawa T, Sagai M: Oral administration of L-arginine potentiates allergen-induced airway inflammation and local expression of IL-5. J Pharmacol Exp Ther 286: 767-771, 1998.

Takano H, Ichinose T, Miyabara Y, Shibuya T, Lim HB, Yoshikawa T, Sagai M: Inhalation of diesel exhaust enhances allergen-induced eosinophil recruitment and airway hyperresponsiveness in mice. Toxicol Applied Pharmacol 150: 328-337,1998.

Miyabara Y, Ichinose T, Takano H, Sagai M: Diesel exhaust inhalation enhances airway hyperresponsiveness in mice. Int Arch Allergy Immun 116: 124-131, 1998.

Takano H, Ichinose T, Miyabara Y, Yoshikawa T, Sagai M: Diesel exhaust particles enhance airway responsiveness following allergen exposure in mice. Immunopharmacol Immunotoxicol 20:329-336, 1998.

Miyabara Y, Takano H, Ichinose T, Lim HB, Sagai M: Diesel exhaust enhances allergic airway inflammation and hyperresponsiveness in mice. Am J Respir Crit Care Med 157: 1138-1144, 1998.

Miyabara Y, Yanagisawa R, Shimojo N, Takano H, Lim HB, Ichinose T, Sagai M: Murine strain differences in airway inflammation caused by diesel exhaust particles. Eur Respir J 11: 291-298, 1998.

1997:

Kokura S, Yoshikawa T, Naito Y, Ichikawa H, Takano H, Takahashi S, Tomii T, Yoshida N, Kondo M: Effects of rebamipide, a novel anti-ulcer agent, on gastric mucosal injury induced by platelet-activatinf factor in rats. Dig Dis Sci 42: 2566-2571, 1997.

Ichinose T, Takano H, Miyabara Y, Yanagisawa R, Sagai M: Murine strain difference in allergic airway inflammation and immunogloburin production by a combination of antigen and diesel exhaust particles. Toxicology 122: 183-192, 1997.

Takano H, Yoshikawa T, Ichinose T, Miyabara Y, Imaoka K, Sagai M: Diesel exhaust particles enhance antigen-induced airway inflammation and local cytokine expression in mice. Am J Respir Crit Care Med 156: 36-42, 1997.

Takano H, Yoshikawa T, Yamaguchi T, Hongo H, Fujii T, Boku Y, Yamamoto H, Yoshihida N, Nakahashi Y, Yanagisawa R, Kondo M: Effects of aminoguanidine on systemic inflammatory response syndrome induced by platelet activating factor and by lipopolysaccharide in rats. Eur J Pharmacol 323: 107-110, 1997.

Yoshikawa T, Takano H, Yamamoto H, Nakahashi Y, Yamaguchi T, Arimoto T, Kondo M: Role of superoxide and nitric oxide in platelet activating factor-induced acute lung injury, hypotension, and lethality in rats. Crit Care Med 25: 286-292, 1997.


邦文・総説

2006:

高野裕久、吉川敏一:基礎から学ぶ侵襲と生体反応 生体反応を担うメデイエータ 活 性酸素種/NO 救急医学 (印刷中)

井上健一郎、高野裕久、柳澤利枝、島田章則、吉川敏一:炎症に伴う凝固・線溶異常におけるIL-6の保護的役割 炎症 26: 40-43, 2006.


高野裕久:シックハウス症候群・化学物質過敏症の診療とその課題 環境技術 (印刷中)

高野裕久、井上健一郎、柳澤利枝:UTIによる局所および全身性急性期炎症反応制御の試み ―ノックアウトマウスを用いた実験的検討―侵襲と免疫(印刷中)

井上健一郎、高野裕久、柳澤利枝、吉川敏一:ナノ粒子のアレルギー性気道炎症への影響 アレルギーの臨床(印刷中)

2004:

吉川敏一、高野裕久 臨床病態とプロテアーゼインヒビタープロテアーゼ・インヒビターによる急性肺傷害の治療の可能性とその投与タイミング 医薬の門 44: 3-8, 2004.


2003:

高野裕久、
吉川敏一: 環境汚染とアレルギー 化学物質によるアレルギーの修飾アレルギー科 16: 403-411, 2003.

高野裕久、柳澤利枝、井上健一郎、吉川敏一:急性肺傷害と酸化ストレス ICUとCCU 27: 661-668, 2003.

