Drugs & medicine
[Acetylsalicylic acid] CAS[50-78-2] UN2811
Chemical formula
HOOCC6H4OCOCH3
Test organisms
Oligochaeta: Eisenia foetida (ref. ID; 7012, 7182)
[Amidantel (ADT or BAY d 8815) and its deacylated derivative (dADT or BAY d 9216)]
= N-(4(1-(dimethylamino)-ethylidene)-amino))-2-methoxyacetamide hydrochloride
Purpose for use
Amidantel is one of a new class of p-aminophenylamidine-based anthelmintic drugs. The drug was effective against filariae, hookworms, ascarids, and pinworms in rats and dogs. (ref. ID; 7249)
Test organisms
Oligochaeta: Caenorhabditis elegans (ref. ID; 7249)
[Antimycin A]
Test organisms
Protozoa: Loxodes striatus (ref. ID; 500)
[Benactyzine]
Pharmacological activity
Cholinergic blocker. (ref. ID; 1668)
Test organisms
Rotifera: Brachionus plicatilis (ref. ID; 1668)
[Bupivacaine]
Pharmacological activity
Local anesthetic. (ref. ID; 1668)
Test organisms
Rotifera: Brachionus plicatilis (ref. ID; 1668)
[Caffeine]
Test organisms
Oligochaeta: Eisenia foetida (ref. ID; 7012)
[Chloral hydrate]
= Trichloroacetaldehyde Monohydrate CAS[302-17-0] UN2811
Chemical formula
CCl3CHO/H2O
Pharmacological activity
General anesthetic. (ref. ID; 1668)
Test organisms
Rotifera: Brachionus plicatilis (ref. ID; 1668)
[Chloretone]
= 1,1,1-Trichloro-2-methyl-2-propanol Hemihydrate CAS[6001-64-5]
Chemical formula
Cl3CC(CH3)2OH/0.5H2O
Pharmacological activity
General anesthetic. (ref. ID; 1668)
Test organisms
Rotifera: Brachionus plicatilis (ref. ID; 1668)
[Chlorpromazine (CPZ)] CAS[69-09-0]
= 2-Chloro-10-[3-dimethylaminopropyl]phenothiazine
Purpose for use
Antipsychotic drug. (ref. ID; 4084)
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 4084)
[Ciprofloxacin (Pharmaceutical mixtures)]
Purpose for use
A DNA gyrase-inhibiting antibiotic. (ref. ID; 4573)
Test system
Aquatic microcosms (ref. ID; 4573)
[Colchicine] CAS[64-86-8] UN1544
Chemical formula
C22H25NO6
Test organisms
Protozoa: Oxytricha bifaria (ref. ID; 651)
Protozoa: Spirostomum ambiguum (ref. ID; 7202)
[Decamethonium]
Pharmacological activity
Neuromuscular blocker. (ref. ID; 1668)
Test organisms
Rotifera: Brachionus plicatilis (ref. ID; 1668)
[EDTA (Ethylenediaminetetraacetic acid)] CAS[60-00-4]
Chemical formula
C10H16N2O8
Pharmacological activity
Calcium antagonists. (ref. ID; 1668)
Test organisms
Green algae (formerly including protozoa): Chlamydomonas reinhardtii (ref. ID; 3904)
Rotifera: Brachionus plicatilis (ref. ID; 1668)
[Eserine salicylate] CAS[57-64-7]
Chemical formula
C15H21N3O2/C7H6O3
Purpose for use
Cabamate drug. (ref. ID; 7012)
Test organisms
Oligochaeta: Eisenia foetida (ref. ID; 7012)
[Fluoxetine (Pharmaceutical mixtures)]
Purpose for use
A selective serotonin reuptake inhibitor. (ref. ID; 4573)
Test system
Aquatic microcosms (ref. ID; 4573)
[Hydroxylamine]
Pharmacological activity
Unknown. (ref. ID; 1668)
Test organisms
Rotifera: Brachionus plicatilis (ref. ID; 1668)
[Ibuprofen (Pharmaceutical mixtures)] CAS[15687-27-1]
Chemical formula
C13H18O2
Purpose for use
A nonsteroidal anti-inflammatory drug. (ref. ID; 4573)
Toxicity
LD50 (oral): mouse (male) 1255 mg/kg, rat 1050 mg/l.
Test systems
Aquatic microcosms (ref. ID; 4573)
[Ivermectin] CAS[70288-86-7]
= 22,23-dihydroavermectin B(1a)
Chemical formula
C48H74O14
Purpose for use
Ivermectin, a semisynthetic avermectin analog, is a potent anthelmintic and insecticide used on nematode and arthropod parasites. It is widely used to improve the health care of domestic animals and humans. (ref. ID; 6000)
Test organisms
Oligochaeta: Lumbriculus variegatus (ref. ID; 6000)
[K-oxalate]
Pharmacological activity
Calcium antagonists. (ref. ID; 1668)
Test organisms
Rotifera: Brachionus plicatilis (ref. ID; 1668)
[Lidocaine] CAS[137-58-6]
Chemical formula
C14H22N2O
Pharmacological activity
Local anesthetic. (ref. ID; 1668)
Test organisms
Rotifera: Brachionus plicatilis (ref. ID; 1668)
[Penfluridol]
Purpose for use
Antipsychotic drug. (ref. ID; 4084)
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 4084)
[Phenmetrazine]
Test organisms
Oligochaeta: Eisenia foetida (ref. ID; 7012)
[Pimozide] CAS[2062-78-4]
= 1-[1-(4,4-bis[4-Fluorophenyl]-butyl)-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one
Purpose for use
Antipsychotic drug. (ref. ID; 4084)
Test organisms
Protozoa: Tetrahymena pyriformis (ref. ID; 4084)
[Procaine] CAS[59-46-1]
Chemical formula
C13H20N2O2
Pharmacological activity
Local anesthetic. (ref. ID; 1668)
Test organisms
Rotifera: Brachionus plicatilis (ref. ID; 1668)
[Propranolol]
Pharmacological activity
beta-adrenergic blocker. (ref. ID; 1668)
Test organisms
Rotifera: Brachionus plicatilis (ref. ID; 1668)
[Rotenone] CAS[83-79-4]
Chemical formula
C23H22O6
Test organisms
Protozoa: Loxodes striatus (ref. ID; 500)
[Theophylline] CAS[58-55-9] UN2811
Chemical formula
C7H8N4O2
Test organisms
Oligochaeta: Eisenia foetida (ref. ID; 7012)
[Tricaine]
Pharmacological activity
Local anesthetic. (ref. ID; 1668)
Test organisms
Rotifera: Brachionus plicatilis (ref. ID; 1668)
[Vincristine (VCR)] CAS[57-22-7]
= Leurocristine
Chemical formula
C46H56N4O10
Test organisms
Protozoa: Oxytricha bifaria (ref. ID; 651)