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The World of Protozoa, Rotifera, Nematoda and Oligochaeta

Polynitro-organic contaminants (PNOs)

[CL-20]

= 2,4,6,8,10,12-Hexanitro-2,4,6,8,10,12-hexazaisowurtzitane CAS[135285-90-4], = Nitramine

Trade name

CL-20

Purpose for use

Energetic compound (polycyclic nitramine explosive).

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
Oligochaeta: Eisenia andrei (ref. ID; 4572)

[Monocyclic nitramine explosives]

HMX

= Octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine CAS[2691-41-0], = 1,3,5,7-Tetranitro-1,3,5,7-tetrazacyclo-octane (ref. ID; 6865)

Purpose for use

High melting explosive.

Toxicity

This explosive is toxic to some aquatic organisms, including fathead minnows (Pimephales promelas) and the freshwater microcrustacean Daphnia magna, and some terrestrial organisms including mice and rats. But, HMX is not toxic to the bioluminescent bacteria Vibrio fisheri and is not cytotoxic or mutagenic to bacterial and mammalian cells in aqueous solutions of HMX. (ref. ID; 6115)

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
Oligochaeta: Eisenia andrei (ref. ID; 4958, 6115, 6817)
Oligochaeta: Lumbricus terrestris (ref. ID; 4958)

RDX

= 1,3,5-Trinitro-1,3,5-triazacyclohexane CAS[121-82-4] (ref. ID; 4958, 6817), = 1,3,5-Trinitro-1,3,5,7-triazacyclohexane (ref. ID; 6865), = Hexahydro-1,3,5-trinitro-1,3,5-triazine (ref. ID; 6927)

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
Oligochaeta: Eisenia andrei (ref. ID; 4958, 6817, 6927)
Oligochaeta: Lumbricus terrestris (ref. ID; 4958)

RDX metabolites

TNT

= 2,4,6-Trinitrotoluene CAS[118-96-7]

TNT metabolites

Biotransformation of TNT has been demonstrated in bacteria, fungi, plants, mammals and humans. The nitro-reduction of TNT into monoamino metabolites ([2-ADNT] and [4-ADNT] and then into diamino metabolites [2,4-DANT] and [2,6-DANT]) was the major metabolic pathway observed. (ref. ID; 7030)

Purpose for use

Energetic compounds.
TNT has been identified in soil at sites related to military activities. (ref. ID; 7030)

Toxicity

Mutagenicity/Carcinogenic. (ref. ID; 7030)

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 7772)
Oligochaeta: Eisenia andrei (ref. ID; 4958, 6817, 6865, 7030)
Oligochaeta: Enchytraeus albidus (ref. ID; 6130)
Oligochaeta: Lumbricus terrestris (ref. ID; 4958)

2-Amino-4,6-dinitrotoluene (2-ADNT) CAS[35572-78-2]

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

2-Hydroxyamino-4,6-dinitrotoluene (2-HADNT)

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

4-Hydroxyamino-2,6-dinitrotoluene (4-HADNT)

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 7772)

Other products of TNT manufacture


[Tetryl]

Test organisms

Protozoa: Tetrahymena pyriformis (ref. ID; 7772)