高野裕久:アレルギー疾患と環境因子 Meiji's Front Page 4: 1-4, 2003.

高野裕久、柳澤利枝、井上健一郎、吉川敏一: フサンとサイトカインープロテアーゼインヒビターによる臓器傷害の防御とサイトカイン制御の意義ー 医薬の門 43: 303-309, 2003.

2002:

高野裕久、柳澤利枝、井上健一郎、吉川敏一: 補体からみたショックとDICの病態 医薬の門 42:768-774, 2002.

高野裕久、柳澤利枝、井上健一郎、吉川敏一: DIC:病態の解明と治療の最前線 補体とDIC 医薬の門 42: 342-348, 2002.

高野裕久、吉川敏一: 感染症の経過とプロテアーゼ・インヒビター投与のタイミングについて メビオ 19: 131-133, 2002.

2001:

高野裕久、
柳澤利枝、遠藤敦、吉川敏一: プロテアーゼとそのインヒビター 補体とそのカスケード 医学のあゆみ 198: 39-44, 2001.

高野裕久、柳澤利枝、遠藤敦、吉川敏一: 播種性血管内凝固症候群と活性酸素血液フロンテイア 11: 745-753, 2001.

高野裕久、柳澤利枝、遠藤敦、吉川敏一: フリーラジカルに関する基礎事項 フリーラジカルスカベンジャー 臨床神経科学 19: 536-538, 2001.

1999:

近藤元治、高野裕久、吉川敏一: 複数臓器に関与する病態と細胞死におけるフリーラジカルの役割 現代医療 31: 2502-2511, 1999.

吉川敏一、高野裕久、近藤元治: 呼吸器傷害におけるNOの功罪. 日本救急医学会雑誌 10: 590-598, 1999.

高野裕久、吉川敏一、近藤元治: 大気汚染と気管支喘息. 喘息 12: 19-25, 1999.

高野裕久、吉川敏一、近藤元治: ショック、急性肺傷害、気道炎症とNO. 細胞培養工学 25: 154-157, 1999.

高野裕久、 デイーゼル排気微粒子はアレルゲンによる好酸球性気道炎症とサイトカイン発現を修飾する. 炎症 19: 9-18, 1999.

1998:

吉川敏一、高野裕久、吉田憲正: ショックの病態と最新の治療. 活性酸素・フリーラジカル. 現代医療 30: 3149-3154, 1998.

吉川敏一、高野裕久、近藤元治: 集中治療とフリーラジカル. 集中治療 10: e222-227, 1998.

吉川敏一、高野裕久、近藤元治: 虚血・再潅流傷害を見直すーフリーラジカル、NO、アポトーシスの立場からー. 集中治療 10: 415-425, 1998.

1997:

高野裕久、
吉川敏一、近藤元治: 活性酸素・フリーラジカルからみた臓器相互作用. 集中治療 9: 872-879, 1997.

高野裕久、宮原裕一、市瀬孝道、嵯峨井勝: デイーゼル排気微粒子によるアレルギーの増悪とその機序. 臨床免疫 29: 1526-1532, 1997.

吉川敏一、高野裕久: 急性臓器不全とradicals. 医薬の門 37: 127-132, 1997.

吉川敏一、高野裕久、近藤元治: 肺組織傷害とNO. 炎症と免疫 5: 138-143, 1997.

高野裕久、市瀬孝道、嵯峨井勝:デイーゼル排気ガスによる呼吸器障害の分子機構 分子呼吸器病 1: 145-147, 1997.

吉川敏一、高野裕久、近藤元治: 内科医のための救急疾患キーワードー活性酸素ー 診断と治療 85: 656-658, 1997.


邦文・著書

2006:

有本豊子、高野裕久、井上健一郎、柳澤利枝、桜井美穂、河野浩之、吉川敏一:局所及び全身急性期炎症反応における内因性ウリナスタチン (UTI) の役割 「エンドトキシン研究9」日本エンドトキシン研究会 編  1, 医学図書出版 東京 2006 (印刷中)

高野裕久:2.1. 環境因子 「アンチエイジング医学」診断と治療社 東京 (印刷中)


2005:

井上健一郎、高野裕久、柳澤利枝、田村弘志、小田俊男、大野尚仁、安達禎之、吉川敏一:可溶化βグルカンの経気道曝露による気道炎症 「エンドトキシン研究」 1-11, 医学図書出版, 東京, 2005. 

高野裕久:呼吸器・循環器影響の疫学 「自動車排出ナノ粒子およびDEPの測定と生体影響評価」177-186 NTS 東京 2005

高野裕久:シックハウス症候群の診断と治療「シックハウス症候群とその対策」57-66, 吉川敏一編 オーム社 東京 2005

高野裕久、吉川敏一、嵯峨井勝:ビタミンEと大気汚染 「ビタミンEの臨床」平井俊策編 105-114 医薬ジャーナル社 大阪 2005

高野裕久:5.2. 感染症、免疫・アレルギー疾患 B. 免疫・アレルギー疾患 「臨床栄養管理学」講談社サイエンテイフイク. 131-136 東京 2005

森田昌敏、高野裕久:「環境と健康」(環境とアレルギーp. 109-145/232を高野が分担) 岩波書店 東京 2005

高野裕久:環境 131. DEP 「予防医学事典」 291-293 朝倉書店 東京 2005



2003:

高野裕久:
各論3. 環境医学 4. 大気汚染物質 b. デイーゼル排ガスおよび排ガス中微粒子 「分子予防環境医学」 544-554 本の泉社 東京 2003

吉川敏一、井上健一郎、
高野裕久:炎症に関与する細胞・分子 「内科学」pp 27-31 朝倉書店 東京 2003

高野裕久:デイーゼル排気微粒子によるエンドトキシン関連肺傷害の増悪 「エンドトキシン研究」 10-17, 医学図書出版, 東京, 2003.

2001:

高野裕久、
柳澤利枝、市瀬孝道、定金香里、吉川敏一: デイーゼル排気微粒子はエンドトキシンによる急性肺傷害を増悪する 「エンドトキシン研究」 4: 139-144, 医学図書出版 東京, 2001.

高野裕久、柳澤利枝、遠藤敦、吉川敏一: 急性肺傷害と酸化ストレス 「別冊・医学のあゆみ」, 278-281, 医歯薬出版, 東京, 2001.

高野裕久、柳澤利枝、遠藤敦、吉川敏一: 臨床におけるフリーラジカルスカベンジャー 「食品機能素材II, 53-63, シーエムシー, 東京, 2001.

1999:

高野裕久、
吉川敏一、近藤元治、市瀬孝道、宮原裕一、嵯峨井勝: 気管支喘息におけるL-arginine-nitric oxide pathwayの役割 「Cytoprotection and biology」 17: 41-44, 癌と化学療法社 東京, 1999.

高野裕久総合討論、 「アレルギー性疾患の増加因子」 ライフサイエンス出版 東京 , 1999, P151-165.

高野裕久2.環境因子 討論、 「アレルギー性疾患の増加因子」 ライフサイエンス出版 東京 , 1999, P39-46.

高野裕久2. 環境因子1. 大気汚染物質、 「アレルギー性疾患の増加因子」 ライフサイエンス出版 東京 , 1999, P19-24.

1998:

高野裕久、
吉川敏一、近藤元治: ARDSとその治療 「敗血症の新しい展開」, 舟田久 編 医薬ジャーナル社 大阪, 1998, P108-115.

高野裕久、吉川敏一、近藤元治: ショック、多臓器不全 「抗酸化物質のすべて」, 吉川敏一 編 先端医学社. 東京, 1998, P314-319.

山口泰司、高野裕久、吉川敏一、吉田憲正、近藤元治: systemic inflammatory response syndromeにおける活性酸素、NOの作用 「エンドトキシン研究1」 日本エンドトキシン研究会編 菜根出版 東京, 1998, P75-81.

吉川敏一、高野裕久: 生体反応の分子機構 NO「臨床侵襲学」, 小川道雄、齋藤英昭編 へるす出版 東京, 1998, P204-212.

1997:

西田康一、兼子俊朗、米田充、築田千穂、石川剛、田中亮、朴義男、吉田憲正、高野裕久、吉川敏一、近藤元治: 内視鏡下胃生検組織を用いた胃炎、胃潰瘍、胃ポリープおよび胃癌組織における癌抑制遺伝子p53の検索(フローサイトメトリーによる検討とDNA ploidyパターンの比較), 「消化器と免疫 33」, 日比紀文 他 編, マイライフ社, 東京, 1997, P183-193.


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